Assuntos
Artrite Infecciosa/diagnóstico , Articulação do Joelho , Infecções Estafilocócicas/tratamento farmacológico , Antibacterianos/uso terapêutico , Artrite Infecciosa/tratamento farmacológico , Artrite Infecciosa/microbiologia , Criança , Feminino , Seguimentos , Humanos , Imageamento por Ressonância Magnética/métodos , Medição da Dor , Remissão Espontânea , Medição de Risco , Infecções Estafilocócicas/diagnóstico , Staphylococcus aureus/isolamento & purificação , Tomografia Computadorizada por Raios XRESUMO
A 28-year-old patient presented with severe intrauterine fetal growth retardation (IUGR) at 34 weeks' gestation. There was a prior history of a recurrent cutaneous ulcer on the left thigh. Serological tests for IgG anticardiolipin antibody were positive. A live premature male infant was delivered by an urgent cesarean section because of fetal distress. Histopathological examination revealed that the causes of the cutaneous ulcer and IUGR were thrombosis of the small blood vessels and placental infarction, respectively. Early diagnosis and proper treatment are important in the management of the antiphospholipid syndrome.
Assuntos
Síndrome Antifosfolipídica/patologia , Retardo do Crescimento Fetal/patologia , Complicações na Gravidez/diagnóstico , Resultado da Gravidez , Úlcera Cutânea/patologia , Adulto , Síndrome Antifosfolipídica/complicações , Biópsia por Agulha , Cesárea , Feminino , Retardo do Crescimento Fetal/complicações , Seguimentos , Idade Gestacional , Humanos , Imuno-Histoquímica , Gravidez , Medição de Risco , Úlcera Cutânea/complicaçõesRESUMO
The patient was a 48-year-old man who had a history of colonic polyps. About 18 months before, a dark reddish nodule had appeared on his right forearm. By peripheral growth, this lesion had formed a crateriform prominence with central healing. Similar symptoms multiplied and expanded, the largest being about the size of a child's head. Given both the clinical and histologic evidence, a diagnosis of keratoacanthoma centrifugum marginatum (KCM) was made. Oral etretinate was administered, and an involution of verrucous plaque began after 4 weeks. After 8 weeks, the lesions faded, leaving pigmentation in some areas. This is a rare disorder, only 30 such cases having been reported worldwide, and the present case was the third in which oral etretinate was found to be effective.
