[Current Practice of Dealing with Comorbid Problematic Substance Use in Non-Specialized Rehabilitation Settings: A Survey in German Somatic and Psychosomatic Rehabilitation Centres]. / Gegenwärtige Praxis des Umgangs mit komorbidem problematischem Suchtmittelkonsum in nicht auf Sucht spezialisierten Rehabilitationseinrichtungen--Ergebnisse einer deutschlandweiten Befragung.

STUDY OBJECTIVE: The current practice of dealing with comorbid problematic substance use in non-specialized somatic and psychosomatic rehabilitation centres is described. METHODS: A nationwide survey of rehabilitation centres across all indications was conducted. RESULTS: Incidents related to substance use within the past 12 months were reported by every centre participating in the survey. Even though these incidents occurred rather infrequently, 85% of the respondents stated that the opportunity should be used to address the topic of problematic substance use with all patients. At the same time the issue is discussed controversially by staff members in 42% of the centres, and 29% of the respondents state that there is a need to change the way this issue is dealt with. CONCLUSION: It seems necessary to strengthen the awareness of the problem as well as the professional confidence in dealing with it. In order to support identification of and dealing with problematic substance use, appropriate practice guidelines for the somatic and psychosomatic rehabilitation settings are needed. The present survey constitutes a basis for developing such practice guidelines.

Cracks in the beta-can: fluorescent proteins from Anemonia sulcata (Anthozoa, Actinaria).

We characterize two green fluorescent proteins (GFPs), an orange fluorescent protein, and a nonfluorescent red protein isolated from the sea anemone Anemonia sulcata. The orange fluorescent protein and the red protein seem to represent two different states of the same protein. Furthermore, we describe the cloning of a GFP and a nonfluorescent red protein. Both proteins are homologous to the GFP from Aequorea victoria. The red protein is significantly smaller than other GFP homologues, and the formation of a closed GFP-like beta-can is not possible. Nevertheless, the primary structure of the red protein carries all features necessary for orange fluorescence. We discuss a type of beta-can that could be formed in a multimerization process.

The significance of diagnostic imaging in acute and chronic brain damage in boxing. A prospective study in amateur boxing using magnetic resonance imaging (MRI).

The significance and possible extent of structural damage to the central nervous system (CNS) due to boxing are investigated. Bleeding, especially microhematomas, is considered to be one probable cause of the chronic encephalopathy in boxers. In a prospective study, 13 amateur boxers were investigated with the help of MRI several times before and after their fights. The MRI investigations were accompanied by neurologic examinations before and after the fights. Among the 13 boxes, 5 demonstrated focal neurological signs following the fights, without evidence of small hematoma or other structural alterations. The number of head punches did not correlate with the occurrence of neurologic signs. These results indicate that up to now imaging methods cannot clarify the development of chronic encephalopathy.

[Electrode model for multiaxonal stimulation of the acoustic nerve (author's transl)]. / Modell einer Elektrode zur multiaxonalen Reizung des Nervus acusticus.

An electrode arrangement is described, which allows an isolated stimulation of 25--50 singular axons: By laser beams a small ceramic plate got 25--50 perforations through which glass isolated platin wires were so fixed that they end like a brush. Only the tips of the "hairs" are not isolated. The diameter of the electrodes is approximately 10 micrometer, the length ranges between 0,5 and 1,5 mm. This electrode system is enough stabile to be pressed into a hard boiled egg without being damaged.