RESUMO
BACKGROUND: The purpose of the study was to quantify changes in the quality of life of small bowel recipients before and after transplantation and of home parenteral nutrition (HPN)-dependent patients before and after therapy. We examined quality of life across multiple areas of function including physical, social, and emotional indices. METHODS: The Quality of Life Instrument in the form of a self-administered questionnaire was completed voluntarily by the recipients of small intestinal transplants and by a cohort of HPN-dependent patients. RESULTS: Small intestinal transplant recipients reported significant improvement in the quality of their life and function. They also rated their quality of life and function during the pretransplant, TPN-dependent period to be worse than before the development of chronic intestinal failure. Similarly, HPN recipients reported significant worsening across most areas of quality of life when they compared their premorbid period to the HPN-dependent state. CONCLUSIONS: TPN dependence causes significant impairment in the quality of life in most areas of functioning. In contrast, small intestinal transplantation restores the quality of life among recipients with functioning grafts.
Assuntos
Intestino Delgado/transplante , Nutrição Parenteral Total no Domicílio , Qualidade de Vida , Adulto , Estudos de Coortes , Feminino , Humanos , Masculino , Período Pós-Operatório , Perfil de Impacto da Doença , Inquéritos e QuestionáriosAssuntos
Hospitalização , Intestino Delgado/transplante , Transplante de Fígado , Readmissão do Paciente , Complicações Pós-Operatórias/epidemiologia , Adulto , Fatores Etários , Criança , Infecções por Citomegalovirus/epidemiologia , Desidratação/epidemiologia , Seguimentos , Rejeição de Enxerto/epidemiologia , Humanos , Tempo de Internação , Infecções Oportunistas/epidemiologia , Sepse/epidemiologiaAssuntos
Transtornos da Alimentação e da Ingestão de Alimentos/etiologia , Intestino Delgado/transplante , Fenômenos Fisiológicos da Nutrição , Criança , Transtornos da Alimentação e da Ingestão de Alimentos/epidemiologia , Transtornos da Alimentação e da Ingestão de Alimentos/terapia , Seguimentos , Motilidade Gastrointestinal , Rejeição de Enxerto , Humanos , Nutrição Parenteral Total , Equipe de Assistência ao Paciente , Fatores de TempoRESUMO
Intestinal transplantation has become a viable treatment modality for the patient with short gut syndrome. The potential for the development of serious postoperative complications contributes to the complexity of caring for these patients. Through astute observation, thorough assessment, and intelligent intervention, the nurse can directly affect the ultimate success of intestinal transplantation. A dedicated team approach, along with a sincere patient/family commitment, will help to provide for optimal patient management and a successful outcome.