Osseointegrated dental implants that will undergo radiotherapy. Does risk of osteoradionecrosis exist? A scoping review.

OBJECTIVE: Given the absence of a standardized action protocol for treating patients with dental implants (DIs) who are subjected to radiotherapy (RT), we have conducted an extensive review and analysis of published literature on this subject. Our objective is to gain a comprehensive understanding of the impact of RT on the bone surrounding osseointegrated implants during and after treatment. STUDY DESIGN: We conducted a literature review using PubMed (MEDLINE) to identify studies describing the effects of RT on preexisting osseointegrated and/or loaded DIs. Articles published between January 1963 and December 2023 were considered for inclusion. RESULTS: A total of 1,126 articles were retrieved, 64 full articles were reviewed, and only 13 articles were included in this review upon meeting the criteria. A total of 667 patients and 2,409 implants were included. Osteoradionecrosis (ORN) was observed in approximately 19 implants following antineoplastic treatment. CONCLUSIONS: The interaction between DIs and RT is a complex and multifaceted issue that requires further research and clinical guidance. Although certain studies indicate a possible connection between DIs, radiation, and ORN risk, the precise relationship remains unclear. Factors such as radiation dosage, implant characteristics, material, and timing of placement significantly influence this association.

IS THE PHOTOBIOMODULATION THERAPY EFFECTIVE IN CONTROLLING POST-SURGICAL SIDE EFFECTS AFTER THE EXTRACTION OF MANDIBULAR THIRD MOLARS? A SYSTEMATIC REVIEW AND META-ANALYSIS.

OBJECTIVES: The extraction of third molars is one of the most performed surgical procedures in oral and maxillofacial surgery. Pain, oedema, and trismus are the most frequently complications related in the surgical postoperative period. The literature has indicated PBM as a potential adjuvant method to reduce these complications. The aim of this review and meta-analysis is evaluate the PBM, as an optimal method to improve patient experience and minimize postoperative morbidity. Additionally, we seek to determine which wavelength, site, and frequency of application are most effective. METHODS: This review was registered in PROSPERO (CRD42023429966) and followed PRISMA guidelines. The search was carried out in the main databases, PubMed/MEDLINE, Cochrane Library, Embase, Scopus, and Lilacs, including reviews in the most important journals in the area of oral surgery and laser applied to oral surgery. In addition, all article references and also gray literature were reviewed. After the studies selection, the relevant data was collected. All the studies were randomized controlled trials and the patients were allocated into two groups: active PBM and inactive PBM. The statistical analysis was carried out using Stata v.16, and the methodological quality and risk of bias were assessed by the Jadad scale and RoB 2.0, respectively. RESULTS: Where included 22 studies and 989 subjects, to all with a minimum follow-up of 7 days. Pain and oedema showed statistically significant results in favor to the active PBM group. Especially when laser applied in infrared mode, for pain and oedema at 48 h, MD = -1.80 (CI95% -2.88, -0.72) I²â€¯= 92.13% and MD = -1.45 (CI95% -2.42, -0.48) I²â€¯= 65.01%, respectively. The same is not true for trismus at 48 h, MD = 0.07 (CI95% -0.06, 0.21) I²â€¯= 3.26%. The meta-analysis also presented results in respect of laser site of application and number of PBM sessions. CONCLUSIONS: PBM with infrared laser, in a combination intraoral and extraoral application, in one session in the immediate postoperative period, has been shown to be effective to achieve the objectives of reducing pain and oedema after third molar extraction.

OralImmunoAnalyser: a software tool for immunohistochemical assessment of oral leukoplakia using image segmentation and classification models.

Oral cancer ranks sixteenth amongst types of cancer by number of deaths. Many oral cancers are developed from potentially malignant disorders such as oral leukoplakia, whose most frequent predictor is the presence of epithelial dysplasia. Immunohistochemical staining using cell proliferation biomarkers such as ki67 is a complementary technique to improve the diagnosis and prognosis of oral leukoplakia. The cell counting of these images was traditionally done manually, which is time-consuming and not very reproducible due to intra- and inter-observer variability. The software presently available is not suitable for this task. This article presents the OralImmunoAnalyser software (registered by the University of Santiago de Compostela-USC), which combines automatic image processing with a friendly graphical user interface that allows investigators to oversee and easily correct the automatically recognized cells before quantification. OralImmunoAnalyser is able to count the number of cells in three staining levels and each epithelial layer. Operating in the daily work of the Odontology Faculty, it registered a sensitivity of 64.4% and specificity of 93% for automatic cell detection, with an accuracy of 79.8% for cell classification. Although expert supervision is needed before quantification, OIA reduces the expert analysis time by 56.5% compared to manual counting, avoiding mistakes because the user can check the cells counted. Hence, the SUS questionnaire reported a mean score of 80.9, which means that the system was perceived from good to excellent. OralImmunoAnalyser is accurate, trustworthy, and easy to use in daily practice in biomedical labs. The software, for Windows and Linux, with the images used in this study, can be downloaded from https://citius.usc.es/transferencia/software/oralimmunoanalyser for research purposes upon acceptance.

Counselling toward reducing alcohol use, knowledge about its morbidity and personal consumption among students of medical and dental courses in north-western Spain

Background: Alcohol use disorder (AUD) is directly linked to high-risk consumption. Healthcare students have a crucial role to play in its prevention and management. The aim of this study is to analyse alcohol consumption, as well as to consider the knowledge and attitudes regarding morbidity, and the stage of change when providing assistance to quit AUD. Material and Methods: A cross-sectional study was conducted among Dentistry and Medical students using specific and validated questionnaires in an anonymous and voluntary way. Initially, 925 students were invited to participate, of them 500 were reached. Results: Among them 85.9% suffered from AUD of whom 75% were women (p<0.001), and it was considered that the female gender constituted an independent risk factor (OR=2.63, CI 95% 1.55-4.45, p<0.001). The majority of the participants did not achieve the pass mark, nonetheless, the results showed improved levels of knowledge among participants in the latter years of their studies (p<0.001). Dental students demonstrated greater shortcomings in terms of their knowledge of general pathology, whereas the medical students’ knowledge of oral pathologies proved worse (p<0.001). Most of students believed that identifying cases of AUD-affected patients falls within their competence, nonetheless, they believed that they do not have the necessary competencies. Among participants 58.2% were in a stage of change regarding AUD attitudes. Conclusions: The majority of respondents presented AUD. In general, the participants’ knowledge about alcohol was low. Reviewing the syllabuses and evaluating the implementation of gender-differentiated training programmes in both degrees would be considered necessary.(AU)

Association between xerostomia, oral and general health, and obesity in adults. A cross-sectional pilot study / Asociación entre xerostomía, salud bucal y general, y obesidad en adultos. Un estudio piloto transversal

Background: The objective of this study was to analyse the association between oral and general health variablesand obesity indicators with the sensation of dry mouth or xerostomia as evaluated on the Xerostomia Inventory(XI).Material and Methods: A total of 354 randomly selected subjects participated in this cross-sectional pilot studyand completed an anonymous questionnaire. Anthropometric, clinical, and xerostomic variables were evaluated.Kruskal-Wallis, ANOVA and Bonferroni test were used for multiple comparisons. ROC curves and multinomiallogistic regression were used to determine the (OR) risk of xerostomia.Results: A total of 30.7 % of respondents reported xerostomia based on XI. The dry mouth question, the XItaken as a “gold standard”, showed a diagnostic sensitivity of 70.37 %, and a specificity of 83.27 % (AUC=0.768,p<0.001). Logistical regression showed the highest xerostomia OR was associated to patients with bad self-per-ceived health, 6.31 (CI 95% 2.89-13.80, p<0.001). In the model adjusted for tooth mobility, bone or respiratorydiseases, and the consumption of anxiolytics and antidepressants, the OR was 3.46 (CI 95% 1.47-8.18, p=0.005).Conclusions: a high prevalence of xerostomia was found in this cross-sectional pilot study, which was significantlymore frequent in women, and increased with age. Xerostomia was associated to several systemic diseases, psycho-logical conditions, and oral functional disorders such as tooth mobility.These preliminary results can serve as the basis for developing guidelines for the application of innovative mea-sures designed to improve the quality of life of individuals with xerostomia.(AU)

Percepción de los estudiantes del grado de Odontología sobre la utilización de un sistema de respuesta interactiva (Kahoot) / Perception of students in dentistry degree on the use of an interactive response system (Kahoot)

Introducción: La adquisición de competencia clínica de diagnóstico en el alumnado de grado de Odontología debe potenciarse con metodologías docentes que le permitan realizar un aprendizaje continuo y autónomo de las materias clínicas. Objetivo: El objetivo del presente trabajo es analizar la percepción de los estudiantes sobre la utilización de la herramienta Kahoot® en la asignatura de Medicina Oral (tercer curso del grado) como estrategia educativa para el reconocimiento de lesiones orales mediante la realización de una encuesta de satisfacción sobre su uso. La herramienta Kahoot® permite a los docentes plantear cuestiones de respuesta múltiple o de verdadero-falso que los alumnos deben responder en un tiempo limitado a través de sus ordenadores personales, teléfonos móviles u otros dispositivos electrónicos conectados a la red wifi. Tras cada respuesta, la herramienta registra la opción correcta y los resultados obtenidos por cada alumno/a, así como su puntuación final y la global del grupo. Materiales y método: Empleamos Kahoot® en cinco de las unidades temáticas del programa durante las clases expositivas. Posteriormente, realizamos al alumnado un test de valoración mediante una escala de tipo Likert (1-5) para registrar la facilidad de utilización y la satisfacción de uso. Resultados: Los resultados obtenidos en los ítems facilidad de uso del sistema (4,31 ± 0,74), motivación (4,18 ± 0,75) y capacidad para aclarar conocimientos (4,13 ± 0,61) muestran una valoración positiva por el alumnado. Conclusiones: Esta metodología de aprendizaje a partir de juegos ha favorecido la enseñanza de conceptos teórico-prácticos y la adquisición de competencias transversales y específicas del grado de Odontología, además de fomentar la participación y el aprendizaje en el aula, lo que orienta al alumnado sobre los principales contenidos del programa y permite una evaluación interactiva de su rendimiento.(AU)

Introduction: The acquisition of clinical diagnostic competence in undergraduate Dentistry students must be enhanced with teaching methodologies that allow them to carry out continuous and autonomous learning of clinical subjects. Aim: The objective of this work is to analyze the students’ perception of the use of the Kahoot® tool in the subject of Oral Medicine (3rd year of the Degree) as an educational strategy for the recognition of oral lesions by conducting a satisfaction survey on its use. The Kahoot® tool allows teachers to pose multiple-answer, or true-false, questions that students must answer in a limited time through their personal computers, mobile phones, or other electronic devices connected to the wifi network. After each answer, the tool records the correct option and the results obtained by each student, as well as their final score and the overall score for the group. Materials and methods: We used Kahoot® in 5 of the thematic units of the program during the lectures/expositive classes. Subsequently, we performed an assessment test on the students using a Likert scale (1-5) to record ease of use and satisfaction with use. Results: The results obtained in the items ease of use of the system (4.31 ± 0.74), motivation (4.18 ± 0.75) and ability to clarify knowledge (4.13 ± 0.61) show the assessment positive by the students. Conclusions: This learning methodology based on games has favored the learning of theoretical-practical concepts and the acquisition of transversal and specific competences of the degree of Dentistry in addition to promoting participation and learning in the classroom, guiding the students on the main contents of the program allowing a interactive evaluation of student performance.(AU)

A new morphologic classification of the alveolar ridge after distraction osteogenesis in human patients. A 17 years retrospective case series study / Una nueva clasificación morfológica de la cresta alveolar después de la distracción osteogénesis en pacientes humanos. Un estudio de serie de casos retrospectivo de 17 años

Background: To perform a morphologic classification based on the results of bone augmentation after a distractionosteogenesis.Material and Methods: Thirty-four (34) patients (24 women and 10 men; mean age, 47.1 years (SD=9.5); age range,23 to 62 years) underwent a total of 42 alveolar ridge distractions before the placement of a total of 89 dentalimplants. Ridge bone morphology was evaluated as the main ordinal variable. Chi-squared, Kruskal-Wallis andANOVA one-way test were used.Results: Category I (30.95%): consisted of wide alveolar rim and no bone defects Category II (28.57%): widealveolar rim, lateral bone surface concavity. Category III (23.81%): narrow alveolar rim, lateral bone surface con-cavity. Category IV (2.38 %): distraction transport segment forming a bridge, without bone formed beneath andrequiring guided bone regeneration. Category V (9.52%): return of the transport segment to its initial position dueto the reverse rotation of the distractor screw. Category VI (4.76 %): distraction transport segment completely lost.Subcategory D (28.57%), consisted of lingual deviation of the distraction axis, occurring in any of the categories Ito IV. More men (76.9 %) presented with category I (p<0.001). The use of the chisel resulted mainly in categories I and II (69.4 %) (p<0.001). GBR was only required in 23.1 % of the cases in Category I (p=0.011). The bone heightachieved decreases as the category increases, due to the accompanying osteogenic limitations (p<0.001). The im-plants placed in category I were longer 11.5 ± 0.9 mm (CI95% 10.9-11.9 mm) compared to those placed in categoryIII with a length of 10.4 ± 1.5 mm (CI95% 9.5-11.4 mm) (p=0.035).Conclusions: The alveolar ridge after distraction osteogenesis could be divided into six morphologic categorieswhich provide a useful basis for decision-making regarding implant placement.(AU)

Therapeutic alternatives in the management of osteoradionecrosis of the jaws. Systematic review / Alternativas terapéuticas en el manejo de osteorradionecrosis de los maxilares. Revisión sistemática

Background: to systematically review the literature, comparing the healing of osteoradionecrosis (ORN) amongthe therapeutic alternatives: surgical, pharmacological and combined.Material and Methods: The review was organized according to the PRISMA protocol with regards to the fol-lowing PICO question: patients with ORN of the jaws (P=Patient); all interventions reported (I = intervention);between all therapies (C=Comparison); healing of lesions (O=outcome).Results: Surgical treatment was the most common choice (46.3%) followed by pharmacological treatment, exclu-sively (25.9%) or combined (26.9%). Treatment exclusively by surgical intervention seems to be most effectiveoption, with 51.2% of the lesions healed, OR for healing of 5.7 (CI95% 1.9-16.9, p=0.002). Only 1 case (0.9%) cor-responded to low level laser therapy.Conclusions: It seems clear that early intervention with conservative surgical combined with pharmacologicalmethods improves the prognosis of ORN.(AU)

Management options for low-dose methotrexate-induced oral ulcers: A systematic review

Background: Oral ulcers caused by methotrexate (MTX) at low doses are a known side effect of this drug. Although increasingly more patients are medicated with MTX, these painful ulcers, without traumatic origin and resistant to any type of treatment, are not usually identified by health professionals as a side effect of the medication. Material and Methods:In the absence of a consensus protocol for the effective treatment of oral lesions produced by MTX, the objective of this article was to review and analyse the information from articles related to oral ulcers produced by low-dose MTX and to record the clinical management performed and the MTX dose given to the patient. Data sources - Medline, Web of Science, and Cochrane Library. Participants - Patients treated with lowdose MTX (less than 25 mg/week). Interventions - Management of oral lesions caused by MTX. Study eligibility criterion, study appraisal and synthesis method: An initial search was carried out in the aforementioned databases with the terms ‘methotrexate AND oral OR ulcer’. The search was carried out using both medical subject heading (MeSH) terms and a free search between January 2003 and January 2018. Of the results obtained, two independent researchers analysed abstracts that met the search criteria, that is, those that mentioned oral ulcers produced by MTX at low doses. Next, both researchers read the complete article and determined whether it met the following inclusion criteria: written in English, specified the dose of MTX prescribed for the patient and specified the protocol of action for the ulcers. A third investigator acted as a mediator in cases of dispute. Agreement was calculated using Cohen’s kappa coefficient, with a k value of 0.82. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guide for systematic reviews was used. Results: The initial search resulted in a total of 66 articles, of which 30 were selected to assess their inclusion in this study. Finally, 16 met the inclusion criteria. Using the Pierson and Newcastle-Ottawa scales and Bradford Hill criteria modified for studies of case series and "in relation to a case", 2 were rated as high quality, 2 were rated as low quality and 12 were rated as medium quality. The limitations of this study are based on the fact that all of the articles available to carry out the systematic review were "in relation to a case or series of cases", with the heterogeneity of data that this implies. Conclusions: Evidence on the management of oral ulcers in the oral cavity produced by MTX at low doses is scarce due to the heterogeneity of data and the measures adopted in the selected studies. Therefore, it seems that this management is relegated to the perception of the clinician rather than to a specific protocol of action. Studies with a longer follow-up duration and larger sample size are needed to guide different health professionals on the management of these lesions

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Survival study of leukoplakia malignant transformation in a region of northern Spain

BACKGROUND: Oral leukoplakia is the most common potentially malignant disorder (PMD) of the oral cavity. The objectives of this study are to determine the clinicopathologic features in a group of patients with oral leukoplakia of Northern Spain (Galicia), determining the factors associated to clinical risk and analyzing the malignant transformation of these patients. MATERIAL AND METHODS: We included 85 patients. We recorded sex and age, habits like alcohol and tobacco, size, clinical appearance, site, number of lesions, and presence or absence of dysplasia. We assess the association between risk factors and transformation and developed a logistic regression analysis. Finally we used the Kaplan-Meier and log-rank test for the survival analysis. RESULTS: 7 patients (8.2%) had malignant transformation. The mean follow-up of the patients was 4.13 years versus 5.58 years of those who developed carcinoma. Only location and initial dysplasia have a statistically significant relationship with malignant transformation, but when applied the long rank test only the presence of dysplasia remains statistically significant (P<0,026). Oral Cancer Free Survival was 81.9% (0.150) at 11 years for the group without dysplasia. CONCLUSIONS: We found that the presence of dysplasia is the only risk factor that is statistically related to the development of a carcinoma

Applications of OralCDx ® methodology in the diagnosis of oral leukoplakia

Objective: We aim to evaluate the effectiveness of the brush biopsy technique using OralCDx ® (OralScan Laboratories Inc., Suffern, NY) as a new method for early diagnosis and control of a "potentially malignant disorder" such as oral leukoplakia. Design of the study: We performed a study in which samples were taken using OralCDx® on 24 patients who visited the Master of Oral Medicine, Oral Surgery and Implantology of the University of Santiago de Compostela between February 2009 and May 2010. These patients presented clinical and histological lesions that were consistent with oral leukoplakia. We evaluated the relationship between the keratinization degree of the lesions and cell representation; the diagnosis obtained through OralCDx ® and biopsies; and sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV). Results: 50% of patients were men and 50% women with an average age of 62.38 years. The Kappa coefficient relating keratinization of lesions and cell representation was 0.33, the OralCDx ® - biopsy diagnostic rate reached a Kappa value of 0.66, recording 72.7%, sensitivity and 92.3% specificity, PPV was 88.8%, while NPV reached 80%. Conclusions: cytology sampling with OralCDx ® showed high sensitivity and specificity values, which make it a good tool for monitoring oral leukoplakia, but nowadays the most reliable method that allows us to confirm the exact diagnosis of the lesions and their anatomical and pathological characteristics still is conventional biopsy using a surgical scalpel (AU)

Histopathological findings in oral lichen planus and their correlationwith the clinical manifestations

Objectives: To highlight the most characteristic histopathological findings of oral lichen planus and their correlationwith the clinical manifestations and forms.Study design: We performed a retrospective study of 50 biopsied and diagnosed cases of oral lichen planus obtainedover a period of 11 years, spanning from May 1998 to April 2009. We analyzed the age and sex of thepatient, type of lichen planus, location and different histopathological findings, comparing them with the clinicallesions.Results: Seventy eight percent of the patients are female and 22% are male, with an average age of 56.06 years forboth sexes. The most frequent clinical form is reticular, present in 78% of the cases, and the most common locationis the buccal mucosa, present in 70% of the patients. Hydropic degeneration of the basal layer and lymphocyticinfiltration in the subepithelial layer are observed in the entire sample. Signs of atypia were identified in 4% of thecases, but without dysplasic features. Other common histological findings were the presence of necrotic keratinocytes(92%), hyperplasia (54%), hyperkeratosis (66%), acanthosis (48%), and less frequently, serrated ridges (30%)and the presence plasma cells (26%) (AU)

Correlation between clinical and pathologic diagnosis in oral leukoplakia in 54 patients

The main aim of this study was to establish a correlation between the clinical and pathologic diagnosis of oralleukoplakia with a particular focus on epithelial dysplasia. We reviewed the medical records of 54 patients with a clinical and histologic diagnosis of oral leukoplakia who were seen at our center between 2002 and 2008. We found that the disease was more common in men (59.3%) than in women and we also detected a significantly greater prevalence of alcohol and tobacco consumption in men. The mean age of the patients was 62.57 years. Three patients had been histologically diagnosed with invasive cancer and 4 with carcinoma in situ. The most commonlesion site for leukoplakias with severe dysplasia and invasive carcinoma was the lateral aspect of the tongue, the floor of the mouth, and the gums. It is therefore essential to include these sites in the clinical examination to aidearly diagnosis. A higher degree of dysplasia should be suspected in non-homogeneous leukoplakias. While dysplasiais associated with a greater risk of malignant transformation, it is also important to monitor leukoplakias without dysplastic features as they can occasionally be the site of carcinoma (AU)

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Glositis romboidal: localización atípica. Caso clínico y diagnóstico diferencial / Rhomboid glossitis in atypical location: case report and differential diagnosis

La glositis romboidal media (GRM) es una alteración benigna, poco frecuente, que afecta ligeramente más a los varones. Suele localizarse en la línea media del dorso de la lengua por delante de la “V” lingual, en forma de área rojiza, romboidal, plana como una mácula o a veces exofítica, mamelonada, que puede sobresalir de 2 a 5 mm, en la que no se observan papilas filiformes.Se presenta el caso clínico de un varón de 61 años de edad que consulta por presentar una lesión exofítica asintomática en dorso de lengua, situada a nivel paramedial izquierdo. El estudio histopatológico es compatible con glositis romboidal. Se debe realizar el diagnóstico diferencial con otras lesiones exofíticas frecuentes en esta localización como: hemangioma o lesión vascular, granuloma piogénico, amiloidosis, tumor de células granulares y carcinoma de células escamosas, analizando tanto los aspectos clínicos como histopatológicos de cada una de ellas. A través de este caso clínico comprobamos que la GRM puede tener una localización paramedial, que denominamos atípica

Median rhomboid glossitis (MRG) is an uncommon benign abnormality of the tongue, most frequently affecting men. It is typically located around the midline of the dorsum of the tongue, anterior to the lingual “V”, appearing as a reddish, rhomboid area, depapillated, flat maculate or mamillated and raised by 2 - 5 mm. This paper reports a case of rhomboid glossitis in a 61-year-old man who consulted for a painless raised lesion on the dorsum of the tongue, in left paramedial (not medial) location. Histopathological findings were compatible with rhomboid glossitis. Other diagnoses considered but ruled out on the basis of the clinical and histopathological findings were haemangioma, pyogenic granuloma, amyloidosis, granular cell tumour, and squamous cell carcinoma. This case confirms that rhomboid glossitis may occur in paramedial locations

Distracción osteogénica del reborde alveolar: revisión de la literatura / Distraction osteogenesis of the alveolar ridge: a review of the literature

Uno de los principales problemas para la colocación de implantes dentales es la presencia de hueso insuficiente que impide que sean de una longitud y/o de un diámetro adecuados. Dentro de los métodos que se usan para el aumento del reborde alveolar se incluye tan solo desde hace una década la aplicación de los principios de distracción osteogénica (DO). Esta técnica se basa en la separación gradual de dos fragmentos de hueso perfectamente vascularizados, entre los que se forma un callo de distracción que progresivamente se transforma en hueso maduro. Un científico clave en el desarrollo de esta técnica fue el traumatólogo ruso Ilizarov. Esta revisión bibliográfica evalúa la metodología, el funcionamiento y las posibles aplicaciones de DO en el tratamiento de los defectos del reborde alveolar. Por sus cualidades demostradas, la DO podría sustituir el uso de injertos y regeneración ósea guiada para favorecer las relaciones esqueléticas de los rebordes alveolares (AU)

One of the principal problems in dental implantation is the lack of sufficient bone height or width. In the case of the alveolar ridge, a very effective technique for resolving this problem is distraction osteogenesis, introduced in this context about a decade ago. This technique is based on the gradual separation of a mobile but fully vascularized bone segment from the basal bone, leading to the formation of an intervening soft callus which gradually transforms to mature bone. A key researcher in the development of this technique was the Russian traumatologist Ilizarov. The present article reviews alveolar ridge distraction procedures and their clinical application. Alveolar ridge distraction may often be preferable to bone grafting or guided bone regeneration for increasing ridge height and width prior to implantation (AU)

Granuloma periférico de células gigantes. Revisión de 13 casos clínicos / Peripheral giant-cell granuloma. Review of 13 cases

El granuloma periférico de células gigantes es una lesión exofítica poco frecuente de la cavidad oral, también denominada épulis de células gigantes, osteoclastoma, granuloma reparativo de células gigantes, o hiperplasia de células gigantes. El motivo de este trabajo es presentar una serie de 13 pacientes, que acuden a la consulta de la Unidad Docente de Medicina Oral de la Facultad de Odontología de la Universidad de Santiago de Compostela. Valoramos la edad y el sexo de cada paciente, así como la localización, el tamaño, la evolución y el tratamiento de cada lesión, comparando los resultados obtenidos con los existentes en la literatura. El artículo presenta además una revisión de los procesos con los que debemos hacer diagnóstico diferencial, enfocando sobre todo tres de ellos –el tumor pardo del hiperparatiroidismo, el querubismo y el quiste óseo aneurismático- que tienen el mismo patrón histológico del granuloma periférico de células gigantes (AU)

Gingivoestomatitis herpética primaria en un paciente de 65 años / Primary herpetic gingivostomatitis in a 65-year-old patient

En este artículo presentamos un caso de gingivoestomatitis herpética primaria. Aparentemente se trata de una situación normal, pero en este caso el paciente en cuestión tiene 65 años, no siendo la edad normal de aparición de esta enfermedad, ya que ésta es más frecuente en niños de 1-5 años de edad, pudiendo aparecer en adolescentes y adultos jóvenes, siendo rara en niños menores de 6 meses y adultos mayores de 40 años. Así, en este trabajo describimos el caso clínico desde su comienzo, enfocando el diagnóstico y las diferentes enfermedades con las que hay que hacer diagnóstico diferencial (AU)

Lesiones inducidas por la aplicación tópica de cocaína / Lesions of the oral mucosa in cocaine users who apply the drug topically

El uso y abuso de cocaína es un fenómeno en continuo crecimiento en nuestra sociedad y cada vez se evidencian más los problemas relacionados con la utilización de esta droga. La cocaína puede ser utilizada de varias formas y sus efectos sobre la cavidad oral varían según la vía de administración. El objetivo de este artículo es presentar las lesiones, en cuatro pacientes, que surgen como consecuencia de la aplicación tópica de cocaína sobre la mucosa alveolar y nasal con la finalidad de aliviar el dolor producido por algias faciales, tipo cefaleas en racimos. Esa práctica ha producido lesiones eritematosas en tres de estos pacientes y rápida recesión gingival y secuestro óseo en otro de ellos. El potencial vasoconstrictor de la cocaína, asociado con el efecto cáustico de la droga sobre la mucosa, son probablemente los factores responsables de estas lesiones (AU)

Trismo y dolor tras la extracción de un tercer molar inferior. Efectos de despegar un colgajo mucoperióstico / Trismus and pain after removal of a lower third molar. Effects of raising a mucoperiosteal flap

Objetivo: Investigar el efecto de despegar un colgajo mucoperióstico sobre el trismo y el dolor después de la extracción de un tercer molar inferior. Diseño del estudio: Estudiamos una serie consecutiva de 218 pacientes, todos los cuales sufrieron la remoción de un tercer molar inferior impactado. De los 218 pacientes, 52 (grupo A) sufrieron extracciones simples sin despegar un colgajo mucoperióstico, 17 (grupo B) sufrieron extracciones despegando un colgajo mucoperióstico pero sin ostectomía, y 149 (grupo C) sufrieron la extracción despegando un colgajo mucoperióstico y practicando ostectomía. El trismo fue evaluado mediante la máxima apertura interincisal (MAI), determinada antes de la cirugía y 1 y 5 días después de la misma (MAIO, MAI1 y MAI5, respectivamente). El dolor fue evaluado en base al uso de analgésicos referido, igualmente 1 y 5 días después de la cirugía. Resultados: En el grupo A (sin colgajo) no había diferencias significativas entre MAIO y MAI5, aunque MAI1 era significativamente menor que MAI0. En los grupos B y C (colgajo) la diferencia entre MAI0 y MAI1 fue más marcada, y además MAI5 permaneció significativamente menor que MAI0. Ni MAI1 ni MAI5 variaron significativamente entre el grupo B (colgajo sin ostectomía) y el grupo C (colgajo con ostectomía). La proporción de sujetos del grupo A que refirieron el uso de analgésicos fue significativamente menor que las proporciones correspondientes a los grupos B y C en los días 1 y 5, y de nuevo no existían diferencias significativas entre estos dos grupos. Conclusiones: En extracciones de un tercer molar inferior, despegar un colgajo mucoperióstico aumenta significativamente el dolor y el trismo postquirúrgico. Estos efectos negativos no son agravados en sujetos que adicionalmente sufren ostectomía (AU)