RESUMO
The authors studied, with the Autobac machine, the kinetics of antibacterial activity of fosfomycin against Staphylococcus aureus, Streptococcus D' Streptococcus pneumoniae, Neisseria meningitidis, Acinetobactor lwoffi, Haemophilus influenzae, Salmonella typhimurium, Escherichia coli, Proteus rettgeri, Klebsiella pneumoniae, Serratia marcescens and Pseudomonas aeruginosa. A correlation appears between the kinetics of fosformycin antibacterial action and the microbial growth rate.
Assuntos
Antibacterianos/farmacologia , Bactérias/efeitos dos fármacos , Fosfomicina/farmacologia , Bactérias/crescimento & desenvolvimento , Cinética , Especificidade da EspécieRESUMO
A standard hand-washing technique was used in order to test the relative effectiveness of eight both detergent and alcoholic preparations intended to surgeon's hands disinfection. A single four or seven minutes washing with alcoholic solutions was shown to eliminate a much larger proportion of the skin flora than could be removed by a single four or seven minutes hand-washing with detergent antiseptic preparations. Authors have also determined effect of wearing surgical rubber gloves after skin disinfection and compared viable bacterial counts in hand washings immediately after the antiseptic treatment and when gloves had been worn for one hour.