RESUMO
Glomus tumors are benign soft tissue neoplasms that usually arise in the skin of the extremities; however, those tumors are sometimes located in other sites such as gastrointestinal (GIS), respiratory, and genital tracts. Gastrointestinal glomus tumors are mostly located in the gastric antrum. The most are small (<4 cm), but a few can be enormous. Herein, we report a case of a glomus tumor of the stomach in a 31-year-old female patient who presented with intermittent nausea, vomiting, hematemesis and melena for 2 months. On upper GIS endoscopy, submucosal lesion with ulceration was found in the prepyloric area. Partial gastrectomy including the lesion was performed. Immunohistochemical examination showed the glomus tumor. Since the glomus tumor is essentially benign and does not need a radical surgical procedure, the most important aspect of this tumor is its histologic identification and differentiation from more common gastric lesions, especially from malignant tumors.