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1.
J Pharm Bioallied Sci ; 14(Suppl 1): S522-S525, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-36110743

RESUMO

Background: In the root canal, the tenacity of microbial infection in either or both the periradicular area is the utmost communal source of endodontic failure. The majority of the gutta percha is removed using hand and rotational equipment. Aim of Study: To determine gutta percha removal by effectively utilizing three rotary instrumentation devices all through the endodontic retreatment. Objective of Study: To determine amongst the three Nickle-Titanium systems which one is significantly effective in retreatment along with comparison of retreatment efficiency using or avoiding the utilization of solvent. Materials and Methods: On 60 newly extracted, single-rooted mandibular premolars, every root canal was sealed using gutta percha and AH Plus sealer utilizing lateral compaction. After that, the samplings were separated into three investigational groups, each with 20 specimens. After that, individual groups were separated into ten specimens. After that, the groups were withdrawn with or without solvent. ProTaper retreatment files, Mtwo retreatment files, and R-Endo files were utilized to eradicate the gutta percha after two weeks. The extent of root canal filling material left in the coronal, middle, and apical thirds was recorded utilizing a stereomicroscope and a computer image processing program. The data was statistically examined using analysis of variance. Result: The ProTaper group exhibited a smaller amount of remnant filling material than the supplementary groups in the coronal and middle thirds; however a significant difference amid ProTaper and Mtwo, and Mtwo and R-Endo in the nonsolvent groups (P = 0.05) was concluded. In the nonsolvent group, the Mtwo group showed less leftover filling material. Conclusion: The elimination of root canal filling material was found to be equally effective in all systems. However, not a single experimental group could entirely eradicate gutta percha from the root canal.

2.
J Pharm Bioallied Sci ; 13(Suppl 1): S496-S500, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34447141

RESUMO

BACKGROUND AND OBJECTIVES: At present, none of the routinely used irrigating agents and activation techniques were able to completely remove the Ca(OH)2 intracanal medicament placed inside the root canal system during endodontic therapy. With this as the background, the aim of this study was to achieve complete removal of Ca(OH)2 when mixed with two different vehicles, using various irrigant activation techniques such as K-file, canal brush technique, and sonic irrigation technique, from the root canals of extracted human teeth. MATERIALS AND METHODS: Seventy-two mandibular premolar teeth with straight single root canal were selected and filled either with oil-based Metapex or calcium hydroxide powder mixed with distilled water and were activated using different activation techniques such as K-file, canal brush, and sonic MM1500 and NaOCl alone. Volumetric analysis was performed utilizing cone-beam computed tomography. RESULTS: None of the irrigants used were able to completely remove Ca(OH)2 from root canal. Sonic MM1500 showed significant removal efficacy than K-file, canal brush technique, and NaOCl for both aqueous-based and oil-based calcium hydroxide. CONCLUSION: Sonic MM1500 performed better than K-file, canal brush technique, and NaOCl in removing both Metapex and Ca(OH)2 powder. Regardless of the vehicles and agitation technique used, the remnants of Ca(OH)2 were present on all thirds of the canal walls.

3.
J Conserv Dent ; 22(1): 23-27, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30820078

RESUMO

BACKGROUND: In vivo angiogenesis is normal and vital process in growth and development, wound healing, and formation of granulation tissue wherein new blood vessels form from preexisting vessels as part of revascularization. Platelet-rich products promote wound healing associated with angiogenesis. Biomaterials such as titanium were found to be angiogenic. Unlike in vivo situations, in vitro angiogenesis, study cells, within a controlled environment. AIMS: The aim of this study is to evaluate the angiogenic potential of a novel platelet-rich product. MATERIALS AND METHODS: Blood was drawn from volunteers with informed consent. Blood samples were centrifuged to obtain platelet-rich products. Platelet concentrates prepared were platelet-rich plasma (PRP), platelet-rich fibrin, and a novel platelet-rich product which is titanium-prepared PRP (TPRP), obtained using titanium. The study which compared platelet concentrate was divided into four groups subjected to tissue culture. Phase-contrast microscope was used to determine the rate of growth by cell counting. STATISTICAL ANALYSIS: ANOVA was used for comparison within groups and post hoc for multiple comparisons. RESULTS: TPRP group showed granular ground substance. Group with platelet-rich fibrin (PRF) shows a high rate of growth whereas those with TPRP showed better growth rate when compared to its counterpart, PRP. CONCLUSIONS: This is the first study which introduces TPRP. Previous studies have proved that titanium-prepared PRF has better structural quality than its counterpart platelet-rich fibrin. This study concludes that TPRP has better angiogenic potential than its counterpart PRP. Further in vivo studies are needed to promote TPRP as a new generation of platelet products.

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