RESUMO
Acute acalculous cholecystitis (AAC) in association with acute Epstein-Barr virus (EBV) infection has rarely been described in childhood. In the literature, there are only four reported pediatric cases of AAC associated with isolated primary EBV infection. We present two cases (one new, one retrospectively reviewed) of children with Gilbert's syndrome (GS) who presented with AAC during the course of primary EBV infection. Antibiotics were not used and AAC subsided gradually as the infection regressed. The co-occurrence of GS might have played a contributory role in the pathogenesis of AAC during acute EBV infection.
Assuntos
Colecistite Acalculosa/diagnóstico por imagem , Infecções por Vírus Epstein-Barr/complicações , Doença de Gilbert/diagnóstico , Doença Aguda , Pré-Escolar , Feminino , Vesícula Biliar/diagnóstico por imagem , Humanos , Mononucleose Infecciosa/complicações , Masculino , UltrassonografiaRESUMO
The frequency of the (TA)7/(TA)7 promoter genotype of UDP-glucuronosyltransferase gene (UGT1A1) was significantly higher (p<0.05) in a group of 30 children with cholelithiasis than in a control group of 40 healthy children, indicating that this genotype might be an underlying factor for gallstone initiation in otherwise healthy children.
