Pilot trial protocol: community intervention to improve depressive symptoms among Peruvian older adults.

BACKGROUND: Non-pharmacological interventions have proven effective at alleviating depression and anxiety symptoms in older adults. Methodological refinement and testing of these interventions in new contexts are needed on a small scale before their effectiveness and implementation can be evaluated. The purpose of this pilot study is to assess the feasibility of a future large-scale trial comparing an adapted mental health multi-component evidence-based intervention (VIDACTIVA) versus standard care for older adults experiencing depression symptoms in urban, resource-limited settings in Lima, Peru. Furthermore, this study will explore the acceptability, feasibility, and fidelity of implementing the intervention. METHODS: We will conduct an open-label, mixed methods pilot feasibility study with two parallel groups. A total of 64 older adults, stratified by sex, will be randomized at a 1:1 ratio to either the "intervention" or "control." Participants will be followed for 22 weeks after enrollment. Those in the intervention group will receive eight VIDACTIVA sessions administered by community health workers (CHWs) over 14 weeks, with an additional eight weeks of follow-up. Participants in the control group will receive two psychoeducation sessions from a study fieldworker and will be directed to health care centers. Standard care does not involve CHWs. We will evaluate screening rates, recruitment strategies, retention rates, the acceptability of randomization, and assessments. Additionally, we will assess preliminary implementation outcomes-acceptability, feasibility, and fidelity-from the perspectives of CHWs (interventionists), older adults (main participants), older adults' relatives, and healthcare professionals. DISCUSSION: If the findings from this feasibility trial are favorable, a fully powered randomized controlled trial will be conducted to evaluate `both the effectiveness and implementation of the intervention. This research will make a substantial contribution to the field of mental health in older adults, particularly by emphasizing a meticulous examination and documentation of the implementation process. By doing so, this study will offer valuable methodologies and metrics for adapting and assessing mental health interventions tailored to the unique needs of older adults in resource-constrained contexts and diverse cultural settings. TRIAL REGISTRATION: The current trial registration number is NCT06065020, which was registered on 26th September 2023.

Agency and Mental Health Among Peruvian Older Adults During the COVID-19 Lockdown.

OBJECTIVES: To explore the experiences of older Peruvian adults living in urban areas of Lima under lockdown due to the National COVID-19 Emergency, this study analyzes how older adults (aged 60 and older) exercise agency while also living with the negative impacts of coronavirus disease 2019 (COVID-19) and related control measures. METHODS: Between August and December 2020, our research team conducted a telephone-based, qualitative study, in which we undertook semistructured interviews with a purposive sample of low-income older adults living with chronic multimorbidities and limited resources. Forty older adults, 24 women and 16 men, with a mean age of 72 years, participated in the study. For data analysis, we employed thematic analysis with a predominantly inductive approach. RESULTS: Older adults demonstrated several forms of agency to regulate emotions, maintain crucial bonds, foster social relationships, and seek economic and food security. Older adults experienced entertainment and support by caring for pets, undertaking farm work, and practicing their religious beliefs. For several participants and their families, quarantine was an opportunity to strengthen family relationships and learn new technologies. Older adults and their families reorganized themselves to assume new roles and perform activities that improved self-worth and confidence, thereby improving their well-being and mental health. DISCUSSION: Peruvian older adults exerted agency in different ways to respond to and sustain their mental health during the COVID-19 lockdown. Policymakers should value and recognize the agency of older adults when planning future health responses.

"We can't carry the weight of the whole world": illness experiences among Peruvian older adults with symptoms of depression and anxiety.

BACKGROUND: Despite the high levels of depression and anxiety symptoms in old age, the use of mental health services in this population is low. Help-seeking behaviors are shaped by how an individual perceives and experiences their illness. The objective of this study was to characterize the illness experiences of Peruvian older adults with depression and anxiety symptoms in order to lay the foundation for tailored community-based mental health interventions. METHODS: In this qualitative study, we conducted in-depth interviews with a purposively selected sample of older adults (≥ 60 years) from peri-urban areas of Lima, Peru. We included individuals with only depressive symptoms (Patient Health Questionnaire-9 ≥ 10), only anxiety symptoms (Beck Anxiety Inventory ≥ 16), with depressive and anxiety symptoms, and older adults who mentioned they had received mental health treatment/care. The interview guide included the following topics: perceptions and experiences about depression and anxiety; perceptions about the relationship between physical chronic diseases and mental health; experiences with mental health professionals and treatments, and coping mechanisms. Data collection was conducted between October 2018 and February 2019. RESULTS: We interviewed 38 participants (23 women, 15 men) with a mean age of 67.9 years. Participants' ideas and perceptions of depression and anxiety showed considerable overlap. Participants attributed depression and anxiety mainly to familial and financial problems, loneliness, loss of independence and past traumatic experiences. Coping strategies used by older adults included 'self-reflection and adaptation' to circumstances, 'do your part', and seeking 'emotional support' mainly from non-professionals (relatives, friends, acquaintances, and religion). CONCLUSIONS: Illness experiences of depression and anxiety set the pathway for tailored community-based mental health interventions for older adults. Overlapping narratives and perceptions of depression and anxiety suggest that these conditions should be addressed together. Mental health interventions should incorporate addressing areas related to depression and anxiety such as prevention of loss of independence, trauma, and loneliness. Good acceptability of receiving emotional support for non-professionals might offer an opportunity to incorporate them when delivering mental health care to older adults.

Patient-Centered Preference Assessment to Improve Satisfaction With Care Among Patients With Localized Prostate Cancer: A Randomized Controlled Trial.

PURPOSE: To study the effectiveness of the Patient Preferences for Prostate Cancer Care (PreProCare) intervention in improving the primary outcome of satisfaction with care and secondary outcomes of satisfaction with decision, decision regret, and treatment choice among patients with localized prostate cancer. METHODS: In this multicenter randomized controlled study, we randomly assigned patients with localized prostate cancer to the PreProCare intervention or usual care. Outcomes were satisfaction with care, satisfaction with decision, decision regret, and treatment choice. Assessments were performed at baseline and at 3, 6, 12, and 24 months, and were analyzed using repeated measures. We compared treatment choice across intervention groups by prostate cancer risk categories. RESULTS: Between January 2014 and March 2015, 743 patients with localized prostate cancer were recruited and randomly assigned to receive PreProCare (n = 372) or usual care (n = 371). For the general satisfaction subscale, improvement at 24 months from baseline was significantly different between groups (P < .001). For the intervention group, mean scores at 24 months improved by 0.44 (SE, 0.06; P < .001) from baseline. This improvement was 0.5 standard deviation, which was clinically significant. The proportion reporting satisfaction with decision and no regret increased over time and was higher for the intervention group, compared with the usual care group at 24 months (P < .05). Among low-risk patients, a higher proportion of the intervention group was receiving active surveillance, compared with the usual care group (P < .001). CONCLUSION: Our patient-centered PreProCare intervention improved satisfaction with care, satisfaction with decision, reduced regrets, and aligned treatment choice with risk category. The majority of our participants had a high income, with implications for generalizability. Additional studies can evaluate the effectiveness of PreProCare as a mechanism for improving clinical and patient-reported outcomes in different settings.

Depressive symptoms among adolescents and older adults in Mexico City.

PURPOSE: Determine the structure of depressive symptoms among adolescents and older adults through the person-centered approach of latent class analysis (LCA). METHODS: The study is based on data from two independent samples collected in Mexico City (2,444 adolescents and 2,223 older adults) which included the revised version of the CES-D. The presence or absence of depressed mood (dysphoria), diminished pleasure (anhedonia), drastic change in weight, sleep problems, thinking and concentration difficulties, excessive or inappropriate guilt, fatigue, psychomotor agitation/retardation, and suicide ideation were used in LCA to determine the structure of depressive symptoms for adolescents and older adults. RESULTS: Adolescents reported higher excessive or inappropriate guilt compared to older adults, while older adults had higher proportions of anhedonia, sleep problems, fatigue, and psychomotor agitation/retardation. Similar proportions were found in other symptoms. The LCA analysis showed the best fit with four latent classes (LC): LC 1, "symptoms suggestive of major depressive episode (MDE)" with prevalence of 5.9 % (n = 144) and 10.3 % (n = 230) among adolescents and older adults, respectively; LC 2, "probable MDE symptoms" 18.2 % (n = 446) and 23.0 % (n = 512); LC 3, "possible MDE" 27.7 % (n = 676) and 21.8 % (n = 485); LC 4, "without significant depressive symptoms" 48.2 % (n = 1,178) and 44.8 % (n = 996). The differences in item thresholds between the two groups (adolescents vs. older adults) were statistically significant (Wald test = 255.684, df = 1, p < 0.001). CONCLUSIONS: This study documented important similarities and differences in the structure of depressive symptoms between adolescents and older adults that merit acknowledgment, further study, and consideration of their potential clinical and public health implications.

Late-life depressive symptoms: prediction models of change.

BACKGROUND: Depression is a well-recognised problem in the elderly. The aim of this study was to determine the factors associated with predictors of change in depressive symptoms, both in subjects with and without baseline significant depressive symptoms. METHODS: Longitudinal study of community-dwelling elderly people (>60 years or older), baseline evaluations, and two additional evaluations were reported. Depressive symptoms were measured using a 30-item geriatric depression scale, and a score of 11 was used as cut-off point for significant depressive symptoms in order to stratify the analyses in two groups: with significant depressive symptoms and without significant depressive symptoms. Sociodemographic data, social support, anxiety, cognition, positive affect, control locus, activities of daily living, recent traumatic life events, physical activity, comorbidities, and quality of life were evaluated. Multi-level generalised estimating equation model was used to assess the impact on the trajectory of depressive symptoms. RESULTS: A number of 7882 subjects were assessed, with 29.42% attrition. At baseline assessment, mean age was 70.96 years, 61.15% were women. Trajectories of depressive symptoms had a decreasing trend. Stronger associations in those with significant depressive symptoms, were social support (OR.971, p<.001), chronic pain (OR 2.277, p<.001) and higher locus of control (OR.581, p<.001). In contrast for those without baseline significant depressive symptoms anxiety and a higher locus of control were the strongest associations. CONCLUSIONS: New insights into late-life depression are provided, with special emphasis in differentiated factors influencing the trajectory when stratifying regarding basal status of significant depressive symptoms. LIMITATIONS: The study has not included clinical evaluations and nutritional assessments.

Factors associated with help-seeking behaviors in Mexican older individuals with depressive symptoms: a cross-sectional study.

OBJECTIVE: Depression in the older individuals is associated with multiple adverse outcomes, such as high health service utilization rates, low pharmacological compliance, and synergistic interactions with other comorbidities. Moreover, the help-seeking process, which usually starts with the feeling "that something is wrong" and ends with appropriate medical care, is influenced by several factors. The aim of this study was to explore factors associated with the pathway of help seeking among older adults with depressive symptoms. METHODS: A cross-sectional study of 60-year or older community dwelling individuals belonging to the largest health and social security system in Mexico was carried out. A standardized interview explored the process of seeking health care in four dimensions: depressive symptoms, help seeking, help acquisition, and specialized mental health. RESULTS: A total of 2322 individuals were studied; from these, 67.14% (n = 1559) were women, and the mean age was 73.18 years (SD = 7.02); 57.9% had symptoms of depression; 337 (25.1%) participants sought help, and 271 (80.4%) received help; and 103 (38%) received specialized mental health care. In the stepwise model for not seeking help (χ(2) = 81.66, p < 0.0001), significant variables were female gender (odds ratio (OR) = 0.7, 95% confidence interval (CI) 0.511-0.958, p = 0.026), health-care use (OR 3.26, CI 95% 1.64-6.488, p = 0.001). Number of years in school, difficulty in activities, Short Anxiety Screening Test score, and indication that depression is not a disease belief were also significant. CONCLUSIONS: Appropriate mental health care is rather complex and is influenced by several factors. The main factors associated with help seeking were gender, education level, recent health service use, and the belief that depression is not a disease. Detection of subjects with these characteristics could improve care of the older individuals with depressive symptoms.

Frecuencia de los síntomas depresivos entre adultos mayores de la Ciudad de México / Frequency of depressive symptoms among older adults in Mexico City

Introduction Depression in the elderly is of interest because of its relationship with increased demand for health services, as well as the low frequency of diagnosis. Objective To determine the frequency of depressive symptoms (DS) among elderly beneficiaries in Mexico City by the revised scale of depression of the Center for Epidemiologic Studies of the United States (CES-DR) and the Yesavage Geriatric Depression Scale (GDS). Materials and methods In the first phase of the study we evaluated the presence of significant DS with the 30-item GDS. Those with scores of 11 or more were considered positive and were included in the second phase. In this phase were added a random sample with negative scores. All participants completed the second phase of the revised CES-DR. The 80 percentile was used in this study with a cut-off of 57 points. Results A total of 7449 elderly were included in the first phase. The prevalence of reported significant DS with the GDS was 21.7% (n = 1.616) (IC-95%, 20.4-23.0). The sample for the second phase included 2 923 elderly. The mean age was 70.8 years, 61.7% were women. Twelve percent (95% CI, 9.2-15.3) showed significant DS of major depression, 7.5% (95% CI, 6.3-8.9) was rated as probable, 17.2% (95% CI, 13.022.3) possible, 2.6% (95% CI, 2.2-3.1) sub-threshold depression episode and 60.7% (95% CI, 56.2-65.1) with no significant DS episodes of major depression. Significant frequency of major depression SD is presented using the GDS and CESDR was 6.5% (95% CI, 3.3-12.4). Conclusions The expression of the identified significant SD CES-DR is different from what is reported to the GDS. The CES-DR is more sensitive and specific to identify the presence of depressive symptoms.

Introducción La depresión en el anciano resulta de interés por su relación con el incremento de la demanda de servicios de salud, así como por su baja frecuencia de diagnóstico. Objetivo Determinar la frecuencia de los síntomas depresivos (SD) entre ancianos derechohabientes de la Ciudad de México, mediante la escala revisada de depresión del Centro de Estudios Epidemiológicos de los Estados Unidos (CES-DR) y la Escala de Depresión Geriátrica de Yesavage (GDS). Materiales y métodos En la primera fase del estudio se evaluó la presencia de SD significativos con la GDS de 30 ítems. Aquéllos con puntaje de 11 o más fueron considerados como positivos y se incluyeron en la segunda fase. En esta fase se agregó una muestra aleatoria con puntajes negativos. Todos los participantes en la segunda fase completaron la versión revisada del CES-DR. El percentil 80 se utilizó en este estudio con un punto de corte de 57 puntos. Resultados Un total de 7449 adultos mayores fueron incluidos en la primera fase. La prevalencia de SD significativos reportada con el GDS fue de 21.7% (n=1,616) (IC-95%, 20.4-23.0). La muestra para la segunda fase incluyó 2923 adultos mayores. La media de edad fue de 70.8 años, el 61.7% eran mujeres. El 12.0% (IC-95%, 9.2-15.3) presentó SD significativos de depresión mayor, 7.5% (IC-95%, 6.3-8.9) fue calificado como probable, 17.2% (IC-95%, 13.0-22.3) como posible, 2.6% (IC-95%, 2.2-3.1) con episodio de depresión sub-umbral y 60.7% (IC-95%, 56.265.1) sin SD significativos de episodios de depresión mayor. La frecuencia de SD significativos de depresión mayor que se presentó utilizando el GDS y el CESDR fue de 6.5% (IC-95%, 3.3-12.4). Conclusiones La expresión de SD significativos identificada con el CES-DR es diferente a lo que se reporta con el GDS. La CES-DR permite identificar la presencia de síntomas de depresión de manera más sensible y específica.

Enfocando la depresión como problema de salud pública en México / Targeting depression as a public health problem in Mexico

The present review aims at analyzing the magnitude and social impact of depression, as well as exploring models that help to understand the strategies needed to address this public health problem. The literature reveals that 9.2% of the general population has had a depressive episode and one in five persons will have an episode by age 75. Lower rates are observed in low and mid income in comparison to those with high income. These differences are not due to personal income, the probability of greater severity or delay in diagnosis, and are more likely related to cultural differences. Greater risk is observed among females, people younger than 60 years, marital status as single, widowed or divorced, and low educational attainment. The deleterious effect of depression on productivity is well established (27 days lost in the past year, on average, per case). The association with diabetes, hypertension, cardio vascular disease, drug use, suicide, and other risk behaviors has been frequently observed. Although unresolved questions remain about the presence or not of common risk factors and the chain of causality, it is a known fact that the combination of physical and mental disorders causes greater disability. With regard to the healthcare system, patients with depression and/or anxiety have higher utilization rates and healthcare costs, particularly among elderly patients. This healthcare overutilization is related with the low rates of diagnosis and adequate treatment of depression. About 26% of depression cases will not be diagnosed and, although a large proportion of patients have contact with healthcare services, nearly 30% never receive help for their depression. New treatment models that overcome barriers, understanding the sociocultural factors related with the problem, and addressing depression at the primary level of healthcare are urgent in Mexico.

El objetivo de la presente revisión es analizar la magnitud y el impacto social de la depresión, así como explorar modelos que permitan comprender mejor las estrategias necesarias para su atención. Los reportes revelan que 9.2% de la población general ha padecido un episodio de depresión, que una de cada cinco personas sufrirá uno antes de llegar a los 75 años y que los más jóvenes presentan tasas mayores. Tasas más bajas se observan en países de ingreso bajo y medio, en contraste con países de ingreso alto. Diferencias no relacionadas con la gravedad o el retraso en el diagnóstico probablemente se vinculen con diferencias culturales. Las mujeres, las personas sin pareja y el bajo nivel de educación se asocian con mayor riesgo. El efecto deletéreo en productividad (media de 27 días perdidos en el último año) es indiscutible. La asociación con diabetes, hipertensión y trastornos cardiacos, entre otras, ha sido frecuentemente investigada. Si bien no es clara la presencia o no de factores de riesgo comunes y la cadena de causalidad, la combinación de trastornos físicos y mentales genera más discapacidad. La depresión ha sido asociada a otras conductas como adicciones, suicidio y violencia, particularmente en jóvenes. En cuanto a los efectos en el sistema de salud, diversos estudios han demostrado que los pacientes con depresión tienen mayores tasas de utilización y mayores costos asociados, particularmente con ancianos. Esta sobreutilización está relacionada con la baja proporción de diagnóstico y tratamiento certero. El 26% de las personas no serán diagnosticadas y, a pesar de que una elevada proporción de pacientes contactaron con los servicios de salud, cerca del 30% nunca recibió ayuda. Nuevos modelos de atención que incluyan el abatimiento de las barreras, el entendimiento de los factores socioculturales y la inclusión del manejo primario de la depresión son urgentes.

Social networks and health-related quality of life: a population based study among older adults / Redes sociales y calidad de vida relacionada a la salud: un estudio de base poblacional en adultos mayores

OBJECTIVE: To examine the relationship between components of social networks and health-related quality of life (HRQL) in older adults with and without depressive symptoms. MATERIAL AND METHODS: Comparative cross-sectional study with data from the cohort study "Integral Study of Depression", carried out in Mexico City during 2004. The sample was selected through a multi-stage probability design. HRQL was measured with the SF-36. Geriatric Depression Scale (GDS) and the Short Anxiety Screening Test (SAST) determined depressive symptoms and anxiety. T-test and multiple linear regressions were conducted. RESULTS: Older adults with depressive symptoms had the lowest scores in all HRQL scales. A larger network of close relatives and friends was associated with better HRQL on several scales. Living alone did not significantly affect HRQL level, in either the study or comparison group. CONCLUSIONS: A positive association between some components of social networks and good HRQL exists even in older adults with depressive symptoms.

OBJETIVO: Examinar la relación entre componentes de redes sociales y calidad de vida relacionada con la salud (CVRS) de adultos mayores con o sin síntomas depresivos. MATERIAL Y MÉTODOS: Estudio transversal comparativo con datos de la cohorte "Estudio Integral de Depresión", realizado en la Ciudad de México en 2004. La muestra fue seleccionada por diseño probabilístico multietápico. La CVRS se midió con SF-36, mientras que Geriatric Depression Scale y Short Anxiety Screening Test determinaron síntomas de depresión y ansiedad. El análisis consistió de prueba T y regresiones lineales múltiples. RESULTADOS: Ancianos con síntomas de depresión reportaron puntuaciones más bajas en todas las escalas de CVRS; una red más grande de familiares y amigos se asoció con mejor CVRS en varias escalas. Vivir solo no afectó la CVRS en grupos de estudio y comparación. CONCLUSIONES: Existe una asociación positiva de algunos componentes de las redes sociales con la CVRS, incluso en ancianos con síntomas depresivos.

Social networks and health-related quality of life: a population based study among older adults.

OBJECTIVE: To examine the relationship between components of social networks and health-related quality of life (HRQL) in older adults with and without depressive symptoms. MATERIAL AND METHODS: Comparative cross-sectional study with data from the cohort study 'Integral Study of Depression', carried out in Mexico City during 2004. The sample was selected through a multi-stage probability design. HRQL was measured with the SF-36. Geriatric Depression Scale (GDS) and the Short Anxiety Screening Test (SAST) determined depressive symptoms and anxiety. T-test and multiple linear regressions were conducted. RESULTS: Older adults with depressive symptoms had the lowest scores in all HRQL scales. A larger network of close relatives and friends was associated with better HRQL on several scales. Living alone did not significantly affect HRQL level, in either the study or comparison group. CONCLUSIONS: A positive association between some components of social networks and good HRQL exists even in older adults with depressive symptoms.

Usefulness of two instruments in assessing depression among elderly Mexicans in population studies and for primary care / Utilidad de dos instrumentos para valorar depresión entre adultos mayores de México en estudios poblacionales y para la atención en el primer nivel de salud

OBJECTIVE: To determine the psychometric qualities of the CES-DR and GDS scales in the elderly and compare them to clinical psychiatric diagnoses. MATERIAL AND METHODS: The first phase consisted of home interviews for determining the psychometric qualities of the GDS and CES-DR scales. In the second phase, psychiatrists conducted diagnostic interviews. The sample consisted of 534 participants older than 60 years of age insured by the Mexican Institute of Social Security. RESULTS: First phase: Cronbach's alpha for the GDS was 0.87 and 0.86 for CES-DR. The GDS factorial analysis found eight factors that could explain 53.5 percent of the total variance and nine factors that explained 57.9 percent in the CES-DR. Second phase: Compared to the psychiatric diagnoses, CES-DR reported a sensitivity of 82 percent and a specificity of 49.2 percent; GDS reported 53.8 percent sensitivity and 78.9 percent specificity. CONCLUSIONS: CES-DR and GDS scales have high reliability and adequate validity but the CES-DR reports higher sensitivity.

RESUMEN OBJETIVO: Determinar las propiedades psicométricas de las escalas CES-DR y GDS para depresión en población anciana y compararlas con el diagnóstico clínico psiquiátrico. MATERIAL Y MÉTODOS: La primera fase consistió en entrevistas en casa para determinar las propiedades psicométricas. En la segunda fase, los psiquiatras condujeron entrevistas diagnósticas. La muestra consistió en 534 participantes de 60 años y más asegurados por el Instituto Mexicano del Seguro Social. RESULTADOS: Primera fase: Alfa de Cronbach para el GDS y CES-DR fue de 0.87 y 0.86, respectivamente. El análisis factorial del GDS reportó ocho factores que explicaron 53.5 por ciento de la varianza, comparado con nueve del CESDR que explicaron 57.9 por ciento. Segunda fase: Comparado con el diagnóstico psiquiátrico, el CES-DR reportó una sensibilidad de 82 por ciento y una especificidad de 49.2 por ciento comparado con 53.8 por ciento y 78.9 por ciento, respectivamente del GDS. CONCLUSIONES: Las escalas CES-DR y GDS tienen consistencia y adecuada validez pero el CES-DR reporta más alta sensibilidad.

Usefulness of two instruments in assessing depression among elderly Mexicans in population studies and for primary care.

OBJECTIVE: To determine the psychometric qualities of the CES-DR and GDS scales in the elderly and compare them to clinical psychiatric diagnoses. MATERIAL AND METHODS: The first phase consisted of home interviews for determining the psychometric qualities of the GDS and CES-DR scales. In the second phase, psychiatrists conducted diagnostic interviews. The sample consisted of 534 participants older than 60 years of age insured by the Mexican Institute of Social Security. RESULTS: First phase: Cronbach's alpha for the GDS was 0.87 and 0.86 for CES-DR. The GDS factorial analysis found eight factors that could explain 53.5% of the total variance and nine factors that explained 57.9% in the CES-DR. Second phase: Compared to the psychiatric diagnoses, CES-DR reported a sensitivity of 82% and a specificity of 49.2%; GDS reported 53.8% sensitivity and 78.9% specificity. CONCLUSIONS: CES-DR and GDS scales have high reliability and adequate validity but the CES-DR reports higher sensitivity.

Depressive symptoms among older adults in Mexico City.

BACKGROUND: Ageing and depression are associated with disability and have significant consequences for health systems in many other developing countries. Depression prevalence figures among the elderly are scarce in developing countries. OBJECTIVE: To estimate the prevalence of depressive symptoms and their cross-sectional association with selected covariates in a community sample of Mexico City older adults affiliated to the main healthcare provider. DESIGN: Cross-sectional, multistage community survey. PARTICIPANTS: A total of 7,449 persons aged 60 years and older. MEASUREMENTS: Depression was assessed using the 30-item Geriatric Depression Scale (GDS); cognitive impairment, using the Mini-Mental State Examination; and health-related quality of life with the SF-36 questionnaire. MAIN RESULTS: The prevalence of significant depressive symptoms was estimated to be 21.7%, and 25.3% in those aged 80 and older. After correcting for GDS sensitivity and specificity, major depression prevalence was estimated at 13.2%. Comparisons that follow are adjusted for age, sex, education and stressful life events. The prevalence of cognitive impairment was estimated to be 18.9% in depressed elderly and 13.7% in non-depressed. SF-36 overall scores were 48.0 in depressed participants and 68.2 in non-depressed (adjusted mean difference = -20.2, 95% CI = -21.3, -19.1). Compared to non-depressed elderly, the odds of healthcare utilization were higher among those depressed, both for any health problem (aOR 1.4, 95% CI = 1.1, 1.7) and for emotional problems (aOR 2.7, 95% CI = 2.2, 3.2). CONCLUSIONS: According to GDS estimates, one of every eight Mexican older adults had major depressive symptoms. Detection and management of older patients with depression should be a high priority in developing countries.

Depression in late life: A hidden public health problem for Mexico? / Depresión de la edad avanzada: ¿problema oculto de salud pública para México?

La depresión es una de las causas más importantes de discapacidad en el mundo, genera considerable sufrimiento a quienes la padecen, y los problemas asociados con ella son extremadamente costosos para la sociedad. La depresión es una de las enfermedades más debilitantes y más comunes entre los ancianos; sin embargo, generalmente es pasada por alto. El estudio epidemiológico más reciente en México estima que la prevalancia de episodios de depresión mayor es de 7.8 por ciento en la población de entre 18 y 54 años de edad, superada únicamante por la dependencia al alcohol (8.2 por ciento). Un estudio previo encontró que los adultos mayores tienden a presentar niveles de depresión más investigación acerca de factores de riesgo y protección para la depresión, ya que ello puede dar la pauta para establecer áreas de intervención. Atender la depresión entre las personas de edad avanzada puede contribuir significativamente a reducir costos de atención en salud, disminuir la discapacidad, la morbilidad y la mortalidad. Esto generaría importantes ahorros y liberaría recursos que podrían ser dedicados a la atención de otras necesidades de salud