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1.
Phys Rev Lett ; 123(24): 245101, 2019 Dec 13.
Artigo em Inglês | MEDLINE | ID: mdl-31922873

RESUMO

The first complete estimation of the compressible energy cascade rate |ϵ_{C}| at magnetohydrodynamic (MHD) and subion scales is obtained in Earth's magnetosheath using Magnetospheric MultiScale spacecraft data and an exact law derived recently for compressible Hall MHD turbulence. A multispacecraft technique is used to compute the velocity and magnetic gradients, and then all the correlation functions involved in the exact relation. It is shown that when the density fluctuations are relatively small, |ϵ_{C}| identifies well with its incompressible analog |ϵ_{I}| at MHD scales but becomes much larger than |ϵ_{I}| at subion scales. For larger density fluctuations, |ϵ_{C}| is larger than |ϵ_{I}| at every scale with a value significantly higher than for smaller density fluctuations. Our study reveals also that for both small and large density fluctuations, the nonflux terms remain always negligible with respect to the flux terms and that the major contribution to |ϵ_{C}| at subion scales comes from the compressible Hall flux.

2.
Phys Rev E ; 97(1-1): 013204, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29448457

RESUMO

We derive an exact law for three-dimensional (3D) homogeneous compressible isothermal Hall magnetohydrodynamic turbulence, without the assumption of isotropy. The Hall current is shown to introduce new flux and source terms that act at the small scales (comparable or smaller than the ion skin depth) to significantly impact the turbulence dynamics. The law provides an accurate means to estimate the energy cascade rate over a broad range of scales covering the magnetohydrodynamic inertial range and the sub-ion dispersive range in 3D numerical simulations and in in situ spacecraft observations of compressible turbulence. This work is particularly relevant to astrophysical flows in which small-scale density fluctuations cannot be ignored such as the solar wind, planetary magnetospheres, and the interstellar medium.

3.
Phys Rev Lett ; 120(5): 055102, 2018 Feb 02.
Artigo em Inglês | MEDLINE | ID: mdl-29481187

RESUMO

The first estimation of the energy cascade rate |ε_{C}| of magnetosheath turbulence is obtained using the Cluster and THEMIS spacecraft data and an exact law of compressible isothermal magnetohydrodynamics turbulence. The mean value of |ε_{C}| is found to be close to 10^{-13} J m^{-3} s^{-1}, at least 2 orders of magnitude larger than its value in the solar wind (∼10^{-16} J m^{-3} s^{-1} in the fast wind). Two types of turbulence are evidenced and shown to be dominated either by incompressible Alfvénic or compressible magnetosoniclike fluctuations. Density fluctuations are shown to amplify the cascade rate and its spatial anisotropy in comparison with incompressible Alfvénic turbulence. Furthermore, for compressible magnetosonic fluctuations, large cascade rates are found to lie mostly near the linear kinetic instability of the mirror mode. New empirical power-laws relating |ε_{C}| to the turbulent Mach number and to the internal energy are evidenced. These new findings have potential applications in distant astrophysical plasmas that are not accessible to in situ measurements.

4.
J Prev Alzheimers Dis ; 4(3): 183-193, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29182709

RESUMO

OBJECTIVE: The aims of the Research Of biomarkers in Alzheimer's diseaSe (ROSAS) study were to determine the biofluid and imaging biomarkers permitting an early diagnosis of Alzheimer's disease and better characterisation of cognitive and behavioural course of the pathology. This paper outlines the overall strategy, methodology of the study, baseline characteristics of the population and first longitudinal results from the ROSAS cohort. METHODS: Longitudinal prospective monocentric observational study performed at the Alzheimer's disease Research centre in Toulouse. A total of 387 patients were studied and analyzed in 3 groups: 184 patients with dementia of Alzheimer's type, 96 patients with memory disorders without dementia (Mild Cognitive Impairment) and 107 patients without abnormal memory tests (control group), and were followed up during 4 years. Patient's sociodemographic characteristics, risk factors, medical conditions, previous and current medications, neuropsychological assessment and overall cognitive status were recorded. Blood and urine samples were collected at every year, Magnetic Resonance Imaging were performed at inclusion, after one year of follow-up and at the end of the study. RESULTS: At baseline, three different groups of the cohort differed interestingly in age, level of education, and in percentage of ApoEε4 carriers whereas the history of cardiovascular and endocrine pathologies were similar among the groups. During the follow-up period (3-4 years) 42 mild cognitive impairment patients (43.8%) progressed to dementia, 7 controls progressed into mild cognitive impairment and 1 patient in the control group converted from mild cognitive impairment group to dementia of Alzheimer's type group. During the first year of follow up, the incidence of progression from mild cognitive impairment to dementia of Alzheimer's type was 12.7 per 100, during the second year 33.9 per 100 and 46.7 per 100 for the third year. CONCLUSION: This paper presents the baseline characteristics of the unique French prospective monocenter study in which the natural course of dementia of Alzheimer's type was evaluated. Future analysis of blood and urine samples collection from the ROSAS study will permit to identify possible biofluid biomarkers predicting the early stages of the dementia of Alzheimer's type and risk of progression from Mild Cognitive Impairment to Alzheimer's disease.


Assuntos
Doença de Alzheimer/diagnóstico , Doença de Alzheimer/genética , Apolipoproteína E4/genética , Biomarcadores/sangue , Biomarcadores/urina , Transtornos Cognitivos/diagnóstico , Transtornos Cognitivos/genética , Progressão da Doença , Diagnóstico Precoce , Seguimentos , França , Humanos , Estudos Longitudinais , Imageamento por Ressonância Magnética , Testes Neuropsicológicos , Estudos Prospectivos , Projetos de Pesquisa
5.
Phys Rev Lett ; 117(17): 173201, 2016 Oct 21.
Artigo em Inglês | MEDLINE | ID: mdl-27824468

RESUMO

High-precision spectroscopy in systems such as molecular hydrogen and helium ions is very interesting in view of tests of quantum electrodynamics and the proton radius puzzle. However, the required deep ultraviolet and shorter wavelengths pose serious experimental challenges. Here we show Ramsey-comb spectroscopy in the deep ultraviolet for the first time, thereby demonstrating its enabling capabilities for precision spectroscopy at short wavelengths. We excite ^{84}Kr in an atomic beam on the two-photon 4p^{6}→4p^{5}5p[1/2]_{0} transition at 212.55 nm. It is shown that the ac-Stark shift is effectively eliminated, and combined with a counterpropagating excitation geometry to suppress Doppler effects, a transition frequency of 2 820 833 101 679(103) kHz is found. The uncertainty of our measurement is 34 times smaller than the best previous measurement, and only limited by the 27 ns lifetime of the excited state.

6.
Phys Rev E ; 94(6-1): 063206, 2016 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28085374

RESUMO

We derive exact scaling laws for a three-dimensional incompressible helical two-fluid plasma, without the assumption of isotropy. For each ideal invariant of the two-fluid model, i.e., the total energy, the electron helicity, and the proton helicity, we derive simple scaling laws in terms of two-point increment correlation functions expressed in terms of the velocity field of each species and the magnetic field. These variables are appropriate for comparison with direct numerical simulation data and with in situ measurements in the near-Earth space over a broad range of spatial scales. Finally, using the exact scaling laws and dimensional analysis we predict the magnetic energy and electron helicity spectra for different ranges of scales.

7.
J Chem Phys ; 136(22): 224310, 2012 Jun 14.
Artigo em Inglês | MEDLINE | ID: mdl-22713050

RESUMO

Potential energy and permanent dipole moment surfaces of the electronic ground state of formyl negative ion HCO(-) are determined for a large number of geometries using the coupled-cluster theory with single and double and perturbative treatment of triple excitations ab initio method with a large basis set. The obtained data are used to construct interpolated surfaces, which are extended analytically to the region of large separations between CO and H(-) with the multipole expansion approach. We have calculated the energy of the lowest rovibrational levels of HCO(-) that should guide the spectroscopic characterization of HCO(-) in laboratory experiments. The study can also help to detect HCO(-) in the cold and dense regions of the interstellar medium where the anion could be formed through the association of abundant CO with still unobserved H(-).

8.
Phys Rev E Stat Nonlin Soft Matter Phys ; 76(5 Pt 2): 056313, 2007 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-18233762

RESUMO

We investigate the locality or nonlocality of the energy transfer and the spectral interactions involved in the cascade for decaying magnetohydrodynamic (MHD) flows in the presence of a uniform magnetic field B at various intensities. The results are based on a detailed analysis of three-dimensional numerical flows at moderate Reynolds numbers. The energy transfer functions, as well as the global and partial fluxes, are examined by means of different geometrical wave number shells. On the one hand, the transfer functions of the two conserved Elsässer energies E+ and E- are found local in both the directions parallel (k|| direction) and perpendicular (kperpendicular direction) to the magnetic guide field, whatever the B strength. On the other hand, from the flux analysis, the interactions between the two counterpropagating Elsässer waves become nonlocal. Indeed, as the B intensity is increased, local interactions are strongly decreased and the interactions with small k|| modes dominate the cascade. Most of the energy flux in the kperpendicular direction is due to modes in the plane at k||=0, while the weaker cascade in the k|| direction is due to the modes with k||=1. The stronger magnetized flows tend thus to get closer to the weak turbulence limit, where three-wave resonant interactions are dominant. Hence, the transition from the strong to the weak turbulence regime occurs by reducing the number of effective modes in the energy cascade.

9.
Phys Rev E Stat Nonlin Soft Matter Phys ; 63(1 Pt 2): 016408, 2001 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-11304366

RESUMO

We develop a WKB approach to the rapid distortion theory for magnetohydrodynamic turbulence with large magnetic Prandtl number. Within this theory, we study the growth of small-scale magnetic fluctuations in a large-scale velocity field being initially a pure strain. We show that the magnetic Lorentz force excites a secondary flow in the form of counterrotating vortices on the periphery of the magnetic spot. Those vortices slow down stretching of the magnetic spot and thus provide a negative feedback for a small-scale magnetic dynamo.

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