Safety and effectiveness of cantharidin-podophylotoxin-salicylic acid in the treatment of recalcitrant plantar warts.

The aim of our study was to evaluate the efficacy and safety of topical cantharidin-podophylotoxin-salicylic acid (CPS) treatment of recalcitrant plantar warts (RPW). This study was carried out in a health center in the city of A Coruña (Spain) between January and December 2013. A total of 75 patients completed all the stages of the research process. Information related to treatment with CPS and adverse effects was abstracted from medical records. Of 93 potential patients identified, 75 had at least one follow-up visit or telephone call after treatment and were included in this study. Patients experienced an average of 5.4 visits until complete resolution of their plantar wart occurred, although CPS was not applied at every visit. Fifty-four patients required one application to eliminate the wart and 21 patients required two applications/patient. Seventy-seven percent of patients experienced blistering - an expected therapeutic side effect. All patients experienced some form of an adverse event, the most common being pain (81.3%) and significant blistering (15%). Other side effects were rare (18.7%) and included pruritus, possible mild infection, significant irritation, and bleeding. All patients reported treatment, supporting our results that CPS is a safe and efficacious treatment modality for RPW and should be considered when symptomatic infection necessitates treatment.

[Determination of plantar pressure in people who use orthoses of the foot]. / Determinación de la presión plantar en personas que utilizan ortesis a medida en el pie.

OBJECTIVE: To know the transfer of static plantar pressures and body weight distribution through the lower limbs that occur in people with and without the use of orthoses of different densities and influence in other areas of the foot. MATERIAL AND METHODS: 32 people participated through non-probability convenience sampling in a quasi-experimental study in which self-reported data were recorded, the determination of plantar pressure, and body weight distribution. RESULTS: 64 feet were studied, showing no difference between the medium pressure and the forefoot without orthoses of 5 mm and 10 mm. Decrease in average pressure and percentage of body weight, both statistically significant, with hindfoot orthoses 10 mm was observed. CONCLUSIONS: Given the current evidence for the prescribing and use of foot orthoses is limited, designed to improve the functionality and prevent the onset of disease and foot deformities, these results highlight the need to prescribe orthotics 10 mm when needed to relieve pressure on the backfoot, not seeing the average pressure increased nor diminished in other areas of the foot.