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4.
Europace ; 17(10): 1533-40, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25935163

RESUMO

AIMS: Left atrial appendage (LAA) is the source of thrombi in up to 90% of patients with non-valvular atrial fibrillation (AF). Catheter ablation (CA) is an effective treatment for symptomatic AF and, in selected cases, LAA occlusion devices have been introduced as an alternative to oral anticoagulants (OACs). The safety and feasibility of combining CA and percutaneous LAA closure (LAAC) are unknown. METHODS AND RESULTS: Patients with symptomatic drug-refractory AF, CHADS2 score of ≥1, and CHA2DS2-VASc score ≥2 were included. Catheter ablation consisted in pulmonary vein isolation with or without roof line with radiofrequency and LAA was occluded with the Watchman or Amplatzer Cardiac Plug (ACP) devices guided by angiography and transoesophageal echocardiography. A total of 35 patients were included (71% male; 70 years). Median score was 3 on both CHA2DS2-VASc and HAS-BLED, 9% had prior stroke under OAC, and 48% had bleeding complications. Successful CA and device implantation were achieved in 97% of cases. The Watchman device was used in 29 patients and ACP in 6 patients. Periprocedural complications included three cases of cardiac tamponade. At 3 months, all patients met the criteria for successful sealing of the LAA. After a mean follow-up of 13 months (3-75), 78% of patients were free of arrhythmia recurrences and OAC was withheld in 97% of patients. CONCLUSIONS: The combination of CA and percutaneous LAAC in a single procedure is technically feasible in patients with symptomatic drug-refractory AF, high risk of stroke, and contraindications to OACs, although it is associated with a significant risk of major complications.


Assuntos
Apêndice Atrial/cirurgia , Fibrilação Atrial/cirurgia , Ablação por Cateter , Veias Pulmonares/cirurgia , Dispositivo para Oclusão Septal , Idoso , Anticoagulantes/uso terapêutico , Ecocardiografia Transesofagiana , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
5.
Arch Cardiol Mex ; 82(3): 235-42, 2012.
Artigo em Espanhol | MEDLINE | ID: mdl-23021361

RESUMO

The present document reviews various aspects of the current status of cardiac resynchronization therapy: mechanisms of action, current indications and implantation technique.


Assuntos
Terapia de Ressincronização Cardíaca , Desfibriladores Implantáveis , Humanos , Seleção de Pacientes , Implantação de Prótese/métodos
6.
Arch. cardiol. Méx ; 82(3): 235-242, jul.-sept. 2012. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-685338

RESUMO

Se revisa el estado actual de la terapia de resincronización cardiaca en sus diferentes aspectos: mecanismos de acción, indicaciones actuales y técnica de implante.


The present document reviews various aspects of the current status of cardiac resynchronization therapy: mechanisms of action, current indications and implantation technique.


Assuntos
Humanos , Terapia de Ressincronização Cardíaca , Desfibriladores Implantáveis , Seleção de Pacientes , Implantação de Prótese/métodos
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