[Pyogenic brain abscesses: experience with 60 consecutive cases]. / Abscesos piógenos encefálicos. Nuestra experiencia en 60 casos consecutivos.

INTRODUCTION: Brain abscess is a focal suppurative process in the brain parenchyma that still carries high mortality rates. Outcome is closely related with a correct and early management. In order to evaluate this management we have reviewed the brain abscesses treated in our Department during the last 14 years. MATERIAL AND METHODS: The authors present a retrospective series of 60 consecutive patients with pyogenic brain abscess treated between January of 1990 and February of 2004 paying attention to the epidemiology, etiology, clinical data, microbiology, treatment modalities and outcome. RESULTS: The male to female rate was 5.6 to 1. The average age was 47 years. Hematogenous spread was most frequent, followed by contiguous spread. In 22% of the cases, the origin was unknown. Regarding the causative pathogens, Gram positive cocci are the most frequent (44%), with a 40% incidence of anaerobics. A mixed infection occurred in 39% of the abscesses. Three modalities of treatment were used: non surgical, catheter drainage-aspiration and surgical excision. Outcome was excellent in 52 patients (86.7%) and 4 patients (6.7%) died. Although outcome was similar in both surgical modalities, drainage-aspiration required a second procedure in 20% of the cases while this was necessary in only 10% of the patients with abscess excision. Length of admission was shorter in the drainage-aspiration group than in the excision group (13 and 26 days respectively). Mortality was higher in patients with low level of consciousness and age over 70 years. CONCLUSIONS: The shorter admission time associated with drainage-aspiration of brain abscesses together with its high efficacy and low morbidity suggests that drainage-aspiration should be used as the first mode of treatment.

Abscesos piógenos encefálicos. Nuestra experiencia en 60 casos consecutivos / Pyogenic brain abscesses: experience with 60 consecutive cases

Introducción. El absceso cerebral es un proceso supurativo focal en el parénquima cerebral que todavía presenta una elevada mortalidad. El resultado está altamente relacionado con un tratamiento precoz y adecuado. Para valorar dicho tratamiento revisamos los abscesos cerebral es tratados en nuestro Servicio en los últimos 14 años. Material y métodos. Presentamos una revisión de los60 pacientes con diagnóstico de absceso cerebral piógeno tratados en el Servicio de Neurocirugía del Hospital Infanta Cristina entre Enero de 1990 y Febrero de 2004, prestando atención a la epidemiología, clínica, etiología, microbiología, tratamiento y resultado final. Resultados. La relación hombre/mujer es 5.6/1, con una edad media de 47 años; el origen de la infección más frecuente es el hematógeno, seguido de las infecciones contiguas, con un 22% de abscesos de origen desconocido; los gérmenes más frecuentes son los cocos Gram positivos (44%), con una importante presencia de gérmenes anaerobios (40%); en un 39% de los casos las infecciones son mixtas; las modalidades de tratamiento fueron la punción de los abscesos para aspiración-drenaje, la cirugía abierta, con o sin resección capsular, y el tratamiento médico exclusivo. 52 pacientes (86.7 %)curaron sin secuelas y 4 (6,7 %) fallecieron. Aunque los resultados de ambos tipos de tratamiento quirúrgico son similares, el drenaje del absceso requirió en un 20%de los casos un segundo proceder quirúrgico, mientras que la craneotomía lo precisó sólo en el 10%; la estancia media en nuestro hospital fue mucho menor en los abscesos tratados mediante drenaje que en los tratados mediante cirugía abierta (13 vs 26 días); la mortalidad fue mayor en pacientes con bajo nivel de conciencia al ingreso y en mayores de 70 años. Conclusiones. Consideramos que la menor estancia media del drenaje del absceso, unido a su alta eficacia y su baja morbilidad, hacen aconsejable su uso como tratamiento de primera elección

Introduction. Brain abscess is a focal suppurative process in the brain parenchyma that still carries high mortality rates. Outcome is closely related with a correct and early management. In order to evaluate this management we have reviewed the brain abscesses treated in our Department during the last 14 years. Material and Methods. The authors present a retrospective series of 60 consecutive patients with pyogenic brain abscess treated between January of 1990 and February of 2004 paying attention to the epidemiology, etiology, clinical data, microbiology, treatment modalities and outcome Results. The male to female rate was 5.6 to 1. The average age was 47 years. Hematogenous spread was most frequent, followed by contiguous spread. In 22%of the cases, the origin was unknown. Regarding the causative pathogens, Gram positive cocci are the most frequent (44%), with a 40% incidence of an aerobics. A mixed infection occurred in 39% of the abscesses. Three modalities of treatment were used: non surgical,catheter drainage-aspiration and surgical excision. Outcome was excellent in 52 patients (86.7%) and 4patients (6.7%) died. Although outcome was similar in both surgical modalities, drainage-aspiration required a second procedure in 20% of the cases while this was necessary in only 10% of the patients with abscess excision. Length of admission was shorter in the drainage aspiration group than in the excision group (13 and 26 days respectively). Mortality was higher in patients with low level of consciousness and age over 70 years. Conclusions. The shorter admission time associated with drainage-aspiration of brain abscesses together with its high efficacy and low morbidity suggests that drainage aspiration should be used as the first mode of treatment

Brucellar spinal epidural abscesses. Analysis of eleven cases.

Brucellar spinal epidural abscesses (BSEA) are rare and very few series of them have been reported. In order to evaluate the clinical characteristics, management and outcome of this entity, the clinical records and current status of a series of 11 patients have been retrospectively reviewed. A series of 11 patients treated for BSEA in our Service during a period of 12 years (1989-2000) have been retrospectively studied. Spinal epidural abscesses (SEA) were diagnosed by MRI, CT or at surgery. Brucellar aetiology of SEA was considered when seroagglutination tests were positive at a titre of 1/160 or higher, and/or Brucella spp. were isolated in the blood or sample cultures. Ten of the 11 cases were treated with rifampicin plus doxycycline and in the remaining patient streptomycin was added because of a poor initial response. Six patients underwent surgical decompression and debridement of the SEA. Outcome was excellent in nine cases and good in two. There was no mortality and only one patient recovered incompletely from preadmission neurological deficits. Although BSEA is considered to be an unusual complication of spondylitis, our findings show that in some cases it can follow direct haematogenous spread to the extradural space. Surgical treatment must be undertaken when major neurological deficits are present. If antibiotic treatment is chosen as the initial therapy, the possibility of sudden neurological deterioration must be taken into account. Contrary to the high morbi-mortality rates reported in pyogenic or tuberculous SEA, BSEA has a good prognosis with early diagnosis and appropriate management.

[Anterior cervical interbody fusion with treathed cylindrical bone versus bak-cace: a comparative study]. / Estudio camparativo de la artrodesis cervical con injerto óseo roscado e implante de titanio.

The authors conducted a prospective and randomized study in 44 consecutive patients requiring cervical interbody fusion following anterior cervical discectomy to compare the efficacy of heterologous threaded cylindrical bone (Unilab Surgibone) versus titanium implant (Bak-C; Spine-Tech, Minneapolis ). The patients were evaluated between two and five years postoperatively and the objectives of the study were to assess the potential differences in implant shifting, interespace collapse, angulation, maintenance of cervical alignment and lordosis, and clinical and radiographic fusion success rates between the two fusion substrates. Clinical results were satisfactory with both types of implant. However the threaded cylindrical titanium implant was found to be superior to the heterologous threaded cylindrical bone as an interbody substrate after single -and multiple- level anterior cervical decompression procedures with respect to maintenance of cervical interspace height, interspace angulation and radiographic fusion success rates.

[Carpal tunnel syndrome? Case report]. / ¿Síndrome del tunel carpiano? Case report.

A patient with an initial misdiagnosis of carpal tunnel syndrome is presented. The clinical manifestations were suggestive of such diagnosis, but there were some anamnesis and exploratory aspects requiring to establish a differential diagnosis. Painful syndrome was caused by a brachial plexus compression at the costoclavicular region due to a subclavicular hematoma in a patient under anticoagulant treatment. Carpal tunnel pathology is a frequent cause of neuropathy, however others diagnosis should be ruled out as shown in the present case.

¿Síndrome del tunel carpiano? Case report / ¿Carpal tunnel syndrome? Case report

Presentamos el caso de una paciente diagnosticada erróneamente de un síndrome del túnel carpiano. Las manifestaciones clínicas fueron sugestivas de dicho diagnóstico, pero con unas particularidades anamnésicas y exploratorias que merecen comentarios al hacer un diagnóstico diferencial. El origen del síndrome doloroso se debía a la existencia de un hematoma de localización subclavicular en una paciente en tratamiento con anticoagulantes y que originaba una compresión del plexo braquial a nivel del desfiladero costoclavicular. Consideramos de interés práctico este caso que aportamos, por cuanto la patología del túnel carpiano es una de las neuropatías por atrapamiento nervioso más frecuentes en la clínica diaria y debe de hacernos pensar en otros posibles diagnósticos que aquí revisamos (AU)

Delayed pneumocephalus in shunted patients. Report of three cases and review of the literature.

Delayed pneumocephalus is a very rare complication of CSF shunt systems with only 37 cases so far reported. We report three additional cases with different mechanisms of production, clinical presentations and managements. While the first patient was treated with closure of the site of air entrance and shunt externalization, in the second case, modification of the shunt was enough to solve the pneumocephalus, even when a skull base fistula was suspected. The third one died during treatment from complications. The literature is reviewed with respect to the aetiology, clinical presentation, radiological findings and management of this problem.

Inadvertent intraspinal placement of a Foley catheter in severe craniofacial injury with associated atlanto-occipital dislocation: case report.

A case of fatal, inadvertent, intraspinal placement of a Foley urinary catheter is presented. The patient suffered a severe craniofacial injury with life-threatening epistaxis requiring emergent tamponade with two Foley catheters plus gauze packing. There was an associated atlanto-occipital dislocation. The mechanism of production is discussed, and guidelines to avoid this complication are outlined.

Focal dystonia secondary to cavernous angioma of the basal ganglia: case report and review of the literature.

The case of a young woman with focal dystonia of the hand due to a cavernous angioma of the basal ganglia is presented. The lesion involved the anterior third of the lentiform nucleus and a large portion of white matter anterior to this nucleus and lateral to the head of the caudate, as shown by magnetic resonance imaging; it was completely removed through a computed tomography-assisted stereotactic craniotomy by microsurgical technique, resulting in the cure of the patient. These facts support the pathophysiological hypothesis of a disruption of the striatopallidothalamic projection to the premotor cortex as the cause of symptomatic dystonia. A review of the reported cases of cavernous angiomas of the deep cerebral gray nuclei shows that this is the first case of cavernous angioma associated with movement disorder.