The histopathology of the humeral head in glenohumeral osteoarthritis.

Objective: The histopathologic wear patterns in glenohumeral osteoarthritis (GOA) have not been described. The aims of the study were to a) describe the histopathology of humeral head wear patterns in patients with end-stage GOA and b) identify clinical and radiographic parameters that correlate with observed histopathological wear patterns. Methods: Eighteen humeral heads from patients undergoing anatomic total shoulder arthroplasty for end-stage osteoarthritis were divided radially into eight wedge-shaped zones. Each zone was subdivided into central and peripheral regions. Histologic analysis included measurements of cartilage and subchondral bone plate thickness, subchondral bone area, and cartilage structure was scored using the Osteoarthritis Research Society (OARSI) and modified Mankin systems. Clinical variables including patient history, physical exam, functional evaluation, and radiographic assessments were evaluated for correlations with humeral head characteristics. Results: Overall, humeral heads demonstrated a pattern of central and inferior cartilage damage, loss, and subchondral bone changes. However, within the group, composite maps of individual patient wear patterns demonstrated a sub-group of patients with a more focal inferior cartilage lesion. Overall, these more focal inferior lesions were associated with greater pre-operative range of motion (in both upper extremities), higher pre-operative SANE and ASES scores, female sex, non-dominant extremity, concentric wear patterns, and smaller inferior osteophytes. Conclusion: Humeral head cartilage wear patterns in GOA include central and inferior cartilage damage and loss. A histopathological distinction was identified between patients with more focal versus diffuse wear, which may manifest clinically with preservation of function and range of motion, and with less profound radiographical changes.

Current peri-operative imaging concepts surrounding shoulder arthroplasty.

Glenohumeral osteoarthritis is a prevalent degenerative disease that can lead to excruciating pain and debility. End-stage osteoarthritis can be treated by both conservative and surgical interventions. Along with a comprehensive history and physical exam, pre-operative imaging with plain radiographs, computerized tomography, and magnetic resonance imaging plays an essential role in the decision-making process guiding whether the patient undergoes a shoulder hemiarthroplasty, anatomic total shoulder arthroplasty, or a reverse total shoulder arthroplasty. The most important pre-operative imaging factors are the integrity of the rotator cuff and presence of significant glenoid erosion. Imaging is also critical postoperatively, as signs of prosthetic loosening, rotator cuff failure (especially involving the subscapularis), periprosthetic fracture, and stress fractures are important entities to recognize. This article will review pertinent imaging findings related to the pre- and post-operative management of patients with glenohumeral osteoarthritis.

Shoulder arthroplasty using mini-stem humeral components and a lesser tuberosity osteotomy.

PURPOSE: To determine whether lesser tuberosity osteotomy (LTO) and mini-stem humeral components (MSHCs) can be safely and effectively used together in total and hemi-shoulder arthroplasty (TSA/HHA). METHODS: This is a retrospective review of consecutive patients who underwent anatomic TSA/HHA utilizing combined LTO/MSHC with minimum 2-year follow-up. Six-week and final radiographs, range of motion, pain scores, and selected outcome measures were assessed. RESULTS: Seventy five shoulders with mean follow-up of 27.8 months (24-50 months) were analyzed. Sixty-seven (89.3%) shoulders had uneventful LTO healing. There were five (6.67%) LTO failures, one (1.33%) fibrous union, and two (2.67%) osteotomies that had displaced > 4 mm at 6 weeks; four of the five failures required open repair, including one converted to reverse TSA. The other failure, the fibrous union, and the two displaced osteotomies were without clinical deficits and elected for non-operative management. One patient required intraoperative conversion to a long stem due to concern that metaphyseal bone integrity was compromised, in part, by the LTO. Four (5.33%) stems subsided, with one of them also being frankly loose and requiring revision, while the other three were asymptomatic, not requiring treatment. No other stems were judged to be loose. Mean ASES, SANE, VAS, forward flexion, external rotation, and internal rotation all improved significantly (p < 0.001 for all). CONCLUSIONS: LTO/MSHC use is appropriate for TSA/HHA, achieving pain relief and functional improvement. Component loosening appears uncommon at early follow-up. Long-stem components should be available in case the metaphyseal bone is compromised. When performed properly, LTO/MSHC use is a safe and effective surgical strategy.

Thrombosis of the brachial artery after closed dislocation of the elbow.

The brachial artery is rarely injured after closed dislocation of the elbow. We describe an unusual variation of this injury, namely, a delayed thrombosis of the brachial artery after a closed dislocation sustained during a low-energy fall. This has not previously been described in the English literature, but may be more common than this suggests. We stress the importance of a thorough neurovascular examination and vigilance in regard to this potentially disastrous complication.

[Recurrent acute polyneuropathy and cutaneous vasculitis]. / Polyneuropathie aiguë récidivante et vasculite cutanée.

A patient with relapsing cutaneous vasculitis presented 3 times in 10 years with an acute extensive neuropathy and respiratory failure which fully recovered. The relationships between Guillain-Barré syndrome and vasculitis are discussed.