Bebryazulene, a new guaiane metabolite from the indian ocean gorgonian coral, bebryce grandicalyx

Bebryazulene (1), a new sesquiterpene having the guaiane skeleton, was isolated from the methanol-chloroform 1:2 extract of the Indian Ocean gorgonian coral Bebryce grandicalyx (Kuekenthal) collected in the lagoon of Mayotte. Structure assignment was based on interpretation of spectroscopic data. This new metabolite was very labile and reacted with 4-phenyl-3H-1,2,4-triazoline-3,5-dione to yield an unexpected adduct.

Several new isoprenoids from the soft coral sinularia erecta

Eight compounds were isolated from the Indo-Pacific soft coral Sinularia erecta (Tixier-Durivault, 1945) collected from the lagoon of Mayotte, Comoros Islands, northwest of Madagascar. Four of the compounds, namely the sesquiterpene germacrene D, the diterpenoids nephthenol and decaryiol, and norcembrene, are known. The other four are the new secondary metabolites germacrene E (1), epi-norcembrene (3), and two bis-pukalide diterpenes, mayotolides A and B (4 and 5). The structure of each of the compounds was determined by means of 1D and 2D NMR and MS spectroscopy in addition to some chemical transformations.