RESUMO
A 59-year-old man showed asynchronous development of noninfectious granulomatous aortitis with aneurysm, followed 9 months later by pulmonary capillaritis and glomerulonephritis in association with elevated serum antineutrophil cytoplasmic antibody levels. To our knowledge, the combination of large artery vasculitis and small vessel systemic vasculitis (capillaritis) has not been previously reported. This case may represent a hybrid type of systemic vasculitis combining features of giant cell arteritis and Wegener's granulomatosis.
Assuntos
Capilares/patologia , Arterite de Células Gigantes/patologia , Glomerulonefrite/patologia , Granulomatose com Poliangiite/patologia , Pulmão/irrigação sanguínea , Vasculite/patologia , Anticorpos/imunologia , Citoplasma/imunologia , Arterite de Células Gigantes/complicações , Glomerulonefrite/etiologia , Granulomatose com Poliangiite/complicações , Humanos , Masculino , Pessoa de Meia-Idade , Neutrófilos/imunologia , Vasculite/etiologiaRESUMO
We describe a case of adrenal myelolipoma that occurred in a 66-year-old male with an ACTH producing oat cell lung carcinoma. To our knowledge, this is the first case in which myelolipoma has occurred in association with ectopic ACTH-induced Cushing's syndrome. The literature is reviewed and the pathogenesis of myelolipoma is discussed.