Quality of life of patients with bilateral oophorectomy before the age of 45 for the treatment of endometriosis.

INTRODUCTION: The study aimed to evaluate the quality of life and associated factors among women who underwent bilateral oophorectomy (BO) before the age of 45 for the treatment of deep infiltrating endometriosis (DIE). MATERIALS AND METHODS: This cross-sectional study was carried out in 52 women who were treated from January 2014 to December 2019 in 2 public and private DIE surgical centers in Toulouse. All women answered the Menopausal Quality of Life questionnaire (MenQOL). Mean MenQOL scores were compared according to age at BO, smoking, BMI, level of education, delay between BO and the survey and post-BO hormone replacement therapy (HRT) using Mann-Whitney and Anova tests. Spearman's correlation coefficient was used to analyze the correlations between all the MEnQOL domain scores and clinical variables. The variables associated with the outcomes in univariate analyses with p < 0.2 were jointly evaluated using multiple linear regression. RESULTS: The mean age at the time of the survey was 43.4 ± 3.4 years while the mean age at BO was 40.5 ± 3.4 years. The mean MenQOL score was 3.96 (± 1.45), with the highest scores in the sexual (4.77) and vasomotor (4.01) domains. BMI and smoking were independently and significantly associated with the mean total MenQOL score, all domain scores being significantly higher in overweight/obese women. A trend towards worse MenQOL scores was found in patients who had BO before the age of 41. We did not find any difference according to whether or not they were taking HRT. CONCLUSION: This is a first study evaluating quality of life in a specific population of oophorectomized women under the age of 45 using MenQOL for DIE. While BO is effective in relieving pain in women with severe DIE, the induced premature menopause is associated with a poor quality of life, which deserves further attention.

[Pelvi-abdominal hematoma: a five years study]. / Hématome puerpéral pelvien: étude sur cinq années de suivi.

OBJECTIVES: To investigate the incidence of pelvi-abdominal hematoma, to identify associated factors and to describe modalities of diagnosis and management. PATIENTS AND METHODS: A retrospective observational study including all patients presenting with a pelvi-abdominal hematoma among women who delivered between January 2005 and December 2010 in Toulouse university hospital. RESULTS: Twenty five thousand, one hundred and eighty-four women delivered during the study period and nine women were included (estimated incidence: 1/4200 deliveries). The main associated obstetrical factors were perineal injuries (episiotomy or lacerations) in 100% of cases and instrumental extraction (spatula) in 50% of cases. Arterial embolisation was performed in one third of cases. No death was observed. CONCLUSION: Pelvi-abdominal hematoma is a severe and infrequent postpartum complication. A better knowledge of clinical and radiological presentations together with obstetrical associated factors will allow an early diagnosis and a multidisciplinary management.