RESUMO
A 5-year-old Quarter horse broodmare was evaluated for inappetence, depression, and diarrhea 13 days after aborting a 9-month gestation fetus. Clinical and laboratory examination ruled out uterine rupture and peritonitis. Ultrasonography of the uterus combined with cytological analysis of peritoneal fluid suggested the existence of diffuse lymphoma. A multicentric B-cell lymphoma involving the uterus and ovary was confirmed at necropsy and histopathological examination.
Lymhome multicentrique à cellules B comme cause possible d'avortement chez une jument poulinière Quarter Horse. Une jument Quarter horse de 5 ans a été présentée pour anorexie, baisse d'état général et diarrhée, trente jours après un avortement à 9 mois de gestation. Lors de l'examen clinique initial, rupture utérine et péritonite ont pu être éliminées. L'analyse cytologique des liquides péritonéaux et pleuraux aspirés suggéra un lymphome diffus confirmé en nécropsie lors de l'examen histopathologique.(Traduit par les auteurs).
Assuntos
Aborto Animal/etiologia , Doenças dos Cavalos/patologia , Linfoma de Células B/veterinária , Neoplasias Uterinas/veterinária , Animais , Feminino , Doenças dos Cavalos/etiologia , Cavalos , Linfoma de Células B/complicações , Linfoma de Células B/patologia , Metástase Neoplásica , Gravidez , Neoplasias Uterinas/diagnóstico , Neoplasias Uterinas/patologiaRESUMO
During computed tomography (CT), the appearance of disease involving the pulmonary acinus may be described using terms such as atelectasis, ground-glass opacity, or consolidation. These CT signs, however, have not been correlated with histologic findings in canine pulmonary disease. To facilitate interpretation of lung diseases by CT signs, our goals were to review the morphologic organization of the lung and evaluate the medical records of four dogs with different types of pulmonary acinar disease. Anatomic review focused on understanding the pulmonary acinus and the secondary pulmonary lobule; the secondary pulmonary lobule is a fundamental unit for interpretation in people. All dogs had similar CT findings of fully expanded lungs with increased attenuation and partial-to-complete obscuring of the pulmonary blood vessels. Histologic findings varied between dogs and included partial-to-complete filling of airspaces with cells or fluid, interstitial thickening, increased capillary blood volume, or a combination of these findings. Final diagnoses were hemorrhagic pneumonia, bronchiolar carcinoma, metastatic mammary adenocarcinoma, and pulmonary edema. In summary, the morphologic organization of the lungs is complex and has implications for diagnostic interpretation needing further evaluation in dogs. In this study, increased lung attenuation during CT due to disease localized to the pulmonary acini was due to the displacement of air from the lungs and not to the microscopic distribution of lesions within the pulmonary acinus. Imaging descriptors that classify diseases according to structures larger than the pulmonary acini, for example, regions of the secondary pulmonary lobule or larger, may be appropriate for dogs.
Assuntos
Doenças do Cão/diagnóstico por imagem , Doenças do Cão/patologia , Pneumopatias/veterinária , Pulmão/diagnóstico por imagem , Pulmão/patologia , Tomografia Computadorizada por Raios X/veterinária , Adenocarcinoma Bronquioloalveolar/diagnóstico por imagem , Adenocarcinoma Bronquioloalveolar/patologia , Adenocarcinoma Bronquioloalveolar/veterinária , Animais , Cães , Pulmão/anatomia & histologia , Pneumopatias/diagnóstico por imagem , Pneumopatias/patologia , Neoplasias Pulmonares/diagnóstico por imagem , Neoplasias Pulmonares/patologia , Neoplasias Pulmonares/secundário , Neoplasias Pulmonares/veterinária , Pneumonia/diagnóstico por imagem , Pneumonia/patologia , Pneumonia/veterinária , Edema Pulmonar/diagnóstico por imagem , Edema Pulmonar/patologia , Edema Pulmonar/veterináriaRESUMO
Anesthetic-associated death (AAD) in cats is infrequent, but occurs far more frequently than in people. Post-mortem investigations of AAD in cats are uncommon, and results only sporadically published. Here we report the findings in 54 cases of AAD in cats. Significant gross and/or microscopic pre-existing disease, including pulmonary, cardiac, and systemic disease, was detected in 33% of cases. Pulmonary disease was most frequently diagnosed (24% of cases), and included cases of Aelurostrongylus abstrusus infection (9% of cases). Heart disease, including two cases of hypertrophic cardiomyopathy, was less frequent (11% of cases). Four percent died from surgical complications. No significant gross or microscopic disease was detected in 63% of cases. Additional studies are needed to determine if these findings are representative of AAD in cats in other geographic areas or with access to veterinary care. This study demonstrates that post-mortem investigation of AADs is an important and worthwhile endeavor.