1.
Bull Exp Biol Med
; 161(5): 666-669, 2016 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27709386
RESUMO
We compared the intensity of apoptosis in the peri-infarction area of the brain after isolated and combined exposure to hypoxia and hypercapnia prior to focal ischemic stroke modeling. Hypoxia and hypercapnia reduced the number of TUNEL-positive cells in the peri-infarction area, and their combination was most effective in comparison with effects of isolated exposures. The maximum neuroprotective effect of combined exposure to hypoxia and hypercapnia in comparison with isolated exposures was determined by inhibition of apoptosis in the peri-infarction zone.
Assuntos
Apoptose , Isquemia Encefálica/patologia , Hipercapnia/patologia , Hipóxia Encefálica/patologia , Animais , Córtex Cerebral/patologia , Precondicionamento Isquêmico , Masculino , Fatores de Proteção , Ratos Wistar
2.
Patol Fiziol Eksp Ter
; (6): 42-5, 1987.
Artigo
em Russo
| MEDLINE
| ID: mdl-2832809