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1.
Sci Adv ; 5(4): eaav1555, 2019 04.
Artigo em Inglês | MEDLINE | ID: mdl-31032405

RESUMO

Optical fiber bundle microendoscopes are widely used for visualizing hard-to-reach areas of the human body. These ultrathin devices often forgo tunable focusing optics because of size constraints and are therefore limited to two-dimensional (2D) imaging modalities. Ideally, microendoscopes would record 3D information for accurate clinical and biological interpretation, without bulky optomechanical parts. Here, we demonstrate that the optical fiber bundles commonly used in microendoscopy are inherently sensitive to depth information. We use the mode structure within fiber bundle cores to extract the spatio-angular description of captured light rays-the light field-enabling digital refocusing, stereo visualization, and surface and depth mapping of microscopic scenes at the distal fiber tip. Our work opens a route for minimally invasive clinical microendoscopy using standard bare fiber bundle probes. Unlike coherent 3D multimode fiber imaging techniques, our incoherent approach is single shot and resilient to fiber bending, making it attractive for clinical adoption.


Assuntos
Tecnologia de Fibra Óptica , Luz , Fibras Ópticas , Algoritmos , Humanos , Imageamento Tridimensional , Modelos Teóricos , Imagem Óptica/instrumentação , Imagem Óptica/métodos
2.
Sci Rep ; 8(1): 3298, 2018 02 19.
Artigo em Inglês | MEDLINE | ID: mdl-29459650

RESUMO

Mobile phone microscopes are a natural platform for point-of-care imaging, but current solutions require an externally powered illumination source, thereby adding bulk and cost. We present a mobile phone microscope that uses the internal flash or sunlight as the illumination source, thereby reducing complexity whilst maintaining functionality and performance. The microscope is capable of both brightfield and darkfield imaging modes, enabling microscopic visualisation of samples ranging from plant to mammalian cells. We describe the microscope design principles, assembly process, and demonstrate its imaging capabilities through the visualisation of unlabelled cell nuclei to observing the motility of cattle sperm and zooplankton.

3.
Nanoscale ; 9(27): 9299-9304, 2017 Jul 13.
Artigo em Inglês | MEDLINE | ID: mdl-28675210

RESUMO

The nitrogen-vacancy (NV) centre in diamond is a unique optical defect that is used in many applications today and methods to enhance its fluorescence brightness are highly sought after. We observed experimentally an enhancement of the NV quantum yield by up to 7% in bulk diamond caused by an external magnetic field relative to the field-free case. This observation is rationalised phenomenologically in terms of a magnetic field dependence of the NV excited state triplet-to-singlet transition rate. The theoretical model is in good qualitative agreement with the experimental results at low excitation intensities. Our results significantly contribute to our fundamental understanding of the photophysical properties of the NV defect in diamond.

4.
Opt Lett ; 42(7): 1297-1300, 2017 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-28362753

RESUMO

Nanostructured and bulk silicon carbide (SiC) has recently emerged as a novel platform for quantum nanophotonics due to its harboring of paramagnetic color centers, having immediate applications as a single photon source and spin optical probes. Here, using ultra-short pulsed laser ablation, we fabricated from electron irradiated bulk 4H-SiC, 40-50 nm diameter SiC nanoparticles, fluorescent at 850-950 nm. This photoluminescence is attributed to the silicon vacancy color centers. We demonstrate that the original silicon vacancy color centers from the target sample were retained in the final nanoparticles solution, exhibiting excellent colloidal stability in water over several months. Our work is relevant for quantum nanophotonics, magnetic sensing, and biomedical imaging applications.


Assuntos
Compostos Inorgânicos de Carbono/química , Lasers , Microscopia de Fluorescência/métodos , Nanopartículas/química , Compostos de Silício/química , Cor
5.
Nanoscale ; 9(2): 497-502, 2017 Jan 05.
Artigo em Inglês | MEDLINE | ID: mdl-27942675

RESUMO

Bright and photostable fluorescence from nitrogen-vacancy (NV) centers is demonstrated in unprocessed detonation nanodiamond particle aggregates. The optical properties of these particles is analyzed using confocal fluorescence microscopy and spectroscopy, time resolved fluorescence decay measurements, and optically detected magnetic resonance experiments. Two particle populations with distinct optical properties are identified and compared to high-pressure high-temperature (HPHT) fluorescent nanodiamonds. We find that the brightness of one detonation nanodiamond particle population is on the same order as that of highly processed fluorescent 100 nm HPHT nanodiamonds. Our results may open the path to a simple and up-scalable route for the production of fluorescent NV nanodiamonds for use in bioimaging applications.

6.
Chem Commun (Camb) ; 52(19): 3850, 2016 Mar 07.
Artigo em Inglês | MEDLINE | ID: mdl-26883987
7.
Chem Commun (Camb) ; 50(65): 9172-5, 2014 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-24992893

RESUMO

Transient changes in the contact angle, Δθ ∼ 10°, of water on gold (Au) reveal reversible wetting of near hydrophobic Au films. The recovery time is temperature dependent. Surface flatness is investigated using AFM and profilometery.


Assuntos
Ouro/química , Água/química , Interações Hidrofóbicas e Hidrofílicas , Microscopia de Força Atômica , Propriedades de Superfície , Temperatura
8.
Opt Express ; 22(9): 11301-11, 2014 May 05.
Artigo em Inglês | MEDLINE | ID: mdl-24921827

RESUMO

An ideal optical cavity operates by confining light in all three dimensions. We show that a cylindrical waveguide can provide the longitudinal confinement required to form a two dimensional cavity, described here as a self-formed cavity, by locating a dipole, directed along the waveguide, on the interface of the waveguide. The cavity resonance modes lead to peaks in the radiation of the dipole-waveguide system that have no contribution due to the skew rays that exist in longitudinally invariant waveguides and reduce their Q-factor. Using a theoretical model, we evaluate the Q-factor and modal volume of the cavity formed by a dipole-cylindrical-waveguide system and show that such a cavity allows access to both the strong and weak coupling regimes of cavity quantum electrodynamics.

9.
Phys Rev Lett ; 111(21): 213603, 2013 Nov 22.
Artigo em Inglês | MEDLINE | ID: mdl-24313488

RESUMO

Operating reconfigurable quantum circuits with single photon sources is a key goal of photonic quantum information science and technology. We use an integrated waveguide device containing directional couplers and a reconfigurable thermal phase controller to manipulate single photons emitted from a chromium related color center in diamond. Observation of both a wavelike interference pattern and particlelike sub-Poissionian autocorrelation functions demonstrates coherent manipulation of single photons emitted from the chromium related center and verifies wave particle duality.

11.
Opt Express ; 19(3): 1860-5, 2011 Jan 31.
Artigo em Inglês | MEDLINE | ID: mdl-21369001

RESUMO

The internal structure of nanostructured air-silica fiber probes have been characterized using a combined focused ion beam and scanning electron microscopy technique. The collapse rate of the air-holes is shown to differ substantially between a regular photonic crystal fiber (PCF) and the quasi-periodic Fractal fiber. The integrity of the Fractal fiber structure is maintained down to an outer diameter as small as 120 nm, whereas the air-holes of the regular PCF begin to collapse when the outer diameter is approximately 820 nm. The observed smallest hole diameter of 10 nm is suggested to be due to physical limits imposed by the molecular structure of silica. These results confirm structural inferences made in previous publications.


Assuntos
Cristalização/métodos , Tecnologia de Fibra Óptica , Modelos Químicos , Nanoestruturas/química , Nanotecnologia/instrumentação , Simulação por Computador , Desenho de Equipamento , Análise de Falha de Equipamento , Fractais , Luz , Teste de Materiais , Fótons , Espalhamento de Radiação
12.
Phys Rev Lett ; 105(21): 217403, 2010 Nov 19.
Artigo em Inglês | MEDLINE | ID: mdl-21231353

RESUMO

We present direct imaging of the emission pattern of individual chromium-based single photon emitters in diamond and measure their quantum efficiency. By imaging the excited state transition dipole intensity distribution in the back focal plane of high numerical aperture objective, we determined its 3D orientation. Employing ion implantation techniques, the emitters were placed at various distances from the diamond-air interface. By comparing the decay rates from the single chromium emitters at different depths in the diamond crystal, we measured an average quantum efficiency of 28%.

13.
Opt Express ; 17(14): 11287-93, 2009 Jul 06.
Artigo em Inglês | MEDLINE | ID: mdl-19582042

RESUMO

The ability to manipulate nano-particles at the nano-scale is critical for the development of active quantum systems. This paper presents a technique to manipulate diamond nano-crystals at the nano-scale using a scanning electron microscope, nano-manipulator and custom tapered optical fibre probes. The manipulation of a approximately 300 nm diamond crystal, containing a single nitrogen-vacancy centre, onto the endface of an optical fibre is demonstrated. The emission properties of the single photon source post manipulation are in excellent agreement with those observed on the original substrate.


Assuntos
Nanotecnologia/métodos , Cristalização , Diamante/química , Desenho de Equipamento , Íons , Microscopia Confocal/métodos , Microscopia Eletrônica de Varredura/métodos , Nanotecnologia/instrumentação , Nitrogênio/química , Óptica e Fotônica , Fótons , Teoria Quântica , Silício/química , Temperatura , Fatores de Tempo
14.
Opt Express ; 17(3): 1772-80, 2009 Feb 02.
Artigo em Inglês | MEDLINE | ID: mdl-19189007

RESUMO

Scanning Near-field Optical Microscopy (SNOM) is the leading instrument used to image optical fields on the nanometer scale. A metal-coating is typically applied to SNOM probes to define a subwavelength aperture and minimize optical leakage, but the presence of such coatings in the near field of the sample can often cause a substantial change in the sample emission properties. For the first time, the authors demonstrate near-field imaging on a metal substrate with a metal-free probe made from a novel structured optical fiber, designed to maximize optical throughput and potentially remove the need for the metal.

15.
Opt Express ; 15(5): 2468-75, 2007 Mar 05.
Artigo em Inglês | MEDLINE | ID: mdl-19532484

RESUMO

A core component of all scanning near-field optical microscopy (SNOM) systems is the optical probe, which has evolved greatly but still represents the limiting component for the system. Here, we introduce a new type of optical probe, based on a Fractal Fibre which is a special class of photonic crystal fibre (PCF), to directly address the issue of increasing the optical throughput in SNOM probes. Optical measurements through the Fractal Fibre probes have shown superior power levels to that of conventional SNOM probes. The results presented in this paper suggest that a novel fibre design is critical in order to maximize the potential of the SNOM.

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