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1.
Sensors (Basel) ; 24(5)2024 Feb 25.
Artigo em Inglês | MEDLINE | ID: mdl-38475030

RESUMO

Structural health monitoring (SHM) has become paramount for developing cheaper and more reliable maintenance policies. The advantages coming from adopting such process have turned out to be particularly evident when dealing with plated structures. In this context, state-of-the-art methods are based on exciting and acquiring ultrasonic-guided waves through a permanently installed sensor network. A baseline is registered when the structure is healthy, and newly acquired signals are compared to it to detect, localize, and quantify damage. To this purpose, the performance of traditional methods has been overcome by data-driven approaches, which allow processing a larger amount of data without losing diagnostic information. However, to date, no diagnostic method can deal with varying environmental and operational conditions (EOCs). This work aims to present a proof-of-concept that state-of-the-art machine learning methods can be used for reducing the impact of EOCs on the performance of damage diagnosis methods. Generative artificial intelligence was leveraged to mitigate the impact of temperature variations on ultrasonic guided wave-based SHM. Specifically, variational autoencoders and singular value decomposition were combined to learn the influence of temperature on guided waves. After training, the generative part of the algorithm was used to reconstruct signals at new unseen temperatures. Moreover, a refined version of the algorithm called forced variational autoencoder was introduced to further improve the reconstruction capabilities. The accuracy of the proposed framework was demonstrated against real measurements on a composite plate.

2.
Polymers (Basel) ; 15(21)2023 Oct 30.
Artigo em Inglês | MEDLINE | ID: mdl-37959949

RESUMO

Blast loading represents a critical dynamic condition for engineering structures. While the response of metal materials to such a condition has been studied in detail, the behavior of composites has not been properly addressed yet. In this context, this work leverages numerical methods to assess the damage that occurs in a carbon-fiber-reinforced polymer plate subjected to close-range blast loading. Numerical analyses were carried out using two methods, i.e., the pure Lagrangian and hybrid coupled Eulerian-Lagrangian approaches. The simulations were validated against observations from a benchmark experimental test taken from the literature. The results showed that (i) the hybrid approach seems to be the most promising solution in terms of efficiency and accuracy; (ii) the Lagrangian approach can accurately reproduce the experimental observations, even though it comes with strong limitations; and (iii) the numerically predicted damage adheres to the experimentally observed damage, although the simulation outcome is influenced by the modeling technique used to describe the behavior of the composite material. We consider the approaches presented in this paper promising for investigation of blast-loaded composite structures, and further improvements can be achieved by (i) refining the description of the material behavior, e.g., by including the strain rate sensitivity; and (ii) better modeling the boundary conditions.

3.
Sensors (Basel) ; 23(7)2023 Mar 23.
Artigo em Inglês | MEDLINE | ID: mdl-37050466

RESUMO

The inverse finite element method (iFEM) is a model-based technique to compute the displacement (and then the strain) field of a structure from strain measurements and a geometrical discretization of the same. Different literature works exploit the error between the numerically reconstructed strains and the experimental measurements to perform damage identification in a structural health monitoring framework. However, only damage detection and localization are performed, without attempting a proper damage size estimation. The latter could be based on machine learning techniques; however, an a priori definition of the damage conditions would be required. To overcome these limitations, the present work proposes a new approach in which the damage is systematically introduced in the iFEM model to minimize its discrepancy with respect to the physical structure. This is performed with a maximum likelihood estimation framework, where the most accurate damage scenario is selected among a series of different models. The proposed approach was experimentally verified on an aluminum plate subjected to fatigue crack propagation, which enables the creation of a digital twin of the structure itself. The strain field fed to the iFEM routine was experimentally measured with an optical backscatter reflectometry fiber and the methodology was validated with independent observations of lasers and the digital image correlation.

4.
Sensors (Basel) ; 23(3)2023 Feb 03.
Artigo em Inglês | MEDLINE | ID: mdl-36772772

RESUMO

The inverse Finite Element Method (iFEM) has recently gained much popularity within the Structural Health Monitoring (SHM) field since, given sparse strain measurements, it reconstructs the displacement field of any beam or shell structure independently of the external loading conditions and of the material properties. However, in principle, the iFEM requires a triaxial strain measurement for each inverse finite element, which is seldom feasible in practical applications due to both costs and cabling-related limitations. To alleviate this problem several techniques to pre-extrapolate the measured strains have been developed, so that interpolated or extrapolated strain values are inputted to elements without physical sensors: the benefit is that the required number of sensors can be reduced. Nevertheless, whenever the monitored components comprise regions of different thicknesses, each region of constant thickness must be extrapolated separately, due to thickness-induced discontinuities in the strain field. This is the case in many practical applications, especially those concerning fiber-reinforced composite laminates. This paper proposes to extrapolate the measured strain field in a thickness-normalized space, where the thickness-induced trends are removed; this novel method can significantly decrease the number of required sensors, effectively reducing the costs of iFEM-based SHM systems. The method is validated in a simple but informative numerical case study, highlighting the potentialities and benefits of the proposed approach for more complex application scenarios.

5.
Sensors (Basel) ; 24(1)2023 Dec 29.
Artigo em Inglês | MEDLINE | ID: mdl-38203069

RESUMO

Condition monitoring of rotating shafts is essential for ensuring the reliability and optimal performance of machinery in diverse industries. In this context, as industrial systems become increasingly complex, the need for efficient data processing techniques is paramount. Deep learning has emerged as a dominant approach due to its capacity to capture intricate data patterns and relationships. However, a prevalent challenge lies in the black-box nature of many deep learning algorithms, which often operate without adhering to the underlying physical characteristics intrinsic to the studied phenomena. To address this limitation and enhance the fusion of data-driven methodologies with the fundamental physics of the system under study, this paper leverages physics-informed neural networks (PINNs). Specifically, a simple but realistic numerical case study of an extended Jeffcott rotor model, encompassing damping effects and anisotropic supports for a more comprehensive modelling, is considered. PINNs are used for the estimation of five parameters that characterize the health state of the system. These parameters encompass the radial and angular position of the static unbalance due to the disk installed on the shaft, the stiffness along the principal axes of elasticity, and the non-rotating damping coefficient. The estimation is conducted solely by exploiting the displacement signals from the centre of the disk and, to showcase the efficacy and precision provided by this novel methodology, various scenarios involving different constant rotational speeds are examined. Additionally, the impact of noisy input data is also taken into account within the analysis and the performance is compared to that of traditional optimization algorithms used for parameters estimation.

6.
Polymers (Basel) ; 14(20)2022 Oct 12.
Artigo em Inglês | MEDLINE | ID: mdl-36297859

RESUMO

Predicting the perforation limit of composite laminates is an important design aspect and is a complex task due to the multi-mode failure mechanism and complex material constitutive behaviour required. This requires high-fidelity numerical models for a better understanding of the physics of the perforation event. This work presents a numerical study on the perforation behaviour of a satin-weave S2-glass/epoxy composite subjected to low-velocity impact. A novel strain-rate-dependent finite-discrete element model (FDEM) is presented and validated by comparison with experimental data for impacts at several energies higher and lower than their perforation limit. The strain rate sensitivity was included in the model by developing a novel user-defined material model, which had a rate-dependent bilinear traction separation cohesive behaviour, implemented using a VUSDFLD subroutine in Abaqus/Explicit. The capability of the model in predicting the perforation limit of the composite was investigated by developing rate-sensitive and insensitive models. The results showed that taking the strain rate into account leads to more accurate predictions of the perforation limit and damage morphology of the laminate subjected to impacts at different energies. The experimental penetration threshold of 89 J was estimated as 79 J by the strain-rate-sensitive models, which was more accurate compared to 52 J predicted by the strain-rate-insensitive model. Additionally, the coupling between interlaminar and intralaminar failure modes in the models led to a more accurate prediction of the delamination area when considering the rate sensitivity.

7.
Sensors (Basel) ; 21(4)2021 Feb 17.
Artigo em Inglês | MEDLINE | ID: mdl-33671137

RESUMO

The inverse Finite Element Method (iFEM) is receiving more attention for shape sensing due to its independence from the material properties and the external load. However, a proper definition of the model geometry with its boundary conditions is required, together with the acquisition of the structure's strain field with optimized sensor networks. The iFEM model definition is not trivial in the case of complex structures, in particular, if sensors are not applied on the whole structure allowing just a partial definition of the input strain field. To overcome this issue, this research proposes a simplified iFEM model in which the geometrical complexity is reduced and boundary conditions are tuned with the superimposition of the effects to behave as the real structure. The procedure is assessed for a complex aeronautical structure, where the reference displacement field is first computed in a numerical framework with input strains coming from a direct finite element analysis, confirming the effectiveness of the iFEM based on a simplified geometry. Finally, the model is fed with experimentally acquired strain measurements and the performance of the method is assessed in presence of a high level of uncertainty.

8.
Materials (Basel) ; 14(3)2021 Jan 29.
Artigo em Inglês | MEDLINE | ID: mdl-33573014

RESUMO

In the case of protection of transportation systems, the optimization of the shield is of practical interest to reduce the weight of such components and thus increase the payload or reduce the fuel consumption. As far as metal shields are concerned, some investigations based on numerical simulations showed that a multi-layered configuration made of layers of different metals could be a promising solution to reduce the weight of the shield. However, only a few experimental studies on this subject are available. The aim of this study is therefore to discuss whether or not a monolithic shield can be substituted by a double-layered configuration manufactured from two different metals and if such a configuration can guarantee the same perforation resistance at a lower weight. In order to answer this question, the performance of a ballistic shield constituted of a layer of high-strength steel and a layer of an aluminum alloy impacted by an armor piercing projectile was investigated in experimental tests. Furthermore, an axisymmetric finite element model was developed. The effect of the strain rate hardening parameter C and the thermal softening parameter m of the Johnson-Cook constitutive model was investigated. The numerical model was used to understand the perforation process and the energy dissipation mechanism inside the target. It was found that if the high-strength steel plate is used as a front layer, the specific ballistic energy increases by 54% with respect to the monolithic high-strength steel plate. On the other hand, the specific ballistic energy decreases if the aluminum plate is used as the front layer.

9.
Sensors (Basel) ; 20(9)2020 Apr 29.
Artigo em Inglês | MEDLINE | ID: mdl-32365708

RESUMO

Maximum loads acting on aircraft structures generally arise when the aircraft is undergoing some form of acceleration, such as during landing. Landing, especially when considering rotorcrafts, is thus crucial in determining the operational load spectrum, and accurate predictions on the actual health/load level of the rotorcraft structure cannot be achieved unless a database comprising the structural response in various landing conditions is available. An effective means to create a structural response database relies on the modeling and simulation of the items and phenomena of concern. The structural response to rotorcraft landing is an underrated topic in the open scientific literature, and tools for the landing event simulation are lacking. In the present work, a coupled sequential simulation strategy is proposed and experimentally verified. This approach divides the complex landing problem into two separate domains, namely a dynamic domain, which is ruled by a multibody model, and a structural domain, which relies on a finite element model (FEM). The dynamic analysis is performed first, calculating a set of intermediate parameters that are provided as input to the subsequent structural analysis. Two approaches are compared, using displacements and forces at specific airframe locations, respectively, as the link between the dynamic and structural domains.

10.
Sensors (Basel) ; 19(6)2019 Mar 14.
Artigo em Inglês | MEDLINE | ID: mdl-30875726

RESUMO

Low-velocity impacts represent a major concern for aeronautical structures, sometimes producing barely detectable damage that could severely hamper the aircraft safety, even with regards to metallic structures. For this reason, the development of an automated impact monitoring system is desired. From a passive monitoring perspective, any impact generates a strain wave that can be acquired using sensor networks; signal processing techniques allow for extracting features useful for impact identification, possibly in an automatic way. However, impact wave characteristics are related to the impactor stiffness; this presents a problem for the evaluation of an impact-related feature and for the development of an automatic approach to impact identification. This work discusses the problem of reducing the influence of the impactor stiffness on one of the features typically characterizing the impact event, i.e., the time of arrival (TOA). Two passive sensor networks composed of accelerometers and piezoelectric sensors are installed on two metallic specimens, consisting of an aluminum skin and a sandwich panel, with aluminum skins and NOMEXTM honeycomb core. The effect of different impactor stiffnesses is investigated by resorting to an impact hammer, equipped with different tips. Subsequently, a method for data processing is defined to obtain a feature insensitive to the impactor stiffness, and this method is applied to multiple impact signals for feature uncertainty evaluation.

11.
Materials (Basel) ; 10(7)2017 Jul 13.
Artigo em Inglês | MEDLINE | ID: mdl-28773154

RESUMO

A novel fiber optic sensing technology for high frequency dynamics detection is proposed in this paper, specifically tailored for structural health monitoring applications based on strain wave analysis, for both passive impact identification and active Lamb wave monitoring. The sensing solution relies on a fiber optic-based interferometric architecture associated to an innovative coherent detection scheme, which retrieves in a completely passive way the high-frequency phase information of the received optical signal. The sensing fiber can be arranged into different layouts, depending on the requirement of the specific application, in order to enhance the sensor sensitivity while still ensuring a limited gauge length if punctual measures are required. For active Lamb wave monitoring, this results in a sensing fiber arranged in multiple loops glued on an aluminum thin panel in order to increase the phase signal only in correspondence to the sensing points of interest. Instead, for passive impact identification, the required sensitivity is guaranteed by simply exploiting a longer gauge length glued to the structure. The fiber optic coherent (FOC) sensor is exploited to detect the strain waves emitted by a piezoelectric transducer placed on the aluminum panel or generated by an impulse hammer, respectively. The FOC sensor measurements have been compared with both a numerical model based on Finite Elements and traditional piezoelectric sensors, confirming a good agreement between experimental and simulated results for both active and passive impact monitoring scenarios.

12.
Ultrasonics ; 60: 51-64, 2015 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25746761

RESUMO

This research investigates a Lamb-wave based structural health monitoring approach matching an out-of-phase actuation of a pair of piezoceramic transducers at low frequency. The target is a typical quasi-isotropic carbon fibre reinforced polymer aeronautical laminate subjected to artificial, via Teflon patches, and natural, via suitable low velocity drop weight impact tests, delaminations. The performance and main influencing factors of such an approach are studied through a Design of Experiment statistical method, considering both Pulse Echo and Pitch Catch configurations of PZT sensors. Results show that some factors and their interactions can effectively influence the detection of a delamination-like damage.

13.
Eur J Med Chem ; 46(7): 2797-806, 2011 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21531055

RESUMO

In continuing the search for more effective 5-arylidene-4-thiazolidinones as aldose reductase inhibitors, a new set of suitably substituted compounds (4, 5 and 8) was explored. Acetic acids 5, particularly 5a and 5h, proved to be interesting inhibitors of the enzyme as well as excellent antioxidant agents that are potentially able to counteract the oxidative stress associated with both diabetic complications as well as other pathologies. Molecular docking experiments supported SAR studies.


Assuntos
Aldeído Redutase/antagonistas & inibidores , Antioxidantes/síntese química , Inibidores Enzimáticos/síntese química , Tiazolidinedionas/síntese química , Acetatos/química , Aldeído Redutase/química , Animais , Antioxidantes/farmacologia , Bovinos , Complicações do Diabetes/prevenção & controle , Inibidores Enzimáticos/farmacologia , Humanos , Simulação de Acoplamento Molecular , Estresse Oxidativo/efeitos dos fármacos , Relação Estrutura-Atividade , Tiazolidinedionas/farmacologia
14.
Bioorg Med Chem Lett ; 21(1): 200-3, 2011 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-21129963

RESUMO

2-Thioxo-4-thiazolidinone derivatives were evaluated as aldose reductase inhibitors (ARIs) and most of them exhibited good or excellent in vitro efficacy. Out of the tested compounds, most N-unsubstituted analogues were found to possess inhibitory effects at low micromolar doses and two of them exhibited higher potency than sorbinil, used as a reference drug. The insertion of an acetic chain on N-3 of the thiazolidinone scaffold led to analogues with submicromolar affinity for ALR2 and IC(50) values very similar to that of epalrestat, the only ARI currently used in therapy.


Assuntos
Aldeído Redutase/antagonistas & inibidores , Inibidores Enzimáticos/química , Tiazolidinedionas/química , Aldeído Redutase/metabolismo , Animais , Bovinos , Inibidores Enzimáticos/síntese química , Inibidores Enzimáticos/farmacologia , Imidazolidinas/química , Imidazolidinas/farmacologia , Relação Estrutura-Atividade , Tiazolidinedionas/síntese química , Tiazolidinedionas/farmacologia
15.
Bioorg Med Chem ; 18(11): 4049-55, 2010 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-20452228

RESUMO

Non-carboxylic acid containing bioisosteres of (5-arylidene-2,4-dioxothiazolidin-3-yl)acetic acids, which are active as aldose reductase (ALR2) inhibitors, were designed by replacing the carboxylic group with the trifluoromethyl ketone moiety. The in vitro evaluation of the ALR2 inhibitory effects of these trifluoromethyl substituted derivatives led to the identification of two inhibitors effective at low micromolar doses. It was further confirmed that a carboxylic chain on N-3 of the thiazolidinedione scaffold is a determining requisite to obtain the highest efficacy levels; however, it is not essential for the interaction with the target enzyme and it can be replaced by different polar groups, thus obtaining less ionised or unionised inhibitors.


Assuntos
Aldeído Redutase/antagonistas & inibidores , Inibidores Enzimáticos/química , Cetonas/síntese química , Animais , Clorofluorcarbonetos de Metano , Humanos , Cetonas/farmacologia , Relação Estrutura-Atividade , Tiazolidinedionas
16.
Eur J Med Chem ; 45(3): 1140-5, 2010 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-20036445

RESUMO

The structure of aldehyde reductase (ALR1) in ternary complex with the coenzyme NADPH and [5-(3-carboxymethoxy-4-methoxybenzylidene)-2,4-dioxothiazolidin-3-yl]acetic acid (CMD), a potent inhibitor of aldose reductase (ALR2), was determined at 1.99A resolution. The partially disordered inhibitor formed a tight network of hydrogen bonds with the active site residues (Tyr50 and His113) and coenzyme. Molecular modelling calculations and inhibitory activity measurements of CMD and [5-(3-hydroxy-4-methoxybenzylidene)-2,4-dioxothiazolidin-3-yl]acetic acid (HMD) indicated that pi-stacking interactions with several conserved active site tryptophan residues and hydrogen-bonding interactions with the non-conserved C-terminal residue Leu300 in ALR2 (Pro301 in ALR1) contributed to inhibitor selectivity. In particular for the potent inhibitor CMD, the rotameric state of the conserved residue Trp219 (Trp220 in ALR1) is important in forming a pi-stacking interaction with the inhibitor in ALR2 and contributes to the difference in the binding of the inhibitor to the enzymes.


Assuntos
Aldeído Redutase/antagonistas & inibidores , Inibidores Enzimáticos/química , Aldeído Redutase/química , Domínio Catalítico , Cristalografia por Raios X , Ligação de Hidrogênio , Concentração Inibidora 50 , Modelos Moleculares , Estrutura Molecular , Tiazolidinedionas/química
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