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2.
Ned Tijdschr Geneeskd ; 141(20): 992-8, 1997 May 17.
Artigo em Holandês | MEDLINE | ID: mdl-9340555

RESUMO

Lichen sclerosus, formerly called lichen sclerosus et atrophicus, is a chronic skin disease manifesting itself mostly in the perineal region and often associated with itching. Characteristic elements are well-defined depigmentation and degeneration of the skin sometimes showing haemorrhagic bullae or teleangiectases. The skin grows thinner and shrinks. Malignant degeneration is rare. The prevalence is 1:300 to 1:1000. The condition occurs more often in females than in males and more often in adults than in children. Drug treatment (symptomatic) comprises local application of corticosteroids, anaesthetics and/or sex hormones. In case of insufficient response, cryotherapy is a good alternative. Chemical and surgical neurotomy are also sometimes applied, with fairly poor results. In refractory symptoms, excision of the affected skin, possibly with transplantation using a pedicled skin flap, may lead to mitigation.


Assuntos
Líquen Escleroso e Atrófico/cirurgia , Cirurgia Plástica/métodos , Corticosteroides/uso terapêutico , Anestésicos/uso terapêutico , Feminino , Doenças dos Genitais Femininos/cirurgia , Doenças dos Genitais Masculinos/cirurgia , Hormônios Esteroides Gonadais/uso terapêutico , Humanos , Líquen Escleroso e Atrófico/diagnóstico , Líquen Escleroso e Atrófico/tratamento farmacológico , Masculino , Pessoa de Meia-Idade , Prurido/etiologia , Telangiectasia/etiologia
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