[A case of Schmidt's syndrome]. / Przypadek zespolu Schmidta.

A typical case of Schmidt syndrome is reported. The syndrome comprises signs of primary adrenocortical failure and hypothyroidism. Other endocrine and non-endocrine immunopathies may be present also, such as type I diabetes, gonadal failure, Addison-Biermer anaemia, myasthenia gravis, vitiligo or alopecia areata. The possibility of these concomitant changes should be taken into account in the treatment of Schmidt syndrome. The case in a 52-year-old woman is reported in view of rare occurrence of thr syndrome and its few descriptions in the Polish literature as well as diagnostic difficulties.

[A case associating primary parathyroid hyperfunction with hyperthyroidism]. / Przypadek skojarzenia pierwotnej nadczynnosci przytarczyc z nadczynnoscia tarczycy.

A case of rare association of hyperparathyroidism with fully developed hyperthyroidism appearing in a woman 23 years old with advanced generalized cystic fibrosis has been presented.

[Atypical course of histiocytosis X]. / Nietypowy przebieg histiocytozy X.

A 48-year-old female patient was admitted because of increasing in size xanthomas of the eyelids lasting since 9 years (despite surgical treatment) and narrowing considerably the palpebral fissures. Five years earlier the diagnosis of type II b hyperlipoproteinaemia was made. Presently, besides palpebral lesions, a painless plum-sized tumour was found in the right frontoparietal area and two hard tumours of similar size were situated bilaterally in the submandibular area. In the biopsy specimens of all these tumours histological examination demonstrated lymphoid cells with numerous germinative centres. The diagnosis of histiocytosis X was followed by treatment with prednisone which resulted in a decrease in the size of palpebral xanthomas and improvement of the general condition of the patient.