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1.
Rev Esc Enferm USP ; 57: e20230009, 2023.
Artigo em Inglês, Português | MEDLINE | ID: mdl-38131439

RESUMO

OBJECTIVE: To understand the meanings attributed to family relationships by women who have experienced domestic violence. METHOD: Explanatory study using Symbolic Interactionism and Grounded Theory as references. Data were collected from March to November 2021, through online interviews with 23 women found on the social media application Facebook®. RESULTS: Data analysis allowed the construction of a theoretical model consisting of three processes: "We learned that it was normal to be mistreated": experiencing a context of violence in the family of origin; "I just wanted a family": experiencing partner violence and redefining family relationships in the context of violence. CONCLUSION: The meanings attributed to family relationships are elaborated and modified according to the interpretation, trajectory of confrontation, and interactions of women with other individuals and objects in the social web, over time. When experiencing domestic violence, women give new meaning to their feelings and begin to attribute new values, emotions, and empathy to family relationships, expanding their understanding of their weaknesses and potential.


Assuntos
Violência Doméstica , Humanos , Feminino , Teoria Fundamentada , Violência Doméstica/psicologia , Relações Familiares , Emoções
2.
J Inorg Biochem ; 245: 112233, 2023 08.
Artigo em Inglês | MEDLINE | ID: mdl-37141763

RESUMO

In the search for new 5-LOX inhibitors, two ferrocenyl Schiff base complexes functionalized with catechol ((ƞ5-(E)-C5H4-NCH-3,4-benzodiol)Fe(ƞ5-C5H5) (3a)) and vanillin ((ƞ5-(E)-C5H4-NCH-3-methoxy-4-phenol)Fe(ƞ5-C5H5) (3b)) were obtained. Complexes 3a and 3b were biologically evaluated as 5-LOX inhibitors showed potent inhibition compared to their organic analogs (2a and 2b) and known commercial inhibitors, with IC50 = 0.17 ± 0.05 µM for (3a) and 0.73 ± 0.06 µM for (3b) demonstrated a highly inhibitory and potent effect against 5-LOX due to the incorporation of the ferrocenyl fragment. Molecular dynamic studies showed a preferential orientation of the ferrocenyl fragment toward the non-heme iron of 5-LOX, which, together with electrochemical and in-vitro studies, allowed us to propose a competitive redox deactivation mechanism mediated by water, where Fe(III)-enzyme can be reduced by the ferrocenyl fragment. An Epa/IC50 relationship was observed, and the stability of the Schiff bases was evaluated by SWV in the biological medium, observing that the hydrolysis does not affect the high potency of the complexes, making them interesting alternatives for pharmacological applications.


Assuntos
Araquidonato 5-Lipoxigenase , Bases de Schiff , Bases de Schiff/farmacologia , Bases de Schiff/química , Araquidonato 5-Lipoxigenase/química , Araquidonato 5-Lipoxigenase/metabolismo , Compostos Férricos , Simulação de Dinâmica Molecular , Oxirredução , Inibidores de Lipoxigenase/farmacologia , Relação Estrutura-Atividade
3.
Rev. Esc. Enferm. USP ; 57: e20230009, 2023. graf
Artigo em Inglês, Português | LILACS, BDENF - Enfermagem | ID: biblio-1529428

RESUMO

ABSTRACT Objective: To understand the meanings attributed to family relationships by women who have experienced domestic violence. Method: Explanatory study using Symbolic Interactionism and Grounded Theory as references. Data were collected from March to November 2021, through online interviews with 23 women found on the social media application Facebook®. Results: Data analysis allowed the construction of a theoretical model consisting of three processes: "We learned that it was normal to be mistreated": experiencing a context of violence in the family of origin; "I just wanted a family": experiencing partner violence and redefining family relationships in the context of violence. Conclusion: The meanings attributed to family relationships are elaborated and modified according to the interpretation, trajectory of confrontation, and interactions of women with other individuals and objects in the social web, over time. When experiencing domestic violence, women give new meaning to their feelings and begin to attribute new values, emotions, and empathy to family relationships, expanding their understanding of their weaknesses and potential.


RESUMEN Objetivo: Comprender los significados atribuidos a las relaciones familiares por mujeres que han vivido violencia doméstica. Método: Estudio explicativo que utilizó como referentes el Interaccionismo Simbólico y la Teoría Fundamentada. Los datos fueron recolectados de marzo a noviembre de 2021, a través de entrevistas online a 23 mujeres encontradas en la red social Facebook®. Resultados: El análisis de los datos permitió la construcción de un modelo teórico, compuesto por tres procesos: "Aprendimos que era normal que nos maltrataran": experiencia en un contexto de violencia en la familia de origen; "Solo quería una familia": experiencia de la violencia en la pareja y redefinición de las relaciones familiares en el contexto de la violencia. Conclusión: Los significados atribuidos a las relaciones familiares se elaboran y modifican según la interpretación, trayectoria de confrontación e interacciones de las mujeres con otros individuos y objetos del tejido social, a lo largo del tiempo. Al vivir violencia doméstica, las mujeres dan un nuevo significado a sus sentimientos y comienzan a atribuir nuevos valores, emociones y empatía a las relaciones familiares, ampliando su comprensión de sus debilidades y potencialidades.


RESUMO Objetivo: Compreender os significados atribuídos às relações familiares, por mulheres que vivenciaram violência doméstica. Método: Estudo explicativo que utilizou como referenciais o Interacionismo Simbólico e a Teoria Fundamentada nos Dados. Os dados foram coletados no período de março a novembro de 2021, por meio de entrevistas on-line com 23 mulheres localizadas na rede social Facebook®. Resultados: A análise dos dados permitiu a construção de um modelo teórico, constituído por três processos: "A gente aprendeu que era normal ser maltratada": experienciando um contexto de violência na família de origem; "Eu só queria uma família": vivenciando violência pelo companheiro e Ressignificando as relações familiares no contexto de violência. Conclusão: Os significados atribuídos às relações familiares são elaborados e modificados conforme a interpretação, trajetória no enfrentamento e interações das mulheres com outros indivíduos e objetos no tecido social, ao longo do tempo. Ao vivenciar a violência doméstica as mulheres ressignificam seus sentimentos e passam a atribuir novos valores, emoções e empatia às relações familiares, ampliando a compreensão de suas fragilidades e potencialidades.


Assuntos
Humanos , Saúde da Mulher , Teoria Fundamentada , Cuidados de Enfermagem , Violência Doméstica , Relações Familiares
4.
Food Chem ; 367: 130676, 2022 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-34365250

RESUMO

Antimony(III) is a rare electroactive specie present on Earth, whose concentration is not typically determined. The presence of high concentrations of antimony is responsible for a variety of diseases, which makes it desirable to find convenient and reliable methods for its determination. We have developed a convenient glassy carbon modified electrode with electroreduced graphene oxide GC/rGO for the first time determination of Sb(III) in commercial lettuce, celery, and beverages. The surface of the electrode was characterized by scanning electron microscopy (SEM) and cyclic voltammetry, indicating a heterogeneous and rough surface with a real area of 0.28 cm2, which is ~2.5 times the area of GC. The optimal chemical and electrochemical parameters used were: sodium acetate buffer (pH = 4.3), an accumulation potential of -1.0 V and an accumulation time of 150 s. The analytical validation was developed evaluating the linear range (10-60 µg L-1), limit of detection (2.5 µg L-1), accuracy, repetibility and reproducibility with satisfactory results (relative standard deviation (RSD) values lower than 10%). All the analyzes performed in real samples by stripping voltammetry were compared with GF-AAS, showing statistically similar values, demonstrating that GC/rGO could be effectively applied in the analysis of food samples.


Assuntos
Grafite , Antimônio/análise , Bebidas , Eletrodos , Plantas Comestíveis , Reprodutibilidade dos Testes
5.
RSC Adv ; 10(37): 21963-21973, 2020 Jun 08.
Artigo em Inglês | MEDLINE | ID: mdl-35516608

RESUMO

This article reports the synthesis and characterisation of two lower rim calix[4]arene derivatives with thiourea as spacer and pyrene or methylene-pyrene as fluorophore. Both derivatives exhibit a fluorimetric response towards Hg2+, Ag+ and Cu2+. Only methylene-pyrenyl derivative 2 allows for selective detection of Hg2+ and Ag+ by enhancement or decrease of excimer emission, respectively. The limits of detection of 2 are 8.11 nM (Hg2+) and 2.09 nM (Ag+). DFT and TD-DFT computational studies were carried out and used to identify possible binding modes that explain the observed response during fluorescence titrations. Calculations revealed the presence of different binding sites depending on the conformation of 2, which suggest a reasonable explanation for non-linear changes in fluorescence depending on the physical nature of the interaction between metal centre and conformer. INHIBITION and IMPLICATION logic gates have also been generated monitoring signal outputs at pyrene monomer (395 nm) and excimer (472 nm) emission, respectively. Thus 2 is a potential primary sensor towards Ag+ and Hg2+ able to configure two different logic gate operations.

6.
Acta Paul. Enferm. (Online) ; 33: eAPE20190150, 2020. tab
Artigo em Português | LILACS, BDENF - Enfermagem | ID: biblio-1130552

RESUMO

Resumo Objetivo Identificar fatores associados às práticas de violência conjugal em mulheres de apenados. Métodos Estudo transversal realizado com mulheres que visitavam seus parceiros em uma Penitenciária do estado do Paraná. Os dados foram coletados no período de março a julho de 2018, com aplicação do Check-list de Avaliação de Risco de Violência contra Parceira Íntima. Na análise dos dados foi utilizada estatística descritiva, teste de associação de qui-quadrado e estimativas de Razão de Prevalência a partir de modelos de regressão de Poisson. Resultados Os fatores associados à prática de violência foram: estado civil, religião, presença de filhos e uso de substâncias químicas por parte do parceiro. Os tipos mais frequentes de violência foram: ameaças, impedimento da procura de serviços de saúde e privação de contato com terceiros. Conclusão Os fatores sociodemográficos influenciam a ocorrência de violência conjugal, e a detecção precoce pode ajudar no rastreamento de mulheres em risco e no estabelecimento de intervenções, pois são comportamentos passíveis de alteração.


Resumen Objetivo Identificar factores asociados a las prácticas de violencia conyugal en mujeres de presidiarios. Métodos Estudio transversal realizado con mujeres que visitaban a sus parejas en una penitenciaría del estado de Paraná. Los datos se recolectaron en el período de marzo a julio de 2018, mediante aplicación de Check-list de Evaluación de Riesgo de Violencia contra la Pareja. Para analizar los datos se utilizó estadística descriptiva, prueba de relación de ji cuadrado y estimativas de razón de prevalencia a partir de modelos de regresión de Poisson. Resultados Los factores asociados a la práctica de violencia fueron: estado civil, religión, presencia de hijos y uso de sustancias químicas por parte del compañero. Los tipos de violencia más frecuentes fueron: amenazas, impedimento para obtener servicios de salud y privación de contacto con terceros. Conclusión Los factores sociodemográficos influyen en los casos de violencia conyugal y la detección temprana puede ayudar a rastrear mujeres en riesgo y a establecer intervenciones, ya que son comportamientos que pueden modificarse.


Abstract Objective To identify the factors associated with conjugal violence practices in convicted women. Methods A cross-sectional study conducted with women who visited their partners in a prison in the state of Paraná. Data were collected from March to July 2018, using the Checklist for Assessing the Risk of Violence against Intimate Partners. In the data analysis, descriptive statistics, Chi-Square Test association and Prevalence Ratio estimates using Poisson Regression models were used. Results The factors associated with violence practice were: marital status, religion, presence of children and use of chemical substances by the partner. The most frequent types of violence were threats, impediment of seeking health services and deprivation of contact with third parties. Conclusion Sociodemographic factors influence the occurrence of conjugal violence, and early detection can help in the screening of women at risk and in the establishment of interventions, as they are behaviors that can be changed.


Assuntos
Humanos , Feminino , Adulto , Prisioneiros , Violência contra a Mulher , Violência por Parceiro Íntimo , Epidemiologia Descritiva , Estudos Transversais , Inquéritos e Questionários
7.
J Phys Chem A ; 123(43): 9274-9281, 2019 Oct 31.
Artigo em Inglês | MEDLINE | ID: mdl-31587556

RESUMO

The photoinduced redox reactions of two organometallic chalcones: trans, E, (η5-C5H4C(O)CH═CH-4-benzo-15-crown-5)Re(CO)3, 1, and trans, E, (η5-C5H4C(O)CH═CH-4-benzo-15-crown-5)Fe(η5-C5H4C(O)CH═CH-4-benzo-15-crown-5), 2, were investigated in fluid solution using the flash photolysis technique. For a better understanding of the photoinduced redox processes of these organometallic chalcones, an electron donor, triethylamine (TEA), and an electron acceptor, methylviologen dichloride (MVCl2), were chosen. Two parallel reaction paths for the decay of the intermediate 1-I, that is, the anion radical of 1, were observed in the presence of TEA. One generates a radical anion, while the other reaction path produces the Z isomer. Instead, the photoinduced reaction of 2 with TEA in MeOH generates an intense absorption band at λmax = 660 nm, which is attributed to a 2-I·MeOH adduct. The oxidative process between 1-I and MV2+ in CH3CN generates transient spectra consistent with the formation of the radical cation MV•+. In contrast, the photoinduced reaction between 2 and MV2+ showed that the generation of MV•+ occurs through a complex mechanism. MV•+ is formed in two steps where the first one is the formation of an adduct between the long-lived metal-to-ligand charge transfer (MLCT)Fe→Chalcone excited state and MV2+. These results have shown that intermediates 1-I and 2-I can function as photo-oxidants and photoreductants better than the chalcone short-lived excited states.

8.
J Am Chem Soc ; 141(39): 15605-15610, 2019 10 02.
Artigo em Inglês | MEDLINE | ID: mdl-31536338

RESUMO

The formation of oligomeric soluble aggregates is related to the toxicity of amyloid peptides and proteins. In this manuscript, we report the use of a ruthenium polypyridyl complex ([Ru(bpy)2(dpqp)]2+) to track the formation of amyloid oligomers at different times using photoluminescence anisotropy. This technique is sensitive to the rotational correlation time of the molecule under study, which is consequently related to the size of the molecule. [Ru(bpy)2(dpqp)]2+ presents anisotropy values of zero when free in solution (due to its rapid rotation and long lifetime) but larger values as the size and concentration of amyloid-ß (Aß) oligomers increase. Our assays show that Aß forms oligomers immediately after the assay is started, reaching a steady state at ∼48 h. SDS-PAGE, DLS, and TEM were used to confirm and characterize the formation of oligomers. Our experiments show that the rate of formation for Aß oligomers is temperature dependent, with faster rates as the temperature of the assay is increased. The probe was also effective in monitoring the formation of α-synuclein oligomers at different times.


Assuntos
Amiloide/química , Medições Luminescentes/métodos , Polímeros/química , Anisotropia , Processos Fotoquímicos , Compostos de Rutênio/química
9.
Rev. pesqui. cuid. fundam. (Online) ; 11(2, n. esp): 540-546, jan. 2019. tab
Artigo em Inglês, Português | LILACS, BDENF - Enfermagem | ID: biblio-969328

RESUMO

Objective: The study's goal has been to identify the needs of the relatives of people hospitalized in an Intensive Care Unit from the interior of the Paraná State. Methods: Data were collected from May to September 2017, through the application of the Critical Care Family Needs Inventory (CCFNI) to 55 patients' family members. It was performed a descriptive and inferential analysis. Results: The most valued needs were those related to information, safety in knowing that the family member is receiving the best treatment and having access/ possibility of being able to talk with the physician at the visit time. Conclusion: Knowing the needs of family members is an important tool to assess the aspects related to the delivered care, and also provides subsidies for implementing actions that guarantee better quality of care for the patients and their families


Objetivo: Identificar as necessidades dos familiares de pessoas internadas em uma Unidade de Terapia Intensiva (UTI) no interior do Estado do Paraná. Método: Os dados foram coletados no período de maio à setembro de 2017, por meio da aplicação do Inventário de Necessidades e Estressores de Familiares em Terapia Intensiva (INEFTI) a 55 familiares. Realizado análise descritiva e inferencial. Resultados: As necessidades mais valorizadas foram as relacionadas com informação, segurança em saber que o familiar está recebendo o melhor tratamento e de ter acesso/possibilidade de poder conversar com o médico no momento da visita. Conclusão: Conhecer as necessidades dos familiares se faz como uma importante ferramenta de avaliação dos aspectos relacionados ao cuidado prestado e fornece subsídios para implementação de ações que garantam melhor qualidade da assistência ao paciente e a família


Objetivo: Identificar las necesidades de los familiares de personas internadas en una Unidad de Terapia Intensiva (UTI) en el interior del Estado de Paraná. Método: Los datos fueron recolectados en el período de mayo a septiembre de 2017, por medio de la aplicación del Inventario de Necesidades y Estresores de Familiares en Terapia Intensiva (INEFTI) a 55 familiares. Realizado análisis descriptivo e inferencial. Resultados: Las necesidades más valoradas fueron las relacionadas con información, seguridad en saber que el familiar está recibiendo el mejor tratamiento y de tener acceso/posibilidad de poder conversar con el médico en el momento de la visita. Conclusión: Conocer las necesidades de los familiares se hace como una importante herramienta de evaluación de los aspectos relacionados al cuidado prestado y proporciona subsidios para implementación de acciones que garanticen mejor calidad de la asistencia al paciente y la familia


Assuntos
Humanos , Masculino , Feminino , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Família/psicologia , Avaliação das Necessidades/tendências , Avaliação das Necessidades/estatística & dados numéricos , Enfermagem Familiar/tendências , Unidades de Terapia Intensiva
10.
Dalton Trans ; 47(39): 13861-13869, 2018 Oct 09.
Artigo em Inglês | MEDLINE | ID: mdl-30225486

RESUMO

Cyrhetrenyl aldehyde derivatives [(η5-C5H4CHO)Re(CO)2PR3] with R = methyl (Me, 2a), phenyl (Ph, 2b), and cyclohexyl (Cy, 2c) were synthesized by a photochemical reaction from the starting material [(η5-C5H4CHO)Re(CO)3] (1) and the corresponding phosphines. The complexes were fully characterized by FT-IR, 1H, 13C and 31P NMR spectroscopy, elemental analysis and mass spectrometry. The molecular structures of 2a-c have also been determined. Electronic structure calculations by TD-DFT and electrochemical studies are in sound agreement with the effect of the substitution of one carbonyl group by a phosphine ligand. Additionally, the antiproliferative activity of complexes 1 and 2a-c was studied on the human cancer cell lines HT-29 and PT-45 using an MTT assay. Out of all new compounds, only the triphenylphosphine derivative 2b exhibited pronounced cytotoxic effects on both cell lines, being ca. 1.5 times more potent than cisplatin.


Assuntos
Aldeídos/química , Antineoplásicos/síntese química , Antineoplásicos/farmacologia , Compostos Organometálicos/síntese química , Compostos Organometálicos/farmacologia , Fosfinas/química , Rênio/química , Antineoplásicos/química , Técnicas de Química Sintética , Eletroquímica , Células HT29 , Humanos , Ligantes , Modelos Moleculares , Conformação Molecular , Compostos Organometálicos/química , Teoria Quântica , Relação Estrutura-Atividade
11.
Dalton Trans ; 47(4): 1233-1242, 2018 Jan 23.
Artigo em Inglês | MEDLINE | ID: mdl-29299575

RESUMO

Substituted amino-piperazine derivatives were synthesized and used as precursors for the preparation of a series of new organometallic Re(i) imine complexes with the general formula [(η5-C5H4CH[double bond, length as m-dash]N-(CH2)5-Pz-R)Re(CO)3] (Pz-R: -alkyl or aryl piperazine). The piperazine-based ligands were designed to be potential inhibitors of GSK-3ß kinase. All the ligands and complexes were fully characterized and evaluated against the HT-29 and PT-45 cancer cell lines, in which GSK-3ß plays a crucial role. In this context, we carried out biological evaluation using the MTT colorimetric assay. In terms of structure activity relationship, our findings indicated improved biological activity when aromaticity increased in the organic ligands (3d). In addition, the presence of the rhenium fragment in the imines (5a-d) leads to better activity with IC50 values in the range of 25-100 µM. In addition, our experimental studies were complemented by computational studies, where the volume and electrostatic surface of the organic ligands and organometallic compounds as well as their binding to the kinase protein are calculated.


Assuntos
Glicogênio Sintase Quinase 3 beta/metabolismo , Iminas/química , Compostos Organometálicos/síntese química , Compostos Organometálicos/metabolismo , Rênio/química , Técnicas de Química Sintética , Glicogênio Sintase Quinase 3 beta/química , Células HT29 , Humanos , Ligantes , Modelos Moleculares , Compostos Organometálicos/química , Conformação Proteica
12.
J Phys Chem A ; 120(47): 9363-9369, 2016 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-27805406

RESUMO

The pulse radiolysis method was used to investigate reactions between organometallic chalcones derived from ferrocene, cyrhetrene, and cymantrene substituted with a phenyl (R1) or a 4'-benzo-15-crown-5 (B1) moiety and the solvated electron e-sol and two radicals. The principal spectroscopic transformations resolved with the e-sol reactions reveal that the chalcone compounds react under a diffusion controlled condition. The chromophore in the reaction product is the radical anion chalcone, -C(═O)CH═CH-. The kinetics of the redox processes are consistent with the formation of the radical anion in a first step, followed by an E/Z isomerization reaction in the second step. The rate of the E/Z isomerization reaction is dependent on the chalcone substituent. Reactions with C·H2OH and C·H2Cl radicals are strongly affected by the nature of the organometallic fragment. The transient spectra for the reactions between C·H2OH and C·H2Cl radicals with the phenyl-substituted chalcone show weak, broad absorption bands at λob < 400 nm. Only the ferrocenyl derivatives showed an intense absorption band with λmax = 350 nm. The C-centered radicals react with organometallic chalcones with lifetimes less than or equal to a few microseconds, and the products are assigned as adducts of the C-centered radicals to the chalcone.

13.
Talanta ; 85(5): 2316-9, 2011 Oct 15.
Artigo em Inglês | MEDLINE | ID: mdl-21962648

RESUMO

A sensitive procedure is presented for the voltammetric determination of nickel. The procedure involves an adsorptive accumulation of nickel 1-nitroso-2-napthol (NN) complex on a bismuth film electrode prepared ex situ by electrodeposition. The most suitable operating conditions and parameters such as pH, ligand concentration (C(NN)), adsorptive potential (E(ads)), adsorptive time (t(ads)), scan rate and others were selected and the determination of nickel in aqueous solutions using the standard addition method was possible. The adsorbed Ni-NN complex gives a well defined cathodic stripping peak current at -0.70 V, which was used for the determination of nickel in the concentration range of 10.0-70.0 µg L(-1) (pH 7.5; C(NN) 6.5 µmol L(-1); E(ads) -0.30 V; t(ads) 60s) with a detection limit of 0.1 µg L(-1). The relative standard deviation for a solution containing 10.0 µg L(-1) of Ni(II) was 3.5% (n=4). The proposed method was validated determining Ni(II) in certified reference waste water (SPS-WW1) and Certified Reference Water for Trace Elements (TMDA 51.3) with satisfactory results. Then lake water samples were analyzed.

14.
Dalton Trans ; 39(27): 6295-301, 2010 Jul 21.
Artigo em Inglês | MEDLINE | ID: mdl-20523920

RESUMO

The new rhenium complexes (eta(5)-C(5)H(4)PPh(2))Re(CO)(2)(PR(3)) (R = Me (1) and OMe (2)) were prepared photochemically from (eta(5)-C(5)H(4)PPh(2))Re(CO)(3) in the presence of PMe(3) or P(OMe)(3). Further reaction of these ligands with PdCl(2)(NCPh)(2) in chloroform, produces the heterobimetallic complexes (CO)(2)(PMe(3))(eta(5)-C(5)H(4)PPh(2))Re-PdCl(2) (3) and (CO)(2)(P(OMe)(3))(eta(5)-C(5)H(4)PPh(2))Re-PdCl(2) (4). IR spectroscopy reveals that both complexes possess a Re-Pd interaction which was confirmed by X-ray crystallography (Re-Pd bond distance = 2.762 A in and 2.774 A in ). Relativistic functional density theory calculations have also been carried out in order to probe the bonding in these compounds.

15.
Dalton Trans ; (16): 3044-51, 2009 Apr 28.
Artigo em Inglês | MEDLINE | ID: mdl-19352533

RESUMO

The fulvene complex (eta(6)-C(5)Me(4)CH(2))Re(C(6)F(5))(CO)(2) reacts at the exocyclic methylene carbon with potassium diphenylphosphide to yield the anionic species [(eta(5)-C(5)Me(4)CH(2)PPh(2))Re(C(6)F(5))(CO)(2)](-) (). Protonation of with HCl at 0 degrees C produces the hydride complex trans-(eta(5)-C(5)Me(4)CH(2)PPh(2))Re(C(6)F(5))(H)(CO)(2) (). Thermolysis of a hexanes solution of , under nitrogen atmosphere, produces the chelated complex (eta(5):eta(1)-C(5)Me(4)CH(2)PPh(2))Re(CO)(2) () in good yield. The thermolysis under a CO atmosphere affords a mixture of the complexes (eta(5):eta(1)-C(5)Me(4)CH(2)PPh(2))Re(CO)(2) () and (eta(5)-C(5)Me(4)CH(2)PPh(2))Re(CO)(3) (). The reaction of with two electron donor ligands yields (eta(5)-C(5)Me(4)CH(2)PPh(2))Re(CO)(2)(L) (, L = CO; , L = PMe(3); , L = (t)BuNC). Complex also reacts with I(2), HBF(4) and MeOTf to yield the cationic compounds trans-[(eta(5):eta(1)-C(5)Me(4)CH(2)PPh(2))Re(R)(CO)(2)](+) (, R = I; , R = H; , R = Me). Upon treatment with chloroform, the hydride complex converts to the corresponding chloro derivative . The trans stereochemistry for complexes have been assigned on basis of nu(CO) IR intensities and (13)C-NMR chemical shifts. The reaction of the cationic complexes (, ) with KI and Me(3)NO.2H(2)O yields the neutral species cis-(eta(5):eta(1)-C(5)Me(4)CH(2)PPh(2))Re(I)(R)(CO) (, R = I, , R = Me). The molecular structure of and have been determined by X-ray crystallography.

16.
Rev. bras. odontol ; 51(6): 45-8, nov.-dez. 1994. ilus, tab
Artigo em Português | LILACS, BBO - Odontologia | ID: lil-159963

RESUMO

A eficiência de um novo aparelho eletrônico (Apit) na determinaçäo do comprimento dentário, foi avaliada clinicamente. Sessenta canais que seriam tratados endodonticamente serviram para a realizaçäo do presente trabalho. Inicialmente os canais foram preenchidos com hipoclorito de sódio a 1 por cento para entäo, proceder-se às medidas com aparelho. Com o instrumento endodôntico na posiçäo determinada pelo aparelho, procedeu-se as tomadas radiográficas pela técnica periapical da bissetriz. Nas imagens radiográficas eram realizadas as medidas das distâncias entre o ápice radicular e a ponta do instrumento, para análise da performance do aparelho. Os resultados obtidos mostraram uma eficiência excelente do aparelho, determinando uma confiabilidade em torno de 98,3 por cento


Assuntos
Humanos , Masculino , Feminino , Odontometria/instrumentação , Tratamento do Canal Radicular/instrumentação , Cavidade Pulpar/anatomia & histologia , Eficiência , Endodontia/instrumentação
17.
Radiol. bras ; 18(3): 199-204, set.-dez. 1985. ilus
Artigo em Português | LILACS | ID: lil-97099

RESUMO

A doença de Engelmann-Camurati é caracterizada pela má nutriçäo, sub-desemvolvimento e hiperostose progressiva e expansäo fusiforme da córtex dos ossos longos. As características clínicas, radiológicas e diagnósticos diferenciais säo discutidos


Assuntos
Humanos , Criança , Feminino , Síndrome de Camurati-Engelmann , Osteocondrodisplasias , Diagnóstico Diferencial , Síndrome de Camurati-Engelmann/diagnóstico , Osteocondrodisplasias/diagnóstico , Síndrome
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