Knowledge about osteoporosis in postmenopausal women undergoing antiresorptive treatment.

UNLABELLED: A good understanding and knowledge of osteoporosis is a prerequisite for the success of preventive measures as well as treatment adherence. OBJECTIVE: To assess knowledge about osteoporosis in postmenopausal women with osteoporosis or osteopenia undergoing antiresorptive treatment. SUBJECTS AND METHODS: A cross-sectional study was based on a sample of 232 postmenopausal women with osteopenia or osteoporosis diagnosed by bone density studies and seen at the Menopause Outpatient Clinic at Caism/Unicamp. Women's knowledge of osteoporosis was assessed by means of the OPQ (Osteoporosis questionnaire), a 20-item questionnaire about osteoporosis in areas of general information, risk factors, consequences and treatment. RESULTS: The average age of the women was 61.6 years (±8.2 years) and the average time since menopause was 16.8 years. The average knowledge score obtained by the OPQ was 3.78. The average score for correct answers was 9.8 points, while the average score for incorrect answers was 6 points and 'don't know' answers was 4.1 points. Bivariate analysis showed the variables most closely associated with greater knowledge: education (p<0.01), reading (p<0.02), socioeconomic status (p<0.03), means of acquiring osteoporosis medication (p<0.02), and absence of comorbidities (p<0.04). On multiple regression analysis, the factors which remained associated with better knowledge were higher education, higher socioeconomic status scores and absence of comorbidities. CONCLUSION: Knowledge of osteoporosis in postmenopausal women diagnosed with the disease was limited. Level of education was a strong predictor of knowledge.

Ability to follow anti-reabsorptive drug treatment in postmenopausal women with reduced bone mass.

OBJECTIVE: Studies show that adherence to osteoporosis treatment and prevention is low, which could interfere with therapeutic response. The aim of this study was to evaluate the ability of women to follow a treatment for osteoporosis with different anti-reabsorptives in relation to the prescribed regimen, dose, indications, and mode of ingestion. METHODS: A cross-sectional study that included postmenopausal women all undergoing medicated treatment because of densitometric diagnosis of osteopenia or osteoporosis was carried out by means of the MedTake questionnaire. A total of 227 women at a menopause clinic were studied. The following were evaluated: sociodemographic characteristics, other illnesses, use of concomitant medication, use of medication for osteoporosis, length of use, and ability to follow the treatment in relation to the prescribed regimen, dose, indication, and mode of ingestion. RESULTS: The ability to follow the treatment as evaluated by the MedTake was below 80% for most of the women. No significant difference was found between the daily or weekly bisphosphonate users and those taking raloxifene. The factors associated with inadequate treatment were the following: being 70 years or older (odds ratio [OR], 5.62; 95% CI, 1.23-25.64), being illiterate (OR, 10.14; 95% CI, 2.14-48.12), use of other medications (OR, 0.33; 95% CI, 0.15-0.76), and shorter length of use of medication for osteoporosis (OR, 5.67; 95% CI, 2.27-14.16). CONCLUSION: The ability to follow a treatment involving different anti-reabsorptive medications for osteoporosis is high relative to mode of ingestion, coingestion, and indication and low in relation to knowledge of the correct dose. Low ability is associated with advanced age, being illiterate, not using other medications, and shorter treatment time.