General outcomes and risk factors for minor and major amputations in Brazil.

Objectives Major and minor amputations are associated with significant rates of mortality. However, little is known about the impact of unplanned redo-amputation during the same hospitalization on outcomes. The objectives of this study were to identify the risk factors associated with in-hospital mortality after both major and minor amputations as well as the results of unplanned redo-amputation on outcome. Methods Retrospective study of 342 consecutive patients who were treated with lower extremity amputation in Brazil between January 2013 and October 2014. Results The in-hospital mortality rate was higher in major compared to minor amputation (25.6% vs. 4.1%; p < 0.0001). Whereas chronic kidney disease, chronic obstructive pulmonary disease, and planned staged amputation predicted in-hospital mortality after major amputation, age, and congestive heart failure predicted mortality after minor amputation. The white blood cell count predicted in-hospital mortality following both major and minor amputation. However, postoperative infection predicted in-hospital mortality only following major amputation. Conclusions In-hospital mortality was high after major amputations. Unplanned redo-amputation was not a predictor of in-hospital mortality after major or minor amputation. Planned staged amputation was associated with reduced survival after major but not minor amputation. Postoperative infection predicted mortality after major amputation. Systemic diseases and postoperative white blood cell were associated with in-hospital mortality. This study suggests a possible link between a pro-inflammatory state and increased in-hospital mortality following amputation.

QUALITY OF LIFE EVALUATION IN CELIAC PATIENTS FROM SOUTHERN BRAZIL.

BACKGROUND: Restrictions imposed by the gluten-free diet generate large changes in the daily habits of the celiac patient, causing a negative impact on quality of life. OBJECTIVE: This study aimed to evaluate the quality of life of patients with celiac disease on a capital in Southern Brazil. METHODS: Patients older than 18 years were included, with confirmed celiac disease for at least 60 days in the period from June to October 2013. A validated questionnaire, with specific questions to assess the patient's quality of life celiac was applied. A total score ranged from 20 to 100 points; the higher the score, worse quality of life. RESULTS: A total of 103 questionnaires were evaluated, 96 (93.2%) female, with average score 56.6±12.35 (28 to 88 points). The comparison between the questionnaire scores and family income was not significant (P=0.139). Patients diagnosed less than 1 year have poorer quality of life than those with more than 10 years (P=0.063). Patients older than 60 years had better quality of life compared with the younger ones (P=0.04). CONCLUSION: There was no association between quality of life and factors such as family income, length of diet and age at diagnosis. Chronological age greater than 60 years has positively influenced the quality of life of celiac patients.

QUALITY OF LIFE EVALUATION IN CELIAC PATIENTS FROM SOUTHERN BRAZIL / Avaliação da qualidade de vida do paciente celíaco do Sul do Brasil

BackgroundRestrictions imposed by the gluten-free diet generate large changes in the daily habits of the celiac patient, causing a negative impact on quality of life.ObjetiveThis study aimed to evaluate the quality of life of patients with celiac disease on a capital in Southern Brazil.MethodsPatients older than 18 years were included, with confirmed celiac disease for at least 60 days in the period from June to October 2013. A validated questionnaire, with specific questions to assess the patient’s quality of life celiac was applied. A total score ranged from 20 to 100 points; the higher the score, worse quality of life.ResultsA total of 103 questionnaires were evaluated, 96 (93.2%) female, with average score 56.6±12.35 (28 to 88 points). The comparison between the questionnaire scores and family income was not significant (P=0.139). Patients diagnosed less than 1 year have poorer quality of life than those with more than 10 years (P=0.063). Patients older than 60 years had better quality of life compared with the younger ones (P=0.04).ConclusionThere was no association between quality of life and factors such as family income, length of diet and age at diagnosis. Chronological age greater than 60 years has positively influenced the quality of life of celiac patients.

ContextoRestrições impostas pela dieta isenta em glúten podem gerar grandes mudanças nos hábitos diários do paciente celíaco, causando um impacto negativo na sua qualidade de vida.ObjetivoEste estudo teve como objetivo avaliar a qualidade de vida de pacientes com doença celíaca, em uma capital do Sul do Brasil.MétodosPacientes maiores de 18 anos foram incluídos, com doença celíaca confirmada há mais de 60 dias, no período de junho a outubro de 2013. Um questionário validado, com perguntas específicas para avaliar a qualidade de vida do paciente celíaco foi aplicado. A pontuação total nesse questionário varia entre 20 a 100 pontos; quanto maior a pontuação, pior a qualidade de vida.ResultadosNo total 103 questionários foram avaliados, sendo 96 (93,2%) do sexo feminino, com pontuação média de 56,6±12,35 (28-88 pontos). A comparação entre os escores do questionário e renda familiar não foi significativa (P=0,139). Pacientes diagnosticados há menos de 1 ano, apresentam pior qualidade de vida do que aqueles com mais de 10 anos (P=0,063). Pacientes com mais de 60 anos apresentaram melhor qualidade de vida em comparação com os mais jovens (P=0,04).ConclusãoNão houve associação entre a qualidade de vida e fatores como renda familiar, tempo de dieta e idade no momento do diagnóstico. A idade cronológica superior a 60 anos influenciou positivamente a qualidade de vida de pacientes celíacos.