RESUMO
The use of ultrasound (US) scanning to assess the muscular function during the reinnervation is a new concept in medicine. The US signs of muscle denervation were thoroughly described in the article. The US muscle monitoring was performed by the complete and partial radial nerve injury in various follow-up periods. Absolute and relative indications for surgery were determined. The comparative characteristics of structural muscular changes, together with the US test for the assessment of the treatment efficacy and nerval and muscular recovery were suggested.
Assuntos
Monitorização Intraoperatória/métodos , Músculo Esquelético/diagnóstico por imagem , Síndromes de Compressão Nervosa/diagnóstico , Síndromes de Compressão Nervosa/cirurgia , Nervo Radial/diagnóstico por imagem , Ultrassonografia/métodos , Feminino , Humanos , Masculino , Músculo Esquelético/lesões , Músculo Esquelético/fisiopatologia , Atrofia Muscular/etiologia , Atrofia Muscular/prevenção & controle , Síndromes de Compressão Nervosa/complicações , Síndromes de Compressão Nervosa/fisiopatologia , Procedimentos Neurocirúrgicos/métodos , Nervo Radial/lesões , Nervo Radial/fisiopatologia , Nervo Radial/cirurgia , Índices de Gravidade do Trauma , Resultado do Tratamento , Extremidade Superior/lesões , Extremidade Superior/inervação , Extremidade Superior/patologiaRESUMO
Basic difficulties of the adequate and precise electrophysiological examination of radial nerve injuries are traditionally conditioned by the impossibility to separate the muscle, isolated from the muscles, innervated by the ulnar or medial nerves. The phenomenon of flexor motor units potentials propagation by the stimulating electroneuromyography and M-flow registration from extensor muscles has been described in literature. To prevent the false interpretation of the examination results, 98 patients with radial nerve injuries were examined using the original program of separate assessment of motor and sensor fibers.
Assuntos
Técnicas de Diagnóstico Neurológico , Eletromiografia/métodos , Músculo Esquelético , Exame Neurológico/métodos , Traumatismos dos Nervos Periféricos/diagnóstico , Nervo Radial , Adolescente , Adulto , Idoso , Feminino , Humanos , Pessoa de Meia-Idade , Músculo Esquelético/lesões , Músculo Esquelético/patologia , Músculo Esquelético/fisiopatologia , Procedimentos Neurocirúrgicos/métodos , Traumatismos dos Nervos Periféricos/etiologia , Traumatismos dos Nervos Periféricos/fisiopatologia , Traumatismos dos Nervos Periféricos/cirurgia , Nervo Radial/lesões , Nervo Radial/patologia , Nervo Radial/fisiopatologia , Nervo Radial/cirurgia , Índices de Gravidade do Trauma , Resultado do Tratamento , Extremidade Superior/lesões , Extremidade Superior/inervação , Extremidade Superior/patologiaRESUMO
The influence of different exposure regimes of low-intensity extremely high-frequency electromagnetic radiation on the growth rate of solid Ehrlich carcinoma in mice has been studied. It was shown that, at an optimum repetition factor of exposure (20 min daily for five consecutive days after the tumor inoculation), there is a clearly pronounced frequency dependence of the antitumor effect. The analysis of experimental data indicates that the mechanisms of antitumor effects of the radiation may be related to the modification of the immune status of the organism. The results obtained show that extremely high-frequency electromagnetic radiation at a proper selection of exposure regimes can result in distinct and stable antitumor effects.
Assuntos
Carcinoma de Ehrlich/radioterapia , Micro-Ondas/uso terapêutico , Animais , Carcinoma de Ehrlich/patologia , Masculino , Camundongos , Transplante de NeoplasiasAssuntos
Anticorpos Catalíticos/imunologia , Autoanticorpos/imunologia , Encefalomielite Autoimune Experimental/imunologia , Esclerose Múltipla/imunologia , Animais , Anticorpos Catalíticos/genética , Autoanticorpos/genética , Biomarcadores/sangue , Encefalomielite Autoimune Experimental/genética , Mapeamento de Epitopos , Humanos , Camundongos , Dados de Sequência Molecular , Esclerose Múltipla/diagnóstico , Esclerose Múltipla/genética , Proteína Básica da Mielina/sangue , Proteína Básica da Mielina/química , Proteína Básica da Mielina/metabolismo , Fragmentos de Peptídeos/sangue , Fragmentos de Peptídeos/química , Fragmentos de Peptídeos/metabolismo , Especificidade por Substrato/imunologiaRESUMO
This article deals with the lycopene of mycelial fungi. It pays special attention to its physical and chemical properties, occurrence in nature, biological functions, and the biotechnology of lycopene production. Data are presented concerning the medically important properties of lycopene and the drug Mycolycopene prepared on its basis. Its prospective use in the therapy of prostate cancers is discussed.
Assuntos
Biotecnologia/métodos , Carotenoides/metabolismo , Carotenoides/farmacologia , Fungos/metabolismo , Animais , Anticarcinógenos/farmacologia , Anticarcinógenos/uso terapêutico , Antioxidantes/farmacologia , Carotenoides/química , Carotenoides/uso terapêutico , Aditivos Alimentares , Fungos/classificação , Fungos/citologia , Licopeno , Masculino , Micélio , Neoplasias Experimentais/prevenção & controle , Oxirredução , Neoplasias da Próstata/prevenção & controle , RatosRESUMO
The paper analyzes endoprosthesis of the knee joint in sequelae of tuberculous gonitis in 19 patients and in 10 patients after nonspecific gonitis. The patients' age was 32 to 73 years. Clinically, all the patients third- and fourth-degree gonarthrosis with significant pain and a 15-25 degrees restriction of articular function. X-ray and computed tomographic data indicated destructive changes in the condyles of the femur and tibia, osteoporosis, cysts and cavities, these are typical residual sequelae of sustained tuberculous gonitis. In all cases, endoprosthesis of the knee joint was made by using Johnson-Johnson and Osteonix prostheses. Clinical and functional assessments showed that excellent and good results were obtained in 17 (58.6%) patients, satisfactory results were seen in 11 (37.9%). In one case there was a poor outcome with fibrous contracture of the knee joint after prior nonspecific gonitis with valgus deformity.
