External urology consultation quality at a third-level public hospital in Mexico.

INTRODUCTION: Patient satisfaction is the degree of conformity with the healthcare they receive. It is real evidence and one of the most important factors in determining the effectiveness and quality of healthcare systems. OBJECTIVE: To identify the quality of care in the Urology outpatient department of a third-level hospital. MATERIALS AND METHODS: The NHS (National Health Service) 2018 quality of care questionnaire with 11 sections, 133 items, and duration of approximately 25min was randomly administered to 250 patients attending Urology outpatients at a third-level public hospital in Mexico. RESULTS: According to responses, 92% (n=230) knew the reason for the consultation. 64.8% (n=162) had a consultation with the same physician by whom they were initially seen. The longest reported hospital wait time before being seen was more than 2h in 29.6% (n=74). As for consultation time, 212 patients responded and the duration was 11-20min in 52.8% (n=112). Finally, 33.2% (n=83) considered the quality of service to be good. CONCLUSIONS: The use of the NHS 2018 survey in the Urology service at a third-level public hospital in Mexico is feasible, since we managed to obtain a significant and continuous improvement in all its indicators which is satisfactory for all.

Prospective study of the modified Atkins diet in adult drug-resistant epilepsy: effectiveness, tolerability, and adherence.

INTRODUCTION: Drug-resistant epilepsy presents high worldwide prevalence and is difficult to control despite the wide variety of available antiepileptic drugs (AED). The modified Atkins diet (MAD) is an additional treatment alternative. Several studies have addressed the use of the ketogenic diet and MAD in children with drug-resistant epilepsy, but insufficient research has been conducted into adults with the same condition. OBJECTIVE: To evaluate the effectiveness and tolerability of, and adherence to, the MAD in adults with drug-resistant epilepsy. MATERIAL AND METHODS: We conducted a 6-month pre-post prospective study at a reference hospital. Patients were prescribed the MAD with limited carbohydrate intake and unlimited fat intake. We conducted clinical and electroencephalographic follow-up according to the relevant guidelines, and assessed adverse effects changes in laboratory findings, and adherence. RESULTS: Thirty-two patients with drug-resistant epilepsy were included in the study. Patients' mean age was 30 years, mean disease progression time was 22 years, and all patients had focal or multifocal epilepsy. Thirty-four percent of patients presented > 50% decreases in overall seizure frequency (P =  .001); seizure control was greater in the first month and subsequently declined. These patients presented weight loss (RR: 7.2; 95% CI, 1.3-39.5; P = .02), good to fair adherence only in the first and third months (RR: 9.4; 95% CI, 0.9-93.6; P = .04 and RR: 0.4; 95% CI, 0.30-0.69; P = .02, respectively). Tolerability data showed that the MAD is safe: adverse effects were minor and short-lived in most cases, with the exception of mild to moderate hyperlipidaemia in one-third of patients. The adherence rate was 50% at the end of the study. CONCLUSIONS: In adults with drug-resistant focal epilepsy, the MAD showed adequate tolerability and moderate but decreasing effectiveness and adherence, probably due to a preference for a carbohydrate-based diet.

Effects of preoperative dexamethasone on postoperative pain, nausea, vomiting and respiratory function in women undergoing conservative breast surgery for cancer: Results of a controlled clinical trial.

The objective was to evaluate whether preoperative administration of dexamethasone improved postoperative nausea and vomiting (PONV), pain and respiratory function tests in women undergoing conservative surgery for breast cancer. This was a controlled clinical trial conducted between June 2013 and October 2014. Eighty patients were evaluated. Patients received a preoperative dose of 8 mg of dexamethasone (n = 40) or placebo (n = 40). The data on PONV and pain intensity was obtained and forced spirometry tests were performed, 1 hr before and at 1, 6, 12 and 24 hr after surgery. Any use of additional analgesic/antiemetic drugs was recorded. Patients were followed until 30 days after surgery for any surgical or medical complications. The pain intensity was lower in the treatment group for all periods; PONV was lower at 6, 12 and 24 hr; Additional analgesics/antiemetics were required less frequently (all p < .05). Both groups exhibited a restrictive ventilatory pattern immediately after surgery, which was reversed in the following hours. However, spirometric values were higher in the dexamethasone group. There were no pulmonary or metabolic complications after surgery. Our conclusions were that dexamethasone significantly reduced the incidences of PONV, pain and improved respiratory parameters, and reduced the need for additional postoperative analgesic and antiemetic drugs.

Double-balloon enteroscopy: Indications, approaches, diagnostic and therapeutic yield, and safety. Early experience at a single center. / Enteroscopia de doble balón: indicaciones, abordajes, eficacia diagnóstica y terapéutica y seguridad. Experiencia temprana de un solo centro.

INTRODUCTION AND AIMS: Double-balloon enteroscopy has been improving the visualization of the entire intestine for more than a decade. It is a complementary method in the study of intestinal diseases that enables biopsies to be taken and treatments to be administered. Our aim was to describe its main indications, insertion routes, diagnostic/therapeutic yield, and complications. MATERIALS AND METHODS: All patients referred to our unit with suspected small bowel pathology were included. The insertion route (oral/anal) was determined through diagnostic suspicion. The variables measured were: insertion route, small bowel examination extent, endoscopic diagnosis/treatment, biopsy/histopathology report, complications, and surgical findings. RESULTS: The study included 28 double-balloon enteroscopies performed on 23 patients, of which 10 were women and 13 were men (mean age of 52.95 years). The oral approach was the most widely used (n=21), the main indication was overt small bowel bleeding (n=16), and the general diagnostic yield was 65.21%. The therapeutic intervention rate was 39.1% and the procedure was effective in all the cases. The most widely used treatment was argon plasma therapy (n=7). The complication rate was 8.6%; one patient presented with low blood pressure due to active bleeding and another had deep mucosal laceration caused by the argon plasma. CONCLUSIONS: Double-balloon enteroscopy is a safe and efficacious method for the study and management of small bowel diseases, with an elevated diagnostic and therapeutic yield.

Body weight changes after adjuvant chemotherapy of patients with breast cancer: results of a Mexican cohort study.

Weight gain is observed in breast cancer patients receiving chemotherapy and is a well-known complication. Several factors that contributing to weight gain have been identified. However, there is a lack of information about factors associated with weight changes following adjuvant chemotherapy. A retrospective cohort of 200 pre- and post-menopausal Mexican patients treated for breast cancer was made. Anthropometric variables were measured before/after treatment. Biomarkers, cellular differentiation and chemotherapy were similar between groups. Weight gain occurred in 85.6% of pre-menopausal and 72.6% of post-menopausal women (p = .03). At the end of chemotherapy, weight and body mass index (BMI) did not differ significantly between pre-menopausal (69.3 ± 12.6 kg; 26.6 ± 4.8 kg/m2 ) and post-menopausal women (69.5 ± 10.9 kg; 27.3 ± 4.4 kg/m2 ) (p = .91 and 0.34). Dexamethasone doses were higher in pre-menopausal (85.7 ± 39.1 g) than post-menopausal patients (79.2 ± 22.5 g; p = .13). Weight loss was observed in 9.2% of pre-menopausal and 20.2% of post-menopausal patients (p = .04). A multivariate analysis revealed that age (OR = 2.7; 95% CI = 1.26-5.79; p = .01), menopausal status (OR = 2.29; 95% CI = 1.09-4.80; p = .03), dexamethasone dosage (OR = 2.1; 95% CI = 1.04-4.23; p = .03) and daily caloric intake (OR = 2.3; 95% CI = 1.12-5.10; p = .02) were independent variables that inducted weight gain. Pre- and post-menopausal women gained weight, but more pre-menopausal patients showed gain. An effort should be made to administer lower steroid doses to reduce weight gain.

Manejo y administración de hemoderivados por personal de enfermería en un hospital de segundo nivel / Handling and management of blood-derived products by the nursing staff in a second level hospital

Introducción: El manejo y administración de hemoderivados es una actividad que realiza el personal de enfermería, por lo cual es de gran importancia tener presente que un uso inadecuado de éstos puede tener consecuencias graves en los pacientes, siendo fundamental el buen desempeño del personal de enfermería para la práctica segura. Objetivo: Evaluar el desempeño de enfermería en el manejo y administración de hemoderivados en un hospital de segundo nivel. Métodos: Estudio de diseño transversal. Se incluyeron enfermeras durante el 1º Enero al 30 junio del 2013. Se utilizó un instrumento validado que consta de 4 criterios con 27 ítems de respuestas dicotómicas para identificar el desempeño en el manejo y ministración de hemoderivados. La población fue dividida por categoría contractual. Análisis estadístico: prueba Chi-cuadrada y/ exacta de Fisher. Resultados: Se incluyeron un total de 110 observaciones a personal de enfermería que administró hemoderivados. Se obtuvo un índice de eficiencia global parcial (IEG) parcial a excelente de 64.5%. No se encontró asociación en el turno (p=0.16), servicio (p=0.31) y/o categoría contractual (p=0.25). Los porcentajes de excelente en el IEF fueron bajos (por turno: matutino y nocturno de 10 y 13 respectivamente, medicina interna y cirugía general 5 y 7%, y conforme a la categoría contractual, la enfermera general obtuvo en excelente sólo el 7.5%). Conclusiones: Nuestros resultados nos alertan para implantar programas de capacitación a enfermeras, para otorgar atención de calidad, disminuyendo los riesgos que comprometan la vida del paciente.

Introduction: Handling and managing blood-derived products is a nursing staff activity and thus, it is very important to keep in mind that an inadequate handling of these products can have serious consequences on patients. Therefore, a safe practice from the nursing staff is fundamental. Objective: To assess the nursing performance related to the handling and management of blood-derived products in a second level hospital. Methods: A transversal study design. Nurses were observed from January 1 to June 30, of 2013. A validated instrument with 27 dichotomy-items, and based on 4 criteria, to assess the handling and management of blood-derived products was used. The population was divided by contractual category. Statistical analysis: Chi square and/or Fisher exact test. Results: A total of 110 observations to the nursing staff handling and managing blood-derived products were included. An index of global efficiency (IGE) of partial to excellent of 64.5% was obtained. No associations were found with shift (p=.16), service (p=.31) and/or contractual category (p=.25). The percentages of excellent in the IEF were low (per shift: morning and night of 10 and 13 respectively; per service: internal medicine and general surgery 5 and 7%, and according to the contractual category, overall excellent nurse obtained only 7.5%). Conclusions: Our results encourage us to foster training programs for nurses in order to enhance the quality of care and also decrease the life risks on the patients.

Fibrin glue as adjuvant treatment for gastrocutaneous fistula after gastrostomy tube removal.

Gastrocutaneous fistulas are infrequent after gastrostomy tube removal. However, if the fistulous tract remains permeable, even low-volume output can produce significant cutaneous burns. The use of biodegradable adhesives has been described, where fibrin glue is applied directly over the fistulous tract or under the guidance of procedures such as upper or lower gastrointestinal endoscopy or fistuloscopy. We studied the use of fibrin glue in five consecutive adult patients with gastrocutaneous fistulas after gastrostomy tube removal, with no complications that might impede spontaneous closure. A comparison group included seven patients treated during the preceding 2 years with conservative medical management, who were not treated with fibrin glue. There was no difference between the two groups with regard to age and gender, nor with regard to type of gastrostomy (surgical or endoscopic). The mean output volume from the fistulas was 151.4 +/- 146.1 ml/24 h in the study group and 115.0 +/- 42.7 ml/24 h in the control group, which was not significantly different ( P = 0.80). The duration of previous conservative treatment was 93.8 +/- 85.1 days for the study group and 95.8 +/- 80.7 days for the control group and this also did not differ significantly ( P = 0.93). The time to achieve total fistula closure was 7.0 +/- 3.1 days in the study group and 32.7 +/- 15.7 days in the control group. This difference was statistically significant ( P < 0.004). The time required before oral feeding could be recommenced after spontaneous or induced closure was similar in the two groups, at 2.8 +/- 1.3 days and 4.71 +/- 2.36 days, respectively. Endoscopic guidance allows direct instillation of fibrin glue via the external opening through the whole fistulous tract. This procedure reduces the time required for the closure of gastrocutaneous fistulas.

Complications of central venous catheters.

Central vein catheterization is frequently employed for monitoring, administration of drugs and parenteral nutrition in a variety of medical and surgical illnesses. Despite the widespread use of central vein access, both catheter-related infections and mechanical complications remain unacceptably common. In the last few years, data have become available to show that technical innovations and catheter maintenance protocols can reduce both catheter related bloodstream infections as well as mechanical complications. Future developments should be aimed at both educational intervention and biomaterials research. The former incorporates case-based instruction, problem-solving examination, and database analysis; while the latter will probably lead to a new set of catheters that are more resistant to infection and thrombosis.

Effects of behavior-modifying education in the metabolic profile of the type 2 diabetes mellitus patient.

To demonstrate the advantages of behavior-modifying education in the metabolic profile of the type-2 diabetes mellitus patient. A quasi-experimental study was performed with a control group. The experimental group was made up of 25 type-2 diabetic patients and the control group consisted of 24. The type of education carried out was a behavior modification. Baseline measurements and subsequent monthly measurements of serum glucose, total cholesterol and triglycerides were carried out during 9 months after the intervention. The groups were controlled according to age and sex. The statistical analysis was performed using the Student's and Wilcoxon's test to determine the difference. The experimental group in comparison with the control group in the measurement after the intervention achieved a mean difference in serum glucose of 64.2 mg/dl (p=0.001), in the cholesterol of 31.6 (p=0.008), and in the triglycerides of 50.8 (p=0.006). The behavior-modifying education is a better option than traditional intervention for metabolic control in type-2 diabetes mellitus patients.

[Efficient use of the operating room]. / Uso eficiente del quirófano.

BACKGROUND: To know whether the operating room is efficient requires continual evaluation of the equipment, the competency of personnel included and the level of complexity of the surgical procedures. This evaluation is in the institutional hospital center. The centers. The centers use them for internal control. However, they are slightly or not at all going in the productivity analysis of the operating room for decision making. OBJECTIVE: To identify the elements that favor suboptimal use of operating rooms and in each case, to propose solution for more efficient use. TYPE OF STUDY: Prospective, observational, transversal and comparative. MATERIAL AND METHODS: The study was carried out means of structured questionnaires with the times for surgical interventions in two operating rooms over sixty days. They were conducted the gynecology and general surgery areas. We compared real times against ideal times, and also the complexity levels. STATISTICAL ANALYSIS: Fisher's test p < 0.05 was considerate significant. RESULTS: One hundred and twenty-five surgical procedure were performed, 57.6% during the morning shift (MS) and 42.2% during the evening shift (ES). A total of 66.4% corresponded to complexity level IIII, 84.8% were elective surgeries, 58.4% corresponded to general surgeries, and 41.6% to gynecologic surgical interventions. The delay in times entering the operating room was 20.5 min in MS compared to 4.3 min in ES p < 0.05. In more complex procedures, we found greater delay in surgical time. CONCLUSIONS: The efficient use of the operating room depends on the complying of specific functions in the programmed time of the surgical equipment involved, systematic supervision, and the complexity level.

[Abdominal complications after cardiopulmonary procedures]. / Complicaciones abdominales consecutivas a derivación cardiopulmonar.

OBJECTIVE: To know the frequency of intraabdominal complications and its impact on survival of patients submitted to cardiopulmonary bypass for common open-heart surgical procedures. BACKGROUND: The gastrointestinal complications after cardiac surgery with cardiopulmonary bypass (CPB) have an incidence of 0.3 to 3% but mortality can exceed 60%. Despite improvements in preoperative, operative and postoperative care it has been the general impression that abdominal complications remain a significant problem. TYPE OF STUDY: Retrospective case-control study. MATERIAL AND METHODS: Consecutive patients submitted to cardiac surgery with CPB between March 1995 to March 1997 were included. Any gastrointestinal complication was identified as well as its diagnosis, medical or surgical management and mortality. RESULTS: One thousand and three hundred fifty two patients were studied of which 516 (38%) were operated for coronary revascularization, 502 (37%) valvular replacement, 68 (5.2%) a combination of valvular replacement and revascularization, 144 (10.6%) correction of congenital defects and 122 (9.6%) treated of diverse problems. Forty-four patients developed complications (3.3%) and they were, postoperative intestinal ileus in 14 cases (32%), half of them had concomitant hyperamylasemia. Hepatobiliary complications represented 29.5% (13 cases). Ten patients (22.7%) developed peptic ulcer disease complicated with perforation or hemorrhage. Severe acute pancreatitis was observed in two patients as well as two with bowel necrosis. Three patients had complications considered not related to CPB as grade I liver trauma, acute appendicitis and amebic colitis. The mortality was 11/44 (25%). As a control group, 73 patients operated upon over the same time period and on the same days as the study patients were analyzed. The mortality in this group was 5/73 (6.8%). The medical history of peptic ulcer disease (< 0.01) and postoperative hemodynamic unstability (< 0.05), the use of intra-aortic balloon pump (< 0.05) and respiratory failure with prolonged ventilatory support (< 0.05) were separate statistical significant determinants for the development of postoperative abdominal complications. CONCLUSIONS: Factors indicative of or contributing to periods of decreased end-organ perfusion appear to be significantly related to abdominal complications. Also, medical history of peptic ulcer disease represented an individual determinant of severe surgical complications as ulcer perforation and massive bleeding.

[Hartmann's procedure. Institutional experience with 92 consecutive cases]. / Operación de Hartmann. Experiencia institucional de 92 casos consecutivos.

BACKGROUND: Since it's description in 1923, Hartmann's procedure is widely used for the surgical treatment of acute left colonic complications when preoperative bowel lavage is not feasible and/or there is high risk of anastomotic dehiscence. OBJECTIVE: Analyze the results of Hartmann's operation in the surgical treatment of consecutive patients at a single institution during a 30-month interval. TYPE OF STUDY: Prospective, non-randomized and longitudinal study. MATERIAL AND METHODS: Patients treated with the Hartmann procedure between March 1995 and September 1998. Surgical indication, intraoperative findings, morbidity and mortality were analyzed as well as the rate of reestablishment of bowel continuity and it's morbimortality. RESULTS: Ninety-two patients underwent a Hartmann procedure. The mean patient's age was 60 +/- 25 years (range of 21 to 88 years) and 60% were older than 65 years. An emergency operation was carried out in 91% of the cases. Most of the patients had intra-abdominal sepsis (56%) and benign colonic process (83%). The morbidity rate was 34% and mortality rate 19. During follow-up the bowel continuity was reestablished in 32% of the cases without fatalities. CONCLUSIONS: Hartmann's procedure is a good option for non-elective surgical treatment complicated rectosigmoid pathology. The morbidity and mortality of the operation are highly dependent on the degree of preoperative sepsis and the patient's preexisting condition. The rate of reestablishment of bowel continuity was low probably because of short follow-up.

Retained foreign bodies following intra-abdominal surgery.

BACKGROUND/AIMS: A retained foreign body in the abdominal cavity following surgery is a continuing problem. Despite precautions, the incidence is grossly underestimated. The purpose of this study is to report the result of surgical treatment on 24 consecutive cases treated by the authors during a 10-year period. METHODOLOGY: All consecutive patients with a confirmed diagnosis of foreign body after abdominal surgery were studied. Data collected included the patients' age and sex, the initial diagnosis and primary surgical treatment, period of time between the probable causative operation and the definitive treatment, nature of the foreign body, clinical presentation, predisposing factors, and diagnosis and management; morbidity and mortality are presented as well as guidelines for prevention. RESULTS: All patients were symptomatic. Eight patients presented as intraabdominal sepsis (4 with intestinal obstruction, 4 with entero- or colo-cutaneous fistula), non-specified abdominal pain in 3, persistent sinus and granuloma in 2, abdominal palpable mass in another 2 cases, and 1 patient with vaginal discharge. The diagnosis was established pre-operatively in 15 cases by means of plain abdominal radiographs, ultrasound or computed tomography (CT) scan. Morbidity was observed in 50% and the rate of surgical reinterventions because of fistulas or residual sepsis in 18%. The mortality was almost 10%. CONCLUSIONS: The clinical manifestations ranged from mild abdominal pain, palpable mass, persistent drainage and granuloma to intestinal obstruction secondary to adhesions or occlusion of the intestinal lumen because of migration of the foreign body and intraabdominal sepsis. Despite this being a rare situation, when it happens it presents as a very serious problem to patients with high rates of morbidity and mortality. Prevention remains the key to the problem.

[Comparative study of soft diet or clear liquids in the resumption of oral intake in the postoperative period]. / Análisis comparativo entre reinstalar la vía oral en el postoperatorio con dieta blanda o líquidos claros.

BACKGROUND: The reinstitution of oral intake in patients who have undergone intraabdominal surgery has traditionally progressed in a stepwise fashion beginning with clear liquids, liquid diet and after an adequate tolerance regular diet. OBJECTIVE: To determine if the reinstitution of oral intake after major abdominal surgery with regular diet offers benefits into which it's not harmful for patients and reduce the in-hospital stay. TYPE OF STUDY: Prospective, randomized, open study conducted between October 1996 to May 1997. MATERIAL AND METHODS: Patients aged 18 and older submitted to elective or urgent surgery of the abdomen and pelvis were included with the exception of: bariatric surgery, esophageal resection, pyloroplasty, pancreato-duodenal resection, laparoscopic surgery and patients under ventilatory support or with enteral or parenteral nutrition. As soon as postoperative ileus disappeared patients were randomly assigned to receive regular diet (group 1) or clear liquids (group 2) as the first oral intake. Oral diet tolerance was evaluated as well as the caloric and protein intake, the in-hospital stay and the cost. RESULTS AND MEASUREMENTS: Group 1 was conformed by 63 patients, and group 2 for 69 patients. There was no difference between, sex, age, kind of surgery (elective or emergency) and the type of pathology. 96.6% of patients in group 1 tolerated regular diet and 96.9% of patients in group 2 tolerated clear liquids. Only two patients of each group required oral intake suspension. The in-hospital stay was 2.6 +/- 2.0 days in group 1 against 3.4 +/- 2.6 in group 2 (P = < 0.005), the cost of the in-hospital stay period after the beginning of oral intake was 2726 +/- 2107 pesos in group 1 against 3547 +/- 2690 in group 2 (P = < 0.005), the caloric and protein intake were 1307 +/- 523 Kcals with 55.9 +/- 23.2 grams of proteins in group 1 and 651 +/- 204 Kcals and 0 grams of proteins in group 2 (P = < 0.00001). CONCLUSIONS: No difference was found in adverse reactions with the use of regular diet as the first meal. The in-hospital stay and the cost were reduced significantly and the calories and grams of proteins are higher in group 1. These results suggest that the routine use of clear liquids as the initial postoperative diet may be unnecessary and nutritionally suboptimal when compared with regular diet.

[Spontaneous hemorrhage in liver neoplasms. Experience at an institution]. / Hemorragia espontánea en neoplasias hepáticas. Experiencia de una institución.

OBJECTIVE: Retrospective review of a single Institution experience with the management of hepatic neoplasms complicated with spontaneous bleeding. METHODS: In a 11 years period from 1980 to 1990 we reviewed the medical charts of patients treated at our Institution with the diagnosis of hepatic neoplasms complicated with sudden bleeding. We recorded demographic information, clinical manifestations, treatment and outcome. A review of the world literature was done. RESULTS: We found six patients with the diagnosis of liver tumors complicated with sudden bleeding. Five patients were female with a age range from 30 to 67 years old. Four of them had an adenoma (three of them single and one multiple) and the fifth had a non-parasitic cyst. Seventy-five per cent of the patients with the diagnosis of adenoma had used in the past oral contraceptives for at least three years. The sixth patient was a male with a ruptured hepatocellular carcinoma. Three patients were admitted in shock. Successful transcatheter hepatic arterial embolization was performed in two patients; the third required operative hemostasis. Major hepatic resections were performed in three patients including a total hepatectomy and liver transplant. All patients recovered satisfactorily. CONCLUSIONS: The spontaneous rupture of benign and malignant tumors of the liver is not a common phenomenon, but is a serious complication. The experience of our Institution and the reports of literature favor CT scan and arteriogram as the most effective diagnostic methods in this group of patients, but arteriogram has the advantage of its therapeutic potential. The long term prognosis of this patients depends of their pathological diagnosis.

Colecistitis aguda acalculosa en el paciente con trauma grave / Acute acalculous cholecistitis in severe trauma patients

Antecedentes: La frecuencia informada de CAA en pacientes con lesiones traumáticas oscila entre 0.5 y 5 por ciento, con una mortalidad que varía entre 7 y 75 por ciento, valores determinados por reporte de casos o series retrospectivas. Objetivo: Determinar la frecuencia de colecistitis aguda acalculosa (CAA) en una población de pacientes con trauma contuso grave y las implicaciones clínicas que tiene, así como los factores de riesgo que puedan precipitar su aparición, evaluación de cambios morfológicos tempranos, tratamiento quirúrgico y morbi-mortalidad. Pacientes y métodos: Estudio prospectivo, observacional, longitudinal y descriptivo inferencial conducido entre ocubre de 1994 y junio de 1995. Se incluyeron 28 pacientes adultos consecutivos con trauma contuso al menos en dos regiones corporales. Se estimó la severidad de las lesiones con una escala fisiológica (Revised Trauma Score = RTS) y una anatómica (Injury Severity Score = ISS). Todos los pacientes se sometieron a ultrasonido de hígado y vías biliares a su ingreso y cada 5 a 7 días para la detección temprana de cambios sonográficos o concluyentes de CAA. Cada paciente recibió tratamiento conveniente de acuerdo a sus lesiones. La evaluación fue clínica, laboratorial y de los posibles factores de riesgo para el desarrollo de esta alteración. Mediciones: Prueba exacta de Fisher de dos colas para las variables cualitativas y prueba U de Mann-Withney para las cuantitativas. Resultados: Del total 21 correspondieron al sexo masculino (75 por ciento) y 7 al femenino (25 por ciento) con un promedio de edad de 45.5 años y un período de observación promedio de 22.5 días. Siete de los pacientes (25 por ciento) desarrollaron cambios sonográficos a partir del noveno día de manejo, 4 fueron concluyentes de CAA demostrados histológicamente, de los cuales tres se sometieron a colecistectornía abierta sin morbilidad y mortalidad y mejoría de sus condiciones clínicas. El otro caso falleció por hipovolemia sin ofrecerle tratamiento quirúrgico. Los factores de riesgo con significancia estadística fueron: Estancia prolongada, fiebre, dolor abdominal, evaluación de la fosfatasa alcalina, hipoalbuminemia, uso de nutrición parenteral total y casos complicados con neumonía intrahospitalaria (P = < 0.05). Hubo significancia marginal con el uso de analgesia-sedación. La mortalidad global fue del 18 por ciento. Conclusiones: La frecuencia es mayor a la informada previamente y no hubo mortalidad relacionada a la presencia de la CAA. El ultrasonido detecta fácilmente los cambios morfológicos vesiculares. No hubo morbilidad y mortalidad atribuida a la colecistectomía.

[Acute acalculous cholecystitis in patients with severe trauma]. / Colecistitis aguda acalculosa en el paciente con trauma grave.

BACKGROUND: The incidence of AAC on patients with traumatic lesions fluctuates between 0.5 to 5%, with mortality which varies between 7 and 75%. These values are determined by case reports or retrospective series. AIM: To determine the incidence of acute acalculous cholecystitis (AAC) in a number of patients with severe trauma and its clinical implications, as well as the risk factors that can favour the development of this pathology, evaluation of early morphological changes, surgical treatment and morbidity and mortality. PATIENTS AND METHODS: Prospective, observational, longitudinal and descriptive inferential study conducted from October 1994 to June 1995. Twenty eight consecutive adult patients with contusion severe trauma on at least two corporal regions were included. The severity of lesions was estimated with a physiologic scale (Revised Trauma Score = RTS) and an anatomic one (Injury Severity Score = ISS). All patients were submitted to ultrasound of the liver and biliary tract on their admittance and every 5 or 7 days for an early detection of sonographic changes or conclusive of AAC. Each patient was treated conveniently in accordance with his or her lesions. The patients were evaluated clinically, with laboratory exams, and for possible risk factors for the development of this pathology. MEASUREMENTS: Two Tailed Fisher's Exact Test for qualitative variables and Mann-Withney U Test for the quantitatives. RESULTS: Twenty one patients were male (75%) and 7 were female (25%), average age 45.5 years and an average observation period of 22.5 days. Seven of these patients (25%) developed sonographic changes starting the 9th day after admission, 4 were conclusive of AAC proved histologically, three of these underwent open cholecystectomy with no morbidity and mortality and improvement of their clinical conditions. The other patient died due to hypovolemia without having been offered surgical treatment. The risks factors with statistical significance were: Long in-hospital stay, fever, abdominal pain, elevation of alkaline phosphatase, hypoalbuminemia, use of parenteral nutritional support and nosocomial pneumonia (P = < 0.05). There was a marginal significance with the use of sedatives and analgesics. Global mortality was 18%. CONCLUSIONS: The incidence is more than the one previously informed and there was no mortality related the presence of AAC. The ultrasound easily detects the gallbladder morphological changes. There was no morbidity or mortality due to the cholecystectomy.

Comparison of outcomes and complications for open and laparoscopic cholecystectomy in Mexico.

A retrospective analysis of the outcome and surgical complications of two groups of patients undergoing cholecystectomy was performed. Group I consisted of 253 patients who underwent laparoscopic cholecystectomy between 1991 and 1994, and group II was formed by 292 patients who met the same preoperative criteria than patients of group I and underwent open cholecystectomy between 1986 and 1990, prior to the introduction of laparoscopic cholecystectomy in our hospital. General characteristics and associated clinical conditions were similar for both groups. Intraoperative cholangiography was used more frequently in group II whereas preoperative ERCP was performed more frequently in group I patients. There was no operative mortality in any of the groups. There were no statistically significant differences between both groups in terms of type and number of complications.