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1.
Neurología (Barc., Ed. impr.) ; 35(9): 621-627, nov.-dic. 2020. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-192754

RESUMO

INTRODUCCIÓN: Nos proponemos analizar las complicaciones neurológicas de los pacientes con infección grave por SARS-CoV-2 que han requerido ingreso en unidad de cuidados intensivos (UCI). PACIENTES Y MÉTODOS: Estudio descriptivo retrospectivo, observacional, de pacientes consecutivos ingresados en UCI por infección respiratoria grave por SARS-CoV-2 desde el 1 de abril hasta el 1 de junio de 2020. RESULTADOS: Registramos 30 pacientes con síntomas neurológicos, 21 hombres (72,40%), edad media: 57,41 años ± 11,61 desviación estándar (DE). Estancia media en UCI: 18,83 ± 14,33 DE. A nivel sindrómico: 28 pacientes (93,33%) con síndrome confusional agudo, 15 (50%) con patología neuromuscular, 5 (16,66%) con cefalea, 4 (13,33%) con patología cerebrovascular y 4 (13,33%) con encefalopatías/encefalitis. Punción lumbar normal en 6 pacientes (20%). La RMN craneal o TAC craneal mostró alteraciones en 20 casos (66,6%). Se realizó EEG en todos los pacientes (100%), alterado en 8 pacientes (26,66%). En 5 de los 15 pacientes con miopatía clínica se ha podido confirmar con ENMG. Hemos encontrado relación entre la mayor edad y los días de ingreso en UCI (p = 0,002; IC95%: 4,032-6,022; OR: 3,594). CONCLUSIONES: La infección grave por COVID-19 afecta mayoritariamente a hombres, similar a lo descrito en otras series. La mitad de nuestros pacientes presenta una miopatía aguda, y casi la totalidad de los pacientes salen de la UCI con síndromes confusionales agudos que evolucionan a una resolución completa, sin correlacionarse con los resultados del EEG o de pruebas de neuroimagen. La mayor edad se asocia con un mayor número de días de estancia en UCI


INTRODUCTION: We analysed the neurological complications of patients with severe SARS-CoV-2 infection who required intensive care unit (ICU) admission. PATIENTS AND METHODS: We conducted a retrospective, observational, descriptive study of consecutive patients admitted to the ICU due to severe respiratory symptoms secondary to SARS-CoV-2 infection between 1 April and 1 June 2020. RESULTS: We included 30 patients with neurological symptoms; 21 were men (72.40%), and mean age (standard deviation [SD]) was 57.41 years (11.61). The mean duration of ICU stay was 18.83 days (14.33). The neurological conditions recorded were acute confusional syndrome in 28 patients (93.33%), neuromuscular disease in 15 (50%), headache in 5 (16.66%), cerebrovascular disease in 4 (13.33%), and encephalopathies/encephalitis in 4 (13.33%). CSF analysis results were normal in 6 patients (20%). Brain MRI or head CT showed alterations in 20 patients (66.6%). EEG was performed in all patients (100%), with 8 (26.66%) showing abnormal findings. In 5 of the 15 patients with clinical myopathy, diagnosis was confirmed with electroneuromyography. We found a correlation between older age and duration of ICU stay (P = .002; 95%CI: 4.032-6.022; OR: 3,594). CONCLUSIONS: Severe COVID-19 mainly affects men, as observed in other series. Half of our patients presented acute myopathy, and almost all patients left the ICU with acute confusional syndrome, which fully resolved; no correlation was found with EEG or neuroimaging findings. Older age is associated with longer ICU stay


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Infecções por Coronavirus/complicações , Pneumonia Viral/complicações , Pandemias , Doenças do Sistema Nervoso/virologia , Doenças do Sistema Nervoso/diagnóstico por imagem , Estado Terminal , Índice de Gravidade de Doença , Tomografia Computadorizada por Raios X , Estudos Retrospectivos
2.
Neurologia (Engl Ed) ; 35(9): 621-627, 2020.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-32912745

RESUMO

INTRODUCTION: We analysed the neurological complications of patients with severe SARS-CoV-2 infection who required intensive care unit (ICU) admission. PATIENTS AND METHODS: We conducted a retrospective, observational, descriptive study of consecutive patients admitted to the ICU due to severe respiratory symptoms secondary to SARS-CoV-2 infection between 1 April and 1 June 2020. RESULTS: We included 30 patients with neurological symptoms; 21 were men (72.40%), and mean age (standard deviation [SD]) was 57.41 years (11.61). The mean duration of ICU stay was 18.83 days (14.33). The neurological conditions recorded were acute confusional syndrome in 28 patients (93.33%), neuromuscular disease in 15 (50%), headache in 5 (16.66%), cerebrovascular disease in 4 (13.33%), and encephalopathies/encephalitis in 4 (13.33%). CSF analysis results were normal in 6 patients (20%). Brain MRI or head CT showed alterations in 20 patients (66.6%). EEG was performed in all patients (100%), with 8 (26.66%) showing abnormal findings. In 5 of the 15 patients with clinical myopathy, diagnosis was confirmed with electroneuromyography. We found a correlation between older age and duration of ICU stay (P=.002; 95%CI: 4.032-6.022; OR: 3,594). CONCLUSIONS: Severe COVID-19 mainly affects men, as observed in other series. Half of our patients presented acute myopathy, and almost all patients left the ICU with acute confusional syndrome, which fully resolved; no correlation was found with EEG or neuroimaging findings. Older age is associated with longer ICU stay.


Assuntos
Betacoronavirus , Infecções por Coronavirus/complicações , Estado Terminal , Doenças Musculares/etiologia , Doenças do Sistema Nervoso/etiologia , Pandemias , Pneumonia Viral/complicações , Doença Aguda , Adulto , Fatores Etários , Idoso , COVID-19 , Hemorragia Cerebral/diagnóstico por imagem , Hemorragia Cerebral/epidemiologia , Hemorragia Cerebral/etiologia , Confusão/epidemiologia , Confusão/etiologia , Infecções por Coronavirus/epidemiologia , Cuidados Críticos , Feminino , Humanos , Tempo de Internação/estatística & dados numéricos , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Doenças Musculares/epidemiologia , Doenças do Sistema Nervoso/epidemiologia , Neuroimagem , Pneumonia Viral/epidemiologia , Estudos Retrospectivos , SARS-CoV-2 , Espanha/epidemiologia
3.
Neurologia ; 35(9): 621-627, 2020.
Artigo em Espanhol | MEDLINE | ID: mdl-38620654

RESUMO

Introduction: We analysed the neurological complications of patients with severe SARS-CoV-2 infection who required intensive care unit (ICU) admission. Patients and methods: We conducted a retrospective, observational, descriptive study of consecutive patients admitted to the ICU due to severe respiratory symptoms secondary to SARS-CoV-2 infection between 1 April and 1 June 2020. Results: We included 30 patients with neurological symptoms; 21 were men (72.40%), and mean age (standard deviation [SD]) was 57.41 years (11.61). The mean duration of ICU stay was 18.83 days (14.33). The neurological conditions recorded were acute confusional syndrome in 28 patients (93.33%), neuromuscular disease in 15 (50%), headache in 5 (16.66%), cerebrovascular disease in 4 (13.33%), and encephalopathies/encephalitis in 4 (13.33%). CSF analysis results were normal in 6 patients (20%). Brain MRI or head CT showed alterations in 20 patients (66.6%). EEG was performed in all patients (100%), with 8 (26.66%) showing abnormal findings. In 5 of the 15 patients with clinical myopathy, diagnosis was confirmed with electroneuromyography. We found a correlation between older age and duration of ICU stay (P = .002; 95% CI: 4.032-6.022; OR: 3,594). Conclusions: Severe COVID-19 mainly affects men, as observed in other series. Half of our patients presented acute myopathy, and almost all patients left the ICU with acute confusional syndrome, which fully resolved; no correlation was found with EEG or neuroimaging findings. Older age is associated with longer ICU stay.

4.
Rehabilitación (Madr., Ed. impr.) ; 35(3): 159-165, mayo 2001.
Artigo em Es | IBECS | ID: ibc-526

RESUMO

Introducción: El objetivo de este estudio ha sido valorar las patologías y las características demográficas de la población atendida en la urgencia del Servicio de Rehabilitación del Hospital de Rehabilitación y Traumatología (HRT) del Hospital Universitario La Paz de Madrid. Los facultativos de este Servicio atienden a los pacientes que acuden a urgencias y que no han sufrido traumatismo previo.Pacientes y métodos: De manera aleatoria se eligió un mes del año (noviembre 1999) y se procedió a la revisión de todas las historias clínicas de pacientes evaluados en urgencias por médicos rehabilitadores. En total sumaron 1.284 registros. De ellos se recogieron datos administrativos (fecha, hora de asistencia,...), demográficos (edad, sexo) y de asistencia médica (diagnóstico). Para el manejo de los datos se utilizaron los programas Ms Excel 97® y SAS®.Resultados: De los 1.284 pacientes (un 5 por ciento del total de urgencias del centro), un 62 por ciento eran mujeres. La mediana de edad fue de 42 años, con un rango desde 95 hasta tres años. La mayor parte de la población se incluía dentro del grupo de 25-45 años de edad (26,5 por ciento). Los días más frecuentados fueron lunes (18,5 por ciento), martes (15,5 por ciento) y domingos (14,8 por ciento), con una media diaria de asistencia de 42,8 pacientes/día (rango 26 hasta 57). Las patologías más frecuentemente atendidas fueron las relativas a columna dorsolumbar (25 por ciento), cervical (15,7 por ciento), rodilla (12,6 por ciento), hombro (8,2 por ciento) y muñeca (7,5 por ciento). En cuanto al tiempo de evolución, el 41 por ciento acudía a urgencias en los tres primeros días de dolor, mientras que un 13,6 por ciento presentaba sintomatología de más de un mes de evolución al acudir a urgencias. Las horas de mayor afluencia coinciden con aquellas en que los ambulatorios y centros de atención primaria mantienen actividad asistencial, incluso de urgencias de área (9 a 19 horas).Conclusión: Los dolores osteomusculares sin claro origen traumático suponen una importante carga asistencial de las urgencias de un gran hospital. Con gran frecuencia los pacientes prefieren acudir a la urgencia del hospital como primera visita en vez de a las consultas de los centros de atención primaria o a las urgencias de área. La educación sanitaria debería ser fundamental para solucionar esta sobrecarga asistencial (AU)


Assuntos
Serviços Médicos de Emergência , Reabilitação , Epidemiologia
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