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1.
Sci Rep ; 11(1): 20739, 2021 10 20.
Artigo em Inglês | MEDLINE | ID: mdl-34671103

RESUMO

Since the first coronavirus disease 2019 (COVID-19) outbreak appeared in Wuhan, mainland China on December 31, 2019, the geographical spread of the epidemic was swift. Malaysia is one of the countries that were hit substantially by the outbreak, particularly in the second wave. This study aims to simulate the infectious trend and trajectory of COVID-19 to understand the severity of the disease and determine the approximate number of days required for the trend to decline. The number of confirmed positive infectious cases [as reported by Ministry of Health, Malaysia (MOH)] were used from January 25, 2020 to March 31, 2020. This study simulated the infectious count for the same duration to assess the predictive capability of the Susceptible-Infectious-Recovered (SIR) model. The same model was used to project the simulation trajectory of confirmed positive infectious cases for 80 days from the beginning of the outbreak and extended the trajectory for another 30 days to obtain an overall picture of the severity of the disease in Malaysia. The transmission rate, ß also been utilized to predict the cumulative number of infectious individuals. Using the SIR model, the simulated infectious cases count obtained was not far from the actual count. The simulated trend was able to mimic the actual count and capture the actual spikes approximately. The infectious trajectory simulation for 80 days and the extended trajectory for 110 days depicts that the inclining trend has peaked and ended and will decline towards late April 2020. Furthermore, the predicted cumulative number of infectious individuals tallies with the preparations undertaken by the MOH. The simulation indicates the severity of COVID-19 disease in Malaysia, suggesting a peak of infectiousness in mid-March 2020 and a probable decline in late April 2020. Overall, the study findings indicate that outbreak control measures such as the Movement Control Order (MCO), social distancing and increased hygienic awareness is needed to control the transmission of the outbreak in Malaysia.


Assuntos
COVID-19/epidemiologia , COVID-19/fisiopatologia , Informática em Saúde Pública/métodos , Simulação por Computador , Surtos de Doenças , Suscetibilidade a Doenças/epidemiologia , Epidemias , Humanos , Malásia , Modelos Teóricos , Saúde Pública , Quarentena , SARS-CoV-2
2.
Heliyon ; 7(2): e06048, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33553773

RESUMO

Recent advances in phytochemical analysis have allowed the accumulation of data for crop researchers due to its capacity to footprint and distinguish metabolites that are present within an organisms, tissues or cells. Apart from genotypic traits, slight changes either by biotic or abiotic stimuli will have significant impact on the metabolite abundances and will eventually be observed through physicochemical characteristics. Apposite data mining to interpret the mounds of phytochemical information from such a dynamic system is thus incumbent. In this investigation, several statistical software platforms ranging from exploratory and confirmatory technique of multivariate data analysis from four different statistical tools of COVAIN, SIMCA-P+, MetaboAnalyst and RIKEN Excel Macro were appraised using an oil palm phytochemical data set. As different software tool encompasses its own advantages and limitations, the insights gained from this assessment were documented to enlighten several aspects of functions and suitability for the adaptation of the tools into the oil palm phytochemistry pipeline. This comparative analysis will certainly provide scientists with salient notes on data assessment and data mining that will later allow the depiction of the overall oil palm status in-situ and ex-situ.

3.
Entropy (Basel) ; 22(9)2020 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-33286758

RESUMO

Credit scoring is an important tool used by financial institutions to correctly identify defaulters and non-defaulters. Support Vector Machines (SVM) and Random Forest (RF) are the Artificial Intelligence techniques that have been attracting interest due to their flexibility to account for various data patterns. Both are black-box models which are sensitive to hyperparameter settings. Feature selection can be performed on SVM to enable explanation with the reduced features, whereas feature importance computed by RF can be used for model explanation. The benefits of accuracy and interpretation allow for significant improvement in the area of credit risk and credit scoring. This paper proposes the use of Harmony Search (HS), to form a hybrid HS-SVM to perform feature selection and hyperparameter tuning simultaneously, and a hybrid HS-RF to tune the hyperparameters. A Modified HS (MHS) is also proposed with the main objective to achieve comparable results as the standard HS with a shorter computational time. MHS consists of four main modifications in the standard HS: (i) Elitism selection during memory consideration instead of random selection, (ii) dynamic exploration and exploitation operators in place of the original static operators, (iii) a self-adjusted bandwidth operator, and (iv) inclusion of additional termination criteria to reach faster convergence. Along with parallel computing, MHS effectively reduces the computational time of the proposed hybrid models. The proposed hybrid models are compared with standard statistical models across three different datasets commonly used in credit scoring studies. The computational results show that MHS-RF is most robust in terms of model performance, model explainability and computational time.

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