Hemorragia fetomaterna masiva / Massive feto-maternal haemorrhage

La hemorragia fetomaterna masiva es una entidad con una baja frecuencia y constituye una complicación con elevada morbimortalidad fetal, que suele cursar con una clínica inapreciable y en la que el desarrollo de nuevas técnicas diagnósticas y terapéuticas permitirá vislumbrar un futuro esperanzador. (AU)

Massive fetomaternal hemorrhage: how long should children with good evolution be controlled? A case report.

We report on a term infant with a severe fetomaternal hemorrhage that caused a serious anemia that was surmounted after several transfusions. After the initial complications, such as persistent pulmonary circulation, severe anemia and thrombocytopenia, the outcome was good. We discuss the importance of a long-term follow-up of affected children, as well as their mothers. No clear parameters for a real prognosis are available. A follow-up is needed in order to detect possible complications in neurological development.

[Structural bases of the induction of immune reactions in emotional stress]. / Strukturnye osnovy induktsii immunnykh reaktsii pri émotsional'nom stresse.

Immobilization stress in rats can provoke damages of the brain parenchymal vessels, which are most pronounced in the reticular formation of the midbrain. In this case the blood plasma and cells enter the brain and the blood elements of brain tissue enter the circulation. Some experimental animals exhibit the serum complement-fixing brain antibodies and specific reactions of basophils to brain antigens 14 days after exposure to stress. Most of the rats reveal immune reactions and neurosensitivity a month later. Some of them exhibit the autoantibodies to norepinephrine and serotonin. It is suggested that stress-induced brain vascular damages may play an important role in the mechanisms of immune reaction induction.

[Allergic encephalomyelitis in guinea pigs on the intracutaneous and subcutaneous administration of fragment 114-122 of the human myelin cationic protein]. / Allergicheskii éntsefalomielit u morskikh svinok pri vnutrikozhnom i podkozhnom vvedenii fragmenta 114-122 kationnogo belka mielina cheloveka.

Single intracutaneous injection of 30 micrograms of human basic myelin protein peptide 114-122 (H-Phe-Ser-Trp-Gly-Ala-Glu-Gly-Gln-Arg-OH) with Freund adjuvant induced the onset of encephalomyelitis on day 9-19 after the injection. The lethality was 33%. In autumn the disease was more severe than in summer.