Self-Healing Thiolated Pillar[5]arene Films Containing Moxifloxacin Suppress the Development of Bacterial Biofilms.

Polymer self-healing films containing fragments of pillar[5]arene were obtained for the first time using thiol/disulfide redox cross-linking. These films were characterized by thermogravimetric analysis and differential scanning calorimetry, FTIR spectroscopy, and electron microscopy. The films demonstrated the ability to self-heal through the action of atmospheric oxygen. Using UV-vis, 2D 1H-1H NOESY, and DOSY NMR spectroscopy, the pillar[5]arene was shown to form complexes with the antimicrobial drug moxifloxacin in a 2:1 composition (logK11 = 2.14 and logK12 = 6.20). Films containing moxifloxacin effectively reduced Staphylococcus aureus and Klebsiella pneumoniae biofilms formation on adhesive surfaces.

True Molecular Composites: Unusual Structure and Properties of PDMS-MQ Resin Blends.

Poly(dimethyl siloxane)-MQ rubber molecular composites are easy to prepare, as it does not require a heterophase mixing of ingredients. They are characterized by perfect homogeneity, so they are very promising as rubber materials with controllable functional characteristics. The manuscript reveals that MQ resin particles can significantly, more than by two orders of magnitude, enhance the mechanical properties of poly(dimethyl siloxane), and, as fillers, they are not inferior to aerosils. In the produced materials, MQ particles play a role of the molecular entanglements, so rubber molecular weight and MQ filler concentration are the parameters determining the structure and properties of such composites. Moreover, a need for a saturation of the reactive groups and minimization of the surface energy of MQ particles also determine the size and distribution of the filler at different filler rates. An unusual correlation of the concentration of MQ component and the interparticle spacing was revealed. Based on the extraordinary mechanical properties and structure features, a model of the structure poly(dimethyl siloxane)-rubber molecular composites and of its evolution in the process of stretching, was proposed.

New Principles of Polymer Composite Preparation. MQ Copolymers as an Active Molecular Filler for Polydimethylsiloxane Rubbers.

Colorless transparent vulcanizates of silicone elastomers were prepared by mixing the components in a common solvent followed by solvent removal. We studied the correlation between the mechanical behavior of polydimethylsiloxane (PDMS)-rubber compositions prepared using MQ (mono-(M) and tetra-(Q) functional siloxane) copolymers with different ratios of M and Q parts as a molecular filler. The composition and molecular structure of the original rubber, MQ copolymers, and carboxyl-containing PDMS oligomers were also investigated. The simplicity of the preparation of the compositions, high strength and elongation at break, and their variability within a wide range allows us to consider silicone elastomers as a promising alternative to silicone materials prepared by traditional methods.