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1.
Medicine (Baltimore) ; 103(3): e37010, 2024 Jan 19.
Artigo em Inglês | MEDLINE | ID: mdl-38241532

RESUMO

RATIONALE: Adenoid cystic carcinoma (AdCC) is a rare malignancy of the breast with a low Ki-67 index and good prognosis. Owing to the rarity of breast AdCC, the misdiagnosis rate is as high as 50%, and there is no consensus or recognized guidelines for the treatment of this disease. Therefore, it is necessary to conduct a detailed clinical and pathological analysis in combination with a literature review to improve our understanding, diagnosis, and treatment of the disease. METHODS: A 68-year-old woman sought medical attention due to a recently increasing mass in the breast. The left breast mass was 1.3 cm × 1 cm in size. We analyzed the morphology, immunohistochemistry, and molecular characteristics of the tumor removed by surgery, and reviewed relevant literature. DIAGNOSES: Solid basal AdCC of the breast. INTERVENTIONS: We performed biopsy, immunohistochemistry and molecular testing on surgical resection specimens. OUTCOMES: Combining morphological and immunohistochemical features, it is consistent with solid basal AdCC of the breast, and Fish detected MYB gene break. LESSONS: Due to the high misdiagnosis rate of AdCC, accurate histopathological diagnosis is particularly important. At present, breast conserving surgery and local tumor resection are mainly used for the treatment of breast AdCC, and postoperative adjuvant radiotherapy is feasible.


Assuntos
Neoplasias da Mama , Carcinoma Adenoide Cístico , Feminino , Humanos , Idoso , Carcinoma Adenoide Cístico/diagnóstico , Carcinoma Adenoide Cístico/cirurgia , Carcinoma Adenoide Cístico/genética , Neoplasias da Mama/diagnóstico , Neoplasias da Mama/cirurgia , Neoplasias da Mama/patologia , Imuno-Histoquímica , Mastectomia Segmentar , Biópsia
3.
Medicine (Baltimore) ; 102(43): e35783, 2023 Oct 27.
Artigo em Inglês | MEDLINE | ID: mdl-37904458

RESUMO

RATIONALE: The Hem-o-lok clip, made from a nonabsorbable polymer, and its predecessor the metal ligation clip have been used widely for laparoscopic or robot-assisted surgery to ligate the cystic duct after a cholecystectomy, to ligate the appendix after an appendectomy, or control hemorrhage or on occasion to occlude a fistula or enterotomy. Displacement of these ligation clips to distant sites is an extremely rare complication in clinical practice. PATIENT CONCERNS: The patient is a 67-year old female who sought medical attention for 3 days due to worsening intermittent upper abdominal pain and poor appetite. Gastroscopy showed both an ulcer and the presence of a foreign object embedded in the anterior wall of the duodenal bulb, consistent with what looked like a polymer-based ligation clip. After removal of the foreign body, which turned out to be a remnant of the polymer clip, no further pus was seen, but fresh granulomatous tissues were seen at the base. DIAGNOSES: a polymer-based clip-induced duodenal bulb erosion with a local contained enterically draining abscess. INTERVENTIONS: The patient recovered after removing foreign bodies under gastroscopy and receiving anti infection treatment. OUTCOMES: The patient recovered after removing foreign bodies under gastroscopy and receiving anti infection treatment. LESSONS: In laparoscopic cholecystectomy, attention should be paid to the correct surgical techniques, possibly by decreasing the number of such clips used or considering use of absorbable clips, ligature wires, ligation with absorbable suture material, or ultrasonic resection, all of which can be used for clipless cholecystectomy.


Assuntos
Colecistectomia Laparoscópica , Corpos Estranhos , Laparoscopia , Feminino , Humanos , Idoso , Polímeros , Abscesso , Duodeno , Laparoscopia/métodos , Colecistectomia Laparoscópica/métodos , Corpos Estranhos/complicações , Corpos Estranhos/cirurgia , Instrumentos Cirúrgicos
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