[The reduction of methicillin resistance in Streptococcus aureus in a hospital environment in Sousse (Tunisia)]. / Diminution de la résistance a la méticilline chez Staphylococcus aureus en milieu hospitalier à Sousse (Tunisie).

The sensitivity of Staphylococcus aureus to the principal antibiotics has been studied in a hospital environment during the period of 1989 to 1992. The resistance to methicillin was important in 1989, 1990, and 1991 (respectively 20.5; 24 and 25%). It showed an important decrease in 1992: 5%. The outstanding point over this last period is the appearance of a lower number of multi-resistant strains: M penicillin, aminoglycosides, macrolides. These strains represented 9, 10 and 11.5% in 1989, 1990 and 1991 and only 4% in 1992. This study indicates the need for increased control of the ecology and distribution of resistant strains.

[Dermatopolymyositis induced by D-penicillamine in rheumatoid polyarthritis. Apropos of 1 case with review of the literature]. / Dermatopolymyosite induite par la D-pénicillamine au cours de la polyarthrite rhumatoïde. A propos d'un cas avec revue de la littérature.

Treatment of rheumatoid arthritis (RA) with D-penicillamine (DP) is associated with development of dermatopolymyositis (DPM) in 0.2 to 1.2% of cases. A case of DPM which developed after four years DP therapy in a 58-year-old female with RA is reported. The favorable outcome after discontinuation of DP and administration of corticosteroids and the absence of recurrence or malignant disease after 4 years 9 months follow-up demonstrated the causal relationship between DP therapy and development of DPM. An analysis of 34 previously published cases of DP-induced DPM (DP/DPM) showed the following: development of DPM was not influenced by the dosage or duration of DP therapy; reported cases of DP/DPM were clinically identical with primary DPM but had a different outcome, with permanent recovery of DP/DPM occurring 1.5 to 6 months after withdrawal of DP; patients with DP/DPM had immune disorders, including antinuclear antibodies in 14 of 34 patients; the high prevalence of the B18, B35, DR4 haplotype in these patients denotes immunogenetic differences with primary DPM patients (B8-DR3) and DP-induced myasthenia (DR1).

[Conjunctival myiasis. 23 cases in the Tunisian Sahel]. / Myiases conjonctivales. A propos de 23 cas dans le Sahel tunisien.

Conjunctival lesions of ocular myiasis are common in the mediterranean region. The authors report 23 cases of conjunctival myiasis. This affection is caused by fly's larvae: Oestrus ovis presenting typically with inflamed and oedematous eyes. We diagnose the affection by directly showing the larvae on conjunctiva. The treatment consisted to extirpate larvae one by one.