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2.
Sci Rep ; 10(1): 6282, 2020 Apr 08.
Artigo em Inglês | MEDLINE | ID: mdl-32269231

RESUMO

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

3.
Oper Orthop Traumatol ; 32(1): 47-57, 2020 Feb.
Artigo em Alemão | MEDLINE | ID: mdl-30806716

RESUMO

OBJECTIVE: Elimination of pain or instability by arthrodesis of the thumb joint in functional position by dorsal plateosteosynthesis. INDICATIONS: Painful primary or secondary arthrosis of the thumb, nonreconstructable ulnar, radial or palmar instability, posttraumatic dislocation, defect injuries, bone tumors in the region of the thumb metacarpophalangeal joint. CONTRAINDICATIONS: Local infection of the thumb metacarpophalangeal joint area. SURGICAL TECHNIQUE: Dorsal approach to the thumb metacarpophalangeal (MP) joint, splitting of the extensor aponeurosis between the extensor pollicis longus and extensor pollicis brevis tendon. Opening of the anterior capsule and separation of the collateral ligaments, open up the joint, narrow concave and convex joint surface resections, adjustment of the arthrodesis position in 10-20° flexion and K­wire transfixation, dorsal plateosteosynthesis, fine adjustment of the flexion, axis and pronation position. Closure of the capsule and the periosteal gliding tissue over the plate, reconstruction of the extensor aponeurosis. POSTOPERATIVE MANAGEMENT: Splint for 3 weeks. Full load after 6-8 weeks. RESULTS: The dorsal plate arthrodesis of the thumb MP joint is a reliable surgical method with very good functional results.


Assuntos
Artrodese , Articulação Metacarpofalângica , Polegar , Artrodese/métodos , Ligamentos Colaterais , Humanos , Articulação Metacarpofalângica/cirurgia , Polegar/cirurgia , Resultado do Tratamento
4.
Hand Surg Rehabil ; 37(1): 48-55, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-29249610

RESUMO

Osteoarthritis of the first carpometacarpal joint (CMCJ1) is a common, painful condition with positive radiological findings in up to 32% of people over 50 years of age and up to 91% of people over 80 years of age. Currently, there is insufficient evidence to recommend one surgical treatment option over the others. We conducted a retrospective review of 77 patients treated for CMCJ1 osteoarthritis with plate arthrodesis between 1979 and 1996. The review included physical examination, including range of motion (ROM) of the thumb interphalangeal joint, metacarpophalangeal joint and CMCJ1, pinch grip, key grip and power grip strength, and a questionnaire on subjective outcomes (appearance, dexterity, load bearing, pain, strength, subjective overall result and if patients would choose the procedure again). The complication rate was 26%. However, the general patient satisfaction was high with 88% of patients saying they would choose to have the procedure done again. There was a significant decrease (side-to-side difference) in the ROM for palmar and radial abduction as well as opposition when compared to the opposite hand. Furthermore, there was a significant reduction (side-to-side difference) in pinch, key grip and power grip strength. ROM did not seem to have any influence on pain (and vice versa), load bearing, and the subjective overall result. No gender differences were noted. Despite the high complication rate, CMCJ1 arthrodesis remains a viable option for the treatment of CMCJ1 osteoarthritis in select patients requiring good thumb stability.


Assuntos
Artrodese/instrumentação , Placas Ósseas , Articulações Carpometacarpais/cirurgia , Osteoartrite/cirurgia , Adulto , Idoso , Feminino , Força da Mão , Humanos , Masculino , Pessoa de Meia-Idade , Satisfação do Paciente , Complicações Pós-Operatórias , Amplitude de Movimento Articular , Estudos Retrospectivos
5.
Orthopade ; 46(4): 303-314, 2017 Apr.
Artigo em Alemão | MEDLINE | ID: mdl-28361190

RESUMO

The exact knowledge of the anatomy of the fibrous skeleton of the hand is an absolute prerequisite for any treatment of Dupuytren's disease. The fibrous skeleton does not only include the palmar aponeurosis, but also numerous retinacula cutis, which are not found in current anatomy books. Here, eponyms facilitate the otherwise difficult and over-pronounced names of the fiber systems. Skoog, Legueu and Juvara, Gosset, Grapow, Grayson, Cleland, Thomine, and Barton are the most important. This systematic review of the fibers and strands is designed to help reduce iatrogenic complications.


Assuntos
Aponeurose/patologia , Contratura de Dupuytren/patologia , Fáscia/patologia , Mãos/patologia , Ligamentos/patologia , Modelos Anatômicos , Humanos
6.
J Hand Surg Eur Vol ; 41(4): 413-20, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-26228699

RESUMO

Adhesions after osteosynthesis of finger proximal phalangeal fractures often cause stiffness. To minimize adhesions, the use of an adhesion barrier has been proposed. The results until now have not been convincing. The aim of this prospective randomized trial was to evaluate the use of an adhesion barrier. The trial included any isolated, closed proximal phalangeal fracture needing plate osteosynthesis. The patients were randomized into two groups: with or without application of the adhesion barrier. The outcomes we measured were finger ranges of motion and DASH score at 6 weeks and 6 months post-operatively. A total of 42 patients (42 fingers) entered the study; 37 completed the study. The key baseline characteristics were comparable. At 6 weeks there was a trend favouring the adhesion barrier that disappeared at 6 months. Overall the results do not support the use of this device.


Assuntos
Falanges dos Dedos da Mão/cirurgia , Fixação Interna de Fraturas , Fraturas Fechadas/cirurgia , Aderências Teciduais/prevenção & controle , Placas Ósseas , Método Duplo-Cego , Feminino , Falanges dos Dedos da Mão/lesões , Humanos , Masculino , Estudos Prospectivos
7.
Handchir Mikrochir Plast Chir ; 47(4): 242-5, 2015 Aug.
Artigo em Alemão | MEDLINE | ID: mdl-26287327

RESUMO

Cryptotia is a very rare condition of ear deformity found in Europe which is more common in Asian populations. The upper ear portion is hidden and fixed in a pocket of skin of the mastoid. Conservatively, this deformity can be treated by molding of the posterior sulcus starting early after birth. Various surgical procedures are described in the literature. We successfully operated on a total of 10 ears of 9 patients with the technique described by Ichiro Ono in 1995. Here, a triangular flap is raised above the ear to reconstruct the posterior sulcus together with a rhomboid-shaped flap in the anterior part of the ear in order to elongate the helix. Among all patients, regular contours and a stable and successful outcome was observed.


Assuntos
Anormalidades Congênitas/cirurgia , Cartilagem da Orelha/anormalidades , Orelha Externa/cirurgia , Microcirurgia/métodos , Adolescente , Criança , Cartilagem da Orelha/cirurgia , Estética , Feminino , Humanos , Masculino , Cuidados Pós-Operatórios/métodos , Retalhos Cirúrgicos/cirurgia , Suíça , Cicatrização/fisiologia
8.
Rofo ; 187(3): 173-9, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25389668

RESUMO

PURPOSE: Mobile radiological image display systems are becoming increasingly common, necessitating a comparison of the features of these systems, specifically the operating system employed, connection to stationary PACS, data security and rang of image display and image analysis functions. MATERIAL AND METHODS: In the fall of 2013, a total of 17 PACS suppliers were surveyed regarding the technical features of 18 mobile radiological image display systems using a standardized questionnaire. The study also examined to what extent the technical specifications of the mobile image display systems satisfy the provisions of the Germany Medical Devices Act as well as the provisions of the German X-ray ordinance (RöV). RESULTS: There are clear differences in terms of how the mobile systems connected to the stationary PACS. Web-based solutions allow the mobile image display systems to function independently of their operating systems. The examined systems differed very little in terms of image display and image analysis functions. CONCLUSION: Mobile image display systems complement stationary PACS and can be used to view images. The impacts of the new quality assurance guidelines (QS-RL) as well as the upcoming new standard DIN 6868 - 157 on the acceptance testing of mobile image display units for the purpose of image evaluation are discussed.


Assuntos
Computadores de Mão , Sistemas de Informação em Radiologia/instrumentação , Telerradiologia/instrumentação , Segurança Computacional/legislação & jurisprudência , Computadores de Mão/legislação & jurisprudência , Apresentação de Dados , Desenho de Equipamento , Alemanha , Humanos , Garantia da Qualidade dos Cuidados de Saúde/legislação & jurisprudência , Sistemas de Informação em Radiologia/legislação & jurisprudência , Design de Software , Telerradiologia/legislação & jurisprudência
9.
Handchir Mikrochir Plast Chir ; 46(1): 12-7, 2014 Feb.
Artigo em Alemão | MEDLINE | ID: mdl-24573825

RESUMO

BACKGROUND: Surgical treatment of osteoporotic distal radius fractures with locking plates does not completely prevent loss of reduction. Additional bone deficit stabilisation with the use of bone substitute materials is receiving increased attention. Most knowledge on the in vivo behavior of bone substitutes originates from a small number of animal models after its implantation in young, good vascularized bone. PURPOSE: This paper investigates the osteoconductivity, resorption and biocompatibility of beta-tricalcium phosphate as a temporary bone replacement in osteoporotic type distal radius fractures. PATIENTS AND METHODS: 15 bone samples taken from the augmented area of the distal radius of elderly people during metal removal were examined. RESULTS: The material was found to be osteoconductive, good degradable, and biocompatible. Degrading process and remodelling to woven bone seem to require more time than in available comparative bioassays. CONCLUSIONS: The material is suitable for temporary replacement of lost, distal radius bone from the histological point of view.


Assuntos
Regeneração Óssea/fisiologia , Substitutos Ósseos , Fosfatos de Cálcio/uso terapêutico , Fixação Interna de Fraturas/métodos , Fraturas por Osteoporose/cirurgia , Fraturas do Rádio/cirurgia , Traumatismos do Punho/cirurgia , Idoso , Idoso de 80 Anos ou mais , Remodelação Óssea/fisiologia , Feminino , Seguimentos , Consolidação da Fratura/fisiologia , Humanos , Masculino , Teste de Materiais , Pessoa de Meia-Idade , Osseointegração/fisiologia , Fraturas por Osteoporose/patologia , Rádio (Anatomia)/patologia , Rádio (Anatomia)/cirurgia , Fraturas do Rádio/patologia , Suíça , Traumatismos do Punho/patologia
13.
Handchir Mikrochir Plast Chir ; 43(5): 298-301, 2011 Oct.
Artigo em Alemão | MEDLINE | ID: mdl-21935849

RESUMO

This study examines retrospectively the impact of operative and perioperative factors on the recurrence rate of finger and wrist cysts.Out of a total of 237 recorded cyst operations in 201 patients, 46% were carried out for dorsal wrist ganglia, 38% for finger ganglia, and 16% for palmar wrist cysts. 133 (56%) patients answered on a mailed questionnaire. At an average of 2 years 79 of these 133 patients could be re-examined. Data concerning history, size of the cyst, location of the cyst, the hand surgical experience of the performing surgeon were taken from the charts. Statistical analysis were performed.There were 48 (36.1%; n=133) recurrences. Most (79.2%) occurred within the first year. A higher recurrence rate was observed in patients with a longer history, larger ganglia, and when patients were operated by less experienced surgeons. Recurrence rates did neither correlate with the ganglion location, the patient's age, and gender.


Assuntos
Mãos/cirurgia , Complicações Pós-Operatórias/etiologia , Cisto Sinovial/cirurgia , Punho/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Recidiva , Estudos Retrospectivos , Fatores de Risco , Adulto Jovem
14.
J Hand Surg Eur Vol ; 36(9): 778-86, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-21750097

RESUMO

Axillary block for brachial plexus anaesthesia is a popular anaesthetic technique for hand surgery with different approaches. We investigated the efficacy of the blind and ultrasound-guided approaches administered by a hand surgeon. A total of 141 patients were prospectively randomized to Group A without and Group B with ultrasound guidance. The principal variables evaluated were number of failures, duration of surgery, time to onset of anaesthesia, volume of anaesthetic injected, and complications. The success rate and the mean time to onset of anaesthesia were significantly better under ultrasound guidance. The duration of surgery and the rate of complications did not differ. Ultrasound-guided plexus anaesthesia is markedly more effective than the blind technique when performed by a hand surgeon.


Assuntos
Plexo Braquial/diagnóstico por imagem , Bloqueio Nervoso/métodos , Ultrassonografia de Intervenção , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Anestésicos Locais/administração & dosagem , Axila , Bupivacaína/administração & dosagem , Epinefrina/administração & dosagem , Feminino , Humanos , Masculino , Mepivacaína/administração & dosagem , Pessoa de Meia-Idade , Estudos Prospectivos , Simpatomiméticos/administração & dosagem , Fatores de Tempo , Adulto Jovem
15.
Handchir Mikrochir Plast Chir ; 43(2): 76-80, 2011 Apr.
Artigo em Alemão | MEDLINE | ID: mdl-21509698

RESUMO

BACKGROUND: Propeller flaps represent an elegant and reliable method for soft-tissue reconstruction of the extremities and trunk, obviating the need for free tissue transfer. Preoperative localisation of perforators adjacent to the defect is important regarding the pivot point and length of the flap. Most commonly unidirectional Doppler sonography is used. The reliability of this method regarding propellerflaps has not thoroughly been evaluated. The aim of this study is to assess the positive predictive value of this method for planning propeller flaps. PATIENTS AND METHOD: In a total of 68 patients, soft-tissue reconstruction using propeller flaps was planned with unidirectional Doppler sonography. Defects were located on the lower extremity in 48 cases, the buttock area in 15 cases and the trunk in 5 cases. RESULTS: In 12 cases no adequate perforators were located intraoperatively despite a positive Doppler signal. In the lower extremity Doppler produced a false-positive result in 21% of the cases, whereas in the buttock region only 13% false positives result were found. The positive predictive value overall was 82%. When no perforator was located, flap coverage was achieved using the reverse sural artery flap in 6 cases, the free peroneal artery perforator flap in 3 cases, local advancement flaps in 2 cases and skin grafting in 1 case. DISCUSSION: The reliability of unidirectional Doppler sonography is inadequate for localisation and selection of the dominant perforator when planning propeller flaps. A high rate of false-positive results needs to be anticipated especially distally in the extremities. In 18% of cases an alternative surgical plan was required to achieve soft tissue coverage. We recommend using colour duplex sonography for a more reliable preoperative localisation of perforators.


Assuntos
Microcirurgia/métodos , Retalhos Cirúrgicos/irrigação sanguínea , Coleta de Tecidos e Órgãos/métodos , Ultrassonografia Doppler , Humanos , Microvasos/diagnóstico por imagem , Necrose , Tratamento de Ferimentos com Pressão Negativa , Complicações Pós-Operatórias/patologia , Cuidados Pré-Operatórios , Estudos Retrospectivos , Sensibilidade e Especificidade , Retalhos Cirúrgicos/patologia , Cicatrização/fisiologia
16.
Sci Rep ; 1: 57, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-22355576

RESUMO

A growing number of X-ray sources based on the free-electron laser (XFEL) principle are presently under construction or have recently started operation. The intense, ultrashort pulses of these sources will enable new insights in many different fields of science. A key problem is to provide x-ray optical elements capable of collecting the largest possible fraction of the radiation and to focus into the smallest possible focus. As a key step towards this goal, we demonstrate here the first nanofocusing of hard XFEL pulses. We developed diamond based Fresnel zone plates capable of withstanding the full beam of the world's most powerful x-ray laser. Using an imprint technique, we measured the focal spot size, which was limited to 320 nm FWHM by the spectral band width of the source. A peak power density in the focal spot of 4×10(17)W/cm(2) was obtained at 70 fs pulse length.

17.
Actas Urol Esp ; 34(3): 278-81, 2010 Mar.
Artigo em Espanhol | MEDLINE | ID: mdl-20416246

RESUMO

OBJECTIVES: To assess the relationship between mechanical preparation of the bowel before endourological surgery and the occurrence of postoperative complications. MATERIALS AND METHODS: A prospective, randomized study was conducted in 162 patients undergoing TUR of the bladder, TURP, and lase adenomectomy from October 2008 to February 2009. No patient was excluded. An enema was administered before surgery to 66 patients, but not to the remaining patients. Variables analyzed included occurrence of urinary tract infection (UTI), fever, acute urinary retention (AUR), postoperative need for enemas or laxatives, surgical field contamination, and mean hospital stay. A descriptive analysis, a means comparison (t test), and a Chi-square test were performed. RESULTS: Mean patient age was 70.5 years (SD+/-10.62), and mean hospital stay 4.8 days (SD+/-3.9). UTI occurred in 6.2% of patients, fever in 3.1%, and AUR in 1.2%, and 15.4% of patients required enemas or laxatives. Fecal contamination of the surgical field was found in one patient (0.6%). There were no statistically significant differences between the study groups in the variables analyzed. CONCLUSIONS: In our series, bowel preparation using enema has shown no value for decreasing postoperative complications of endourological surgery.


Assuntos
Endoscopia/efeitos adversos , Enema , Cuidados Pré-Operatórios/métodos , Idoso , Humanos , Complicações Pós-Operatórias/prevenção & controle , Estudos Prospectivos
18.
Handchir Mikrochir Plast Chir ; 42(1): 49-54, 2010 Feb.
Artigo em Alemão | MEDLINE | ID: mdl-20205067

RESUMO

Self-mutilation in the context of factitious disorder can lead to prolonged and complicated treatment in every medical field. Because of a prevalence of 1-5% in hospitalised patients, it is important to be aware of this disorder to protect patients from self- and foreign-induced harm. Often the patient history gives important hints. The different manifestations of this disorder, the specific doctor-patient relationship, several techniques of confrontation and current treatment are presented. Clinical cases from the fields of hand and plastic surgery are presented.


Assuntos
Transtornos Autoinduzidos/diagnóstico , Traumatismos da Mão/cirurgia , Mãos/cirurgia , Síndrome de Munchausen/diagnóstico , Síndrome de Munchausen/cirurgia , Procedimentos de Cirurgia Plástica , Complicações Pós-Operatórias/diagnóstico , Distrofia Simpática Reflexa/diagnóstico , Distrofia Simpática Reflexa/cirurgia , Automutilação/diagnóstico , Automutilação/cirurgia , Adulto , Diagnóstico Diferencial , Transtornos Autoinduzidos/prevenção & controle , Transtornos Autoinduzidos/psicologia , Feminino , Traumatismos da Mão/psicologia , Humanos , Síndrome de Munchausen/prevenção & controle , Síndrome de Munchausen/psicologia , Síndrome de Munchausen Causada por Terceiro , Equipe de Assistência ao Paciente , Relações Médico-Paciente , Complicações Pós-Operatórias/prevenção & controle , Complicações Pós-Operatórias/psicologia , Distrofia Simpática Reflexa/psicologia , Automutilação/prevenção & controle , Automutilação/psicologia , Adulto Jovem
19.
Actas urol. esp ; 34(3): 278-281, mar. 2010. tab
Artigo em Espanhol | IBECS | ID: ibc-81701

RESUMO

Objetivos: Determinar la relación entre la preparación mecánica intestinal previa a la cirugía endourológica y la existencia de complicaciones postoperatorias. Material y métodos: Diseñamos un estudio prospectivo y aleatorizado con 162 pacientes intervenidos mediante RTU vesical, RTU prostática y adenomectomía láser entre octubre de 2008 y febrero de 2009, sin excluir a ningún paciente. A 66 pacientes se les administró un enema previo a la cirugía y a los restantes no. Analizamos la incidencia de infección urinaria (ITU), fiebre, retención aguda de orina, necesidad de enemas o laxantes durante el postoperatorio, contaminación del campo quirúrgico y la estancia media. Realizamos un análisis descriptivo, comparación de medias (t test) y chi cuadrado. Resultados: La edad media fue de 70,5 años (DS±10,62) y la estancia media fue de 4,8 días (DS±3,9). Un 6,2% de los pacientes tuvo ITU, un 3,1% tuvo fiebre, un 1,2% presentó retención aguda de orina y el 15,4% necesitó enemas o laxantes. Se recogió un caso de contaminación con heces del campo quirúrgico (0,6%). No se encontraron diferencias estadísticamente significativas para las variables analizadas entre ambos grupos de estudio. Conclusiones: En nuestra serie, la preparación intestinal mediante el empleo de enemas no ha demostrado utilidad para disminuir complicaciones durante el postoperatorio de cirugía endourológica (AU)


Objectives: To assess the relationship between mechanical preparation of the bowel before endourological surgery and the occurrence of postoperative complications. Materials and methods: A prospective, randomized study was conducted in 162 patients undergoing TUR of the bladder, TURP, and lase adenomectomy from October 2008 to February 2009. No patient was excluded. An enema was administered before surgery to 66 patients, but not to the remaining patients. Variables analyzed included occurrence of urinary tract infection (UTI), fever, acute urinary retention (AUR), postoperative need for enemas or laxatives, surgical field contamination, and mean hospital stay. A descriptive analysis, a means comparison (t test), and a Chi-square test were performed. Results: Mean patient age was 70.5 years (SD+/−10.62), and mean hospital stay 4.8 days (SD+/−3.9). UTI occurred in 6.2% of patients, fever in 3.1%, and AUR in 1.2%, and 15.4% of patients required enemas or laxatives. Fecal contamination of the surgical field was found in one patient (0.6%). There were no statistically significant differences between the study groups in the variables analyzed. Conclusions: In our series, bowel preparation using enema has shown no value for decreasing postoperative complications of endourological surgery (AU)


Assuntos
Humanos , Endoscopia/métodos , Cuidados Pré-Operatórios/métodos , Doenças Urológicas/cirurgia , Estudos Prospectivos , Ressecção Transuretral da Próstata/métodos , Enema
20.
Zentralbl Chir ; 134(5): 468-73, 2009 Sep.
Artigo em Alemão | MEDLINE | ID: mdl-19757348

RESUMO

BACKGROUND: Merkel cell carcinoma is a rare, -aggressive, neuroendocrine malignancy of the skin. Over the period from June 2005 to January 2007 (18 months) 7 Merkel cell carcinomas in different tumour stages and localisations were treated in our department for hand, plastic and reconstructive surgery. Given an incidence rate of approximately 0.1-0.4 per 100 000 inhabitants, this accumulation of cases is considerably higher than would be statistically expected. This led us to analyse our cases retrospectively and provided the opportunity to discuss the treatment modalities on the basis of the current literature. PATIENTS AND METHODS: All patients were referred to our clinic after incomplete tumour excision and histopathological diagnosis elsewhere, for further surgical treatment. Two female and 5 male patients, aged 63 to 83 years, were treated. The patients' data were collected and analysed retrospectively. RESULTS: In all cases an R0 resection could be achieved, with safety resection margins between 1.5 cm and 4.5 cm. The reconstruction of the resulting defects was achieved by skin transplants in six cases and a primary suture in one case. All patients received adjuvant radiotherapy. Furthermore, three patients received adjuvant chemotherapy due to metastases of the progressed Merkel cell carcinoma. Three patients remained free of recurrence and in two patients a progression of the tumour disease could be impeded, whilst two patients succumbed to their disease. CONCLUSIONS: In the case of an early diagnosis, an R0 resection can usually be achieved. A safety resection margin of a minimum of 1.5 cm in the face and 3 cm for localisation on the extremities should be obtained. To reduce the local recurrence rate, adjuvant radiotherapy should be conducted. The benefit from chemotherapy still remains unclear.


Assuntos
Carcinoma de Célula de Merkel/radioterapia , Carcinoma de Célula de Merkel/cirurgia , Neoplasias Oculares/radioterapia , Neoplasias Oculares/cirurgia , Equipe de Assistência ao Paciente , Neoplasias Cutâneas/radioterapia , Neoplasias Cutâneas/cirurgia , Idoso , Idoso de 80 Anos ou mais , Biópsia , Carcinoma de Célula de Merkel/tratamento farmacológico , Carcinoma de Célula de Merkel/patologia , Quimioterapia Adjuvante , Terapia Combinada , Progressão da Doença , Neoplasias Oculares/tratamento farmacológico , Neoplasias Oculares/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Metástase Neoplásica , Estadiamento de Neoplasias , Cuidados Paliativos , Radioterapia Adjuvante , Procedimentos de Cirurgia Plástica , Estudos Retrospectivos , Pele/patologia , Neoplasias Cutâneas/tratamento farmacológico , Neoplasias Cutâneas/patologia , Retalhos Cirúrgicos , Análise de Sobrevida
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