[The proteinase and alpha 1-antitrypsin activities in the tissues during emotional stress in rabbits]. / Aktivnost' proteinaz i al'fa 1-antitripsina v tkaniakh pri émotsional'nom stresse u krolikov.

The experiments on rabbits under acute emotional stress have revealed a rise in activity of proteinases of blood serum, salivary glands and no changes of this activity in watery moisture of an eye. The activity of alpha-antitrypsin in watery moisture of an eye, unlike the blood serum, significantly increased, that evidently prevented the activation of proteolysis in it. The emotional stress is also accompanied by the intensification of fibrinolysis, one of the most important proteolytic systems of the blood.

[Role of the mucous barrier in the pathogenesis of stress ulcers of the stomach]. / Rol' slizistogo bar'era v patogeneze stressornykh iazv zheludka.

Using the model of immobilizing stress in rats, it has been established that the content of sialic acids in the stomach mucous membrane (SMM) and blood serum rises with simultaneous activation of proteolytic enzymes in them. The preliminary adaptation to short stressor influences parallel with an antipathogenic effect normalizes the content of sialic acids in the blood serum and SMM. The conclusion is made on the essential role of the degradation of gastric mucus in pathogenesis of stress ulcers.

[The adrenergic mechanisms of the inhibition of the gastric acid-forming function in acute stress]. / Adrenergicheskie mekhanizmy tormozheniia kislotoobrazuiushchei funktsii zheludka pri ostrom stresse.

It was demonstrated in experiments on Wistar rats that blockade of central adrenergic structures by thymopentin and beta-adrenergic receptors by inderal prevents stress inhibition of hydrochloric acid secretion. Normalization of the antioxidative protection of the stomach which prevents activation of the processes of free-radical oxidation in it plays an essential role in the mechanism of the stress-protective effect of adrenergic influences blockade on the gastric acid-producing function.

[Reaction of the salivary glands to acute stress]. / Reaktsiia sliunnykh zhelez na ostryi stress.

Experiment on male rats has shown that acute stress suppressed amylase and superoxide dismutase activity in the submandibular salivary glands. The influence of short repeated stresses weakened the inhibiting effect of the acute stress on the activity of enzymes. A conclusion is drawn about the high sensibility of salivary glands to stress influences.

[Characteristic of gastric response to acute and chronic stress and to their combination]. / Osobennosti reaktsii zheludka na ostryi i khronicheskii stressy, a takzhe na ikh sochetanie.

Experiments on 39 rats subjected to the effect of acute, chronic stresses and to that of their combination have revealed a parallelism between the degree of the ulcerogenic effect and depression of antioxidant activity of the stomach tissue cells.

[Effect of fluorine on enzyme activity in the small intestine mucosa during absorption of sodium, potassium, monosaccharides and amino acids]. / Fliianie ftora na aktivnost' fermentov slizistoi tonkoi kishki pri vsasyvanii natriia, kaliia, monosakharov i aminokislot.

Effect of NaF on ATP-ase, creatine kinase, acid and basic phosphatases activity of small intestine mucosa in white rats during enteral administration of NaCl, KCl solutions has been studied under conditions of acute experiment. Inhibition of the Mg2+-ATP-ase activity by 13%, general ATP-ase activity by 25%, creatine kinase by 22% and a 2.2-3 fold inhibition of Na, K+-ATP-ase activity is observed. Acid and basic phosphatase activity does not change, swelling of mucosa is observed. The acid phosphatase activity in the intestinal contents increases 1.5 times, basic phosphatase activity--1.7 times, creatine amount--1.7 times, Pi amount 1.8 times. In experiments in vitro F- produces 20% activation of the basic phosphatase of mucosa and a 2.6-fold inhibition of the acid phosphatase. Rate of fructose absorption falls by 34%, that of methionine--by 29%, glucose--by 24%, glutaminic acid--by 10%. Activity of general ATP-ase in this case decreases by 22, 15, 27, 20% respectively. It is supposed that the F- effect results in destabilization of the membrane structures of the intestine mucosa.