Measuring the Impact of Whole-Body Computed Tomography on Hospital Length of Stay in Blunt Trauma.

RATIONALE AND OBJECTIVES: Whole-body computed tomography (WBCT) imaging has become commonplace in some emergency departments (EDs) for trauma where management is dependent on rapid diagnosis achieved through comprehensive imaging. The purpose of this study was to assess the value that computed tomography (CT) imaging contributes to trauma patients by retrospectively comparing hospital length of stay (LOS) between WBCT and selective CT imaging, while controlling for hemodynamic stability and socio-economic considerations. MATERIALS AND METHODS: This study was institutional review board approved. The institutional trauma registry database was cross-referenced with our radiology information system database to identify adult patients who sustained blunt trauma between July 2011 and June 2013 and received CT imaging. Propensity score weighting was utilized to achieve balance in baseline covariates, including demographics, hemodynamic stability, Glasgow Coma Scale, and socioeconomic factors. A generalized linear model was used to compare LOS between imaging types, and a multinomial logistic regression was utilized to analyze differences in discharge disposition. RESULTS: A total of 2291 patients were identified of which 14.5% underwent WBCT imaging. WBCT patients had an insignificantly longer inpatient hospital LOS of 0.31 days (P = 0.54), and insignificantly higher odds of being discharged to a nursing home facility (versus home, odds ratio = 1.29 [P = 0.34]) when compared to those who received selective CT. CONCLUSION: WBCT imaging did not have a statistically significant effect on inpatient hospital LOS or discharge disposition.

Effect of Naproxen Prophylaxis on Heterotopic Ossification Following Hip Arthroscopy: A Double-Blind Randomized Placebo-Controlled Trial.

BACKGROUND: Heterotopic ossification (HO) is a known complication of hip arthroscopy. Our objective was to determine the effect of postoperative naproxen therapy on the development of HO following arthroscopic surgery for femoroacetabular impingement. METHODS: Between August 2011 and April 2013, 108 eligible patients were enrolled and randomized to take naproxen or a placebo for three weeks postoperatively. Radiographs were made at routine follow-up visits for one year following surgery. The primary outcome measure was the development of HO, as classified with the Brooker criteria and two-dimensional measurements on radiographs made at least seventy-five days postoperatively (average, 322 days). The primary analysis, performed with a Fisher exact test, compared the proportion of subjects with HO between the treatment and control groups. A single a priori interim analysis was planned at the midpoint of the study. RESULTS: Our data safety and monitoring board stopped this study when the interim analysis showed that the stopping criterion had been met for demonstration of efficacy of the naproxen intervention. The prevalence of HO was 46% (twenty-two of the forty-eight in the final analysis) in the placebo group versus 4% (two of forty-eight) in the naproxen group (p < 0.001). Medication compliance was 69% overall, but it did not differ between the naproxen and placebo groups. Minor adverse reactions to the study medications were reported in 42% of the patients taking naproxen versus 35% of those taking the placebo (p = 0.45). CONCLUSIONS: In this trial, prophylaxis with naproxen was effective in reducing the prevalence of HO without medication-related morbidity.