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1.
Surg Obes Relat Dis ; 17(4): 701-710, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-33551252

RESUMO

BACKGROUND: Cannabis is second only to alcohol as a substance of abuse and dependence in the United States. While there is extensive research examining alcohol use and bariatric surgery, there is currently little research and there are no published guidelines specific to cannabis use and bariatric surgery. OBJECTIVES: To identify major themes and general guidelines applied by bariatric surgery psychology clinicians. SETTING: This practice survey was disseminated to bariatric surgery psychologists at various U.S. academic medical centers, hospitals, and private practices. METHODS: An electronic, 35-question survey was sent to 47 bariatric surgery psychologists to collect information on current clinical practice guidelines regarding cannabis use before and after bariatric surgery. RESULTS: The survey questionnaire was completed by 34 (72.34%) bariatric surgery psychologists. The major identified themes included: (1) the lack of a standardized assessment of cannabis use; (2) a requirement for 3 months of abstinence from cannabis before bariatric surgery; (3) recommended lifetime abstinence from cannabis after bariatric surgery; and (4) discussion of cannabis use risks following bariatric surgery, including appetite stimulation, addiction potential, and possible negative impacts on judgment. CONCLUSION: Cannabis use will likely further increase in the United States. This survey highlighted common bariatric surgery psychology practices in the absence of extensive research and published guidelines. These findings suggest a preliminary framework with which to address cannabis use in patients seeking bariatric surgery. It is recommended that professional organizations and societies build on these initial survey findings to develop guidelines for more consistent, evidence-based practice regarding cannabis use and bariatric surgery.


Assuntos
Cirurgia Bariátrica , Cannabis , Consumo de Bebidas Alcoólicas , Humanos , Prática Psicológica , Inquéritos e Questionários , Estados Unidos
2.
Mayo Clin Proc ; 95(3): 527-540, 2020 03.
Artigo em Inglês | MEDLINE | ID: mdl-32138881

RESUMO

The prevalence of class 3 obesity (body mass index ≥40 kg/m2) is 7.7% of the United States adult population; thus, more than 25 million people may be medically appropriate for consideration of bariatric surgery as therapy for severe obesity. Although bariatric surgery is the most effective therapy for patients with severe obesity, the surgery is performed in less than 1% of patients annually for whom it may be appropriate. Patients' and medical professionals' misperceptions about obesity and bariatric surgery create barriers to accessing bariatric surgery that are not given adequate attention and clinical consideration. Commonly cited patient barriers are lack of knowledge about the severity of obesity, the perception that obesity is a lifestyle problem rather than a chronic disease, and fear that bariatric surgery is dangerous. Medical professional barriers include failing to recognize causes of obesity and weight gain, providing recommendations that are inconsistent with current obesity treatment guidelines, and being uncomfortable counseling patients about treatment options for severe obesity. Previous research has revealed that medical professional counseling and accurate perception of the health risks associated with severe obesity are strong predictors of patients' willingness to consider bariatric surgery. This article reviews patient and medical professional barriers to acceptance of bariatric surgery as a treatment of medical necessity and offers practical advice for medical professionals to rethink perspectives about bariatric surgery when it is medically and psychologically appropriate.


Assuntos
Cirurgia Bariátrica/normas , Obesidade Mórbida/cirurgia , Seleção de Pacientes , Atitude do Pessoal de Saúde , Tomada de Decisões , Humanos , Obesidade Mórbida/epidemiologia , Obesidade Mórbida/psicologia , Estados Unidos/epidemiologia
3.
Eat Behav ; 34: 101310, 2019 08.
Artigo em Inglês | MEDLINE | ID: mdl-31374335

RESUMO

This study developed and provided initial validation for the Support for Healthy Lifestyle (SHeL), a set of scales designed to measure adolescent-perceived social support of healthy eating and physical activity. Item pool development utilized a prior focus group study of adolescents' perceptions of socially supportive behavior and a review of the literature on social support for health behavior change in adolescents. Exploratory factor analysis of the item pool completed by 220 adolescents, internal consistency estimates, and expert review of items and consensus resulted in 9 scales for the SHeL: Family Healthy Eating Support, Family Physical Activity Support, Family Hypocritical Control, Peer Health Eating Support, Peer Physical Activity Support, Peer Undermining, Professional Healthy Eating Support, Professional Physical Activity Support, and Professional General Support. Scale internal reliability estimates were α = 0.73-0.96. Supporting construct validity, the SHeL showed a pattern of stronger correlations between measures of the same source (parent/peer) and target behavior (healthy eating/physical activity) and stronger correlations with corresponding Sallis scales vis-à-vis other Sallis scales, with exceptions related to peer support for healthy eating. Divergent validity was somewhat limited, including in two instances, the SHeL scale was more strongly correlated with another SHeL scale. Supporting criterion validity, often the SHeL scales were correlated with related health behaviors. This study provided important psychometric information for a new measurement of social support for health behavior for adolescents. Further research with larger, more diverse, and treatment-seeking populations is needed to provide further validation of the SHeL and to begin to establish normative scores.


Assuntos
Dieta Saudável/psicologia , Exercício Físico/psicologia , Comportamento Alimentar/psicologia , Comportamentos Relacionados com a Saúde , Psicometria/métodos , Apoio Social , Adolescente , Análise Fatorial , Feminino , Grupos Focais , Humanos , Masculino , Grupo Associado , Reprodutibilidade dos Testes , Comportamento Social , Inquéritos e Questionários
4.
Surg Endosc ; 32(1): 252-259, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-28664438

RESUMO

BACKGROUND AND AIMS: Many patients who undergo bariatric surgery will experience weight regain and effective strategies are needed to help these patients. A dilated gastrojejunal anastomosis (GJA) has been associated with weight recidivism after Roux-en-Y gastric bypass surgery (RYGB). Endoscopic transoral outlet reduction (TORe) with a full thickness endoscopic suturing device (Overstitch, Apollo Endosurgery, Austin, TX) is a minimally invasive therapeutic option. The primary aim of this project was to examine the safety and long-term efficacy data from three bariatric surgery centers and to conduct a systematic review and meta-analysis of the existing literature. METHODS: Patients who underwent TORe with the Overstitch device from Jan 2013 to Nov 2016 at 3 participating bariatric surgery centers were included in the multicenter analysis. For the systematic review and meta-analysis, a comprehensive search of multiple English databases was conducted. Random effects model was used. RESULTS: 130 consecutive patients across three centers underwent TORe with an endolumenal suturing device. These patients (mean age 47; mean BMI 36.8) had experienced 24.6% weight regain from nadir weight after RYGB. Average weight lost at 6, 12, and 18 months after TORe was 9.31 ± 6.7 kg (N = 84), 7.75 ± 8.4  kg (N = 70), 8 ± 8.8 kg (N = 46) (p < 0.01 for all three time points), respectively. The meta-analysis included 330 patients. The pooled weight lost at 12 months was 8.4 kg (95% CI 6.5-10.3) with no significant heterogeneity across included studies (p = 0.07). Overall, 14% of patients experienced nausea, 18% had pain and 8% required a repeat EGD. No serious adverse events reported. CONCLUSION: When implemented as part of a multidisciplinary intervention, TORe using endolumenal suturing is safe, reproducible, and effective approach to manage weight recidivism after RYGB and should be utilized early in the management algorithm of these patients.


Assuntos
Endoscopia/métodos , Derivação Gástrica , Obesidade Mórbida/cirurgia , Reoperação/métodos , Técnicas de Sutura , Aumento de Peso , Adulto , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Recidiva , Estudos Retrospectivos , Resultado do Tratamento
5.
Eat Weight Disord ; 23(1): 87-94, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-27473870

RESUMO

PURPOSE: To elicit patient experiences of weight management discussions with providers and provide recommendations for future weight-related discussions. METHODS: 1000 patients who recently saw their provider for non-weight specific appointments were mailed measures of demographics, self-reported height and weight, activity level, adherence, perceptions of and recommendations for weight-related discussions, and internalized weight bias. This study was primarily descriptive and utilized a mixed method design including collection of quantitative and qualitative data. RESULTS: 242 patients responded (24 % response rate); 32.4 % overweight (N = 72), 41.9 % obese (N = 93). 47 % of overweight and 71 % of obese patients recalled that their provider discussed weight; 92 % were motivated to follow recommendations and 89 % felt confident doing so. Most patients (75 %) would like their provider to be "very direct/straightforward" when discussing weight, and 52 % would be "not at all offended" if they were diagnosed as "overweight/obese." Most patients (63 %) reported being "extremely comfortable" discussing weight with providers. Patients with higher BMI had higher levels of internalized weight bias (p < .001) and wanted their provider to "discuss weight sensitively" (p < .05). CONCLUSION: This study suggests that patients have important preferences that providers should be mindful of when discussing weight. While these discussions can be challenging, most patients report that they would be comfortable having these conversations directly and most would have enhanced motivation and confidence following these conversations. Communicating about weight is needed and desired by patients; doing so sensitively with those at higher weight is essential.


Assuntos
Peso Corporal/fisiologia , Motivação , Obesidade/terapia , Sobrepeso/terapia , Preferência do Paciente , Relações Médico-Paciente , Idoso , Idoso de 80 Anos ou mais , Comunicação , Feminino , Pessoal de Saúde , Humanos , Masculino , Pessoa de Meia-Idade
6.
Obes Surg ; 27(10): 2759-2767, 2017 10.
Artigo em Inglês | MEDLINE | ID: mdl-28815388

RESUMO

BACKGROUND: Helping patients determine which type of bariatric surgery, Roux-en-Y gastric bypass (RYGB) or vertical sleeve gastrectomy (VSG), may be the best treatment can be challenging. This study investigated psychological correlates and their influence on weight loss for patients who underwent RYGB or VSG. METHODS: Four hundred twenty-two patients (RYGB = 305; VSG = 117) completed screening questionnaires presurgery and underwent surgery between August 2012 and April 2015. Associations between demographics and questionnaires with percentage weight change were evaluated using multivariable linear regression models. RESULTS: Median age was 48 years and median BMI 45.3 kg/m2 presurgery. Median percentage changes in weight from baseline to years 1 and 2 follow-up were - 31.5% (range - 52.2 to - 9.2%) and - 31.2% (range - 50.0 to - 1.2%) for RYGB and 25.3% (range - 49.8 to - 4.7%) and - 23.3% (range - 58.9 to - 1.6%) for VSG, respectively. Linear regression models revealed that younger patients lost more weight than older patients at years 1 (RYGB p < 0.0001; VSG p = 0.0001) and 2 (RYGB p = 0.005; VSG p = 0.002). No psychological correlates were significantly associated with weight loss outcomes. Post hoc analyses comparing patients who had surgery to those in the same cohort who did not have surgery revealed significantly higher rates of depression (p < 0.001), anxiety (p < 0.001), binge eating (p = 0.003), night eating (p < 0.001), food addiction (p = 0.042), and lower self-efficacy (p < 0.001) among patients who did not have surgery. DISCUSSION: Patients who are psychologically higher functioning are more likely to complete the evaluation process and undergo bariatric surgery. For patients who had surgery, psychological correlates were not associated with weight loss outcome for either RYGB or VSG. Implications for surgical choice are discussed.


Assuntos
Cirurgia Bariátrica/métodos , Comportamento de Escolha , Tomada de Decisões , Obesidade Mórbida/psicologia , Obesidade Mórbida/cirurgia , Adulto , Afeto/fisiologia , Cirurgia Bariátrica/efeitos adversos , Cirurgia Bariátrica/psicologia , Estudos de Coortes , Ingestão de Alimentos/psicologia , Feminino , Gastrectomia/métodos , Gastrectomia/psicologia , Derivação Gástrica/métodos , Derivação Gástrica/psicologia , Comportamentos Relacionados com a Saúde/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade , Redução de Peso/fisiologia
7.
Pharmacotherapy ; 37(11): 1374-1382, 2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-28845898

RESUMO

STUDY OBJECTIVE: The extended-release (ER) form of venlafaxine is preferred because of improved patient adherence, but the immediate-release (IR) form is frequently used after Roux-en-Y gastric bypass (RYGB) surgery because of concerns for malabsorption. The objective of this study was to determine whether a statistically significant and predictable change in the bioavailability of venlafaxine ER capsules occurs after RYGB. DESIGN: Prospective nonblinded single-dose pharmacokinetic study. SETTING: Clinical research unit at a large tertiary care medical practice. PATIENTS: Ten adult pre-bariatric surgery patients who met the criteria for noncomplicated RYGB were enrolled and served as their own controls. INTERVENTIONS: Patients were administered one venlafaxine ER 75-mg capsule at two visits-the first visit at least 1 week before undergoing RYGB and the second visit 3-4 months after RYGB. Blood samples were collected at predetermined intervals over 48 hours after each dose, and the pharmacokinetics of venlafaxine were measured. MEASUREMENTS AND MAIN RESULTS: Plasma levels of venlafaxine and its primary metabolite, O-desmethylvenlafaxine (ODV), were compared at baseline and 3-4 months after RYGB. The areas under the serum concentration-time curves from 0-24 hours (AUC0-24 ) for venlafaxine (mean ± SD 734 ± 602 vs 630 ± 553 ng·hr/ml, p=0.22) and ODV (mean ± SD 894 ± 899 vs 1083 ± 972 ng·hr/ml, p=0.07) were similar before and after RYGB. Using a bioequivalence approach, differences in pre-RYGB and post-RYGB values of AUC0-24 , peak serum concentration, and time to peak serum concentration were not statistically significant for either venlafaxine or ODV. CONCLUSION: This study suggests that RYGB does not significantly alter the amount of venlafaxine or its active metabolite, ODV, absorbed from a venlafaxine ER capsule or the time over which it is absorbed.


Assuntos
Derivação Gástrica/métodos , Obesidade/cirurgia , Inibidores da Recaptação de Serotonina e Norepinefrina/administração & dosagem , Cloridrato de Venlafaxina/administração & dosagem , Adulto , Idoso , Área Sob a Curva , Disponibilidade Biológica , Cápsulas , Preparações de Ação Retardada , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Inibidores da Recaptação de Serotonina e Norepinefrina/farmacocinética , Equivalência Terapêutica , Fatores de Tempo , Cloridrato de Venlafaxina/farmacocinética
8.
Surg Obes Relat Dis ; 13(8): 1369-1375, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28600115

RESUMO

BACKGROUND: Support following bariatric surgery is vital to ensure long-term postoperative success. Many individuals undergoing bariatric surgery are turning to online modalities, especially the popular social media platform Facebook, to access support groups and pages. Despite evidence suggesting that the majority of patients considering bariatric surgery are utilizing online groups, little is known about the actual content of these groups. OBJECTIVES: The purpose of the present study was to conduct a content analysis of bariatric surgery support groups and pages on Facebook. SETTING: Online via Facebook, independent academic medical center, United States. METHODS: Data from bariatric surgery-related Facebook support groups and pages were extracted over a 1-month period in 2016. Salient content themes (e.g., progress posts, depression content, eating behaviors) were coded reliably (all κ> .70). RESULTS: More than 6,800 posts and replies were coded. Results indicated that seeking recommendations (11%), providing information or recommendations (53%), commenting on changes since surgery (19%), and lending support to other members (32%) were the most common types of posts. Content surrounding anxiety, eating behaviors, depression, body image, weight bias, and alcohol was found less frequently. CONCLUSIONS: Online bariatric surgery groups can be used to receive support, celebrate physical and emotional accomplishments, provide anecdotal accounts of the "bariatric lifestyle" for preoperative patients, and comment on challenges with mental health and experiences of weight bias. Providers should become acquainted with the content commonly found in online groups and exercise caution in recommending these platforms to information-seeking patients.


Assuntos
Cirurgia Bariátrica , Obesidade Mórbida/cirurgia , Grupos de Autoajuda/estatística & dados numéricos , Mídias Sociais/estatística & dados numéricos , Apoio Social , Consumo de Bebidas Alcoólicas/psicologia , Ansiedade/psicologia , Imagem Corporal , Depressão/psicologia , Transtornos da Alimentação e da Ingestão de Alimentos/psicologia , Humanos , Saúde Mental , Obesidade Mórbida/psicologia
9.
Obes Surg ; 26(6): 1274-8, 2016 06.
Artigo em Inglês | MEDLINE | ID: mdl-26341087

RESUMO

BACKGROUND: Screening for depressive symptoms is important when evaluating bariatric surgery candidates, as worse outcomes can be seen with higher pre-surgical and post-surgical psychiatric comorbidities. The Beck Depression Inventory-II (BDI-II) and Patient Health Questionnaire (PHQ-9) are two widely used depression screening instruments. This study evaluated whether both instruments have similar performance in an outpatient bariatric surgery clinic setting. METHODS: One thousand thirty-four bariatric surgery candidates completed both PHQ-9 and BDI-II whose scores were analyzed in this retrospective study. Spearman's correlation coefficient was calculated to compare total scores on each instrument. PHQ-9 categories were compared to corresponding BDI-II categories via several different methods. Weighted kappa coefficients were calculated for (1) PHQ-9 and BDI-II categories, (2) scores ≥10 on the PHQ-9 and ≥20 on the BDI-II, and (3) the specific item of suicidality. RESULTS: Spearman's correlation was strong at 0.74. The median PHQ-9 and BDI-II scores were 5 and 9, corresponding to the mild and minimal categories, respectively. Weighted kappa analysis demonstrated a moderate association between depressive symptom categories evaluated using three methods. A moderate to substantial association was found for the suicidality item, with agreement of 92.3 %. CONCLUSIONS: PHQ-9 and BDI-II scores in patients seeking bariatric surgery are closely correlated. Categories of depressive symptom severity and responses to suicidality showed moderate to substantial agreement. When choosing an appropriate depression screening tool, these findings support the use of the PHQ-9 as a viable alternative to the BDI-II in patients seeking bariatric surgery.


Assuntos
Cirurgia Bariátrica/psicologia , Depressão/diagnóstico , Obesidade Mórbida/cirurgia , Escalas de Graduação Psiquiátrica , Adulto , Idoso , Comorbidade , Transtorno Depressivo/diagnóstico , Feminino , Humanos , Masculino , Programas de Rastreamento/métodos , Pessoa de Meia-Idade , Obesidade Mórbida/psicologia , Ambulatório Hospitalar , Questionário de Saúde do Paciente , Reprodutibilidade dos Testes , Estudos Retrospectivos , Ideação Suicida
10.
Obes Surg ; 26(7): 1559-64, 2016 07.
Artigo em Inglês | MEDLINE | ID: mdl-26464243

RESUMO

INTRODUCTION/PURPOSE: Distress intolerance is characterized by a low threshold for negative emotional experiences and lack of emotion regulation and has been shown to predict various health outcomes. As such, the primary aim of this study was to determine the association between distress tolerance and psychological variables (eating behaviors, mood, substance use, trauma history), completion of bariatric surgery, and post-bariatric surgery weight loss outcomes and follow up with a provider. MATERIALS AND METHODS: Two hundred forty-eight patients (75 % female, 89 % Caucasian) underwent a multidisciplinary evaluation for bariatric surgery and were assessed for psychiatric disorders via semi-structured clinical interview and psychometric questionnaires. RESULTS: Low distress tolerance was associated with symptoms of depression (p ≤ 0.001), anxiety (p ≤ 0.001), disordered eating behaviors (p ≤ 0.001), substance abuse (p ≤ 0.001), a history of being the victim of childhood sexual abuse (p ≤ 0.001), and with high BMI (p < .05). Patients endorsing higher levels of distress tolerance were more likely to undergo bariatric surgery (p < .01). Distress tolerance was not related to 2-year post-surgical weight loss outcomes or follow up with a provider. CONCLUSION: The ability to tolerate negative affect may be a variable that differentiates which patients undergo bariatric surgery rather than early postoperative outcomes.


Assuntos
Cirurgia Bariátrica/psicologia , Ajustamento Emocional , Transtornos Mentais/psicologia , Obesidade/psicologia , Obesidade/cirurgia , Adaptação Psicológica , Adulto , Comorbidade , Emoções , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Período Pós-Operatório , Inquéritos e Questionários , Redução de Peso
11.
Surg Obes Relat Dis ; 12(1): 165-70, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26183302

RESUMO

BACKGROUND: Food addiction (FA) may be related to poor weight loss outcomes; however, the literature on food addiction in bariatric surgery-seeking populations is limited. OBJECTIVES: The aim of the present study was to identify the prevalence of FA in a bariatric surgery-seeking population and its association with mood, problematic eating behaviors, and substance use. The relationship between prebariatric surgery food addiction screening and postsurgical outcomes was assessed. SETTING: Academic medical center. METHODS: Adult outpatients (n = 923) seeking bariatric surgery underwent psychological evaluation between January 2012 and May 2014. Patients were administered the Yale Food Addiction Scale (YFAS) to assess FA. Of the original sample, 195 patients underwent Roux-en-Y gastric bypass surgery. Patients returned for medical follow-up at 6 (n = 169) and 12 (n = 113) months postsurgery; 26 (13%) patients at 6 months and 82 (42%) patients at 12 months were lost to follow-up or had not reached 1 year postsurgery. RESULTS: Fourteen percent of patients met FA criteria. Patients positive for FA were more likely to endorse greater levels of depression, anxiety, binge eating episodes, nighttime eating syndrome, and low eating self-efficacy. No relationship was observed between FA and current substance use. FA did not predict postoperative outcomes including weight loss, rehospitalization, or attendance at follow-up medical appointments. CONCLUSIONS: FA is related to psychological distress and eating disordered behaviors among bariatric patients. However, FA was not predictive of short-term (6-12 mo) bariatric surgery outcomes. Future research should determine how FA affects long-term postoperative outcomes and mood stability.


Assuntos
Afeto , Cirurgia Bariátrica/psicologia , Comportamento Aditivo/complicações , Transtorno da Compulsão Alimentar/complicações , Depressão/complicações , Comportamento Alimentar/psicologia , Obesidade Mórbida/cirurgia , Adolescente , Adulto , Idoso , Comportamento Aditivo/epidemiologia , Comportamento Aditivo/psicologia , Transtorno da Compulsão Alimentar/epidemiologia , Transtorno da Compulsão Alimentar/psicologia , Depressão/epidemiologia , Depressão/psicologia , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade Mórbida/complicações , Obesidade Mórbida/psicologia , Prevalência , Prognóstico , Estudos Retrospectivos , Inquéritos e Questionários , Fatores de Tempo , Redução de Peso/fisiologia , Adulto Jovem
12.
J Nutr ; 145(9): 2046-51, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26246321

RESUMO

BACKGROUND: Caloric restriction alone has been shown to improve insulin action and fasting glucose metabolism; however, the mechanism by which this occurs remains uncertain. OBJECTIVE: We sought to quantify the effect of caloric restriction on ß cell function and glucose metabolism in people with type 2 diabetes. METHODS: Nine subjects (2 men, 7 women) with type 2 diabetes [BMI (in kg/m(2)): 40.6 ± 1.4; age: 58 ± 3 y; glycated hemoglobin: 6.9% ± 0.2%] were studied using a triple-tracer mixed meal after withdrawal of oral diabetes therapy. The oral minimal model was used to measure ß cell function. Caloric restriction limited subjects to a pureed diet (<900 kcal/d) for the 12 wk of study. The studies were repeated after 6 and 12 wk of caloric restriction. RESULTS: Fasting glucose concentrations decreased significantly from baseline after 6 wk of caloric restriction with no further reduction after a further 6 wk of caloric restriction (9.8 ± 1.3, 5.9 ± 0.2, and 6.2 ± 0.3 mmol/L at baseline and after 6 and 12 wk of caloric restriction, respectively; P = 0.01) because of decreased fasting endogenous glucose production (EGP: 20.4 ± 1.1, 16.2 ± 0.8, and 17.4 ± 1.1 µmol · kg(-1) · min(-1) at baseline and after 6 and 12 wk of caloric restriction, respectively; P = 0.03). These changes were accompanied by an improvement in ß cell function measured by the disposition index (189 ± 51, 436 ± 68, and 449 ± 67 10(-14) dL · kg(-1) · min(-2) · pmol(-1) at baseline and after 6 and 12 wk of caloric restriction, respectively; P = 0.01). CONCLUSIONS: Six weeks of caloric restriction lowers fasting glucose and EGP with accompanying improvements in ß cell function in people with type 2 diabetes. An additional 6 wk of caloric restriction maintained the improvement in glucose metabolism. This trial was registered at clinicaltrials.gov as NCT01094054.


Assuntos
Glicemia/metabolismo , Restrição Calórica , Diabetes Mellitus Tipo 2/dietoterapia , Células Secretoras de Insulina/metabolismo , Período Pós-Prandial , Índice de Massa Corporal , Peptídeo C/sangue , Ingestão de Energia , Jejum , Feminino , Glucagon/sangue , Hemoglobinas Glicadas/metabolismo , Humanos , Insulina/sangue , Masculino , Pessoa de Meia-Idade , Fatores de Tempo
13.
Eat Behav ; 18: 115-9, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-26042918

RESUMO

Identifying barriers to long-term adherence to reduced energy intake and increased physical activity level is critically important for obese patients seeking weight loss treatment. Previous research has identified that one such barrier is low eating self-efficacy or poor confidence in one's ability to control eating behavior in the presence of challenging situations. Accordingly, a valid, brief measure of eating self-efficacy for longitudinal assessment of weight loss and regain is needed. The purpose of this study was to test the internal consistency and clinical validity of the Weight Efficacy Lifestyle Questionnaire-Short Form (WEL-SF). Participants were 1740 consecutive obese patients who presented for a psychological evaluation in consideration for bariatric surgery. Median BMI was 44.9 (range: 35.0-111.9), age 48.7years (range: 18.9-77.3years), and patients were predominantly female (71.1%) and Caucasian (90.8%). The median WEL-SF total score was 56 (range: 0-80) and Cronbach's alpha measuring internal consistency was 0.92 with a one-factor structure. In terms of clinical validation, lower WEL-SF total scores were significantly associated with higher rates of binge eating episodes (P<0.0001), food addiction severity and dependence (P<0.0001), night eating syndrome (P<0.0001), depression (P<0.0001), and anxiety (P<0.0001). In contrast, higher WEL-SF total scores were associated with higher weight management self-efficacy (P<0.0001) and motivation to make positive lifestyle changes (P<0.0001). Taken together, these findings suggest that the WEL-SF is a psychometrically valid clinically meaningful measure of eating self-efficacy.


Assuntos
Ingestão de Alimentos/psicologia , Estilo de Vida , Autoeficácia , Inquéritos e Questionários , Adulto , Idoso , Cirurgia Bariátrica , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade/psicologia , Psicometria , Reprodutibilidade dos Testes , Adulto Jovem
14.
Obes Surg ; 25(5): 922-7, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25750006

RESUMO

BACKGROUND: A subset of bariatric patients fails to achieve or maintain long-term successful weight loss. Psychological and behavioral factors contributing to poor long-term outcomes include decreased adherence to surgical eating guidelines, life stressors that derail weight maintenance, unhealthy eating patterns, and substance use. OBJECTIVES: A 6-week pilot group behavioral intervention utilizing techniques of cognitive behavioral therapy (CBT) and dialectical behavior therapy (DBT) was developed to treat bariatric patients experiencing weight regain. SETTING: Patients were treated at a large Midwestern academic medical center. METHODS: Twenty-eight patients (93% female, 100% Caucasian) with a mean age of 53 and a mean BMI of 35.6 had regained an average of 17 kg or 37% of the weight lost after initially successful Roux-en-Y gastric bypass (RYGB). All patients completed the Structured Clinical Interview for DSM-IV-TR (SCID I) modules assessing mood and substance dependence, and completed a series of questionnaires before and after group treatment, with weekly assessment of depressive symptoms, binge eating, and alcohol use. Results were analyzed utilizing repeated measures ANOVA. RESULTS: Weight decreased during the intervention by an average of 1.6 ± 2.38 kg (p ≤ 0.01). Level of depressive symptoms improved for treatment completers (p ≤ 0.01). Food records indicated that grazing patterns decreased (p ≤ 0.01) and subjective binge eating episodes decreased (p ≤ 0.03). CONCLUSIONS: A 6-week pilot group behavioral intervention demonstrated an ability to help patients reverse their pattern of weight regain. Tailored behavioral interventions may be a useful treatment to enhance maintenance of long-term weight loss.


Assuntos
Transtorno da Compulsão Alimentar/psicologia , Obesidade Mórbida/cirurgia , Aumento de Peso , Adolescente , Adulto , Idoso , Transtorno da Compulsão Alimentar/complicações , Peso Corporal , Terapia Cognitivo-Comportamental , Feminino , Derivação Gástrica , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade Mórbida/complicações , Projetos Piloto , Período Pós-Operatório , Resultado do Tratamento , Adulto Jovem
15.
Obes Surg ; 25(10): 1917-22, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25720517

RESUMO

BACKGROUND: Chronic pain (CP) is a prevalent and disabling diagnosis in obese individuals, but how bariatric surgery patients respond to chronic pain rehabilitation treatment programs has not previously been described. OBJECTIVES: The aim of this study was to compare treatment outcomes of a chronic pain rehabilitation program (psychological and pain variables, medication use, treatment completion rates) for post-bariatric surgery patients to those of a non-bariatric surgery control group. SETTING: Three week outpatient multidisciplinary chronic pain program in an academic medical center. METHODS: This was a retrospective case-control study. Medical records of patients admitted to the Pain Rehabilitation Center at Mayo Clinic from 2008 to 2012 were reviewed. One hundred six patients with a history of bariatric surgery (cases) were identified and matched to 106 patients without a history of bariatric surgery (controls) on age, gender, and smoking status (n = 202). Matched t tests and McNemar's tests were used for analyses. RESULTS: Mean age was 46 years; 91% were female and 58% were non-smokers. The majority of cases (71%) had undergone Roux-en-Y gastric bypass. Bariatric patients had higher rates of benzodiazepine use at discharge (33 vs. 19%, p = 0.0433) and were less likely to complete treatment (87 vs. 97%, p = 0.007) compared to controls. Morphine equivalent use for cases was 127.3 mg ± 135.4 (n = 62) compared to 88.3 mg ± 95.3 (n = 62), p = 0.12, for controls at admission. CONCLUSIONS: These results suggest that bariatric patients may be at risk for treatment non-adherence and have difficulty reducing medication use in the treatment of chronic pain.


Assuntos
Cirurgia Bariátrica , Dor Crônica/reabilitação , Obesidade Mórbida/cirurgia , Adulto , Idoso , Analgésicos Opioides/uso terapêutico , Cirurgia Bariátrica/psicologia , Estudos de Casos e Controles , Dor Crônica/complicações , Dor Crônica/tratamento farmacológico , Dor Crônica/psicologia , Comorbidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Obesidade Mórbida/complicações , Obesidade Mórbida/psicologia , Estudos Retrospectivos , Resultado do Tratamento , Adulto Jovem
16.
Obes Surg ; 24(11): 1909-14, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24752620

RESUMO

BACKGROUND: Mood disorders are common among patients seeking bariatric surgery although little data exist regarding the prevalence of bipolar symptoms in this population and how they influence surgical outcomes. Our aim was to describe baseline rates of bipolar symptoms and their relationship to psychological factors and completing surgery in a sample of adults seeking bariatric surgery at an academic medical center. METHODS: We retrospectively reviewed the relationship of bipolar symptoms to demographic characteristics, baseline weight, psychological factors, and bariatric surgery completion. RESULTS: Nine hundred thirty-five patients completed the preoperative psychological evaluation. Six percent of the preoperative sample screened positive for symptoms of bipolar disorder. Patients with bipolar symptoms endorsed more robust psychopathology, trauma history, and problematic eating behaviors than patients without bipolar symptoms. Twenty-two percent of the patients with bipolar symptoms underwent bariatric surgery (n = 12), yet only 13 % were denied bariatric surgery for psychiatric reasons, suggesting that other variables may influence the completion of bariatric surgery for these patients. CONCLUSION: Prevalence rates of bipolar symptoms may be greater in patients seeking bariatric surgery compared with the general population, and few patients with bipolar symptoms actually undergo bariatric surgery. Psychological factors differentiate patients with bipolar symptoms who undergo bariatric surgery vs those who do not.


Assuntos
Cirurgia Bariátrica/psicologia , Transtorno Bipolar/psicologia , Obesidade Mórbida/cirurgia , Adulto , Transtorno Bipolar/complicações , Transtorno Bipolar/epidemiologia , Comportamento Alimentar , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Minnesota/epidemiologia , Obesidade Mórbida/complicações , Prevalência , Estudos Retrospectivos
17.
Women Health ; 53(4): 405-18, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23751093

RESUMO

UNLABELLED: Obesity rates have risen sharply in the United States, with minority women among those most affected. Although a majority of Americans are considered inactive, little attention has been devoted to studying the correlation of sedentary behavior with dietary cravings in adults. OBJECTIVE: The current study used objective and self-report methods to measure sedentary behavior and its relationship to food cravings in a sample of overweight African American and Caucasian women. DESIGN: Thirty-nine adult women (54% African American) with an average body mass index of 33.7 wore accelerometers for one week and completed self-report measures of sedentary behavior, physical activity, and food cravings. RESULTS: Self-reported television viewing time was slightly longer (3.0 versus 2.5 hours), although total sedentary time was shorter (6.7 versus 8.0 hours) on weekends versus weekdays. Weekend but not weekday sedentary time and television viewing were associated with stable aspects of food cravings rather than craving for specific foods. CONCLUSION: In this small sample, only a third of all sedentary time was attributed to viewing television. Assessing whether sedentary behavior occurs by necessity versus choice may be a factor to consider in examining its relationship to food cravings.


Assuntos
Negro ou Afro-Americano/psicologia , Comportamento Alimentar/psicologia , Comportamentos Relacionados com a Saúde/etnologia , Sobrepeso/etnologia , Comportamento Sedentário/etnologia , População Branca/psicologia , Acelerometria , Adulto , Negro ou Afro-Americano/estatística & dados numéricos , Idoso , Índice de Massa Corporal , Exercício Físico , Comportamento Alimentar/etnologia , Feminino , Humanos , Pessoa de Meia-Idade , Projetos Piloto , Fatores de Risco , Autorrelato , Fatores Socioeconômicos , Inquéritos e Questionários , Televisão/estatística & dados numéricos , Estados Unidos/epidemiologia , População Branca/estatística & dados numéricos
18.
Eat Behav ; 13(4): 375-8, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-23121791

RESUMO

Self-efficacy for eating is an important predictor of the successful adoption and maintenance of weight management behaviors. The Weight Efficacy Lifestyle Questionnaire (WEL) is a commonly used measure of eating self-efficacy consisting of 20-items and five situational factors. The aim of this study was to develop a short-form WEL (WEL-SF) for use in clinical practice and research. Factor analysis methodology was used with a sample of obese patients (N=1012) seeking weight loss treatment to develop the WEL-SF. The hypothesis was that the WEL would contain highly correlated items within the factors, and consequently could be shortened with minimal loss of clinically important information. Results revealed a one-factor solution. Given this unexpected finding, factor analysis was abandoned and alternative selection criteria were implemented. WEL-SF items were selected based upon: (1) lack of a ceiling effect for individual items, (2) high variability in patient responses, (3) lack of a strong correlation with other WEL items, (4) strong correlation with total WEL score, and (5) clinical judgment regarding importance and interpretability of individual items. These criteria resulted in an 8-item measure. The correlation between the WEL-SF total score and WEL total score was extremely strong, with a Pearson's r value of 0.968 and corresponding r(2) value of 0.937. Based on these findings, the 8-item WEL-SF appears to be a psychometrically valid measure of eating self-efficacy that accounts for 94% of the variability in the original version.


Assuntos
Comportamento Alimentar/psicologia , Obesidade/psicologia , Autoeficácia , Inquéritos e Questionários , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Cirurgia Bariátrica/psicologia , Análise Fatorial , Feminino , Humanos , Estilo de Vida , Masculino , Pessoa de Meia-Idade , Obesidade/cirurgia , Psicometria , Redução de Peso
19.
Am J Addict ; 21(4): 335-42, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22691012

RESUMO

Current efforts underway to develop the fifth edition of the Diagnostic and Statistical Manual (DSM-5) have reignited discussions for classifying the substance use disorders. This study's aim was to contribute to the understanding of abusive alcohol use and its validity as a diagnosis. Cluster analysis was used to identify relatively homogeneous groups of hazardous, nondependent drinkers by using data collected from the Prevention and Treatment of Hypertension Study (PATHS), a multisite trial that examined the ability of a cognitive-behavioral-based alcohol reduction intervention, compared to a control condition, to reduce alcohol use. Participants for this study (N = 511) were male military veterans. Variables theoretically associated with alcohol use (eg, demographic, tobacco use, and mental health) were used to create the clusters and a priori, empirically based external criteria were used to assess discriminant validity. Bivariate correlations among cluster variables were generally consistent with previous findings in the literature. Analyses of internal and discriminant validity of the identified clusters were largely nonsignificant, suggesting meaningful differences between clusters could not be identified. Although the typology literature has contributed supportive validity for the alcohol dependence diagnosis, this study's results do not lend supportive validity for the construct of alcohol abuse.


Assuntos
Consumo de Bebidas Alcoólicas/psicologia , Alcoolismo/diagnóstico , Alcoolismo/psicologia , Adaptação Psicológica , Idoso , Bebidas , Cafeína , Análise por Conglomerados , Depressão , Manual Diagnóstico e Estatístico de Transtornos Mentais , Humanos , Masculino , Pessoa de Meia-Idade , Motivação , Reprodutibilidade dos Testes , Fumar , Apoio Social , Fatores Socioeconômicos , Estresse Psicológico , Veteranos
20.
Mayo Clin Proc ; 85(8): 746-51, 2010 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-20605951

RESUMO

Eating disorders, which are associated with a host of adverse medical morbidities, negative psychological sequelae, and considerable reductions in quality of life, should be diagnosed and treated promptly. However, primary care physicians may find it uniquely challenging to detect eating disorders in their early stages, before obvious physical problems arise and while psychological symptoms are subtle. Although psychological symptoms may dominate the presentation, the physician is an integral member of the treatment team and is in a unique role to diagnose and treat eating disorders. This clinical review surveys the eating disorders literature, identified by searching MEDLINE and PubMed for articles published from January 1, 1983, to September 30, 2009, using the following keywords: anorexia nervosa, bulimia nervosa, eating disorders, eating disorders NOS, binge eating, binge eating disorder, and night eating syndrome. This review also focuses on practical issues faced by primary care physicians in the management of these conditions and other issues central to the care of these complex patients with medical and psychiatric comorbid conditions.


Assuntos
Transtornos da Alimentação e da Ingestão de Alimentos/diagnóstico , Transtornos da Alimentação e da Ingestão de Alimentos/terapia , Atenção Primária à Saúde , Humanos
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