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1.
Langenbecks Arch Surg ; 407(8): 3691-3699, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-36094764

RESUMO

PURPOSE: The influence of cancer development on long-term outcome after elective endovascular (EVAR) vs. open repair (OAR) of non-ruptured abdominal aortic aneurysms (AAA) was investigated. METHODS: Patient survival and cancer incidence were recorded for 18,802 patients registered with the AOK health insurance company in Germany who underwent EVAR (n = 14,218) and OAR (n = 4584) in the years 2010 to 2016 (men n = 16,086, women n = 2716). All patients were preoperatively and in their history cancer-free. RESULTS: 30.1% of EVAR and 27.6% of OAR patients (p ≤ .001) developed cancer after a follow-up period of up to 9 years (Kaplan-Meier estimated). Patients with cancer had a significantly less favorable outcome compared to patients with no cancer (HR 1.68; 95% CI 1.59-1.78, p < .001). After 9 years, the estimated survival of patients with and without cancer was 27.0% and 55.4%, respectively (p < .001). Survival of men and women did not differ significantly (HR 0.94; 95% CI 0.88-1.00, p = .061). In the Cox regression analysis (adjusted outcomes by operative approach, gender, age, and comorbidities), the postoperative cancer incidence was not significantly different between EVAR and OAR (HR 1.09; 95% CI 1.00-1.18, p = .051). However, EVAR showed an increased risk of postoperative development of abdominal cancer (HR 1.20; 95% CI 1.07-1.35, p = .002). 48.0% of all EVAR patients and 53.4% of all OAR patients survived in the follow-up period of up to 9 years. This difference was not significant (HR 0.96; 95% CI 0.91-1.02, p = .219). CONCLUSION: Cancer significantly worsened the long-term outcome after EVAR and OAR, without significant differences between the two repair methods in the overall cancer incidence. However, the higher abdominal cancer incidence with EVAR can affect quality of life including oncological therapy and therefore should be considered when determining the indication for surgery, and the patient should be informed about it.


Assuntos
Aneurisma da Aorta Abdominal , Implante de Prótese Vascular , Procedimentos Endovasculares , Neoplasias , Masculino , Humanos , Feminino , Aneurisma da Aorta Abdominal/epidemiologia , Aneurisma da Aorta Abdominal/cirurgia , Procedimentos Endovasculares/métodos , Qualidade de Vida , Fatores de Risco , Resultado do Tratamento , Fatores de Tempo , Estudos Retrospectivos , Implante de Prótese Vascular/efeitos adversos , Complicações Pós-Operatórias/etiologia , Neoplasias/cirurgia
2.
Chirurgie (Heidelb) ; 93(7): 702-710, 2022 Jul.
Artigo em Alemão | MEDLINE | ID: mdl-34846538

RESUMO

BACKGROUND: One of the performance criteria of a university hospital is its publication activities. The aim of this bibliometric study was a comparative benchmarking of the publication activities of German orthopedic trauma surgery university hospitals. MATERIAL AND METHODS: The publication performance of the leading groups, consisting of chief and senior physicians, section and division heads of 39 German orthopedic trauma surgery university hospitals, was recorded over a period of 10 years (1 January 2010-31 December 2019). All publications that were listed in PubMed and for which the appropriate persons were first or last author were considered. In addition, the impact factor (IF) was determined. RESULTS: A total of 4438 publications were recorded published by 381 surgeons. The share of publishing authors was 72.8%. The articles were published in 545 journals. The average IF of all publications was 1.81. The publication activities of hospitals showed a wide range, this applied to both the number of publications and the IF generated by the individual author. The publication activity ranged from an average of 16.4 publications per author in the top-ranked hospital to 1.5 publications in the last-placed hospital. The same result was seen with the total IFs. In the highest ranking hospital according to this criterion the individual surgeon achieved on average of 42.1 cumulative IFs compared with 1.7 IFs in the last placed hospital. CONCLUSION: The publication performance of German orthopedic trauma surgery university hospitals showed a high variance, as was also found in other disciplines. The causes must remain open, but a different research motivation cannot be ruled out.


Assuntos
Procedimentos Ortopédicos , Ortopedia , Cirurgiões , Bibliometria , Humanos , Editoração
3.
Langenbecks Arch Surg ; 406(5): 1659-1668, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-34309758

RESUMO

PURPOSE: The publication activity of 38 German general/visceral surgery university departments, documented by first or last authorship from staff surgeons (chief and consultants), was evaluated. METHODS: The observation period extended from 2007 to 2017 and all PubMed-listed publications were considered. Impact factor (IF) was evaluated through the publishing journal's 5-year IF in 2016, as was the IF for each individual publication. Ranking was expressed in quartiles. RESULTS: The staff surgeons of the 38 departments comprised 442 surgeons, of which only 351 (79.4%) were active as first or last authors. Four thousand six hundred and ninety-nine publications published in 702 journals were recorded. The four leading departments in publication number published as much as the last 20 departments (1330 vs. 1336 publications, respectively). The mean of the first (most active) department quartile was 19.6 publications, the second 15.4, the third 11.0, and the last quartile 7.6 per publishing surgeon. The total cumulative impact factor was 14,130. When examining the mean number of publications per publishing surgeons per the 10 year period, the mean of the first quartile was 57.9 cumulative IF, the second 45.0, the third 29.5, and the fourth quartile 17.1. With 352 (7.5%) publications, the most frequently used journal was Chirurg, followed by Langenbeck's Archives of Surgery with 274 (5.8%) publications. Pancreas-related topics led in terms of publication number and IF generated per individual publication. CONCLUSION: A significant difference in publication performance of individual departments was apparent that cannot be explained by staff number. This indicates that there are as yet unknown factors responsible for minor publication activity in many university departments.


Assuntos
Consultores , Cirurgiões , Hospitais Universitários , Humanos
4.
Urologe A ; 60(1): 59-66, 2021 Jan.
Artigo em Alemão | MEDLINE | ID: mdl-32876699

RESUMO

BACKGROUND: An improved structural and process quality could be demonstrated 13 years after certification of the first German prostate cancer center. The question of optimization of the functional quality by establishing organ cancer centers arises. OBJECTIVE: A critical benefit-risk analysis of organ cancer centers was carried out to evaluate an improved quality of results. MATERIAL AND METHODS: Based on published results from individual centers and the individual annual reports of the German Cancer Society (DKG), the data for evaluating the quality of results were checked. For the issuing of certificates, the focus is on quality indicators for oncological surgery. The functional quality of results is assessed exclusively by a questionnaire-based survey. RESULTS: An improvement in the quality of functional results after radical prostatectomy has not yet been demonstrated. The functional quality features of urinary continence and erectile function that are essential for the quality of life and patient satisfaction are only insufficiently assessed due to the lack of objective measuring instruments and are not relevant for certification. There is no reliable evidence for improved overall survival, reduction in tumor-specific mortality, and optimization of functional results in certified centers. CONCLUSION: The relationship between certification and excellence cannot be proven without individual consideration of a surgeon-specific pentafecta analysis. For this reason, certification-relevant surgeon-related quality assurance is recommended.


Assuntos
Neoplasias da Próstata , Qualidade de Vida , Certificação , Alemanha , Humanos , Masculino , Prostatectomia , Neoplasias da Próstata/cirurgia , Garantia da Qualidade dos Cuidados de Saúde
5.
Chirurg ; 92(9): 830-837, 2021 Sep.
Artigo em Alemão | MEDLINE | ID: mdl-33095283

RESUMO

BACKGROUND: The MTL30 (mortality, transfer, length of stay) was proposed as a surrogate parameter for evaluating the quality of large and potentially complication-prone visceral surgical interventions. OBJECTIVE: The aim of this study was to find out to what extent the MTL30 can be correlated with the results of the abdominal aortic aneurysm (AAA) registry of the German Institute for Vascular Health Research (DIGG) of the German Society for Vascular Surgery and Vascular Medicine (DGG) and with the case volume of the participating hospitals. MATERIAL AND METHODS: Elective endovascular abdominal aortic aneurysm repair (EVAR) was performed in 14,282 patients and open repair (OAR) in 3923 patients. Case volume of the treating hospitals, hospital mortality, length of stay and transfer to another acute care hospital were determined 30 days after the index intervention. RESULTS: The hospital mortality was 1.3% for EVAR and 4.9% for OAR (p = 0.000), the MTL30 was 5.0% and 14.4%, respectively (p = 0.000). For EVAR, no relationship between case volume and hospital mortality (quintile 1: 1.0%; quintile 5: 1.3%) as well as case volume and MTL30 (quintile 1: 5.3%; quintile 5: 5.3%) could be demonstrated. Also in OAR there was no significant relationship between case volume and hospital mortality (quintile 1: 5.8%, quintile 5: 3.5%; p = 0.505) and case volume and MTL30 (quintile 1: 16.4%, quintile 5: 12.2%, p = 0.110). With a hospital mortality rate of 7.2% (5-10%) the MTL30 for OAR was 17.6%. In both EVAR and OAR, the length of stay correlated significantly with hospital mortality and MTL30. DISCUSSION: A clear relationship between hospital case volume and hospital mortality could not be shown in the AAA registry of the DIGG. The same was true for the MTL30. It remains to be seen whether the MTL30 offers an additional benefit compared to the recording of hospital mortality and inpatient length of stay as a quality parameter.


Assuntos
Aneurisma da Aorta Abdominal , Implante de Prótese Vascular , Procedimentos Endovasculares , Aneurisma da Aorta Abdominal/cirurgia , Mortalidade Hospitalar , Humanos , Indicadores de Qualidade em Assistência à Saúde , Estudos Retrospectivos , Fatores de Risco , Fatores de Tempo , Resultado do Tratamento
6.
Chirurg ; 91(4): 329-336, 2020 Apr.
Artigo em Alemão | MEDLINE | ID: mdl-31820011

RESUMO

OBJECTIVE: The purpose of this review is to comment on the association between hospital nursing personnel staffing and patient outcomes, including the avoidance of errors and complications. METHODS: A literature search was carried out in the Medline database on publications from the last 10 years on nursing personnel staffing. RESULTS: Only overviews and observational studies on the topic were available and no controlled or prospective surveys. Most investigators assumed that there was an inverse relationship between low nursing staff levels of hospital wards and intensive care and adverse outcomes, including higher mortality rates; however, there is no clear significance for this assumption and evidence-based definitive lower limits for nursing staff cannot be given due to a lack of randomized trials. The causes for unfavorable results in the case of inadequate nursing personnel staffing include hygiene deficiencies, orders not followed and unfulfilled nursing and monitoring measures. Furthermore, staff overload leads to staff dissatisfaction and burnout, which also has a negative impact on the results. Most studies required a maximum patient to nurse ratio of 2:1 for the intensive care unit and an average ratio of not more than 8:1 for surgical wards. With respect to these requirements, changing personnel needs must be considered depending on the current state of the patients being cared for, which enabled all investigators to require a flexible roster design; approval for fixed statutory lower limits for nursing staff was low. The level of education of the nursing staff also played an essential role as qualified nursing staff cannot be replaced at will by less qualified assistant staff. CONCLUSION: The level of training and the number of the nursing personnel influence hospital mortality and adverse outcomes; however, there are no evidence-based lower levels for nursing staff for inpatient care and perhaps this cannot be the case due to the changing complexity of the patients admitted, the comorbidities and possible treatment complications. There is a considerable need for research.


Assuntos
Recursos Humanos de Enfermagem Hospitalar , Mortalidade Hospitalar , Humanos , Unidades de Terapia Intensiva , Admissão e Escalonamento de Pessoal , Estudos Prospectivos
7.
BJS Open ; 3(5): 696-703, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31592516

RESUMO

Background: Surgical publication activity in the English literature over a 10-year interval may have changed. This study sought to identify which countries make the most contributions and whether significant shifts have occurred in this time. Methods: Screening of 17 international journals in PubMed was performed for the time periods 2006-2007 and 2016-2017, for papers published by a first author belonging to a general surgical department. Data were collected by country regarding the total number of publications, cumulative impact factors (IFs), publications per inhabitant, IFs per inhabitant, and number of RCTs, meta-analyses and systematic reviews per country in both periods. Results: A total of 2247 and 3029 papers were found for 2006-2007 and 2016-2017 respectively. In 2006-2007, most papers (605, 26·9 per cent; 2697·3 IFs) came from the USA, followed by Japan (284, 12·6 per cent; 1042·1 IFs) and the UK (197, 8·8 per cent; 923·1 IFs). In 2016-2017, the USA led again with 898 papers (29·6 per cent; 4575·3 IFs), followed by Japan with 414 papers (13·7 per cent; 1556·6 IFs) and the Netherlands with 167 (5·5 per cent; 885·2 IFs). From the top 15 countries, Sweden, the Netherlands and Switzerland contributed the most articles per inhabitant during both time periods. During both periods, the UK published the most RCTs, meta-analyses and systematic reviews. Conclusion: Surgeons from the USA were the most productive in total number of publications during both time periods. However, smaller European countries were more active than the USA in relation to their population size.


Assuntos
Bibliometria/história , Cirurgia Geral/estatística & dados numéricos , Publicações/estatística & dados numéricos , História do Século XXI , Humanos , Japão/epidemiologia , Metanálise como Assunto , Países Baixos/epidemiologia , PubMed/estatística & dados numéricos , Publicações/tendências , Ensaios Clínicos Controlados Aleatórios como Assunto/estatística & dados numéricos , Cirurgiões , Suécia/epidemiologia , Suíça/epidemiologia , Revisões Sistemáticas como Assunto , Fatores de Tempo , Reino Unido/epidemiologia , Estados Unidos/epidemiologia
8.
Chirurg ; 90(11): 913-920, 2019 Nov.
Artigo em Alemão | MEDLINE | ID: mdl-31053898

RESUMO

OBJECTIVE: The aim of the study was to develop a specific risk score for the aortic register of the German Institute for Vascular Health Care Research (DIGG) of the German Society for Vascular Surgery and Vascular Medicine (DGG) for the prediction of postoperative mortality in elective treatment of intact abdominal aortic aneurysms (iAAA). The score should also enable a risk-adjusted presentation of the register results in the near future. METHODS: The method of binary logistic regression analysis was used to calculate the model. The data from 10,404 patients were included in the analysis, of whom 7870 (75.6%) were treated by endovascular (EVAR) and 2534 (24.4%) by open (OR) aortic repair. It was examined which factors have an independent influence on hospital mortality and the effect size was determined as a score. RESULTS: For EVAR, the influencing factors with their effect sizes (score in brackets) were: age >85 years (2), female gender (2), juxtarenal AAA (5), maximum diameter >65 mm (2), diabetes mellitus (2), American Society of Anesthesiologists (ASA) score >3 (2), cardiac comorbidities (3) and renal insufficiency stage >3 (5). For OR the factors were: age >80 years (2), female gender (2), juxtarenal AAA (2), ASA score >3 (3), previous myocardial infarction (2), renal comorbidities (3) and previous stroke (2). The estimated hospital mortality was calculated for the individual case from the sum of the risk factors (scores). The accuracy of the model (correlation between observed and expected results) was determined using the receiver operating characteristic (ROC) curve. An area under the curve (AUC) of 0.817 (confidence interval 0.789-0.844) demonstrated an excellent discrimination. In a validation group of 3831 patients, the good agreement between observed and calculated results was confirmed. CONCLUSION: The DIGG risk score can predict risk-adjusted hospital mortality after EVAR and OR of iAAA in the DIGG register. Improvements with respect to the prediction are desirable for OR and should be strived for by extending the model in the future.


Assuntos
Aneurisma da Aorta Abdominal , Implante de Prótese Vascular , Procedimentos Endovasculares , Aneurisma da Aorta Abdominal/mortalidade , Aneurisma da Aorta Abdominal/cirurgia , Procedimentos Cirúrgicos Eletivos , Humanos , Medição de Risco , Fatores de Risco , Resultado do Tratamento
10.
Chirurg ; 90(8): 660-667, 2019 Aug.
Artigo em Alemão | MEDLINE | ID: mdl-30610260

RESUMO

AIM: The aim of the present study was to describe the publication performance of the academic surgical management teams in Germany based on the preferred journals, their impact factors (IF) and the focal topics. METHODS: The publications of the vascular surgical management teams, consisting of chief and senior physicians, of 37 German university hospitals were analyzed. Reference date for all considerations (staffing and publications) was 1 July 2017. The publication period covered the last 10 years. The literature search was based on an evaluation of the PubMed database. RESULTS: A total of 1047 publications published in 197 journals were recorded. Among them were 3 German language journals with 136 (13.0%) publications but only 3.3% of all cumulative IFs. In 126 journals (64.0%) only one article was published and in 30 (15.2%) two articles. The three PubMed listed journals in which German university vascular surgeons published most frequently were the J Vasc Surg with 126 publications, Eur J Vasc Endovasc Surg with 94 and J Endovasc Ther with 88 publications. Of all 1047 publications 46.5% were published in an IF range under 2 and a total of 907/1047 publications (86.6%) in an IF range under 4. In 8.6% of the journals 44.1% of the IFs were generated. In terms of publication topics, thoracic and abdominal aorta were at the top of the list, accounting for almost half of all publications with 501 publications and with 52% of all 1252.08 accumulated IFs. CONCLUSION: A total of 78.6% of the publications in the 17 journals, in which more than 10 publications were made, came from independent institutions, 19.3% from the sections. None of the 91 publications in journals with an IF > 4 came from a subordinate organizational structure, indicating a gap between independent departments, sections and subordinate structures. The number of publications was based on the achievable IF of the individual topic and thus its attractiveness. Peripheral arterial disease was underrepresented in the publication topics in relation to the number of patients, with a share of 8.5.


Assuntos
Publicações Periódicas como Assunto , Publicações , Especialidades Cirúrgicas , Procedimentos Cirúrgicos Vasculares , Alemanha , Hospitais Universitários , Humanos , Fator de Impacto de Revistas
11.
Chirurg ; 90(2): 117-123, 2019 Feb.
Artigo em Alemão | MEDLINE | ID: mdl-30382296

RESUMO

The answer to the question of whether endovascular techniques extend the barriers to treatment in multimorbid vascular patients depends on the localization of the vascular disease and its stage. In multimorbid vascular patients with limited life expectancy and asymptomatic carotid stenosis, neither an endovascular nor an open procedure is indicated but a conservative best medicinal treatment is to be preferred. In symptomatic carotid stenosis the endovascular procedure is indicated for special anatomical conditions, such as contralateral carotid artery occlusion, contralateral recurrent nerve palsy, recurrent stenosis following endarterectomy, radical neck dissection and radiotherapy in the cervical region. In the treatment of intact abdominal aortic aneurysms (AAA), endovascular procedures reduce the perioperative risk especially in older patients, allowing the indications for intervention in this group of patients to be expanded, provided that the life expectancy of such treated patients is still several years. There is no clear evidence as to whether endovascular repair should be preferred in ruptured AAAs but there are indications that with the establishment of EVAR the proportion of patients receiving treatment has increased in those patients who were previously denied surgery after arrival in hospital. In critical limb ischemia the propagation of endovascular techniques has not so much extended the indications for invasive therapy but instead the endovascular approach has superseded open bypass surgery, which is positively reflected in a lower perioperative morbidity, especially in older frail patients.


Assuntos
Aneurisma da Aorta Abdominal , Implante de Prótese Vascular , Procedimentos Endovasculares , Idoso , Aneurisma da Aorta Abdominal/cirurgia , Humanos , Fatores de Risco , Resultado do Tratamento
12.
Gefasschirurgie ; 22(Suppl 1): 17-27, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28715513

RESUMO

BACKGROUND: The percutaneous infrainguinal stent (PSI) register study aimed to collate all percutaneous endovascular procedures for infrainguinal peripheral arterial occlusive disease (PAOD) conducted in 74 German vascular centers between September and November 2015 (3 months). In order to obtain representative results all consecutive treatment procedures had to be submitted by the participating trial centers. MATERIAL AND METHODS: This was a prospective, nonrandomized multicenter study design. All patients suffering from intermittent claudication (IC, Fontaine stage II) or critical limb ischemia (CLI, Fontaine stages III and IV) were included. Trial centers with less than 5 cases reported within the 3­month trial period or centers that could not ensure the submission of all treated patients were excluded. RESULTS: In the final assessment 2798 treated cases from 74 trial centers were reported of which 65 (87.8 %) centers were under the leadership of a vascular surgeon. Approximately 33 % of the interventions in centers under the leadership of vascular surgeons were conducted by radiologists. Risk factors, especially chronic renal disease, diabetes and cardiac risk factors were significantly different between patients with IC and CLI. Of the patients with Fontaine stage II PAOD 41.3 % had 3 patent crural vessels compared to only 10.8 % of patients with Fontaine stage IV. With respect to peri-interventional complications, percutaneous endovascular treatment of IC was a safe procedure with severe complications in less than 1 % and no fatalities. Only 4.5 % of the procedures were conducted under ambulatory conditions. In the supragenual region self-expanding bare metal stents, standard percutaneous transluminal angioplasty (PTA) and drug-coated balloons were the most frequently used procedures. For interventions below the knee, standard PTA was the most commonly employed treatment. CONCLUSION: The main aim of the PSI study was to obtain a realistic picture of percutaneous endovascular techniques used to treat suprapopliteal and infrapopliteal PAOD lesions and to describe the treatment procedures used by vascular specialists in Germany. To investigate the change in trends for treatment over time, this study has to be repeated in the future in order to test how quickly the results of randomized studies can be implemented in practice.

13.
Gefasschirurgie ; 21(Suppl 2): 63-70, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27546991

RESUMO

AIM: To survey the scope of vascular surgery services in Germany. METHOD: A total of 308 senior German vascular surgeons received a 19-point questionnaire pertaining to department structure and scope of services. Of these surgeons 223 replied between 16 August 2015 and 23 October 2015 (response rate 72 %), with 62.2 % reporting an additional qualification as an endovascular surgeon according to the guidelines of the German Society for Vascular Surgery and Vascular Medicine (Deutsche Gesellschaft für Gefäßchirurgie und Gefäßmedizin, DGG) and 43.5 % as a DGG® endovascular specialist. RESULTS: The number of respondents fully authorized to train in vascular surgery was 71.3 %, while 28.3 % were authorized for limited training. Authorization as a DGG® endovascular surgeon was reported by 24.2 % and authorization as a DGG® endovascular specialist by 17 % of respondents. All respondents performed endovascular interventions on pelvic vessels and 99.1 % also reported carrying out femoral and popliteal endovascular interventions. Endovascular procedures in crural vessels were carried out by 90.1 % and 93.7 % of vascular surgeons performed endovascular procedures in the region of the abdominal aorta (segment V), arteriovenous (AV) fistulas and shunts (85.2 %), upper extremity vessels (80.3 %), the thoracic aorta (segment III, 68.2 %), renal arteries (62.8 %) and visceral aorta (segment IV, 60.5 %). In all 43.5 % of respondents reported experience with endovascular procedures on the carotid bifurcation. Percutaneous arterial procedures formed the focus of endovascular activity, totalling on average 259 interventions per year and department, followed by diagnostic angiography (without intervention) at 166 procedures per year and hybrid arterial interventions at 141 interventions per year. CONCLUSION: This survey revealed a high level of endovascular expertise among vascular surgeons in Germany. This applies not only to the scope of endovascular activities in diagnosis and treatment but also to the number of estimated annual procedures.

14.
Gefasschirurgie ; 21(Suppl 2): 71-79, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27551877

RESUMO

AIM: On the basis of the CRITISCH registry outcomes in patients with critical limb ischemia (CLI) undergoing lower extremity bypass surgery were analyzed according to the site of distal anastomosis and type of bypass material. PATIENTS AND METHODS: A total of 284 patients with lower extremity bypasses consisting of 75 patients with bypasses above the knee (group 1), 80 with bypasses below the knee (group 2) and 129 crural or pedal bypasses (group 3) were included in the study. Altogether, 159 autologous saphenous vein grafts and 125 synthetic grafts were used. RESULTS: There were no perioperative complications in 191 out of the 284 patients (67.3 %) and 236 of the 284 patients (83.1 %) had open bypasses at hospital discharge. An uneventful postoperative course was observed in 76 % of the patients in group 1, 62.5 % in group 2 and 65.1 % in group 3. Amputation-free survival was 86 % at 1 year in group 1, 65 % in group 2 and 69 % in group 3. For bypasses above the knee synthetic grafts were at least not inferior to vein grafts (amputation-free survival at 1 year: prosthetic bypasses 92 % and saphenous vein grafts 71 %, p = 0.147), whereas in the crural/pedal bypass group vein grafts showed better amputation-free survival at 1 year (76 %) compared with synthetic bypasses (56 %, p = 0.105). Patients with a PREVENT III (PIII) CLI risk score ≤3 exhibited better amputation-free survival at 1 year (78 %) compared to patients with a PIII CLI risk score of 4-7 (69 %, p = 0.053). The same applied to patients with Rutherford class 4 vs. Rutherford class 6 CLI. CONCLUSION: In patients with CLI and above-knee bypasses, vein grafts confer no benefits compared with synthetic grafts for at least 1 year follow-up; however, in the case of more distal anastomoses vein grafts should be preferred.

15.
Langenbecks Arch Surg ; 401(3): 275-88, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27001684

RESUMO

PURPOSE: Abdominal aortic aneurysm is a common degenerative vascular disorder associated with sudden death due to aortic rupture. This review describes epidemiology, predisposing factors, and biology of ruptured abdominal aortic aneurysms (rAAAs). METHODS: Based on a selective literature search in Medline (PubMed), original publications, meta-analyses, systematic reviews, and Cochrane reviews were evaluated for rAAA. RESULTS: The hospital admission rate for rAAA is decreasing and is now in the range of approximately 10 per 100,000 population in men. Smoking contributes to about 50 % of population risk for rupture or surgically treated AAA. AAA rupture is a multifaceted biological process involving biochemical, cellular, and proteolytic influences, in addition to biomechanical factors. AAA rupture occurs when the stress (force per unit area) on the aneurysm wall exceeds wall strength. Proteolytic activities of matrix metalloproteinases have been implicated in aneurysm wall weakening and rupture. Aneurysm diameter is the most prominent predisposing factor for aneurysm growth and rupture. Wall stress, aneurysm shape and geometry, intraluminal thrombus, wall thickness, calcification, and metabolic activity influence the rupture risk. CONCLUSION: The best conservative option to avoid AAA rupture consists in smoking cessation and control of hypertension. Many biological factors influence rupture risk.


Assuntos
Aneurisma da Aorta Abdominal/epidemiologia , Ruptura Aórtica/epidemiologia , Aneurisma da Aorta Abdominal/patologia , Aneurisma da Aorta Abdominal/terapia , Ruptura Aórtica/patologia , Ruptura Aórtica/terapia , Humanos , Fatores de Risco
16.
Chirurg ; 87(4): 308-15, 2016 Apr.
Artigo em Alemão | MEDLINE | ID: mdl-26801751

RESUMO

Endovascular therapy has widely replaced conventional open vascular surgical reconstruction. For this reason, both techniques were widely considered to be competing approaches. Evidence-based data from randomized prospective trials, meta-analyses and clinical registries, however, demonstrated that both techniques should be used to complement each other. It became increasingly more evident that the use of either procedure depends on the underlying disease and the anatomical conditions, whereby a combination of both (hybrid approach) may be the preferred option in certain situations. This review focuses on the treatment of patients with carotid artery stenosis, intermittent claudication, critical limb ischemia and acute limb ischemia.


Assuntos
Arteriopatias Oclusivas/cirurgia , Estenose das Carótidas/cirurgia , Procedimentos Endovasculares/métodos , Procedimentos Cirúrgicos Vasculares/métodos , Doença Aguda , Extremidades/irrigação sanguínea , Humanos , Claudicação Intermitente/cirurgia , Isquemia/cirurgia
17.
Chirurg ; 87(3): 195-201, 2016 Mar.
Artigo em Alemão | MEDLINE | ID: mdl-26801752

RESUMO

Endovascular therapy has widely replaced conventional open vascular surgical reconstruction. For this reason both techniques were widely considered to be competing approaches. Evidence-based data from randomized prospective trials, meta-analyses and clinical registries, however, demonstrated that both techniques should be used to complement each other. It became increasingly more evident that the use of either procedure depends on the underlying disease and the anatomical conditions, whereby a combination of both (hybrid approach) may be the preferred option in certain situations. This review focuses on the treatment of complicated acute type B aortic dissection, descending thoracic aortic aneurysms, thoracoabdominal aortic aneurysms as well as asymptomatic and ruptured abdominal aortic aneurysms.


Assuntos
Doenças da Aorta/cirurgia , Difusão de Inovações , Procedimentos Endovasculares/tendências , Procedimentos Cirúrgicos Vasculares/tendências , Dissecção Aórtica/cirurgia , Aneurisma da Aorta Abdominal/cirurgia , Aneurisma da Aorta Torácica/cirurgia , Ruptura Aórtica/cirurgia , Fidelidade a Diretrizes , Humanos , Avaliação de Processos e Resultados em Cuidados de Saúde , Prognóstico
18.
Chirurg ; 86(11): 1041-50, 2015 Nov.
Artigo em Alemão | MEDLINE | ID: mdl-26394855

RESUMO

OBJECTIVE: This study determined whether the routine data of a single health insurance company (DAK health) can allow equivalent statements on hospital mortality of endovascular (EVAR) and open (OR) repair of intact (iAAA) and ruptured (rAAA) aortic aneurysms (AAA) in Germany in comparison to clinical registry surveys of the German Vascular Society (GVS). METHODS: The study compared two cohorts that were comparable in group sizes but not identical in terms of the duration of treatment and the selection of the centers. The GVS registry included 5080 patients with iAAA and 485 with rAAA and the DAK data consisted of 5182 patients with iAAA and 576 with rAAA. In GVS (in brackets DAK) 72.6 % (71.0 %) of patients with iAAA received EVAR and 27.4 % (29 %) OR, with rAAA 34.6 % (26.9 %) of patients received EVAR and 65.4 % (73.1 %) OR. Both cohorts were comparable with respect to patient age and gender distribution. RESULTS: Intact AAA: the hospital mortality rate in GVS (DAK in brackets) was 0.95 % (1.4 %) with EVAR and 4.7 % (5.5 %) with OR. For patients less than 80 years old the statements were almost identical when the hospital mortality in the GVS and DAK registers constituted 0.85 % and 0.9 % after EVAR and 3.8 % and 4.0 % after OR, respectively. Patients over 80 years old in particular had a benefit by EVAR as the hospital mortality in GVS (DAK in brackets) was 1.3 % (2.6 %) with EVAR vs. 13.9 % (17.4 %) with OR. A benefit by EVAR was also seen in women. Ruptured AAA: the hospital mortality rate in GVS (DAK in brackets) was 19.6 % (27.1 %) with EVAR and 38.5 % (42.0 %) with OR. Again, particularly patients over 80 years old showed an advantage with EVAR where the hospital mortality was 31.0 % (34.3 %) with EVAR vs. 56.7 % (61.3 %) with OR in this group. CONCLUSION: Hospital mortality is an important quality parameter of endovascular and open repair of iAAA and rAAA. Administrative data of a health insurance company can be used to provide representative and comprehensive statements on inhospital mortality.


Assuntos
Aneurisma Roto/mortalidade , Aneurisma Roto/cirurgia , Aneurisma da Aorta Abdominal/mortalidade , Aneurisma da Aorta Abdominal/cirurgia , Procedimentos Endovasculares/mortalidade , Mortalidade Hospitalar , Complicações Intraoperatórias/mortalidade , Programas Nacionais de Saúde/estatística & dados numéricos , Complicações Pós-Operatórias/mortalidade , Sistema de Registros/estatística & dados numéricos , Sociedades Médicas/estatística & dados numéricos , Idoso , Feminino , Alemanha , Humanos , Masculino , Fatores de Risco
19.
Zentralbl Chir ; 140(2): 219-27, 2015 Apr.
Artigo em Alemão | MEDLINE | ID: mdl-25874473

RESUMO

BACKGROUND: This overview comments on clinical trials and meta-analyses from the literature on the treatment of diabetic feet. METHODS: For the literature review, the MEDLINE database (PUBMED) was searched under the key words "diabetic foot". Publications of the last three years (2012 to 2014) were extracted. RESULTS: For patients with diabetic feet, both endovascular (ER) and open (OR) revascularisation techniques are possible. There are not sufficient data to demonstrate whether open bypass surgery or endovascular interventions are more effective in these patients. However, registries show that ER has now in terms of quantity become the preferred method. Angiosome-targeted revascularisation has to be considered in these situations. For the local treatment of a diabetic foot ulcer a variety of dressings are available, the evidence for their recommendation is low. Dressing cost and the wound management properties, e.g. exudate management therefore can influence the choice of dressing. There is no evidence that more expensive dressings as compared to basic dressings offer advantages in terms of healing. In plantar diabetic foot ulcers, non-removable off-loading devices regardless of type are more likely to result in ulcer healing than removable off-loading devices, presumably, because patient compliance with off-loading is facilitated. Meaningful pressure-relieving interventions for treating diabetic foot ulcers also include Achilles tendon lengthening, a plantar fascia release and percutaneous flexor tenotomy. The value of a standardised treatment protocol carried out by a specialist team could be proven in large registries based on decreasing amputation rates. CONCLUSION: This survey reveals a significant disparity between the large number of treatment recommendations and their evidence. For the future, therefore it is imperative to implement nationwide register surveys with respect to treatment and outcome of these patients.


Assuntos
Medicina Baseada em Evidências , Procedimentos de Cirurgia Plástica/métodos , Complicações Pós-Operatórias/etiologia , Procedimentos Cirúrgicos Vasculares/métodos , Comportamento Cooperativo , Pé/irrigação sanguínea , Humanos , Comunicação Interdisciplinar , Microcirurgia/métodos , Cuidados Pós-Operatórios/métodos , Complicações Pós-Operatórias/fisiopatologia , Sistema de Registros , Retalhos Cirúrgicos/cirurgia , Suporte de Carga/fisiologia
20.
Zentralbl Chir ; 140(1): 18-26, 2015 Feb.
Artigo em Alemão | MEDLINE | ID: mdl-25525949

RESUMO

BACKGROUND: This overview comments on the health-care relevance of peripheral arterial occlusive disease (PAOD) in patients with intermittent claudication (IC) and critical limb ischaemia (CLI). We evaluated different treatment modalities in terms of cost-effectiveness. METHOD: For the literature review, the Medline database (PubMed) was searched under the key words "critical limb ischemia AND cost", "critical limb ischemia AND economy", "peripheral arterial disease AND cost", "peripheral arterial disease AND economy". RESULTS: In the years 2005 to 2009, the hospitalisations of patients with PAOD rose disproportionately in Germany by 20 %, to 483,961 hospital admissions. By comparison, hospital admissions altogether increased by only 8 %. The average in-patient costs were estimated to be approximately € 5000 per PAOD-patient - a rather conservative estimate. For the patient with IC the economic data position is clear, supervised exercise training is by far the most cost-effective treatment option, followed by percutaneous transluminal angioplasty (PTA) and finally the peripheral bypass. In accordance with the guidelines of the UK, the latter is therefore indicated only if PTA fails or is technically not possible. In patients with CLI, the situation is not obvious. Indeed, a short-term economic advantage can be calculated for the PTA, the long-term comparison of both methods, however, is impossible due to insufficient data. In addition, the risk factors for the patient have to be included in the calculation. This was indeed demonstrated in the short-term, but could not be analysed in the long-term follow-up. CONCLUSION: The issue of greater cost-effectiveness of open or endovascular treatment in patients with CLI is uncertain, the studies and patient populations are too heterogeneous. Further studies are urgently needed to structure the sequence of the various treatment options in guidelines and clinical pathways.


Assuntos
Arteriopatias Oclusivas/economia , Arteriopatias Oclusivas/terapia , Análise Custo-Benefício/economia , Angioplastia/economia , Arteriopatias Oclusivas/epidemiologia , Artérias/cirurgia , Procedimentos Clínicos/economia , Comparação Transcultural , Estudos Transversais , Terapia por Exercício/economia , Extremidades/irrigação sanguínea , Alemanha , Fidelidade a Diretrizes/economia , Custos de Cuidados de Saúde/estatística & dados numéricos , Humanos , Claudicação Intermitente/economia , Claudicação Intermitente/epidemiologia , Claudicação Intermitente/terapia , Isquemia/economia , Isquemia/epidemiologia , Isquemia/terapia
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