RESUMO
Mycoplasma spp. are rarely recognized agents of infective endocarditis. We report a case of Mycoplasma hominis prosthetic valve endocarditis diagnosed by 16S ribosomal DNA (rDNA) PCR and culture of valves in a 74-year-old man. We reviewed the literature and found only 8 other cases reported.
Assuntos
Endocardite/diagnóstico , Endocardite/patologia , Infecções por Mycoplasma/diagnóstico , Infecções por Mycoplasma/patologia , Mycoplasma hominis/isolamento & purificação , Infecções Relacionadas à Prótese/diagnóstico , Infecções Relacionadas à Prótese/patologia , Idoso , Antibacterianos/farmacologia , DNA Bacteriano/química , DNA Bacteriano/genética , DNA Ribossômico/química , DNA Ribossômico/genética , Endocardite/microbiologia , Humanos , Masculino , Testes de Sensibilidade Microbiana , Dados de Sequência Molecular , Infecções por Mycoplasma/microbiologia , Mycoplasma hominis/classificação , Mycoplasma hominis/efeitos dos fármacos , Mycoplasma hominis/genética , Infecções Relacionadas à Prótese/microbiologia , RNA Ribossômico 16S/genética , Análise de Sequência de DNARESUMO
Guillain-Barré syndrome (GBS) is an autoimmune disease that can be triggered by different infectious agents. Here we report the case of a 26-year-old Algerian woman who developed GBS associated with a Mycobacterium bovis cervical lymphadenitis. Following intravenous immunoglobulin therapy, the patient's neurologic state returned to normal after 3 months. The lymphadenitis responded more slowly to the antituberculous treatment and an excision of necrotic cervical lymph nodes had to be performed four times. Antibiotics were administered for 16 months: ethambutol was stopped after 2 months, and rifampicin and isoniazid pursued for 14 months. An extensive etiological investigation showed that, in this case, the only likely infectious trigger GBS was the concomitant M. bovis infection. To our knowledge, this is the first report of GBS triggered by M. bovis. We performed a literature review revealing that the association between tuberculosis and Guillain-Barré syndrome is very rare (only seven cases previously reported) but is not coincidental. Physicians should be aware that tuberculosis can be a cause of GBS.
Assuntos
Síndrome de Guillain-Barré/diagnóstico , Mycobacterium bovis/isolamento & purificação , Tuberculose dos Linfonodos/complicações , Adulto , Antituberculosos/uso terapêutico , Desbridamento , Feminino , Síndrome de Guillain-Barré/terapia , Humanos , Imunoglobulinas Intravenosas/uso terapêuticoRESUMO
We described two cases of acalculous cholecystitis (AAC), due to EBV primary infection in two young Caucasian women and we reviewed other reported cases. In contrast with AAC of other etiologies, antibiotics and surgery are not useful in the management of AAC secondary to EBV.
