[The etiological structure of acute bacterial meningitis in different regions]. / Etiologicheskaia struktura ostrykh bakterial'nykh meningitov v razlichnykh regionakh.

In 1985-1989 the etiological structure of acute bacterial meningitides (ABM) in children was studied in 4 largest industrial cities in different regions of the European part of the former USSR, as well as in 2 industrial cities of western Siberia. Due to the common methodological approach used in all investigations, comparable data were obtained in all cities. These investigations revealed that meningococci caused 53.0-86.7% of all cases of ABM in children, which corresponded to moderately increased morbidity rate in meningococcal infection (3.9-11.0 cases per 100,000 of the population, mostly 5.0-7.0 cases) in these cities with its progressive decrease during 3-4 years of observation. The gradual change of meningococci from group A, prevailing in the '70s and early '80s, to group B and in some cases the appearance of group C meningococci, accompanied by a decrease in morbidity rate, were noted. In St. Petersburg the indices of ABM morbidity in children aged up to 5 years for 1987 and 1988, caused by Haemophilus influenzae (0.74 and 4.13) and pneumococci (3.23 and 4.86), could be calculated. A great number of ABM cases of unclear etiology (15.9-33.3%) suggests that the number of ABM cases caused by these two infective agents was underestimated.

[ECHO-II virus, the pathogen of the third outbreak of uveitis in children in Kransnoyarsk, 1986]. / Virus ECHO-II--vozbuditel' tret'ei vspyshki uveita u detei v Krasnoiarske (1986).

The third outbreak of an acute infection accompanied in 3 cases by inflammation of the uveal membrane (uveitis) was recorded among infants in Krasnoyarsk in 1986. From the infants with the eye involvement as well as from those in contact with the former, 36 strains of ECHO-11 virus were isolated, and seroconversion to this virus was demonstrated. All the infants in contact with the eye patients were given gamma-globulin which seemed to limit the spread of the infection. The third outbreak of uveitis, 1986, was similar to the 1st (1980-1981) and 2nd (1982) outbreaks of uveitis in Krasnoyarsk in such aspects as the clinical eye disease (anterior uveitis-iridocyclitis), symptoms of general infection, age of the infants (3-8 months), the nosocomial pattern of infection, enterovirus etiology, marked ophthalmotropism of ECHO-11 virus isolates in monkeys.

[Etiological study of uveitis in young children]. / Izuchenie étiologii uveita u detei rannego vozrasta.

The etiology of acute infectious diseases accompanied by uveitis in young children has been studied. In these investigations a high degree of contamination with virus ECHO 19 in patients with acute diseases accompanied by uveitis has been revealed and the ophthal motropic properties of the virus have been experimentally established, which indicates that certain variants of virus ECHO 19 play, probably, some role in the etiology of uveitis in young children.