RESUMO
The requirements for determining extremity dosemeter performance have evolved over the past decade. In 2010, the Spanish Nuclear Safety Council (CSN) adopted a national protocol with performance requirements based on ISO 12794. Because of the lack of symmetry of ISO 4037-3 calibration phantoms, the isotropy test set up in the sagittal plane presented several challenges both for individual monitoring services and for calibration labs. This article proposes and validates a practical approach to reduce the number of irradiations. Results show that wrist and ring dosemeters in this study meet the ISO 12794 requirements for the isotropy test. However, additional studies would be needed to verify the newer IEC 62387 Standard.
Assuntos
Dedos/efeitos da radiação , Exposição Ocupacional/análise , Imagens de Fantasmas , Dosímetros de Radiação , Monitoramento de Radiação/métodos , Proteção Radiológica/métodos , Punho/efeitos da radiação , Calibragem , Humanos , Doses de Radiação , Monitoramento de Radiação/normas , Proteção Radiológica/normas , Reprodutibilidade dos Testes , EspanhaRESUMO
With the object of studying the possible usefulness of the simultaneous plasma determination of CEA, HCG-beta and beta 2-microglobulin in patients with nontrophoblastic tumors, we measured by radioimmunoassay the concentrations of these substances in 77 patients with normal renal function. In the group without metastases (32 cases), the percentages of positives we low and similar for the 3 tumor markers. In the group with metastases (45 cases), the X2 test of independence between each of the 2 markers at a level of 95 % showed a relationship between the results obtained in the determination of HCG-beta and beta 2-microglobulin, as an independence between CEA and HCG-beta results and CEA and beta 2-microglobulin results. These data suggest the utility of determining CEA with only 1 of the other 2 antigens in disseminated tumors.
Assuntos
beta-Globulinas/análise , Antígeno Carcinoembrionário/análise , Gonadotropina Coriônica/sangue , Neoplasias/sangue , Microglobulina beta-2/análise , Feminino , Humanos , Masculino , Neoplasias/diagnósticoRESUMO
The authors evaluated by RIA the concentration of beta-2-microglobulin in pleural fluids of different origin (neoplastic, tuberculous, and others). They conclude that beta-2-microglobulin is not useful to make an etiological diagnosis.