RESUMO
Introduction: One of the probable etiologies raised in patients with chronic migraine headaches is stenosis of the lateral venous sinuses of the brain, which is detectable using magnetic resonance venography (MRV). In this study, we decided to observe the effect of adding aspirin to anti-migraine medicines on the severity of headache in patients with chronic migraine headaches with lateral venous sinus stenosis in MRV. Methods: The study was a double-blind randomized clinical trial. Patients were included in the study in two groups including 30 people. The first group was treated with propranolol and nortriptyline, and the second group was treated with propranolol, nortriptyline, and aspirin. The severity of headache, number of headaches during one month, and duration of a headache before treatment and one, two, and three months after treatment were examined. Data were analyzed utilizing SPSS software version 19 and statistical tests like t-test, Chi-squared test, Paired t-test, and repeated measure. Results: The results showed that the mean severity of headache in the second group was significantly lower than the first group two months after treatment (P = 0.003) and three months after treatment (P = 0.002). Additionally, the number of headaches (P = 0.001) and duration of headache (P = 0.043) were significantly lower in the second group than the first group in the first three months after treatment. No statistically significant difference was observed between the frequency distribution of nausea/vomiting in the two groups. Conclusion: The addition of aspirin to anti-migraine medicines is effective in improving the severity of headache in patients with migraine with lateral venous sinus stenosis of the brain.
RESUMO
BACKGROUND: The purpose of this study was to investigate the relationship between self-care management and HbA1c level of the patients with type 2 diabetes in YAZD. METHODS: This study was a cross-sectional study. The number of 376 diabetic patients referred to the Diabetes Research Center in Yazd entered the study. The data collection tool was a summary of Diabetes Self Care Activity questionnaire (SDSCA), which was collected through interviews with patients. Data analysis was performed using SPSS software V 16 and kruskalwallis and independent sample t tests. RESULTS: The results showed that of 376 patients, 218 (%58) were women and 158 (%42) were male. The mean age of the participants in the study was 54.5 ± 10.9 years old and the mean duration of the disease was 9.53 ± 8.39 years. The mean HbA1C in the patients was 7.93% ± 1.38%. The mean of BMI was 28.93 ± 6 kg/ m2. The mean of self-care score in the patients under study was 30.53 ± 11.4. There was a significant relationship between the mean of self-care score, BMI, age and HbA1C (P value <0.05). CONCLUSIONS: According to the results of the study, it can be concluded that the level of self-care in patients with controlled diabetes mellitus (HbA1C <7%) is more than patients with uncontrolled diabetes mellitus (HbA1c ≥9%).
