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1.
J Anim Sci ; 1022024 Jan 03.
Artigo em Inglês | MEDLINE | ID: mdl-38219072

RESUMO

The objective of this study was to determine the impact of 0, 1, 2, or 3 d of oral electrolyte solutions (OES) following transport on calf behavior, biochemical measures of hydration, and subsequent health. Two cohorts of 60 Holstein bull calves ~3 to 7 d of age were included in this experiment. Calves (n = 30/treatment) were randomized to 1 of 4 treatments on arrival at a calf-raising facility: (1) 1-d OES, (2) 2-d OES, (3) 3-d OES, or (4) no OES (control). Calves were evaluated for signs of arthritis, depression, dehydration, diarrhea, fever, navel inflammation, and respiratory disease on arrival (day 0) and 1, 2, 3, and 7 d after arrival. Blood was obtained following each examination to assess biochemical measures of hydration, including serum electrolytes, glucose, hematocrit, lactate, pH, and serum total protein (STP). Calves were fitted with 3D accelerometers attached to the right hind leg along the metatarsus bone to continuously measure lying time. Linear regression models with Gaussian or Poisson link functions were used to test differences between treatments in blood parameters, as well as disease frequency and behavior, respectively. Calves spent the most time lying immediately post-transport (day 0); however, there was no effect of OES treatment on lying time. On arrival, 90% (95% CI: 84.6% to 95.4%) of calves had mild to moderate dehydration, and there was no significant difference in hydration status across treatments. Mildly dehydrated calves that received 1- and 2-d OES had higher STP concentration compared to the control. Moderately dehydrated calves that received 3- vs. 1-d OES had higher (101.4 vs. 93.7 mmol/L, respectively; P = 0.01) glucose concentration, and 3- vs. 2-d OES (101.4 vs. 96.2, respectively; P = 0.07) calves tended to have higher glucose concentration. The prevalence of failed transfer of passive immunity (STP < 5.1 g/dL) and hypoglycemia (glucose < 4.95 mmol/L) was 26.7% (18.6% to 34.7%) and 76.5% (68.7% to 84.2%), respectively. The frequency of moderate dehydration was lower for calves that received 2-d OES compared to the control (count ratio: 0.4; 0.2% to 0.8%; P = 0.009). These results underline the need for more research on rehydration strategies to help inform calf processing protocols. Future research should investigate preconditioning strategies to minimize the impact of marketing and transport on dairy calves. Continued nutritional-based research is also needed to better support calves' recovery post-transport.


Most male calves are sold and transported from the dairy farm soon after birth. Typically, calves are transported without access to milk and/or water, and they often arrive at calf-raising facilities with varying degrees of dehydration. This study provided calves with 0 (control), 1, 2, or 3 consecutive days of oral electrolyte solutions following transportation and assessed calf behavior, biomarkers of hydration, and subsequent health post-transport. Most calves were dehydrated and hypoglycemic (low blood glucose levels) on arrival at the calf-raising facility. Calves spent the most time lying immediately post-transport; however, electrolytes did not impact total lying time, the number of lying bouts, or lying bout duration. Providing calves with electrolytes for 2 d improved moderate dehydration (assessed via skin tent test) compared to the control. These results suggest that providing calves with 2 consecutive days of electrolytes following transportation can improve hydration status; however, more research is needed to mitigate dehydration prior to arrival at calf-raising facilities.


Assuntos
Doenças dos Bovinos , Desidratação , Animais , Bovinos , Masculino , Desidratação/veterinária , Desidratação/terapia , Hidratação/veterinária , Diarreia/veterinária , Inflamação/veterinária , Glucose , Doenças dos Bovinos/prevenção & controle , Doenças dos Bovinos/tratamento farmacológico
2.
J Dairy Sci ; 107(6): 3885-3898, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38216040

RESUMO

Optimal early-life care of surplus calves born on dairy farms is critical for health and welfare. This cross-sectional study aimed to describe the marketing practices of male dairy calves, differences in the colostrum management between male and female calves on dairy farms, and the relationship between discrepant colostrum practices and dairy producers' attitudes toward male calf care. United States dairy producers (n = 1,000) in the states of Florida, Michigan, Ohio, Vermont, and Wisconsin were selected using stratified random sampling. A questionnaire containing questions about farm demographics, colostrum management (including quantity and timeliness of colostrum delivery), and producers' attitudes toward male calf care was mailed in February 2021. Attitudes toward male calf care were assessed using 5-point Likert scales for 10 statements regarding perceptions of the value of male calves and barriers in providing optimal care. Producer responses to questions about the quantity and timeliness of colostrum delivery between male and female calves were compared using a nonparametric Wilcoxon rank-sum test. Multivariable logistic regression models were used to investigate the association between differences in colostrum management and producers' attitudes. By May 2021, 953 surveys were delivered and 315 (33.1%) were returned with complete responses. Most producers (>90%) reported feeding equal volumes of colostrum and performing the first postbirth feeding within a similar time frame for male and female calves. However, compared with females, male calves had a longer delay to the first colostrum feeding. Approximately 40% of producers marketed their male calves through auctions, and over half (54.6%) of farms sold the male calves between 3 and 10 d of age. Large farms (≥500 lactating cows) were found to market male calves at a younger age (≤3 d of age). Most producers (>78%) believed their male calves were receiving optimal care and did not consider the workload and financial costs as obstacles to providing good care to male calves. However, those who viewed the workload as an obstacle to good care and produced organic products were marginally more likely to feed a lower volume of colostrum to male calves in the first feeding after birth. These findings suggest that interventions to improve colostrum practices should be more broadly targeted to all calves born on dairy farms, and that age at transport is markedly different between large and small farms.


Assuntos
Colostro , Indústria de Laticínios , Animais , Bovinos , Masculino , Feminino , Estudos Transversais , Inquéritos e Questionários , Marketing , Atitude
3.
Zoonoses Public Health ; 71(1): 60-70, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37792633

RESUMO

Neonatal veal calves are highly susceptible to bacterial diseases. Occasional sub-optimal early-life care and long-distance transportation result in high disease burden and antimicrobial treatment incidence. Nonetheless, judicious use of antimicrobials is necessary to mitigate the animal and human health impacts of antimicrobial resistance. The objective of this cross-sectional study was to use a clinical vignette-based survey approach to evaluate the potential for reduced group or individual therapeutic antimicrobial use. The survey included items probing the adherence to veterinary-written protocols, antimicrobial use (AMU) at the calf- and group-level, and the treatment actions to case vignettes of calf diarrhoea, pneumonia, and navel infection. The survey was mailed to all veal calf producers within two U.S. production companies (n = 32 producers in Company 1; n = 70 producers in Company 2) in February and December 2019, respectively. The overall survey response rate was 36% (21/59). Although 95% of producers reported having veterinary-written treatment protocols for diarrhoea, pneumonia, and navel infection, veal producers infrequently (<50% of the time) referenced these protocols. Veal producers were primarily trained for disease identification and treatment by observing other personnel "on-the-job" (81%). Veal producers reported a high incidence of calf diarrhoea relative to pneumonia and naval infection, a lower percentage (≤40%) of diarrhoea cases being treated individually with antimicrobials. Using clinical vignettes, our results suggest that AMU decisions among veal producers depend on the severity of clinical signs for diarrhoea and pneumonia, while navel infections are often treated with antimicrobials regardless of sign severity. Nearly two-thirds of veal producers reported treating uncomplicated cases of diarrhoea (watery stool with normal body temperature, activity, and appetite), more than previously reported from dairy producers (37.1%). Findings from this survey suggest that calf producer-focused training to guide antimicrobial treatment decisions and improve producer adherence to veterinary-written treatment protocols may have important impacts on judicious antimicrobial use.


Assuntos
Anti-Infecciosos , Doenças dos Bovinos , Pneumonia , Carne Vermelha , Humanos , Animais , Bovinos , Estados Unidos/epidemiologia , Fazendas , Estudos Transversais , Doenças dos Bovinos/tratamento farmacológico , Doenças dos Bovinos/epidemiologia , Anti-Infecciosos/uso terapêutico , Diarreia/tratamento farmacológico , Diarreia/veterinária , Diarreia/epidemiologia , Pneumonia/tratamento farmacológico , Pneumonia/veterinária
4.
Zoonoses Public Health ; 71(3): 281-293, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38110691

RESUMO

AIMS: Swine are a mixing vessel for the emergence of novel reassortant influenza A viruses (IAV). Interspecies transmission of swine-origin IAV poses a public health and pandemic risk. In the United States, the majority of zoonotic IAV transmission events have occurred in association with swine exposure at agricultural fairs. Accordingly, this human-animal interface necessitates mitigation strategies informed by understanding of interspecies transmission mechanisms in exhibition swine. Likewise, the diversity of IAV in swine can be a source for novel reassortant or mutated viruses that pose a risk to both swine and human health. METHODS AND RESULTS: In an effort to better understand those risks, here we investigated the epidemiology of IAV in exhibition swine and subsequent transmission to humans by performing phylogenetic analyses using full genome sequences from 272 IAV isolates collected from exhibition swine and 23 A(H3N2)v viruses from human hosts during 2013-2015. Sixty-seven fairs (24.2%) had at least one pig test positive for IAV with an overall estimated prevalence of 8.9% (95% CI: 8.3-9.6, Clopper-Pearson). Of the 19 genotypes found in swine, 5 were also identified in humans. There was a positive correlation between the number of human cases of a genotype and its prevalence in exhibition swine. Additionally, we demonstrated that A(H3N2)v viruses clustered tightly with exhibition swine viruses that were prevalent in the same year. CONCLUSIONS: These data indicate that multiple genotypes of swine-lineage IAV have infected humans, and highly prevalent IAV genotypes in exhibition swine during a given year are also the strains detected most frequently in human cases of variant IAV. Continued surveillance and rapid characterization of IAVs in exhibition swine can facilitate timely phenotypic evaluation and matching of candidate vaccine strains to those viruses present at the human-animal interface which are most likely to spillover into humans.


Assuntos
Vírus da Influenza A , Influenza Humana , Infecções por Orthomyxoviridae , Doenças dos Suínos , Humanos , Animais , Suínos , Estados Unidos/epidemiologia , Vírus da Influenza A/genética , Vírus da Influenza A Subtipo H3N2/genética , Filogenia , Infecções por Orthomyxoviridae/epidemiologia , Infecções por Orthomyxoviridae/veterinária , Influenza Humana/epidemiologia , Vírus Reordenados/genética
5.
Microorganisms ; 10(8)2022 Aug 16.
Artigo em Inglês | MEDLINE | ID: mdl-36014070

RESUMO

Surplus calves, which consist predominately of male calves born on dairy farms, are an underrecognized source of antimicrobial-resistant (AMR) pathogens. Current production systems for surplus calves have important risk factors for the dissemination of pathogens, including the high degree of commingling during auction and transportation and sometimes inadequate care early in life. These circumstances contribute to an increased risk of respiratory and other infectious diseases, resulting in higher antimicrobial use (AMU) and the development of AMR. Several studies have shown that surplus calves harbor AMR genes and pathogens that are resistant to critically important antimicrobials. This is a potential concern as the resistant pathogens and genes can be shared between animal, human and environmental microbiomes. Although knowledge of AMU and AMR has grown substantially in dairy and beef cattle systems, comparable studies in surplus calves have been mostly neglected in North America. Therefore, the overall goal of this narrative review is to summarize the existing literature regarding AMU and AMR in surplus dairy calf production, highlight the management practices contributing to the increased AMU and the resulting AMR, and discuss potential strategies and barriers for improved antimicrobial stewardship in surplus calf production systems.

6.
Zoonoses Public Health ; 69(4): 359-369, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-35188339

RESUMO

The use of antimicrobials in food animals and the selection of antimicrobial-resistant pathogens continue to be prominent concerns for human food safety and public health. To provide optimal stewardship programs, antimicrobial use in animal production operations must be quantified and standardized for benchmarking and creating goals, monitoring temporal trends, and identifying causes of emerging resistance. In the United States, quantified estimates of antimicrobial use are available in dairy and beef cattle, but these data have not been generated for veal calf herds. Therefore, the objective of this study was to estimate the treatment incidence (TI) of antimicrobials for eight US veal calf farms in one rearing cycle. Treatment incidences were compared between calculated doses defined by the labeled daily dose (LDD), animal-defined daily dose (ADD) from the European Medicines Agency (EMA) guideline, and the used daily dose (UDD) from the farm treatment protocols. Among eight farms, veal calves received a mean of 34.40 LDD, 34.88 ADD, and 28.68 UDD of an antimicrobial per 100 days. The lower TI based on the UDD administration was a result of higher farm protocol dosing relative to the labeled and EMA daily doses. Higher quantities of antimicrobial administration were observed in the first three weeks (day 1-21) of rearing (Tukey-adjusted p < .05). This study is the first to quantitatively estimate the TI of antimicrobials on the US veal calf operations and serves as an important step toward the development of antimicrobial stewardship programs.


Assuntos
Anti-Infecciosos , Doenças dos Bovinos , Carne Vermelha , Criação de Animais Domésticos/métodos , Animais , Antibacterianos/uso terapêutico , Anti-Infecciosos/uso terapêutico , Bovinos , Doenças dos Bovinos/tratamento farmacológico , Doenças dos Bovinos/epidemiologia , Fazendas
7.
Prev Vet Med ; 190: 105323, 2021 May.
Artigo em Inglês | MEDLINE | ID: mdl-33756433

RESUMO

Calf gastrointestinal disease remains one of the main causes of productivity and economic losses on dairy operations. The majority of pre-weaned calf mortality is attributed to diarrhea or other digestive problems. Five enteric pathogens are commonly associated with diarrhea in dairy calves, including bovine rotavirus, bovine coronavirus, Escherichia coli, Salmonella spp., and Cryptosporidium parvum. Pathogen-associated differences in health outcomes and case fatality rates have not been well-characterized. Additionally, updated prevalence estimates may reflect important changes in the epidemiology of the pathogens on dairy farms. For this cohort study, fecal samples were collected from 276 clinically ill calves across 5 central Ohio dairy farms on the first day of diarrheal diagnosis. Genomic techniques, including reverse transcription polymerase chain reaction (RT-PCR) and droplet digital polymerase chain reaction (ddPCR) were used to test for the presence of the five enteric pathogens. A Poisson regression model was used to estimate the relative risk of mortality, and a survival analysis with a Cox regression model was used to analyze time to return to a healthy clinical status by pathogen. Rotavirus was the most frequently identified at 68.1 % (188/276), followed by F5 (K99)+E. coli at 42.5 % (114/268), C. parvum at 28.4 % (66/232), coronavirus at 5.8 % (16/276), and Salmonella had the lowest prevalence at 3.7 % (10/268). Risk of mortality tended to be higher for calves infected with Salmonella (RR = 3.83; 95 %CI: 0.93, 16.02, p = 0.062); however, the time to return to a healthy clinical status was not different for different pathogens. Only farm was a significant predictor of time to return to health (p = 0.017); the within-farm median duration of signs substantially varied between 2 and 7 days. The results suggest that the prevalence and distribution of rotaviral infections is higher than reported in prior studies. With the exception of infections caused by Salmonella spp., pathogen diagnosis on the first day of diarrhea was a poor predictor of the outcome and duration of disease. These results are critical to guide the implementation of prevention measures to detect, treat, and prevent calf diarrhea.


Assuntos
Doenças dos Bovinos/microbiologia , Doenças dos Bovinos/virologia , Diarreia/veterinária , Animais , Animais Recém-Nascidos , Bovinos , Doenças dos Bovinos/epidemiologia , Doenças dos Bovinos/prevenção & controle , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/veterinária , Coronavirus Bovino/isolamento & purificação , Criptosporidiose/epidemiologia , Cryptosporidium parvum/isolamento & purificação , Indústria de Laticínios , Diarreia/epidemiologia , Diarreia/microbiologia , Diarreia/virologia , Escherichia coli/isolamento & purificação , Infecções por Escherichia coli/epidemiologia , Infecções por Escherichia coli/veterinária , Fazendas , Estudos Longitudinais , Ohio/epidemiologia , Prevalência , Rotavirus/isolamento & purificação , Infecções por Rotavirus/epidemiologia , Infecções por Rotavirus/veterinária , Salmonella/isolamento & purificação , Salmonelose Animal/epidemiologia , Resultado do Tratamento , Desmame
8.
Zoonoses Public Health ; 66(7): 861-870, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-31389666

RESUMO

Swine are known reservoirs for Clostridioides difficile, formerly known as Clostridium difficile, and transmission from swine to human farm workers is strongly suggested by previous studies. This cross-sectional study evaluated the potential role of farm environmental surfaces, including those in worker breakrooms and swine housing areas, in the possible transmission of C. difficile from swine to farm workers. Environmental surfaces and piglet faeces at 13 Ohio swine farms were sampled in 2015. Typical culturing techniques were performed to isolate C. difficile from samples, and amplification of toxin genes (tcdA, tcdB and cdtB) and PCR-ribotyping were used to genetically characterize recovered isolates. In addition, sequencing of toxin regulatory gene, tcdC, was done to identify the length of identified deletions in some isolates. A survey collected farm-level management risk factor information. Clostridioides difficile was recovered from all farms, with 42% (188/445) of samples testing positive for C. difficile. Samples collected from all on-farm locations recovered C. difficile, including farrowing rooms (60%, 107/178), breakrooms (50%, 69/138) and nursery rooms (9%, 12/129). Three ribotypes recovered from both swine and human environments (078, 412 and 005) have been previously implicated in human disease. Samples taken from farrowing rooms and breakrooms were found to have greater odds of C. difficile recovery than those taken from nursery rooms (OR = 40.5, OR = 35.6, p < .001 respectively). Farms that weaned ≥23,500 pigs per year had lower odds of C. difficile recovery as compared to farms that weaned fewer pigs (OR = 0.4, p = .01) and weekly or more frequent cleaning of breakroom counters was associated with higher odds of C. difficile recovery (OR = 11.7, p < .001). This study provides important insights into the presence and characterization of C. difficile found in human environments on swine farms and highlights how these areas may be involved in transmission of C. difficile to swine farm workers and throughout the facility.


Assuntos
Infecções por Clostridium/veterinária , Fazendas , Doenças dos Suínos/microbiologia , Animais , Clostridioides difficile/genética , Infecções por Clostridium/microbiologia , Microbiologia Ambiental , Fezes , Abrigo para Animais , Humanos , Ohio/epidemiologia , Fatores de Risco , Suínos , Zoonoses
9.
Vet Radiol Ultrasound ; 59(6): 767-776, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-29989254

RESUMO

Transitional cell carcinoma is the most common cancer of the canine urinary tract. The inconsistent appearance of transitional cell carcinoma in patients introduces error if applying mathematic models for extrapolating total tumor volume from linear measurements. Reliable techniques to assess tumor size are important for monitoring treatment response. A method comparison study was performed comparing four techniques for calculating tumor volume were compared: (1 and 2) contoured tracing of tumor margins using serial computed tomography (CT) images using pre-(1) and postintravenous (2) contrast medium studies, (3) longest three linear dimensions using CT, and (4) longest three linear dimensions on abdominal ultrasound. Volumes of the transitional cell carcinoma tumor calculated by CT tracing techniques were significantly smaller than volumes calculated with an ellipsoid mathematic model using the linear measurements (P < 0.01). Intravenous contrast medium did not significantly change the volumes calculated from tracing tumor margins on CT for observer B; however, volumes differed for observer A. The volumes extrapolated from linear measurements using CT and ultrasound did not differ significantly. The interobserver reliability was highest for the precontrast CT contoured technique and was lowest using the ultrasound linear technique. Tumor volumes differed significantly between techniques of contoured tracing of the tumor margins on serial CT images compared to calculation of tumor volume from linear dimensions. The calculated volume of a transitional cell carcinoma depends upon the technique used. Characterizing the response of urinary bladder transitional cell carcinoma tumor size to therapy differs based on the method and modality used.


Assuntos
Carcinoma de Células de Transição/veterinária , Meios de Contraste , Doenças do Cão/diagnóstico por imagem , Microscopia Acústica/veterinária , Tomografia Computadorizada por Raios X/veterinária , Carga Tumoral , Neoplasias da Bexiga Urinária/veterinária , Animais , Carcinoma de Células de Transição/diagnóstico por imagem , Cães , Feminino , Masculino , Microscopia Acústica/métodos , Reprodutibilidade dos Testes , Tomografia Computadorizada por Raios X/métodos , Neoplasias da Bexiga Urinária/diagnóstico por imagem
10.
Comp Med ; 68(2): 124-130, 2018 04 02.
Artigo em Inglês | MEDLINE | ID: mdl-29663937

RESUMO

Antimicrobial resistance (AMR) presents serious threats to human and animal health. Although AMR of pathogens is often evaluated independently between humans and animals, comparative analysis of AMR between humans and animals is necessary for zoonotic pathogens. Major surveillance systems monitor AMR of zoonotic pathogens in humans and food animals, but comprehensive AMR data in veterinary medicine is not diligently monitored for most animal species with which humans commonly contact, including NHP. The objective of this review is to provide a complete report of the prevalences of AMR among zoonotic bacteria that present the greatest threats to NHP, occupational, and public health. High prevalences of AMR exist among Shigella, Campylobacter, and Yersinia, including resistance to antimicrobials important to public health, such as macrolides. Despite improvements in regulations, standards, policies, practices, and zoonotic awareness, occupational exposures to and illnesses due to zoonotic pathogens continue to be reported and, given the documented prevalences of AMR, constitute an occupational and public health risk. However, published literature is sparse, thus indicating the need for veterinarians to proactively monitor AMR in dangerous zoonotic bacteria, to enable veterinarians to make more informed decisions to maximize antimicrobial therapy and minimize occupational risk.


Assuntos
Resistência Microbiana a Medicamentos , Primatas/microbiologia , Zoonoses/microbiologia , Animais , Antibacterianos/farmacologia , Campylobacter/efeitos dos fármacos , Humanos , Shigella/efeitos dos fármacos , Yersinia/efeitos dos fármacos , Zoonoses/tratamento farmacológico , Zoonoses/epidemiologia
11.
Comp Med ; 67(1): 79-86, 2017 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-28222842

RESUMO

As a growing threat to human and animal health, antimicrobial resistance (AMR) has become a central public-health topic. Largescale surveillance systems, such as the National Antimicrobial Resistance Monitoring System (NARMS), are now established to monitor and provide guidance regarding AMR, but comprehensive literature on AMR among NHP is sparse. This study provides data regarding current antimicrobial use strategies and the prevalence of AMR in zoonotic bacteria recovered from NHP within biomedical research institutions. We focused on 4 enteric bacteria: Shigella flexneri, Yersinia enterocolitica, Y. pseudotuberculosis, and Campylobacter jejuni. Fifteen veterinarians, 7 biomedical research institutions, and 4 diagnostic laboratories participated, providing susceptibility test results from January 2012 through April 2015. Veterinarians primarily treated cases caused by S. flexneri, Y. enterocolitica, and Y. pseudotuberculosis with enrofloxacin but treated C. jejuni cases with azithromycin and tylosin. All isolates were susceptible to the associated primary antimicrobial but often showed resistance to others. Specifically, S. flexneri isolates frequently were resistant to erythromycin (87.5%), doxycycline (73.7%), and tetracycline (38.3%); Y. enterocolitica isolates to ampicillin (100%) and cefazolin (93.6%); and C. jejuni isolates to methicillin (99.5%) and cephalothin (97.5%). None of the 58 Y. pseudotuber-culosis isolates was resistant to any tested antimicrobial. Notably, resistance patterns were not shared between this study's NHP isolates and human isolates presented by NARMS. Our findings indicate that zoonotic bacteria from NHP diagnostic samples are broadly susceptible to the antimicrobials used to treat the clinical infections. These results can help veterinarians ensure effective antimicrobial therapy and protect staff by minimizing occupational risk.


Assuntos
Antibacterianos/uso terapêutico , Infecções por Campylobacter/veterinária , Campylobacter jejuni/efeitos dos fármacos , Resistência Microbiana a Medicamentos , Infecções por Enterobacteriaceae/veterinária , Shigella flexneri/efeitos dos fármacos , Yersinia enterocolitica/efeitos dos fármacos , Yersinia pseudotuberculosis/efeitos dos fármacos , Animais , Infecções por Campylobacter/tratamento farmacológico , Infecções por Campylobacter/epidemiologia , Campylobacter jejuni/isolamento & purificação , Estudos Transversais , Infecções por Enterobacteriaceae/tratamento farmacológico , Infecções por Enterobacteriaceae/epidemiologia , Testes de Sensibilidade Microbiana/estatística & dados numéricos , Testes de Sensibilidade Microbiana/veterinária , Prevalência , Doenças dos Primatas , Primatas , Estudos Retrospectivos , Shigella flexneri/isolamento & purificação , Inquéritos e Questionários , Yersinia enterocolitica/isolamento & purificação , Yersinia pseudotuberculosis/isolamento & purificação , Zoonoses/tratamento farmacológico , Zoonoses/microbiologia
12.
Vet Radiol Ultrasound ; 57(4): 366-75, 2016 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-27038072

RESUMO

Vomiting, often caused by mechanical intestinal obstruction, is common in dogs. Equivocal radiographic signs often necessitate repeat radiographs or additional imaging procedures. For our prospective, case-controlled, accuracy study, we hypothesized the following: (1) using computed tomography (CT), radiologists will be more sensitive and specific for detecting mechanical intestinal obstruction and recommending surgery compared to using radiographs; and (2) using measurements, radiologists will be more sensitive and specific using radiographs or CT for detecting mechanical intestinal obstruction and recommending surgery. Twenty dogs had abdominal radiographs and abdominal CT. Seventeen dogs had abdominal surgery and three dogs were not obstructed based on clinical follow-up. Confidence levels (five-point scale) of three experienced radiologists for mechanical intestinal obstruction and recommending surgery were recorded before and after making selected measurements. Eight dogs had surgically confirmed mechanical intestinal obstruction, and 12 dogs did not have obstruction. For detecting mechanical intestinal obstruction, CT was more sensitive (95.8% vs. 79.2%) and specific (80.6% vs. 69.4%) compared to radiographs, but the difference was not statistically significant. For recommending surgery, radiography was more sensitive (91.7% vs. 83.3%) and specific (83.3% vs. 72.2%) than using CT, but differences were not statistically significant. We reported objective CT measurements for predicting small mechanical intestinal obstruction. By incorporating these objective data, the diagnosis of mechanical intestinal obstruction changed in five of 120 instances (radiographs and CT). In no instance (0/120), did the objective data change the recommendation for surgery. Using CT or abdominal radiographs for the detection of canine mechanical intestinal obstruction is sensitive and specific when evaluated by experienced veterinary radiologists.


Assuntos
Doenças do Cão/diagnóstico por imagem , Obstrução Intestinal/veterinária , Radiografia Abdominal/veterinária , Tomografia Computadorizada por Raios X/veterinária , Animais , Estudos de Casos e Controles , Cães , Feminino , Obstrução Intestinal/diagnóstico por imagem , Masculino , Estudos Prospectivos
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