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1.
Sensors (Basel) ; 24(8)2024 Apr 18.
Artigo em Inglês | MEDLINE | ID: mdl-38676201

RESUMO

This paper presents an enhanced version of our previously developed bio-optical transceiver, presenting a significant advancement in nanosensor technology. Using self-assembled polymers, this nanodevice is capable of electron detection while maintaining biocompatibility, an essential feature for in vivo medical biosensors. This enhancement finds significance in the field of infectious disease control, particularly in the early detection of respiratory viruses, including high-threat pathogens such as SARS-CoV-2. The proposed system harnesses bioluminescence by converting electric signaling to visible blue light, effectively opening the path of linking nano-sized mechanisms to larger-scale systems, thereby pushing the boundaries of in vivo biomedical sensing. The performance evaluation of our technology is analytical and is based on the use of Markov chains, through which we assess the bit error probability. The calculated improvements indicate that this technology qualifies as a forerunner in terms of supporting the communication needs of smaller, safer, and more efficient manufactured sensor technologies for in vivo medical applications.


Assuntos
Técnicas Biossensoriais , COVID-19 , SARS-CoV-2 , Técnicas Biossensoriais/métodos , Técnicas Biossensoriais/instrumentação , SARS-CoV-2/isolamento & purificação , COVID-19/diagnóstico , COVID-19/virologia , Humanos , Desenho de Equipamento , Polímeros/química , Cadeias de Markov
2.
Sensors (Basel) ; 23(5)2023 Mar 04.
Artigo em Inglês | MEDLINE | ID: mdl-36905022

RESUMO

Blockchain technology has been gaining great interest from a variety of sectors including healthcare, supply chain, and cryptocurrencies. However, Blockchain suffers from a limited ability to scale (i.e., low throughput and high latency). Several solutions have been proposed to tackle this. In particular, sharding has proved to be one of the most promising solutions to Blockchain's scalability issue. Sharding can be divided into two major categories: (1) Sharding-based Proof-of-Work (PoW) Blockchain protocols, and (2) Sharding-based Proof-of-Stake (PoS) Blockchain protocols. The two categories achieve good performances (i.e., good throughput with a reasonable latency), but raise security issues. This article focuses on the second category. In this paper, we start by introducing the key components of sharding-based PoS Blockchain protocols. We then briefly introduce two consensus mechanisms, namely PoS and practical Byzantine Fault Tolerance (pBFT), and discuss their use and limitations in the context of sharding-based Blockchain protocols. Next, we provide a probabilistic model to analyze the security of these protocols. More specifically, we compute the probability of committing a faulty block and measure the security by computing the number of years to fail. We achieve a number of years to fail of approximately 4000 in a network of 4000 nodes, 10 shards, and a shard resiliency of 33%.

3.
Sensors (Basel) ; 21(10)2021 May 12.
Artigo em Inglês | MEDLINE | ID: mdl-34066223

RESUMO

In the face of cooperative intelligent transportation systems (C-ITS) advancements, the inclusion of vulnerable road users (VRU), i.e., pedestrians, cyclists, and motorcyclists, has just recently become a part of the discussion. Including VRU in C-ITS presents new challenges, most notably the trade-off between the increase in VRU safety and the aggravation in channel congestion resulting from VRU-generated messages. However, previous studies mainly focus on network-related metrics without giving much consideration to VRU safety-related metrics. In this context, we evaluated such a trade-off with a study of motion-based message generation rules for VRU transmissions. The rules were analyzed using theoretical and simulation-based evaluations. In addition to studying the message generation rules using channel load metrics, such as channel busy ratio (CBR) and packet delivery ratio (PDR), we introduced a new metric: the VRU Awareness Probability (VAP). VAP uses the exchange of messages from active VRU to measure the probability of VRU detection by nearby vehicles. Results show that fixed message-filtering mechanisms reduce the overall channel load, but they could negatively impact VRU detection. We established the importance of quantifying the VRU awareness and its inclusion in C-ITS analysis because of its direct impact on VRU safety. We also discussed approaches that include VRU context and dynamism to improve the definition of message generation rules.

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