A travessia das adolescências: uma análise psicanalítica da obra "A Viagem de Chihiro" / The crossing of adolescence: a psychoanalytic analysis of "Spirited Away" / La travesía de la adolescencia: un análisis psicoanalítico de la obra "El viaje de Chihiro"

INTRODUÇÃO: A adolescência assume diferentes concepções a depender da época vivida, sendo importante refletirmos sobre essas diversas leituras. Entretanto, o foco do presente trabalho está voltado para a abordagem da psicanálise que propõe ler esse momento como uma travessia, o momento de transição para a adultez, marcada pelo surgimento de caracteres sexuais secundários e psíquicos que repercutem no encontro com o desconhecido. O filme A viagem de Chihiro conta a história de Chihiro Ogino, uma menina de dez anos que está mudando com os pais para uma nova cidade. Propomos tomar o filme como uma metáfora do adolescer na contemporaneidade e, deste modo, visamos apreender os impasses da adolescência através da trajetória vivida pela personagem Chihiro, permitindo transmitir uma reflexão sobre esse momento singular de modo lúdico. Para o desenvolvimento do estudo, a metodologia escolhida foi a pesquisa documental. METODOLOGIA: Para a articulação entre o filme e o tema da pesquisa foi realizada a construção de três eixos de leitura: os lutos inerentes ao processo de adolescência; a adolescência e o tempo lógico de Lacan e os impactos do discurso capitalista na adolescência contemporânea. DISCUSSÃO E RESULTADOS: A viagem percorrida por Chihiro representa o seu adolescer, o qual é marcado por diferentes lutos. Aos poucos, Chihiro vivencia a perda da posição infantil, também, pelas diversas novas responsabilidades que surgem na sua vida, tais como a necessidade de salvar os seus pais, aprender o funcionamento da casa de banho e lidar com as diferentes criaturas nesse novo dia a dia. Os pais da infância, que eram sinônimo de proteção e segurança, gradativamente e dolorosamente se tornam frágeis, levando Chihiro a elaborar uma outra posição subjetiva, tornando-se adulta. CONSIDERAÇÕES FINAIS: A leitura psicanalítica possibilitou um olhar para a singularidade de tal vivência, mostrando os diversos aspectos em jogo que não podem ser limitados aos parâmetros biológicos.

INTRODUCTION: The adolescence is taken by different approaches when seen in another time frame, being important to reflect about other authors. However, the focus of this present study is based on psychoanalysis which proposes to see this moment as a crossing path, a moment of transition to adulthood, characterized by the emergence of secondary sexual characteristics, as well as psychic characteristics that reverberates when it encounters the unknown. The piece Spirited Away tells the story of ten-year-old girl Chiriho Ogino, who is moving to a new city with her parents. We propose to take the film as a metaphor of adolescence in contemporary times and, in this way, we aim to apprehend the impasses of adolescence through the trajectory lived by the character Chihiro, allowing us to transmit a reflection on this singular moment in a ludic way. For developing this study, was chosen, as methodology, documentary research. METHOD: the articulation between the film and the research theme was performed through the construction of three axes of reading: the mourning inherent to the process of adolescence; adolescence and Lacan's logical time and the impacts of capitalist discourse on contemporary adolescence. RESULTS AND DISCUSSION: The traveling of Chihiro represents Chihiro's process of becoming a teenager, which is characterized by different mournings. Slowly, Chihiro lives the loss of a child position, as well as the several responsibilities that emerge from her life, such as the necessity to save her parents, the learning of bathroom operation and how to deal with different creatures in this new routine. The childhood parents, who were associated with a synonym of protection, gradually and painfully become fragile, making Chihiro elaborate herself in another subjective position, becoming an adult. FINAL CONSIDERATIONS: The psychoanalytic analysis, enables a singularity view of such experience, showing the several aspects that cannot be limited to biological parameters.

INTRODUCCIÓN: La adolescencia asume diferentes concepciones dependiendo de la época vivida, siendo importante que reflexionemos sobre esas diversas lecturas. Sin embargo, el foco del presente trabajo está volcado para el abordaje del psicoanálisis que propone leer ese momento como una travesía, el momento de transición para la adultez, marcada por el surgimiento de caracteres sexuales secundarios y psíquicos que repercuten en el encuentro con lo desconocido. La película El viaje de Chihiro cuenta la historia de Chihiro Ogino, una niña de diez años que se está mudando con los padres para una nueva ciudad. Proponemos tomar la película como una metáfora del entrar en la adolescencia en la contemporaneidad y, de este modo, intentamos aprender los impasses de la adolescencia a través de la trayectoria vivida por el personaje Chihiro, permitiendo transmitir una reflexión sobre ese momento singular de modo lúdico. Para el desarrollo del estudio, la metodología elegida fue la pesquisa documental. METODOLOGÍA: para la articulación entre la película y el tema de la pesquisa fue realizada la construcción de tres ejes de lectura: los lutos inherentes al proceso de adolescencia; la adolescencia y el tiempo lógico de Lacan y los impactos del discurso capitalista en la adolescencia contemporánea. DISCUSIÓN Y RESULTADOS: El viaje recorrido por Chihiro representa su entrar en la adolescencia, el cual es marcado por diferentes lutos. De a poco, Chihiro vive la pérdida de la posición infantil, también, por las diversas nuevas responsabilidades que surgen en su vida, tales como la necesidad de salvar a sus padres, aprender el funcionamiento de la casa de baño y a lidiar con las diferentes criaturas en ese nuevo día a día. Los padres de la infancia, que eran sinónimo de protección y seguridad, gradualmente y dolorosamente se tornan frágiles, levando a Chihiro a elaborar otra posición subjetiva, tornándose adulta. CONSIDERACIONES FINALES: La lectura psicoanalítica posibilitó una mirada para la singularidad de tal vivencia, mostrando los diversos aspectos en juego que no pueden ser limitados a los parámetros biológicos.

Giant cell arteritis with myeloperoxidase anti-neutrophil cytoplasmic antibody seropositivity in a patient with systemic sclerosis.

To the best of our knowledge, systemic sclerosis with overlapping characteristics of both microscopic polyangiitis and giant cell arteritis (i.e. microscopic polyangiitis involving the superficial temporal artery or giant cell arteritis with myeloperoxidase anti-neutrophil cytoplasmic antibody seropositivity) has not been reported previously. An 82-year-old woman with diffuse cutaneous systemic sclerosis experienced dyspnoea on exertion and fever. No signs of infection were observed on computed tomography. Her fever persisted despite antibiotic treatment for occult bacterial infection and secondary Clostridioides difficile-associated diarrhoea. Microscopic polyangiitis was suspected because of myeloperoxidase anti-neutrophil cytoplasmic antibody seropositivity, and giant cell arteritis was suspected as a differential diagnosis due to swelling of the superficial temporal artery. Arterial biopsy revealed inflammatory cell infiltration with granuloma formation. Based on the presence of granulomatous inflammation in the superficial temporal artery, we concluded that giant cell arteritis with myeloperoxidase anti-neutrophil cytoplasmic antibody seropositivity occurred as a complication. After glucocorticoid therapy, her fever and dyspnoea on exertion improved with a gradual decline in the serum myeloperoxidase anti-neutrophil cytoplasmic antibody levels. It is possible that vasculitis occurs as a complication in patients with systemic sclerosis in cases where the fever persists and cannot be explained by systemic sclerosis itself, infectious disease, or malignancy. Clinicians must be careful not to prematurely diagnose microscopic polyangiitis based on myeloperoxidase anti-neutrophil cytoplasmic antibody seropositivity or giant cell arteritis based on the swelling of the superficial temporal artery. Careful evaluation of the presence of granulomatous inflammation in an arterial biopsy specimen is essential to differentiate between microscopic polyangiitis and giant cell arteritis.

Identification of flavonoid 3'-hydroxylase in the yellow flower of Delphinium zalil.

The flowers of delphinium cultivars owe their coloration to anthocyanins such as delphinidin or pelargonidin derivatives. To date, no delphinium cultivars have been found with red flowers due to the presence of cyanidin derivatives. This suggests that delphiniums do not have cyanidin biosynthesis ability because of the loss of function of flavonoid 3' hydroxylase (F3'H). Here, we show that the wild delphinium species Delphinium zalil (synonym semibarbatum) can accumulate quercetin 3-glucosides in its sepals, presumably through F3'H activity. We isolated F3'H cDNA from D. zalil (DzF3'H) and produced a recombinant enzyme from a yeast transformant. The recombinant DzF3'H protein could convert naringenin, apigenin, dihydrokaempferol and kaempferol to eriodictyol, luteolin, dihydroquercetin and quercetin, respectively. An expression analysis confirmed that blue flowered D. grandiflorum does not express F3'H, and also showed that flavonoid 3',5'-hydroxylase and anthocyanidin synthase do not function in D. zalil sepals. DzF3'H can act as a flavonoid hydroxylase to produce cyanidin accumulation. The introduction of the DzF3'H gene into other delphinium species by conventional breeding may enable development of cultivars with novel flower colors.