Low- and moderate-intensity aerobic exercise improves the physiological acclimatization of lowlanders on the Tibetan plateau.

This study investigates whether exercise as a strategy for improving physical fitness at sea level also offers comparable benefits in the unique context of high altitudes (HA), considering the physiological challenges of hypoxic conditions. Overall, 121 lowlanders who had lived on the Tibetan Plateau for >2 years and were still living at HA during the measurements were randomly classified into four groups. Each individual of the low-intensity (LI), moderate-intensity (MI), and high-intensity (HI) groups performed 20 sessions of aerobic exercise at HA (3680 m) over 4 weeks, while the control group (CG) did not undergo any intervention. Physiological responses before and after the intervention were observed. The LI and MI groups experienced significant improvement in cardiopulmonary fitness (0.27 and 0.35 L/min increases in peak oxygen uptake [ V ˙ $\dot{\mathrm{V}}$ O2peak], both p < 0.05) after exercise intervention, while the hematocrit (HCT) remained unchanged (p > 0.05). However, HI exercise was less efficient for cardiopulmonary fitness of lowlanders (0.02 L/min decrease in V ˙ $\dot{\mathrm{V}}$ O2peak, p > 0.05), whereas both the HCT (1.74 %, p < 0.001) and glomerular filtration rate (18.41 mL/min, p < 0.001) increased with HI intervention. Therefore, LI and MI aerobic exercise, rather than HI, can help lowlanders in Tibet become more acclimated to the HA by increasing cardiopulmonary function and counteracting erythrocytosis.

High-Altitude Exposure and Time Interval Perception of Chinese Migrants in Tibet.

High-altitude exposure can negatively impact one's ability to accurately perceive time. This study focuses on Chinese migrants who have traveled to the Tibetan plateau and explores the effects of high-altitude exposure on their time interval judgment abilities based on three separate studies. In Study 1, it was found that exposure to high altitudes negatively impacted the time interval judgment functions of the migrants compared with a low-altitude control group; they exhibited a prolonged response time (540 ms: p = 0.006, 95% CI (−1.70 −0.32)) and reduced accuracy (1080 ms: p = 0.032, 95% CI (0.06 1.26)) in certain behavioral tasks. In Study 2, the results showed that high-altitude exposure and sleepiness had an interactive effect on time interval judgment (1080 ms) (p < 0.05, 95% CI (−0.83 −0.40)). To further verify our interaction hypothesis, in Study 3, we investigated the time interval judgment of interactions between acute high-altitude exposure and sleepiness level. The results revealed that the adaptation effect disappeared and sleepiness significantly exacerbated the negative effects of high-altitude exposure on time interval judgment (p < 0.001, 95% CI (−0.85 −0.34)). This study is the first to examine the effects of high-altitude exposure on time interval judgment processing functions and the effects of sleep-related factors on individual time interval judgment.

Intensity-dependent acute aerobic exercise: Effect on reactive control of attentional functions in acclimatized lowlanders at high altitude.

Human attentional function is sensitive to hypoxia. However, little is known about whether and how attentional function is altered after acute aerobic exercise at high altitude, especially for acclimatized lowlanders. In this study, we used the Attention Network Test (ANT) to measure alerting, orienting, and executive control functions and the Stroop Color and Word Test (SCWT) with a different proportion of incongruent trials to investigate proactive and reactive control of executive function. We randomly divided the sample of 160 Tibetan lowlanders who had lived in the highlands for more than two years into four groups. Each of three groups performed 20 min of low-, moderate-, or high-intensity acute aerobic exercise, separately, and a control group watched a 20-min documentary. The ANT and SCWT were conducted before and after exercise or watching the documentary. The results indicated that the executive control effects of the three experimental groups significantly decreased and, in the posttest, the executive control effects of the high-intensity group were lower than those of the low-intensity group. Furthermore, the accuracy of the moderate- and high-intensity groups was increased significantly in the blocks containing 25% incongruent trials of SCWT task. These results suggest that the acute aerobic exercise at high altitude will improve the reactive control of attentional functions in acclimatized lowlanders, and the intensity may play an important role in the exercise-cognition interaction at high altitude.

Pseudo-topotactic conversion of carbon nanotubes to T-carbon nanowires under picosecond laser irradiation in methanol.

Pseudo-topotactic conversion of carbon nanotubes into one-dimensional carbon nanowires is a challenging but feasible path to obtain desired diameters and morphologies. Here, a previously predicted but experimentally unobserved carbon allotrope, T-carbon, has been produced from pseudo-topotactic conversion of a multi-walled carbon nanotube suspension in methanol by picosecond pulsed-laser irradiation. The as-grown T-carbon nanowires have the same diameter distribution as pristine carbon nanotubes, and have been characterized by high-resolution transmission electron microscopy, fast Fourier transform, electron energy loss, ultraviolet-visible, and photoluminescence spectroscopies to possess a diamond-like lattice, where each carbon is replaced by a carbon tetrahedron, and a lattice constant of 7.80 Å. The change in entropy from carbon nanotubes to T-carbon reveals the phase transformation to be first order in nature. The computed electronic band structures and projected density of states are in good agreement with the optical absorption and photoluminescence spectra of the T-carbon nanowires.T-carbon is a previously predicted but so far unobserved allotrope of carbon, with a crystal structure similar to diamond, but with each atomic lattice position replaced by a carbon tetrahedron. Here, the authors produce T-carbon nanowires via laser-irradiating a suspension of carbon nanotubes in methanol.