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J Med Assoc Thai ; 96(6): 703-8, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-23951828

RESUMO

OBJECTIVE: To evaluate diagnostic performance of 18F-FDG PET/CT in assessment of recurrence colorectal cancer after treatment in Siriraj Hospital. MATERIAL AND METHOD: The authors retrospectively studied 48 treated colorectal cancer patients with suspected recurrence who underwent 18F-FDG PET/CT and contrast-enhanced CT (CECT). Clinical information, image follow-up for at least one year, and pathological reports of the patients were reviewed for gold standard RESULTS: Recurrent or metastatic disease was found in 36 of 48 patients. Calculated sensitivity, specificity and accuracy of 18F-FDG PET/CT were 94.4%, 66.7%, and 87.5%. 18F-FDG PET/CT can reduce false positive results of CECT in six patients, thus specificity of 18F-FDG PET/CT was statistically significantly better than that of CECT. Using lesion-based analysis with 65 recurrent sites and 26 non-recurrent lesion, 18F-FDG PET/CT showed better sensitivity 87.7%, specificity 61.5%, and accuracy 80.2 than CECT without statistical significance. CONCLUSION: 18F-FDG PET/CT overall showed higher sensitivity, specificity, and accuracy than CECT.


Assuntos
Neoplasias do Colo/diagnóstico , Fluordesoxiglucose F18 , Imagem Multimodal , Recidiva Local de Neoplasia/diagnóstico , Tomografia por Emissão de Pósitrons , Compostos Radiofarmacêuticos , Neoplasias Retais/diagnóstico , Tomografia Computadorizada por Raios X , Adulto , Idoso , Idoso de 80 Anos ou mais , Neoplasias do Colo/terapia , Meios de Contraste , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/terapia , Valor Preditivo dos Testes , Neoplasias Retais/terapia , Estudos Retrospectivos
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