The role of the electronic medical record in the assessment of health related quality of life.

We applied a hybrid Natural Language Processing (NLP) and machine learning (ML) approach (NLP-ML) to assessment of health related quality of life (HRQOL). The approach uses text patterns extracted from HRQOL inventories and electronic medical records (EMR) as predictive features for training ML classifiers. On a cohort of 200 patients, our approach agreed with patient self-report (EQ5D) and manual audit of the EMR 65-74% of the time. In an independent cohort of 285 patients, we found no association of HRQOL (by EQ5D or NLP-ML) with quality measures of metabolic control (HbA1c, Blood Pressure, Lipids). In addition; while there was no association between patient self-report of HRQOL and cost of care, abnormalities in Usual Activities and Anxiety/Depression assessed by NLP-ML were 40-70% more likely to be associated with greater health care costs. Our method represents an efficient and scalable surrogate measure of HRQOL to predict healthcare spending in ambulatory diabetes patients.

Automatic classification of foot examination findings using clinical notes and machine learning.

We examine the feasibility of a machine learning approach to identification of foot examination (FE) findings from the unstructured text of clinical reports. A Support Vector Machine (SVM) based system was constructed to process the text of physical examination sections of in- and out-patient clinical notes to identify if the findings of structural, neurological, and vascular components of a FE revealed normal or abnormal findings or were not assessed. The system was tested on 145 randomly selected patients for each FE component using 10-fold cross validation. The accuracy was 80%, 87% and 88% for structural, neurological, and vascular component classifiers, respectively. Our results indicate that using machine learning to identify FE findings from clinical reports is a viable alternative to manual review and warrants further investigation. This application may improve quality and safety by providing inexpensive and scalable methodology for quality and risk factor assessments at the point of care.