COVID-19, Coenzyme Q10 and Selenium.

In COVID-19 infection, a balance must be achieved in immune defence against the virus without precipitating a cytokine storm, which is responsible for lung injury and respiratory distress in severe cases. The initial immune response and the subsequent resolution of inflammation are likely to be dependent on nutritional status, as one contributing factor. Here, we have reviewed the potential link between two specific nutrients, coenzyme Q10 (CoQ10) and selenium, with effects on oxidative stress and inflammation in viral infection. We conclude that both reagents show promise in the treatment of patients with COVID-19 disease. This could give particular relevance over the next several months as promising vaccines are deployed to minimise the COVID-19 spread and as a potential preventative or mitigating approach for future epidemics and pandemics.

Attributional style and depression.

The study aimed to test the prediction, arising out of Abramson et al.'s (1978) reformulated learned helplessness model of depression, that depressed individuals have significantly different attributions about the causes of events from non-depressed individuals. No support was found for this hypothesis when comparing a depressed psychiatric sample with a matched normal group. Several hypotheses are offered to account for the failure to agree with previous studies.